Kai Tittmann
Max Planck Fellow, Professor at the University of Göttingen
Phone:+49 551 39-177811

Kai Tittmann

Molecular Enzymology

A central research topic of our department is the analysis of the molecular reaction mechanisms of enzymes (biocatalysts). In this context, we study enzymes with vitamin-derived cofactors, with metal ions, and Schiff base-forming enzymes. A particular focus is laid on the structural and kinetic characterization of reaction intermediates by high-resolution X-ray crystallography, steady-state and transient kinetic methods, NMR spectroscopy and theoretical studies. Knowledge about the reaction mechanism is exploited to redesign enzymes for biocatalytic applications and for drug design.

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