Publications Biomedical Nuclear Magnetic Resonance GmbH
2010
Watanabe, T., J. Frahm and T. Michaelis:
Myelin mapping in the living mouse brain using manganese-enhanced magnetization transfer MRI.
NeuroImage 49, 1200-1204 (2010)
Zhang, S., K. T. Block and J. Frahm:
Magnetic resonance imaging in real time: Advances using radial FLASH.
Journal of Magnetic Resonance Imaging 31, 101-109 (2010)
2009
Auer, T., S. Pinter, N. Kovacs, Z. Kalmar, F. Nagy, R. A. Horvarth, B. Koszo, G. Kotek, G. Perlaki, M. Koves, B. Kalman, S. Komoly, A. Schwarcz, F. G. Woermann and J. Janszky:
Does obstetric brachial plexus injury influence speech dominance?
Annals of Neurology 65, 57-66 (2009)
Block, K. T., M. Uecker and J. Frahm:
Model-based iterative reconstruction for radial fast spin-echo MRI.
IEEE Transactions on Medical Imaging 28, 1759-1769 (2009)
Boretius, S., T. Michaelis, R. Tammer, R. Ashery-Padan, J. Frahm and A. Stoykova:
In vivo MRI of altered brain anatomy and fiber connectivity in adult Pax6 deficient mice.
Cerebral Cortex 19, 2838-2847 (2009)
Boretius, S., L. Kasper, R. Tammer, T. Michaelis and J. Frahm:
MRI of cellular layers in mouse brain in vivo.
NeuroImage 47, 1252-1260 (2009)
Dreha-Kulaczewski, S., G. Helms, P. Dechent, S. Hofer, J. Gaertner and J. Frahm:
Serial proton MR spectroscopy and diffusion tensor imaging in infantile Balo’s concentric sclerosis.
Neuroradiology 51, 113-121 (2009)
D´Souza, D. V.:
An fMRI study of chromatic processing in humans.
Spatial and temporal characteristics of the cortical visual areas.
Universität Göttingen, Göttingen (2009)
Gadjanski, I., S. K. Williams, S. Boretius, P. Lingor, J. Knoeferle, M. B. Saettler, R. Fairless, S. Hohmeister, K. W. Suehs, T. Michaelis, J. Frahm, M. K. Storch, M. Baehr and R. Diem:
Role of N-type voltage-dependent calcium channels in autoimmune optic neuritis.
Annals of Neurology 66, 81-93 (2009)
Hofer, S. and J. Frahm:
Topographical organization of the pyramidal fiber system - Diffusion tensor MRI of the human and rhesus monkey brain.
Open Medical Imaging Journal 3, 6-14 (2009)
Kallenberg, K., H. C. Block, G. Helms, K. Jung, A. Wrede, J. H. Buhk, A. Giese, J. Frahm, H. Strik, P. Dechent and M. Knauth:
Untreated glioblastoma multiforme: Increased myo-inositol and glutamine levels in the contralateral cerebral hemisphere at proton MR spectroscopy.
Radiology 253, 805-812 (2009)
Karaus, A., S. Hofer and J. Frahm:
Separation of fiber tracts within the human cingulum bundle using single-shot STEAM DTI.
Open Medical Imaging Journal 3, 21-27 (2009)
Kovacs, N., T. Auer, I. Balas, K. Karadi, K. Zambo, A. Schwarcz, P. Klivenyi, H. Jokeit, K. Horvarth, F. Nagy and J. Janszky:
Neuroimaging and cognitive changes during deja vu.
Epilepsy and Behavior 14, 190-196 (2009)
Luetcke, H., H. Gevensleben, B. Albrecht and J. Frahm:
Brain networks involved in early versus late response anticipation and their relation to conflict processing.
Journal of Cognitive Neuroscience 21, 2172-2184 (2009)
Michaelis, T., S. Boretius and J. Frahm:
Localized proton MRS of animal brain in vivo: models of human disorders.
Progress in Nuclear Magnetic Resonance Spectroscopy 55, 1-34 (2009)
Michaelis, T., A. Abaei, S. Boretius, R. Tammer, J. Frahm and C. Schlumbohm:
Intrauterine hyperexposure to dexamethasone of the common marmoset monkey revealed normal cerebral metabolite concentrations in adulthood as assessed by quantitative proton magnetic resonance spectroscopy in vivo.
Journal of Medical Primatology 38, 213-218 (2009)
Miro, X., X. Zhou, S. Boretius, T. Michaelis, C. Kubisch, G. Alvarez-Bolado and P. Gruss:
Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube.
Disease Models and Mechanisms 2, 412-418 (2009)
Radyushkin, K., K. Hammerschmidt, S. Boretius, F. Varoqueaux, A. El-Kordi, A. Ronnenberg, D. Winter, J. Frahm, J. Fischer and N. Brose:
Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit.
Genes, Brain and Behavior 8, 416-425 (2009)
Tammer, R., S. Hofer, K. D. Merboldt and J. Frahm:
Magnetic resonance imaging of the rhesus monkey brain.
Vandenhoeck und Ruprecht, Göttingen (2009) 263 pp.
Uecker, M., A. Karaus and J. Frahm:
Inverse reconstruction method for segmented multi-shot diffusion-weighted MRI with multiple coils.
Magnetic Resonance in Medicine 62, 1342-1348 (2009)
Uecker, M.:
Nonlinear reconstruction methods for parallel magnetic resonance imaging.
von Lewinski, F., S. Hofer, J. Kaus, K. D. Merboldt, H. Rothkegel, R. Schweizer, J. Frahm and W. Paulus:
Efficacy of EMG-triggered electrical arm stimulation in chronic hemiparetic stroke patients.
