Genes and Behavior
The Department of Genes and Behavior investigates the dynamic interplay between gene expression, development and behavior in the mouse. Recently we developed efficient methods to detect, visualize, archive and mine spatial gene expression patterns in mammalian tissues at the mRNA level (www.genepaint.org). These data provide a powerful starting point to address the genetic regulatory network. Research focusing on mammalian brain development attempts to establish hierarchies in signaling cascades while our chronobiology studies are directed at the discovery and elucidation of novel pathways by which genes control circadian behavior at an organismal level.