Department of NMR-based Structural Biology

Publications

Journal Article (511)

  1. 1.
    Ikeya, T.; Ban, D.; Lee, D.; Ito, Y.; Kato, K.; Griesinger, C.: Solution NMR views of dynamical ordering of biomacromolecules. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (2), pp. 287 - 306 (2018)
  2. 2.
    Baker, J. D.; Shelton, L. B.; Zheng, D. L.; Favretto, F.; Nordhues, B. A.; Darling, A.; Sullivan, L. E.; Sun, Z. Y.; Solanki, P. K.; Martin, M. D. et al.; Suntharalingam, A.; Sabbagh, J. J.; Becker, S.; Mandelkow, E.; Uversky, V. N.; Zweckstetter, M.; Dickey, C. A.; Koren, J.; Blair, L. J.: Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biology 15 (6), e2001336 (2017)
  3. 3.
    Ban, D.; Smith, C. A.; de Groot, B. L.; Griesinger, C.; Lee, D.: Recent advances in measuring the kinetics of biomolecules by NMR relaxation dispersion spectroscopy. Archives of Biochemistry and Biophysics 628, pp. 81 - 91 (2017)
  4. 4.
    Chakrabarti, K. S.; Li, J.; Das, R.; Byrd, R. A.: Conformational dynamics and allostery in E2:E3 interactions drive ubiquitination: gp78 and Ube2g2. Structure 25 (5), pp. 794 - 805 (2017)
  5. 5.
    Chevelkov, V.; Giller, K.; Becker, S.; Lange, A.: Measurement of backbone hydrogen-deuterium exchange in the type III secretion system needle protein PrgI by solid-state NMR. Journal of Magnetic Resonace 283, pp. 110 - 116 (2017)
  6. 6.
    Cramer, J.; Schiebel, J.; Wulsdorf, T.; Grohe, K.; Najbauer, E.; Ehrmann, F. R.; Radeva, N.; Zitzer, N.; Linne, U.; Linser, R. et al.; Heine, A.; Klebe, G.: A false-positive screening hit in fragment-based lead discovery: Watch out for the red herring. Angewandte Chemie International Edition 56 (7), pp. 1908 - 1913 (2017)
  7. 7.
    Fonseca-Ornelas, L.; Schmidt, C. D.; Camacho-Zarco, A. R.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Small molecule-induced soluble oligomers of α-synuclein with helical structure. Chemistry-A European Journal (53), pp. 13010 - 13014 (2017)
  8. 8.
    Franssen, W. M. J.; van Es, S. G. D.; Dervisoglu, R.; de Wijs, G. A.; Kentgens, A. P. M.: Symmetry, dynamics, and defects in methylammonium lead alide perovskites. Journal of Physical Chemistry Letters (2017)
  9. 9.
    França, J. A.; Navarro-Vázquez, A.; Lei, X.; Sun, H.; Griesinger, C.; Hallwass, F.: Complete NMR assignment and conformational analysis of 17-α-ethinylestradiol by using RDCs obtained in grafted graphene oxide. Magnetic Resonance in Chemistry 55 (4), pp. 297 - 303 (2017)
  10. 10.
    Fredriksson, K.; Lottmann, P.; Hinz, S.; Onila, I.; Shymanets, A.; Harteneck, C.; Müller, C. E.; Griesinger, C.; Exner, T. E.: Nanodiscs for INPHARMA NMR Characterization of GPCRs: Ligand Binding to the Human A2A Adenosine Receptor. Angewandte Chemie International Edition 56 (21), pp. 5750 - 5754 (2017)
  11. 11.
    Fricke, P.; Chevelkov, V.; Zinke, M.; Giller, K.; Becker, S.; Lange, A.: Backbone assignment of perdeuterated proteins by solid-state NMR using proton detection and ultrafast magic-angle spinning. Nature Protocols 12 (4), pp. 764 - 782 (2017)
  12. 12.