Restorative Neurology and Neuroscience 27, 189-197 (2009)
Wozny, C., J. Breustedt, F. Wolk, F. Varoqueaux, S. Boretius, A. R. Zivkovic, A. Neeb, J. Frahm, D. Schmitz and N. Brose:
The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.
Journal of Cell Science 122, 735-744 (2009)
Zhang, S.:
Real-time magnetic resonance imaging.
Universität Göttingen, Göttingen (2009)
2008
Auer, T., A. Schwarcz, T. Doczi, K. D. Merboldt and J. Frahm:
A novel group analysis for functional MRI of the human brain based on a two-threshold correlation (TTC) method.
Journal of Neuroscience Methods 167, 335-339 (2008)
Bartels, C., N. Mertens, S. Hofer, K. D. Merboldt, J. Dietrich, J. Frahm and H. Ehrenreich:
Callosal dysfunction in amyotrophic lateral sclerosis correlates with diffusion tensor imaging of the central motor system.
Neuromuscular Disorders 18, 398-407 (2008)
Block, K. T.:
Advanced methods for radial data sampling in magnetic resonance imaging.
Universität Göttingen, Göttingen (2008)
Block, T. and J. Frahm:
Radial single-shot STEAM MRI.
Magnetic Resonance in Medicine 59, 686-691 (2008)
Block, K. T., M. Uecker and J. Frahm:
Suppression of MRI truncation artifacts using total variation constrained data extrapolation.
International Journal of Biomedical Imaging DOI: 10.1155/2008/184123 (2008)
Boretius, S., I. Gadjanski, I. Demmer, M. Baehr, R. Diem, T. Michaelis and J. Frahm:
MRI of optic neuritis in a rat model.
NeuroImage 41, 323-334 (2008)
Brockmann, K., S. Dreha-Kulaczewski, P. Dechent, C. Bonnemann, G. Helms, M. Kyllermann, W. Brueck, J. Frahm, K. Huehne, J. Gaertner and B. Rautenstrauss:
Cerebral involvement in axonal Charcot-Marie-Tooth neuropathy caused by mitofusin2 mutations.
Journal of Neurology 255, 1049-1058 (2008)
Diem, R., I. Demmer, S. Boretius, D. Merkler, B. Schmelting, S. K. Williams, M. B. Saettler, M. Baehr, T. Michaelis, J. Frahm, W. Brueck and E. Fuchs:
Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology.
Investigative Opthalmology and Visual Science 49, 3707-3714 (2008)
Dreha-Kulaczewski, S. F., P. Dechent, J. Finsterbusch, K. Brockmann, J. Gaertner, J. Frahm and V. Hanefeld:
Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study.
Pediatric Research 63, 444-449 (2008)
Escher, A., S. Nessler, P. Vollmar, D. Merkler, S. Boretius, W. Brueck, H. Reichardt, F. Luehder and C. Stadelmann: Immunization of cuprizone-treated mice leads to cerebral inflammatory pathology. In: Acta Neuropathalogica, 116, 3, (2008) 342
Frahm, J., J. Baudewig, K. Kallenberg, A. Kastrup, K. D. Merboldt and P. Dechent:
The post-stimulation undershoot in BOLD fMRI of human brain is not caused by elevated cerebral blood volume.
NeuroImage 40, 473-481 (2008)
Frahm, J.:
Magnetresonanz-Tomografie in der Neurobiologie - von Maus zu Mensch.
In: Jahrbuch der Max-Planck-Gesellschaft 2007, Vandenhoeck und Ruprecht, Göttingen (2008) 87-91
Frahm, J.:
Robert Brown, Albert Einstein und der weiße Balken.
In: Jahrbuch der Akademie der Wissenschaften zu Göttingen 2007, de Gryter, Berlin (2008) 137-148
Hofer, S., K. D. Merboldt, R. Tammer and J. Frahm:
Rhesus monkey and human share a similar topography of the corpus callosum as revealed by diffusion tensor MRI in vivo.
Cerebral Cortex 18, 1079-1084 (2008)
Hofer, S. and J. Frahm:
In vivo mapping of fiber pathways in the Rhesus monkey brain.
The Open Medical Imaging Journal 2, 32-41 (2008)
Jamain, S., K. Radyushkin, K. Hammerschmidt, S. Granon, S. Boretius, F. Varoqueaux, N. Ramanantsoa, J. Gallego, A. Ronnenberg, D. Winter, J. Frahm, J. Fischer, T. Bourgeron, H. Ehrenreich and N. Brose:
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.
Proceedings of the National Academy of Sciences of the United States of America 105, 1710-1715 (2008)
Kern, T. A., H. Roerup, R. Werthschutzky and R. Tammer:
A remotely controlled lightweight MRI compatible ultrasonic actuator for micrometer positioning of electrodes during neuroethological primate research.
Lateralized anterior cingulate function during error processing and conflict monitoring as revealed by high-resolution fMRI.
Cerebral Cortex 18, 508-515 (2008)
Michael-Titus, A. T., M. Albert, G. J. Michael, T. Michaelis, T. Watanabe, J. Frahm, O. Pudovkina, M. G. C. van der Hart, M. B. Hesselink, E. Fuchs and B. Czeh:
SONU20176289, a compound combining partial dopamine D2 receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression.