    Grohe, K.; Movellan, K. T.; Vasa, S. K.; Giller, K.; Becker, S.; Linser, R.: Non-equilibrium hydrogen exchange for determination of H-bond strength and water accessibility in solid proteins. Journal of Biomolecular NMR 68 (1), pp. 7 - 17 (2017)
  13. 13.
    Haiech, J.; Heizmann, C. W.; Krebs, J.: Preface. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), pp. 841 - 842 (2017)
  14. 14.
    Jaipuria, G.; Leonov, A.; Giller, K.; Vasa, S. K.; Jaremko, Ł.; Jaremko, M.; Linser, R.; Becker, S.; Zweckstetter, M.: Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure. Nature Communications (2017)
  15. 15.
    Khan, N.; Ban, D.; Trigo-Mourino, P.; Carneiro, M. G.; Konrad, M.; Lee, D.; Sabo, T. M.: 1H, 13C and 15N resonance assignment of human guanylate kinase. Biomolecular NMR Assignments (2017)
  16. 16.
    Krebs, J.: Implications of the thyroid hormone on neuronal development with special emphasis on the calmodulin-kinase IV pathway. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), pp. 877 - 882 (2017)
  17. 17.
    Marsh, D.: Coherence transfer and electron T1-, T2-relaxation in nitroxide spin labels. Journal of Magnetic Resonance 277, pp. 86 - 94 (2017)
  18. 18.
    Martinez Hernandez, A.; Urbanke, H.; Gillman, A. L.; Lee, J.; Ryazanov, S.; Agbemenyah, H. Y.; Benito, E.; Jain, G.; Kaurani, L.; Grigorian, G. et al.; Leonov, A.; Rezaei-Ghaleh, N.; Wilken, P.; Arce, F. T.; Wagner, J.; Fuhrman, M.; Caruana, M.; Camilleri, A.; Vassallo, N.; Zweckstetter, M.; Benz, R.; Giese, A.; Schneider, A.; Korte, M.; Lal, R.; Griesinger, C.; Eichele, G.; Fischer, A.: The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine (2017)
  19. 19.
    Matthes, D.; Gapsys, V.; Griesinger, C.; de Groot, B. L.: Resolving the atomistic modes of anle138b inhibitory action on peptide oligomer formation. ACS Chemical Neuroscience (2017)
  20. 20.
    Miotto, M. C.; Pavese, M. D.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernández, C. O.: Bioinorganic chemistry of Parkinson's disease: Affinity and structural features of Cu(I) binding to the full-length β-synuclein protein. Inorganic Chemistry 56 (17), pp. 10387 - 10395 (2017)
  21. 21.
    Nath, N.; Verma, A.; Baishya , B.; Khetrapal, C. L.: Real time band selective F-1-decoupled proton NMR for the demixing of overlay spectra of chiral molecules. Magnetic Resonance in Chemistry 55 (6), pp. 553 - 558 (2017)
  22. 22.
    Reddy, J. G.; Pratihar, S.; Ban, D.; Frischkorn, S.; Becker, S.; Griesinger, C.: Simultaneous determination of fast and slow dynamics in molecules using extreme CPMG relaxation dispersion experiments. Journal of Biomolecular NMR (2017)
  23. 23.
    Reinscheid, F.; Reinscheid, U. M.: Assignment of the absolute configuration of aurantoside G and J. Journal of Molecular Structure 1147, pp. 96 - 102 (2017)
  24. 24.
    Rezaei-Ghaleh, N.; Bakhtiari, D.; Rashidi, A.: Reverse allostasis in biological systems: Minimal conditions and implications. Journal of Theoretical Biology 426, pp. 134 - 139 (2017)
  25. 25.
    Russo, L.; Giller, K.; Pfitzner, E.; Griesinger, C.; Becker, S.: Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6. Scientific Reports (2017)
  26. 26.