European Journal of Pharmacology 598, 43-50 (2008)
Schwarcz, A., T. Auer, J. Janszky, T. Doczi, K. D. Merboldt and J. Frahm:
TTC post-processing is beneficial for functional MRI at low magnetic field: a comparative study at 1 T and 3 T.
European Radiology 18, 2594-2600 (2008)
Schweizer, R., D. Voit and J. Frahm:
Finger representations in human primary somatosensory cortex as revealed by high-resolution functional MRI of tactile stimulation.
NeuroImage 42, 28-35 (2008)
Uecker, M., T. Hohage, T. Block and J. Frahm:
Image reconstruction by regularized nonlinear inversion - Joint estimation of coil sensitivities and image content.
Magnetic Resonance in Medicine 60, 674-682 (2008)
Watanabe, T., J. Frahm and T. Michaelis:
Manganese-enhanced MRI of the mouse auditory pathway.
Magnetic Resonance in Medicine 60, 210-212 (2008)
Wilken, B., P. Dechent, F. Hanefeld and J. Frahm:
Proton MRS of a child with Sandhoff disease reveals elevated brain hexosamine.
European Journal of Paediatric Neurology 12, 56-60 (2008)
2007
Block, K. T., M. Uecker and J. Frahm:
Undersampled radial MRI with multiple coils. Iterative image reconstruction using a total variation constraint.
Magnetic Resonance in Medicine 57, 1086-1098 (2007)
Boretius, S., J. Wuerfel, F. Zipp, J. Frahm and T. Michaelis:
High-field diffusion tensor imaging of mouse brain in vivo using single-shot STEAM MRI.
Journal of Neuroscience Methods 161, 112-117 (2007)
Brockmann, K., P. Dechent, C. Boennemann, G. Schreiber, J. Frahm and F. Hanefeld:
Quantitative proton MRS of cerebral metabolites in laminin α2 chain deficiency.
Brain & Development 29, 357-364 (2007)
Frahm, J.:
Der schöne Schein der Magnetresonanz-Tomografie des Gehirns. Bilder des Unsichtbaren als Modelle der Wirklichkeit.
In: Bilderwelten. Vom farbigen Abglanz der Natur., (Ed.) Elsner, N., Wallstein, Göttingen (2007) 191-208
Karaus, A., K. D. Merboldt, J. Graessner and J. Frahm:
Black-blood imaging of the human heart using rapid stimulated echo acquisition mode (STEAM) MRI.
Journal of Magnetic Resonance Imaging 26, 1666-1671 (2007)
Kassmann, C. M., C. Lappe-Siefke, M. Baes, B. Bruegger, A. Mildner, H. B. Werner, O. Natt, T. Michaelis, M. Prinz, J. Frahm and K. A. Nave:
Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.
Nature Genetics 39, 969-976 (2007)
Luetcke, H.:
The role of human medial frontal cortex in cognition investigated by functional magnetic resonance imaging.
Universität Göttingen, Göttingen (2007)
Nessler, S., S. Boretius, C. Stadelmann, A. Bittner, D. Merkler, H. P. Hartung, T. Michaelis, W. Brueck, J. Frahm, N. Sommer and B. Hemmer:
Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage.
Brain 130, 2186-2198 (2007)
2006
Bohm, D., K. Hoffmann, F. Laccone, B. Wilken, P. Dechent, J. Frahm, I. Bartels and S. K. Bohlander:
Association of Jacobsen syndrome and bipolar affective disorder in a patient with a de Novo 11q terminal deletion.
American Journal of Medical Genetics Part A 140 A, 378-382 (2006)
Boretius, S., B. Schmelting, T. Watanabe, D. Merkler, R. Tammer, B. Czeh, T. Michaelis, J. Frahm and E. Fuchs:
Monitoring of EAE onset and progression in the common marmoset monkey by sequential high-resolution 3D MRI.
NMR in Biomedicine 19, 41-49 (2006)
Dreha-Kulaczewski, S., P. Dechent, G. Helms, J. Frahm, J. Gaertner and K. Brockmann:
Cerebral metabolic and structural alterations in hereditary spastic paraplegia with thin corpus callosum assessed by MRS and DTI.
Neuroradiology 48, 893-898 (2006)
Finsterbusch, J., J. Frahm and M. Koch:
Gradient and stimulated echo (GRASTE) imaging.
Magnetic Resonancein Medicine 55, 455-459 (2006)
Frahm, J., O. Natt, T. Watanabe, S. Boretius and T. Michaelis: Magnetic resonance imaging of animal brain in vivo.
Frahm, J., S. Boretius, T. Watanabe and T. Michaelis:
Magnetic resonance imaging of animal brain in vivo.
Alternativen zu Tierexperimenten 23, 78-82 (2006)
Frahm, J.:
Vom Kernmoment zum Gedankenblitz. Magnetresonanz-Tomografie des Gehirns.
In: Jahrbuch der Akademie der Wissenschaften zu Göttingen 2005, Vandenhoeck und Ruprecht, Göttingen (2006) 288-293
Gadjanski, I., S. Boretius, T. Michaelis, J. Frahm, M. Baehr and R. Diem: Upregulated expression of N-type voltage dependent calcium channels (Cav2.2) in autoimmune optic neuritis detected by magnetic resonance imaging and immunochemistry. In: Multiple Sclerosis, 12, Suppl. 1, (2006) S9
Groeschel, S., K. Brockmann, P. Dechent, E. Wilichowski, J. Frahm and F. Hanefeld:
Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces.
Pediatric Neurology 34, 35-40 (2006)
Henning, S., K. D. Merboldt and J. Frahm:
Task- and EEG-correlated analyses of BOLD MRI responses to eyes opening and closing.