    Salvi, M.; Schomburg, B.; Giller, K.; Graf, S.; Unden, G.; Becker, S.; Lange, A.; Griesinger, C.: Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor. Proceedings of the National Academy of Sciences of the United States of America (2017)
  27. 27.
    Trigo-Mourino, P.; Griesinger, C.; Lee, D.: Label-free NMR-based dissociation kinetics determination. Journal of Biomolecular NMR (2017)
  28. 28.
    Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J. et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25), pp. E4971 - E4977 (2017)
  29. 29.
    Weisenburger, S.; Boening, D.; Schomburg, B.; Giller, K.; Becker, S.; Griesinger, C.; Sandoghdar, V.: Cryogenic optical localization provides 3D protein structure data with Angstrom resolution. Nature Methods 14 (2), pp. 141 - 144 (2017)
  30. 30.
    Xiang, S.; Kulminskaya, N.; Habenstein, B.; Biernat, J.; Tepper, K.; Paulat, M.; Griesinger, C.; Becker, S.; Lange, A.; Mandelkow, E. et al.; Linser, R.: A two-component adhesive: Tau fibrils arise from a combination of a well-defined motif and conformationally flexible interactions. Journal of the American Chemical Society 139 (7), pp. 2639 - 2646 (2017)
  31. 31.
    de Oliveira, R. M.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegö, E. M.; Martinho, R.; Munari, F.; Lázaro, D. F.; Moniot, S.; Guerreiro, P. et al.; Fonseca, L.; Marijanovic, Z.; Antas, P.; Gerhardt, E.; Enguita, F. J.; Fauvet, B.; Penque, D.; Pais, T. F.; Tong, Q.; Becker, S.; Kügler, S.; Lashuel, H. A.; Steegborn, C.; Zweckstetter, M.; Outeiro, T. F.: The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology (2017)
  32. 32.
    Akoury, E.; Mukrasch, M.; Biernat, J.; Tepper, K.; Ozenne, V.; Mandelkow, E.; Blackledge, M.; Zweckstetter, M.: Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer. Protein Science 25 (5), pp. 1010 - 1020 (2016)
  33. 33.
    Al-Massaedh, A.; Schmidt, M.; Pyell, U.; Reinscheid, U. M.: Elucidation of the enantiodiscrimination properties of a nonracemic chiral alignment medium through gel-based capillary electrochromatography: Separation of the mefloquine stereoisomers. ChemistryOpen (2016)
  34. 34.
    Briones, R.; Weichbrodt, C.; Paltrinieri, L.; Mey, I.; Villinger, S.; Giller, K.; Lange, A.; Zweckstetter, M.; Griesinger, C.; Becker, S. et al.; Steinem, C.; de Groot, B. L.: Voltage dependence of conformational dynamics and subconducting states of VDAC-1. Biophysical Journal 111 (6), pp. 1223 - 1234 (2016)
  35. 35.
    Carafoli, E.; Krebs, J.: Why calcium? How calcium became the best communicator. Journal of Biological Chemistry 291 (40), pp. 20849 - 20857 (2016)
  36. 36.
    Chakrabarti, K. S.; Ban, D.; Pratihar, S.; Reddy, J. G.; Becker, S.; Griesinger, C.; Lee, D.: High-power 1H composite pulse decoupling provides artifact free exchange-mediated saturation transfer (EST) experiments. Journal of Magnetic Resonance 269, pp. 65 - 69 (2016)
  37. 37.
    Draycheva, A.; Bornemann, T.; Ryazanov, S.; Lakomek, N. A.; Wintermeyer, W.: The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), pp. 152 - 167 (2016)
  38. 38.
    Fellner, L.; Kuzdas-Wood, D.; Levin, J.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b partly ameliorates motor deficits despite failure of neuroprotection in a model of advanced multiple system atrophy. Frontiers in Neuroscience (2016)
  39. 39.