Brain Research 1073, 359-364 (2006)
Hofer, S. and J. Frahm:
Topography of the human corpus callosum revisited - Comprehensive fiber tractography using diffusion tensor magnetic resonance imaging.
NeuroImage 32, 989-994 (2006)
Luetcke, H.:
Parcellating the medial frontal cortex: Evaluative and cognitive components of performance monitoring.
Journal of Neuroscience 26, 7129-7130 (2006)
Luetcke, H., K. D. Merboldt and J. Frahm:
The cost of parallel imaging in functional MRI of the human brain.
Magnetic Resonance Imaging 24, 1-5 (2006)
Nessler, S. A., S. Boretius, C. Stadelmann, A. Bittner, D. Merkler, H. P. Hartung, T. Michaelis, W. Bruck, J. Frahm, N. Sommer and B. Hemmer: MRI correlates of lesion pathology in T-cell clone mediated mouse experimental autoimmune encephalomyelitis. In: Journal of Neuroimmunology, 178, Suppl. 1, (2006) 157
Siren, A. L., K. Radyushkin, S. Boretius, D. Kaemmer, C. C. Riechers, O. Natt, D. Sargin, T. Watanabe, S. Sperling, T. Michaelis, J. Price, B. Meyer, J. Frahm and H. Ehrenreich:
Global brain atrophy after unilateral parietal lesion and its prevention by erythropoetin.
Brain 129, 480-489 (2006)
Tammer, R., L. Ehrenreich, S. Boretius, T. Watanabe, J. Frahm and T. Michaelis:
Compatibility of glass-guided recording microelectrodes in the brain stem of squirrel monkeys with high-resolution 3D MRI.
Journal of Neuroscience Methods 153, 221-229 (2006)
Watanabe, T., J. Schachtner, M. Krizan, S. Boretius, J. Frahm and T. Michaelis:
Manganese-enhanced 3D MRI of established and disrupted synaptic activity in the developing insect brain in vivo.
Journal of Neuroscience Methods 158, 50-55 (2006)
Watanabe, T., R. Tammer, S. Boretius, J. Frahm and T. Michaelis:
Chromium(VI) as a novel MRI contrast agent for cerebral white matter: Preliminary results in mouse brain in vivo.
Magnetic Resonance in Medicine 56, 1-6 (2006)
Watanabe, T., J. Radulovic, S. Boretius, J. Frahm and T. Michaelis:
Mapping of the habenulo-interpeduncular pathway in living mice using manganese-enhanced 3D MRI.
Magnetic Resonance Imaging 24, 209-215 (2006)
2005
Bestmann, S., J. Baudewig, H. R. Siebner, J. C. Rothwell and J. Frahm:
BOLD MRI responses to repetitive TMS over human dorsal premotor cortex.
NeuroImage 28, 22-29 (2005)
Block, K. T. and J. Frahm:
Spiral imaging: A critical appraisal.
Journal of Magnetic Resonance Imaging 21, 657-668 (2005)
Czeh, B., O. Pudovkina, M. G. C. van der Hart, M. Simon, U. Heilbronner, T. Michaelis, T. Watanabe, J. Frahm and E. Fuchs:
Examining SLV-323, a novel NK1 receptor antagonist, in a chronic psychosocial stress model for depression.
Psychopharmacology 180, 548-557 (2005)
Fuchs, E., B. Czeh, P. J. Lucassen, B. S. McEwen, T. Michaelis, S. Chattarji, R. Descomps and A. M. Magarinos: Preclinical studies with tianeptine reinforce the neuroplasticity approach to the pathophysiology of major depression. In: Biological Psychiatry, 57, 8 Suppl. S, (2005) 173S
Hanefeld, F., K. Brockmann, P. J. W. Pouwels, B. Wilken, J. Frahm and P. Dechent:
Quantitative proton MRS of Pelizaeus-Merzbacher disease - Evidence of dys- and hypomyelination.
Neurology 65, 701-706 (2005)
Henning, S., K. D. Merboldt and J. Frahm:
Simultaneous recordings of visual evoked potentials and BOLD MRI activations in response to visual motion processing.
NMR in Biomedicine 18, 543-552 (2005)
Henning, S., F. Tergau and J. Frahm: Mapping of interictal epileptic discharges: Comparison of results from event-related BOLD MRI and dipole source analysis. In: Epilepsia, 46, Suppl. 6, (2005) 333-334
Merkler, D., S. Boretius, C. Stadelmann, T. Ernsting, T. Michaelis, J. Frahm and W. Brueck:
Multicontrast MRI of remyelination in the central nervous system.
NMR in Biomedicine 18, 395-403 (2005)
Michaelis, T., T. Watanabe, O. Natt, S. Boretius, J. Frahm, S. Utz and J. Schachtner:
In vivo 3D MRI of insect brain: cerebral development during metamorphosis of Manduca sexta.
NeuroImage 24, 596-602 (2005)
Michaelis, T. and J. Frahm:
Low-field vs. high-field proton MRS of mouse brain in vivo.
Magnetic Resonance in Medicine 54, 1046-1047 (2005)
Natt, O. and J. Frahm:
In vivo magnetic resonance imaging: insights into structure and function of the central nervous system.
Measurement Science and Technology 16, R17-R36 (2005)
Natt, O., V. Bezkorovaynyy, T. Michaelis and J. Frahm:
Use of phased array coils for a determination of absolute metabolite concentrations.