    Fricke, P.; Mance, D.; Chevelkov, V.; Giller, K.; Becker, S.; Baldus, M.; Lange, A.: High resolution observed in 800 MHz DNP spectra of extremely rigid type III secretion needles. Journal of Biomolecular NMR 65 (3-4), pp. 121 - 126 (2016)
  40. 40.
    Ge, L.; Villinger, S.; Mari, S. A.; Giller, K.; Griesinger, C.; Becker, S.; Müller, D. J.; Zweckstetter, M.: Molecular plasticity of the human Voltage-Dependent Anion Channel embedded into a membrane. Structure 24 (4), pp. 585 - 594 (2016)
  41. 41.
    Gray, F.; Cho, H. J.; Shukla, S.; He, S.; Harris, A.; Boytsov, B.; Jaremko, L.; Jaremko, M.; Demeler, B.; Lawlor, E. R. et al.; Grembecka, J.; Cierpicki, T.: BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization. Nature Communications (2016)
  42. 42.
    Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S.; Zweckstetter, M.: Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand. Biomolecular NMR Assignments 10 (1), pp. 79 - 83 (2016)
  43. 43.
    Jaremko, M.; Jaremko, L.; Villinger, S.; Schmidt, C. D.; Griesinger, C.; Becker, S.; Zweckstetter, M.: High-resolution NMR determination of the dynamic structure of membrane proteins. Angewandte Chemie International Edition 55 (35), pp. 101518 - 10521 (2016)
  44. 44.
    Kulminskaya, N.; Vasa, S. K.; Giller, K.; Becker, S.; Kwan, A.; Sunde, M.; Linser, R.: Access to side-chain carbon information in deuterated solids under fast MAS through non-rotor-synchronized mixing. Chemical Communications 52 (2), pp. 268 - 271 (2016)
  45. 45.
    Kühn, J.; Wong, L. E.; Pirkuliyeva, S.; Schulz, K.; Schwiegk, C.; Fünfgeld, K.; Keppler, S.; Batista, F. D.; Urlaub, H.; Habeck, M. et al.; Becker, S.; Griesinger, C.; Wienands, J.: The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Science Signaling (2016)
  46. 46.
    Liu, L. Y.; Sun, H.; Griesinger, C.; Liu, J. K.: The use of a combination of RDC and chiroptical spectroscopy for determination of the absolute configuration of fusariumin A from the fungus Fusarium sp. Natural Products and Bioprospecting (2016)
  47. 47.
    Marsh, D.: Equation of state for phospholipid self-assembly. Biophysical Journal 110 (1), pp. 188 - 196 (2016)
  48. 48.
    Nath, N.; Schmidt, M.; Gil, R. B.; Williamson, R. T.; Martin, G. E.; Navarro-Vázquez, A.; Griesinger, C.; Liu, Y.: Determination of relative configuration from residual chemical shift anisotropy. Journal of the American Chemical Society 138 (30), pp. 9548 - 9556 (2016)
  49. 49.
    Pratihar, S.; Sabo, T. M.; Ban, D.; Fenwick, R. B.; Becker, S.; Salvatella, X.; Griesinger, C.; Lee, D.: Kinetics of the antibody recognition site in the third IgG-binding domain of protein G. Angewandte Chemie International Edition 128 (33), pp. 9719 - 9722 (2016)
  50. 50.
    Reinscheid, U. M.; Reinscheid, F.: Stereochemical analysis of menthol and menthylamine isomers using calculated and experimental optical rotation data. Journal of Molecular Structure 1103, pp. 166 - 176 (2016)
  51. 51.
    Reinscheid, F.; Reinscheid, U. M.: Stereochemical analysis of (+)-limonene using theoretical and experimental NMR and chiroptical data. Journal of Molecular Structure 1106, pp. 141 - 153 (2016)
  52. 52.