Magnetic Resonance in Medicine 53, 3-8 (2005)
Rieseberg, S., K. D. Merboldt, M. Kuntzel and J. Frahm:
Diffusion tensor imaging using partial Fourier STEAM MRI with projection onto convex subsets reconstruction.
Magnetic Resonance in Medicine 54, 486-490 (2005)
Tschopp, O., Z. Z. Yang, D. Brodbeck, B. A. Dummler, M. Hemmings-Mieszczak, T. Watanabe, T. Michaelis, J. Frahm and B. A. Hemmings:
Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis.
Development 132, 2943-2954 (2005)
Voit, D. and J. Frahm:
Echo train shifted multi-echo FLASH for functional MRI of the human brain at ultra-high spatial resolution.
NMR in Biomedicine 18, 481-488 (2005)
2004
Bestmann, S., J. Baudewig, H. R. Siebner, J. C. Rothwell and J. Frahm:
Functional MRI of the immediate impact of transcranial magnetic stimulation on cortical and subcortical motor circuits.
European Journal of Neuroscience 19, 1950-1962 (2004)
Boretius, S., O. Natt, T. Watanabe, R. Tammer, L. Ehrenreich, J. Frahm and T. Michaelis:
In vivo diffusion tensor mapping of the brain of squirrel monkey, rat, and mouse using single-shot STEAM MRI.
Magnetic Resonance Materials in Physics Biology and Medicine 17, 339-347 (2004)
Brockmann, K., J. Finsterbusch, U. Schara, E. Wilichowski, J. Frahm and F. Hanefeld:
Stroke-like pattern in DTI and MRS of childhood mitochondrial leukoencephalopathy.
Neuroradiology 46, 267-271 (2004)
Dechent, P., K. D. Merboldt and J. Frahm: Is the human primary motor cortex involved in motor imagery? (vol 19, pg 138, 2004). Elsevier, (2004)
Dechent, P., K. D. Merboldt and J. Frahm:
Is the human primary motor cortex involved in motor imagery?
Cognitive Brain Research 19, 138-144 (2004)
Dechent, P. and J. Frahm:
Funktionelle Magnetresonanz. Tomografie des menschlichen Gehirns.
Neuroforum Bd 10, 229-236 (2004)
Frahm, J., P. Dechent, J. Baudewig and K. D. Merboldt:
Advances in functional MRI of the human brain.
Progress in Nuclear Magnetic Resonance Spectroscopy 44, 1-32 (2004)
Fuchs, E., B. Czeh, M. H. P. Kole, T. Michaelis and P. J. Lucassen:
Alterations of neuroplasticity in depression: the hippocampus and beyond.
European Neuropsychopharmacology 14, S481-S490 (2004)
Fuchs, E., B. Czeh, T. Michaelis, P. J. Lucassen and M. H. P. Kole: Alterations of neuroplasticity in depression: The hippocampus and beyond. In: International Journal of Neuropsychopharmacology, 7, Suppl. 1, (2004) S101
Fuchs, E., B. Czeh, T. Michaelis, P. J. Lucassen, B. S. McEwen and A. M. Magarinos: Preclinical studies with tianeptine support new theories on the pathophysiology of major depression. In: International Journal of Neuropsychopharmacology, 7, Suppl. 1, (2004) S187
Watanabe, T., J. Frahm and T. Michaelis:
Functional mapping of neural pathways in rodent brain in vivo using manganese-enhanced three-dimensional magnetic resonance imaging.
NMR in Biomedicine 17, 554-568 (2004)
Watanabe, T., J. Radulovic, J. Spiess, O. Natt, S. Boretius, J. Frahm and T. Michaelis:
In vivo 3D MRI staining of the mouse hippocampal system using intracerebral injection of MnCl2.
NeuroImage 22, 860-867 (2004)
2003
Baudewig, J., P. Dechent, K. D. Merboldt and J. Frahm:
Thresholding in correlation analyses of magnetic resonance functional neuroimaging.
Magnetic Resonance Imaging 21, 1121-1130 (2003)
Bestmann, S., J. Baudewig, H. R. Siebner, J. C. Rothwell and J. Frahm:
Subthreshold high-frequency TMS of human primary motor cortex modulates interconnected frontal motor areas as detected by interleaved fMRI-TMS.
NeuroImage 20, 1685-1696 (2003)
Bestmann, S., J. Baudewig and J. Frahm:
On the synchronization of transcranial magnetic stimulation and functional echo-planar imaging.
Journal of Magnetic Resonance Imaging 17, 309-316 (2003)
Brockmann, K., P. Dechent, B. Wilken, O. Rusch, J. Frahm and F. Hanefeld:
Proton MRS profile of cerebral metabolic abnormalities in Krabbe disease.
Neurology 60, 819-825 (2003)
Brockmann, K., P. Dechent, M. Meins, M. Haupt, J. Sperner, U. Stephani, J. Frahm and F. Hanefeld:
Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
Journal of Neurology 250, 300-306 (2003)
Brockmann, K., J. Finsterbusch, B. Terwey, J. Frahm and F. Hanefeld:
Megalencephalic leukoencephalopathy with subcortical cysts in an adult: quantitative proton MR spectroscopy and diffusion tensor MRI.
Neuroradiology 45, 137-142 (2003)
Brockmann, K., P. J. W. Pouwels, P. Dechent, K. M. Flanigan, J. Frahm and F. Hanefeld:
Cerebral proton magnetic resonance spectroscopy of a patient with giant axonal neuropathy.
Brain & Development 25, 45-50 (2003)
Dechent, P. and J. Frahm:
Characterization of the human visual V6 complex by functional magnetic resonance imaging.
European Journal of Neuroscience 17, 2201-2211 (2003)
Dechent, P. and J. Frahm:
Functional somatotopy of finger representations in human primary motor cortex.
Human Brain Mapping 18, 272-283 (2003)
Haenicke, W. and H. U. Vogel:
An analytical solution for the SSFP signal in MRI.
Magnetic Resonance in Medicine 49, 771-775 (2003)
Jacob, S., J. Finsterbusch, J. H. Weishaupt, D. Khorram-Sefat, J. Frahm and H. Ehrenreich:
Diffusion tensor imaging for long-term follow-up of corticospinal tract degeneration in amyotrophic lateral sclerosis.
Neuroradiology 45, 598-600 (2003)
Liebetanz, D., S. Fauser, T. Michaelis, B. Czeh, T. Watanabe, W. Paulus, J. Frahm and E. Fuchs:
Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain.
Journal of Psychiatric Research 37, 277-286 (2003)
Natt, O., T. Watanabe, S. Boretius, J. Frahm and T. Michaelis:
Magnetization transfer MRI of mouse brain reveals areas of high neural density.
Magnetic Resonance Imaging 21, 1113-1120 (2003)
Schwarcz, A., O. Natt, T. Watanabe, S. Boretius, J. Frahm and T. Michaelis:
Localized proton MRS of cerebral metabolite profiles in different mouse strains.
Magnetic Resonance in Medicine 49, 822-827 (2003)
Siebner, H. R., L. Lee and S. Bestmann:
Interleaving TMS with functional MRI: now that it is technically feasible how should it be used?
Clinical Neurophysiology 114, 1997-1999 (2003)
Wilken, B., P. Dechent, K. Brockmann, J. Finsterbusch, M. Baumann, W. Ebell, G. C. Korenke, P. J. W. Pouwels, F. Hanefeld and J. Frahm:
Quantitative proton magnetic resonance spectroscopy of children with adrenoleukodystrophy before and after hematopoietic stem cell transplantation.
Neuropediatrics 34, 237-246 (2003)
2002
Brockmann, K., A. Bjornstad, P. Dechent, G. C. Korenke, J. Smeitink, J. M. F. Trijbels, S. Athanassopoulos, R. Villagran, O. H. Skjeldal, E. Wilichowski, J. Frahm and F. Hanefeld:
Succinate in dystrophic white matter: A proton magnetic resonance spectroscopy finding characteristic for complex II deficiency.
Annals of Neurology 52, 38-46 (2002)
Byun, W. M., S. O. Shin, Y. M. Chang, S. J. Lee, J. Finsterbusch and J. Frahm:
Diffusion-weighted MR imaging of metastatic disease of the spine: Assessment of response to therapy.
American Journal of Neuroradiology 23, 906-912 (2002)
Finsterbusch, J. and J. Frahm:
Half-Fourier single-shot STEAM MRI.
Magnetic Resonance in Medicine 47, 611-615 (2002)
Fransson, P., K. D. Merboldt, K. M. Petersson, M. Ingvar and J. Frahm:
On the effects of spatial filtering - A comparative fMRI study of episodic memory encoding at high and low resolution.
NeuroImage 16, 977-984 (2002)
Fuchs, E., B. Czeh, T. Michaelis, G. de Biurrun, T. Watanabe and J. Frahm:
Synaptic plasticity and tianeptine: structural regulation.
European Psychiatry 17, 311S-317S (2002)
Koch, M., V. Glauche, J. Finsterbusch, U. Nolte, J. Frahm, C. Weiller and C. Buechel:
Distortion-Free Diffusion Tensor Imaging of Cranial Nerves and of Inferior Temporal and Orbitofrontal White Matter.
NeuroImage 17, 497-506 (2002)
Merboldt, K. D., J. Baudewig, S. Treue and J. Frahm:
Functional MRI of self-controlled stereoscopic depth perception.
NeuroReport 13, 1721-1725 (2002)
Natt, O., T. Watanabe, S. Boretius, J. Radulovic, J. Frahm and T. Michaelis:
High-resolution 3D MRI of mouse brain reveals small cerebral structures in vivo.
Journal of Neuroscience Methods 120, 203-209 (2002)
Rieseberg, S., J. Frahm and F. Finsterbusch:
Two-dimensional spatially-selective RF excitation pulses in echo-planar Imaging.
Magnetic Resonance in Medicine 47, 1186-1193 (2002)
van der Hart, M. G. C., B. Czeh, G. de Biurrun, T. Michaelis, T. Watanabe, O. Natt, J. Frahm and E. Fuchs:
Substance P Receptor Antagonist and Clomipramine Prevent Stress-Induced Alterations in Cerebral Metabolites, Cytogenesis in the Dentate Gyrus and Hippocampal Volume.
Molecular Psychiatry 7, 933-941 (2002)
Watanabe, T., O. Natt, S. Boretius, J. Frahm and T. Michaelis:
In vivo 3D MRI staining of mouse brain after subcutaneous application of MnCl2.
Magnetic Resonance in Medicine 48, 852-859 (2002)
2001
Baudewig, J.:
Kombination der neurofunktionellen Magnetresonanz-Tomografie mit neurophysiologischen Methoden (EEG, TMS und tDCS).
Göttingen, (2001)
Baudewig, J., H. J. Bittermann, W. Paulus and J. Frahm:
Simultaneous EEG and functional MRI of epileptic activity: A Case Report.