    Reinscheid, F.; Schmidt, M.; Abromeit, H.; Liening, S.; Scriba, G. K. E.; Reinscheid, U. M.: Structural and chiroptical analysis of naturally occurring (-)-strychnine. Journal of Molecular Structure 1106, pp. 200 - 209 (2016)
  53. 53.
    Saab, A. S.; Tzvetavona, I. D.; Trevisiol, A.; Baltan, S.; Dibaj, P.; K, K.; Möbius, W.; Goetze, B.; Jahn, H. M.; Huang, W. et al.; Steffens, H.; Schoburg, E. D.; Pérez-Samartín, A.; Pérez-Cerdá, F.; Bakhtiari, D.; Matute, C.; Löwel, S.; Griesinger, C.; Hirrlinger, J.; Kirchhoff, F.; Nave, K. A.: Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism. Neuron 91 (1), pp. 119 - 132 (2016)
  54. 54.
    Schewe, M.; Nematian-Ardestani, E.; Sun, H.; Musinszki, M.; Cordeiro, S.; Bucci, G.; de Groot, B. L.; Tucker, S. J.; Rapedius, M.; Baukrowitz, T.: A non-canonical voltage sensor controls gating in K2P K2 channels. Cell 164 (5), pp. 937 - 949 (2016)
  55. 55.
    Smith, C. A.; Ban, D.; Pratihar, S.; Giller, K.; Paulat, M.; Becker, S.; Griesinger, C.; Lee, D.; de Groot, B. L.: Allosteric switch regulates protein–protein binding through collective motion. Proceedings of the National Academy of Sciences of the United States of America (2016)
  56. 56.
    Tatenhorst, L.; Eckermann, K.; Dambeck, V.; Fonseca-Ornelas, L.; Walle, H.; da Fonseca, T. L.; Koch, J. C.; Becker, S.; Toenges, L.; Bahr, M. et al.; Outeiro, T. F.; Zweckstetter, M.; Lingor, P.: Fasudil attenuates aggregation of alpha-synuclein in models of Parkinson's disease. Acta Neuropathologica Communications (2016)
  57. 57.
    Tenreiro, S.; Rosado-Ramos, R.; Gerhardt, E.; Favretto, F.; Magalhães, F.; Popova, B.; Becker, S.; Zweckstetter, M.; Braus, G. H.; Outeiro, T. F.: Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Human Molecular Genetics 25 (2), pp. 275 - 290 (2016)
  58. 58.
    Vasa, S. K.; Rovo, P.; Giller, K.; Becker, S.; Linser, R.: Access to aliphatic protons as reporters in non-deuterated proteins by solid-state NMR. Physical Chemistry Chemical Physics 18 (12), pp. 8359 - 8363 (2016)
  59. 59.
    Xiang, S.; Biernat, J.; Mandelkow, E.; Becker, S.; Linser, R.: Backbone assignment for minimal protein amounts of low structural homogeneity in the absence of deuteration. Chemical Communications 52 (21), pp. 4002 - 4005 (2016)
  60. 60.
    Zong, W.; Li, G. W.; Cao, J. M.; Lei, X.; Hu, M. L.; Sun, H.; Griesinger, C.; Tan, R. X.: An alignment medium for measuring residual dipolar couplings in pure DMSO: Liquid crystals from graphene oxide grafted with polymer brushes. Angewandte Chemie-International Edition 55 (11), pp. 3690 - 3693 (2016)
  61. 61.
    Ardenkjaer-Larsen, J. H.; Boebinger, G. S.; Comment, A.; Duckett, S.; Edison, A. S.; Engelke, F.; Griesinger, C.; Griffin, R. G.; Hilty, C.; Maeda, H. et al.; Parigi, G.; Prisner, T.; Ravera, E.; van Bentum, J.; Vega, S.; Webb, A.; Luchinat, C.; Schwalbe, H.; Frydman, L.: Facing and overcoming sensitivity challenges in biomolecular NMR spectroscopy. Angewandte Chemie-International Edition 54 (32), pp. 9162 - 9185 (2015)
  62. 62.