Clinical Neurophysiology 112, 1196-1200 (2001)
Baudewig, J., M. A. Nitsche, W. Paulus and J. Frahm:
Regional modulation of BOLD MRI responses to human sensorimotor activation by transcranial direct current stimulation.
Magnetic Resonance in Medicine 45, 196-201 (2001)
Baudewig, J., H. R. Siebner, S. Bestmann, F. Tergau, T. Tings, W. Paulus and J. Frahm:
Functional MRI of cortical activations induced by transcranial magnetic stimulation (TMS).
NeuroReport 12, 3543-3548 (2001)
Baye, I.:
Synchronisation der funktionellen Magnetresonanz-Tomografie des Gehirns mit peripheren Komponenten zur Stimulation und Aufzeichnung von Hirnaktivitäten.
FH Hildesheim/Holzminden/Göttingen, (2001)
Bruhn, H.:
Untersuchungen physiologischer und pathophysiologischer Stoffwechselzustände und Hirnfunktionen des Menschen mit Hilfe neuer methodischer Entwicklungen zur ortsaufgelösten Magentresonanz-Spektroskopie und funcktionellen Magnetresonanz-Tomografie.
HU Berlin, (2001)
Bruhn, H., P. Fransson and J. Frahm:
Modulation of cerebral blood oxygenation by indomethacin. MR imaging at rest and functional brain activation.
Journal of Magnetic Resonance Imaging 13, 325-334 (2001)
Czeh, B., T. Michaelis, T. Watanabe, J. Frahm, G. de Biurrun, M. van Kampen, A. Bartolomucci and E. Fuchs:
Stress-induced changes in cerebral metabolites, hippocampal volume and cell proliferation are prevented by antidepressant treatment with tianeptine.
Proceedings of the National Academy of Sciences USA 98, 12796-12801 (2001)
Dechent, P.:
Entwicklung der funktionellen Magnetresonanz-Tomografie des Gehirns mit höchster räumlicher Auflösung.
Mainz, (2001)
Dorre, K., S. Brakmann, T. Winkler, T. Wetzel, M. Lapczyna, M. Stuke, B. Angerer, W. Ankenbauer, Z. Foldes-Papp, R. Rigler and M. Eigen:
Towards a general procedure for sequencing single DNA molecules.
Journal of Biotechnology 86, 255-267 (2001)
Fransson, P., K. D. Merboldt, M. Ingvar, K. M. Petersson and J. Frahm:
Functional MRI with reduced susceptibility artifact: High-resolution mapping of episodic memory encoding.
NeuroReport 12, 1415-1420 (2001)
Kuhlmann, T., A. Schroeter, P. Dechent, F. Weber, H. H. Rustenbeck, L. Fuezesi, W. Brueck, H. Ehrenreich and J. Frahm:
Diagnosis of a multifocal B cell lymphoma with preceding demyelinating CNS lesions by single-voxel proton MR spectroscopy.
Journal of Neurology, Neurosurgery & Psychiatry 70, 259-262 (2001)
Merboldt, K. D., P. Fransson, H. Bruhn and J. Frahm:
Functional MRI of the human amygdala?
NeuroImage 14, 253-257 (2001)
Michaelis, T., G. de Biurrun, T. Watanabe, J. Frahm, F. Ohl and E. Fuchs:
Gender-specific alterations of cerebral metabolites with aging and cortisol treatment.
Journal of Psychiatric Research 35, 231-237 (2001)
Rieseberg, S.:
Zweidimensional-ortsselektive Hochfrequenz-Pulse in der Magnetresonanz-Tomographie.
Göttingen, (2001)
Watanabe, T., T. Michaelis and J. Frahm:
Mapping of retinal projections in the living rat using high-resolution 3 D MRI with Mn2+-induced contrast.
Magnetic Resonance in Medicine 46, 424-429 (2001)
2000
Baudewig, J., W. Paulus and J. Frahm:
Artifacts caused by transcranial magnetic stimulation coils and EEG electrodes in T 2-weighted echo-planar imaging.
Magnetic Resonance Imaging 18, 479-480 (2000)
Benaron, D. A., S. R. Hintz, A. Villringer, D. Boas and A. Kleinschmidt:
Noninvasive functional imaging of human brain using light.
Journal of Cerebral Blood Flow and Metabolism 20, 469-477 (2000)
Dechent, P. and J. Frahm:
Direct mapping of ocular dominance columns in human primary visual cortex.
NeuroReport 11, 3247-3249 (2000)
Frahm, J.:
Zur materiellen Organisation menschlichen Denkens: Magnetresonanz-Tomografie des Gehirns.
Wallstein Verlag, Göttingen (2000)
Finsterbusch, J. and J. Frahm:
Diffusion tensor mapping of the human brain using single-shot line scan imaging.
Journal of Magnetic Resonance Imaging 12, 388-394 (2000)
Finsterbusch, J. and J. Frahm:
Gradient-echo line scan imaging using 2 D-selective rf excitation.
Journal of Magnetic Resonance 147, 17-25 (2000)
Frahm, J.:
Mit Kilogauss ins menschliche Gehirn: Anatomie, Stoffwechsel und Funktion.
Mitteilungen der Gauss-Gesellschaft 37, 3-16 (2000)
Frahm, J. and F. Hanefeld:
Single voxel proton MR spectroscopy. Methods and applications in neuropediatrics.
Rivista di Neuroradiologia 13, 7-15 (2000)
Merboldt, K. D., J. Finsterbusch and J. Frahm:
Reducing inhomogeneity artifacts in functional MRI of human brain activation. - Thin sections vs gradient compensation.