    Cal, M.; Kotynia, A.; Jaremko, L.; Jaremko, M.; Lisowski, M.; Cebo, M.; Brasun, J.; Stefanowicz, P.: Metallacrowns as products of the aqueous medium self-assembly of histidinehydroxamic acid-containing polypeptides. Dalton Transactions 44 (24), pp. 11172 - 11181 (2015)
  63. 63.
    Camacho-Zarco, A. R.; Munari, F.; Wegstroth, M.; Liu, W. M.; Ubbink, M.; Becker, S.; Zweckstetter, M.: Multiple paramagnetic effects through a tagged reporter protein. Angewandte Chemie International Edition 54 (1), pp. 336 - 339 (2015)
  64. 64.
    Carneiro, M. G.; Koharudin, L. M.; Ban, D.; Sabo, T. M.; Trigo-Mourino, P.; Mazur, A.; Griesinger, C.; Gronenborn, A. M.; Lee, D.: Sampling of glycan-bound conformers by the anti-HIV lectin Oscillatoria agardhii agglutinin in the absence of sugar. Angewandte Chemie International Edition 54 (22), pp. 6462 - 6465 (2015)
  65. 65.
    Carneiro, M. G.; Koharudin, L. M.; Griesinger, C.; Gronenborn, A. M.; Lee, D.: 1H, 13C and 15N resonance assignment of the anti-HIV lectin from Oscillatoria agardhii. Biomolecular NMR Assignments 9 (2), pp. 317 - 319 (2015)
  66. 66.
    Carneiro, M. G.; Reddy, J. G.; Griesinger, C.; Lee, D.: Speeding-up exchange-mediated saturation transfer experiments by Fourier transform. Journal of Biomolecular NMR 63 (3), pp. 237 - 244 (2015)
  67. 67.
    Chevelkov, V.; Xiang, S.; Giller, K.; Becker, S.; Lange, A.; Reif, B.: Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization. Journal of Biomolecular NMR 61 (2), pp. 151 - 160 (2015)
  68. 68.
    Deeg, A. A.; Reiner, A. M.; Schmidt, F.; Schueder, F.; Ryazanov, S.; Ruf, V. C.; Giller, K.; Becker, S.; Leonov, A.; Griesinger, C. et al.; Giese, A.; Zinth, W.: Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates. Biochimica et Biophysica Acta-General Subjects 1850 (9), pp. 1884 - 1890 (2015)
  69. 69.
    Demers, J. P.; Vijayan, V.; Lange, A.: Recovery of bulk proton magnetization and sensitivity enhancement in ultrafast magic-angle spinning solid-state NMR. The Journal of Physical Chemistry B 119 (7), pp. 2908 - 2920 (2015)
  70. 70.
    Fasshuber, H. K.; Lakomek, N. A.; Habenstein, B.; Loquet, A.; Shi, C.; Giller, K.; Wolff, S.; Becker, S.; Lange, A.: Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR. Protein Science 24 (5), pp. 592 - 598 (2015)
  71. 71.
    Fasshuber, H. K.; Demers, J. P.; Chevelkov, V.; Giller, K.; Becker, S.; Lange, A.: Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies. Journal of Magnetic Resonance 252, pp. 10 - 19 (2015)
  72. 72.
    Gattin, Z.; Schneider, R.; Laukat, Y.; Giller, K.; Maier, E.; Zweckstetter, M.; Griesinger, C.; Benz, R.; Becker, S.; Lange, A.: Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2. Journal of Biomolecular NMR 61 (3-4), pp. 311 - 320 (2015)
  73. 73.
    Guzzi, R.; Bartucci, R.; Esmann, M.; Marsh, D.: Lipid librations at the interface with the Na,K-ATPase. Biophysical Journal 108 (12), pp. 2825 - 2832 (2015)
  74. 74.
    Habenstein, B.; Loquet, A.; Hwan, S.; Giller, K.; Vasa, S. K.; Becker, S.; Habeck, M.; Lange, A.: Hybrid structure of the type 1 pilus of uropathogenic Escherichia coli. Angewandte Chemie International Edition 54 (40), pp. 11691 - 11695 (2015)
  75. 75.
    Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S.; Zweckstetter, M.: Structural integrity of the A147T polymorph of mammalian TSPO. ChemBioChem 16 (10), pp. 1483 - 1489 (2015)
  76. 76.
    Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S.; Zweckstetter, M.: Conformational flexibility in the transmembrane protein TSPO. Chemistry-A European Journal 21 (46), pp. 16555 - 16563 (2015)
  77. 77.
    Jaremko, M.; Jaremko, L.; Jaipuria, G.; Becker, S.; Zweckstetter, M.: Structure of the mammalian TSPO/PBR protein. Biochemical Society Transactions (2015)
  78. 78.
    Jaremko, L.; Jaremko, M.; Nowakowski, M.; Ejchart, A.: The quest for simplicity: Remarks on the free-approach models. Journal of Physical Chemistry B 119 (36), pp. 11978 - 11987 (2015)
  79. 79.
    Kadavath, H.; Jaremko, M.; Jaremko, L.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Folding of the Tau protein on microtubules. Angewandte Chemie International Edition 54 (35), pp. 10347 - 10351 (2015)
  80. 80.
    Kim, D. H.; Lee, C.; Cho, Y. J.; Lee, S. H.; Cha, E. J.; Lim, J. E.; Sabo, T. M.; Griesinger, C.; Lee, D.; Han, K. H.: A pre-structured helix in the intrinsically disordered 4EBP1. Molecular BioSystems 11 (2), pp. 366 - 369 (2015)
  81. 81.
    Krebs, J.: The plethora of PMCA isoforms: Alternative splicing and differential expression. Biochimica et Biophysica Acta - Molecular Cell Research 1853 (9), pp. 2018 - 2024 (2015)
  82. 82.
    Krebs, J.; Agellon, L. B.; Michalak, M.: Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling. Biochemical and Biophysical Research Communications 460 (1), pp. 114 - 121 (2015)
  83. 83.
    Kuban-Jankowska, A.; Gorska, M.; Jaremko, L.; Jaremko, M.; Tuszynski, J. A.; Wozniak, M.: The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases. BioMetals 28 (6), pp. 975 - 986 (2015)
  84. 84.
    Kulminskaya, N.; Vasa, S. K.; Giller, K.; Becker, S.; Linser, R.: Asynchronous through-bond homonuclear isotropic mixing: Application to carbon-carbon transfer in perdeuterated proteins under MAS. Journal of Biomolecular NMR 63 (3), pp. 245 - 253 (2015)
  85. 85.
    Marsh, D.: Bonding in nitroxide spin labels from 14N electric-quadrupole interactions. The Journal of Physical Chemistry A 119 (5), pp. 919 - 921 (2015)
  86. 86.
    Mbefo, M. K.; Fares, M. B.; Paleologou, K.; Oueslati, A.; Yin, G.; Tenreiro, S.; Pinto, M.; Outeiro, T.; Zweckstetter, M.; Masliah, E. et al.; Lashuel, H. A.: Parkinson disease mutant E46K enhances alpha-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. Journal of Biological Chemistry (2015)
  87. 87.
    Miotto, M. C.; Valiente-Gabioud, A. A.; Rossetti, G.; Zweckstetter, M.; Carloni, P.; Selenko, P.; Griesinger, C.; Binolfi, A.; Fernández, C. O.: Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding. Journal of the American Chemical Society 137 (20), pp. 6444 - 6447 (2015)
  88. 88.
    Moree, B.; Yin, G.; Lazaro, D. F.; Munari, F.; Strohäker, T.; Giller, K.; Becker, S.; Outeiro, T. F.; Zweckstetter, M.; Salafsky, J.: Small molecules detected by second-harmonic generation modulate the conformation of monomeric α-synuclein and reduce its aggregation in cell. Journal of Biological Chemistry (2015)
  89. 89.
    Nath, N.; d'Auvergne, E. J.; Griesinger, C.: Long range residual dipolar couplings: A tool for determining the configuration of small molecules. Angewandte Chemie International Edition 54 (43), pp. 12706 - 12710 (2015)
  90. 90.
    Oliveira, L. M. A.; Falomir, L. J.; Gralle Botelho, M.; Lin, K. H.; Wales, P.; Koch, J.; Gerhardt, E.; Taschenberger, H.; Outeiro, T. F.; Lingor, P. et al.; Schüle, B.; Arndt-Jovin, D. J.; Jovin, T. M.: Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells. Cell Death and Disease (2015)
  91. 91.
    Onila, I.; ten Brink, T.; Fredriksson, K.; Codutti, L.; Mazur, A.; Griesinger, C.; Carlomagno, T.; Exner, T. E.: On-the-fly integration of data from a spin-diffusion-based NMR experiment into protein–ligand docking. Journal of Chemical Information and Modeling 55 (9), pp. 1962 - 1972 (2015)
  92. 92.
    Pilger, J.; Mazur, A.; Monecke, P.; Schreuder, H.; Elshorst, B.; Bartoschek, S.; Langer, T.; Schiffer, A.; Krimm, I.; Wegstroht, M. et al.; Lee, D.; Hessler, G.; Wendt, K. U.; Becker, S.; Griesinger, C.: A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angewandte Chemie International Edition 54 (22), pp. 6511 - 6515 (2015)
  93. 93.
    Rovo, P.; Grohe, K.; Giller, K.; Becker, S.; Linser, R.: Proton transverse relaxation as a sensitive probe for structure determination in solid proteins. ChemPhysChem 16 (18), pp. 3791 - 3796 (2015)
  94. 94.
    Sabo, T. M.; Trent, J. O.; Lee, D.: Population shuffling between ground and high energy excited states. Protein Science 24 (11), pp. 1714 - 1719 (2015)
  95. 95.
    Shi, S.; Wagner, J.; Mitteregger-Kretzschmar, G.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: Quantitative real-time quaking-induced conversion allows monitoring of disease-modifying therapy in the urine of prion-infected mice. Journal of Neuropathology and Experimental Neurology 74 (9), pp. 924 - 933 (2015)
  96. 96.
    Smith, C. A.; Ban, D.; Pratihar, S.; Giller, K.; Schwiegk, C.; de Groot, B. L.; Becker, S.; Griesinger, C.; Lee, D.: Population shuffling of protein conformations. Angewandte Chemie International Edition 54 (1), pp. 207 - 210 (2015)
  97. 97.
    Wagner, J.; Krauss, S.; Shi, S.; Ryazanov, S.; Steffen, J.; Miklitz, C.; Leonov, A.; Kleinknecht, A.; Göricke, B.; Weishaupt, J. H. et al.; Weckbecker, D.; Reiner, A. M.; Zinth, W.; Levin, J.; Ehninger, D.; Remy, S.; Kretzschmar, H. A.; Griesinger, C.; Giese, A.; Fuhrmann, M.: Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathologica 130 (5), pp. 619 - 631 (2015)
  98. 98.
    Wolkenstein, K.; Sun , H.; Falk, H.; Griesinger, C.: Structure and absolute configuration of Jurassic polyketide-derived spiroborate pigments obtained from microgram quantities. Journal of the American Chemical Society 137 (42), pp. 13460 - 13463 (2015)
  99. 99.
    Wysoczanski, P.; Becker, S.; Zweckstetter, M.: Structures of intermediates during RES complex assembly. Scientific Reports (2015)
 
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