Journal of Magnetic Resonance 145, 184-191 (2000)
Nolte, U., J. Finsterbusch and J. Frahm:
Rapid isotropic diffusion mapping without susceptibility artifacts. Whole brain studies using diffusion-weighted single-shot STEAM MR imaging.
Magnetic Resonance in Medicine 44, 731-736 (2000)
Stoppe, G., H. Bruhn, P. J. W. Pouwels, W. Haenicke and J. Frahm:
Alzheimer's disease: Absolute quantification of cerebral metabolites in vivo using localized proton magnetic resonance spectroscopy.
Alzheimer Disease and Associated Disorders 14, 112-119 (2000)
Wilken, B., P. Dechent, J. Herms, C. Maxton and E. Markakis:
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Pediatric Neurology 23, 22-31 (2000)
Frahm, J. and W. Haenicke:
Single voxel proton NMR. Human subjects.
Wiley, Chichester (2000)
1999
Bitsch, A., H. Bruhn, V. I. Vougioukas, A. K. Stringaris, H. Lassmann, J. Frahm and W. Brueck:
Inflammatory CNS demyelination: Histopathologic correlation with in vivo quantitative proton MR spectroscopy.
American Journal of Neuroradiology 20, 1619-1627 (1999)
Choi, C. G. and J. Frahm:
Localized proton MRS of the human hippocampus. Metabolite concentrations and relaxation times.
Magnetic Resonance in Medicine 41, 204-207 (1999)
Dechent, P., P. J. W. Pouwels and J. Frahm:
Neither short-term nor long-term administration of oral choline alters metabolite concentrations in human brain.
Biological Psychiatry 46, 406-411 (1999)
Dechent, P., P. J. W. Pouwels, B. Wilken, F. Hanefeld and J. Frahm:
Increase of total creatine in human brain after oral supplementation of creatine-monohydrate.
American Journal of Physiology 277, 698-704 (1999)
Finsterbusch, J.:
Linienselektive Bildgebungsverfahren in der Magnetresonanz-Tomografie.
Göttingen, (1999)
Finsterbusch, J. and J. Frahm:
Single-shot line scan imaging using stimulated echoes.
Journal of Magnetic Resonance 137, 144-153 (1999)
Finsterbusch, J. and J. Frahm:
Diffusion-weighted single-shot line scan imaging of the human brain.
Magnetic Resonance in Medicine 42, 772-778 (1999)
Frahm, J.:
Magnetic resonance functional neuroimaging: New insights into the human brain.
Current Science 76, 735-743 (1999)
Fransson, P.:
Analysis and development of strategies for magnetic resonance functional neuroimaging.
Stockholm, (1999)
Fransson, P., G. Krueger, K. D. Merboldt and J. Frahm:
Temporal and spatial MRI responses to subsecond visual activation.
Magnetic Resonance Imaging 17, 1-7 (1999)
Fransson, P., G. Krueger, K. D. Merboldt and J. Frahm:
MRI of functional deactivation. Temporal and spatial characteristics of oxygenation-sensitive responses in human visual cortex.
NeuroImage 9, 611-618 (1999)
Haenicke, W., J. Frahm and A. D. Wittmann:
Magnetresonanz-Tomografie des Gehirns von Carl Friedrich Gauss.
MPIBPC News 5, 1-4 (1999)
Helms, G. and J. Frahm:
Magnetization transfer attenuation of creatine resonances in localized proton MRS of human brain in vivo.
NMR in Biomedicine 12, 490-494 (1999)
Kleinschmidt, A., H. Bruhn, G. Krueger, K. D. Merboldt, G. Stoppe and J. Frahm:
Effects of sedation, stimulation, and placebo on cerebral blood oxygenation. A magnetic resonance neuroimaging study of psychotropic drug action.
NMR in Biomedicine 12, 286-292 (1999)
Krueger, G., P. Fransson, K. D. Merboldt and J. Frahm:
Does stimulus quality affect the physiologic MRI responses to brief visual activation?
NeuroReport 10, 1277-1281 (1999)
Michaelis, T., M. Wick, H. Fujimori, A. Matsumura and J. Frahm:
Proton MRS of oral creatine supplementation in rats. Cerebral metabolite concentrations and ischemic challenge.
NMR in Biomedicine 12, 309-314 (1999)
Nolte, U.:
Diffusionskodierende NMR-Tomografie des Gehirns.
Göttingen, (1999)
Ohl, F., T. Michaelis, H. Fujimori, J. Frahm, S. Rensing and E. Fuchs:
Volumetric MRI measurements of the tree shrew hippocampus.
Journal of Neuroscience Methods 88, 189-193 (1999)
Frahm, J.:
Magnetresonanz-Tomografie und Spektroskopie. Bemerkungen zu einer Entwicklung aus der Max-Planck-Gesellschaft.
Hirzel, Stuttgart (1999)
Pouwels, P. J. W., K. Brockmann, B. Kruse, B. Wilken, M. Wick, F. Hanefeld and J. Frahm:
Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS.
Pediatric Research 46, 474-485 (1999)
Wick, M.:
Methodische Weiterentwicklungen der lokalisierten 1H-NMR Spektroskopie zur Charakterisierung der transienten zerebralen Ischämie an der Ratte.
Göttingen, (1999)
Wick, M., T. Michaelis, H. Fujimori and J. Frahm:
Brain water diffusion in normal and creatine-supplemented rats during transient global ischemia.
Magnetic Resonance in Medicine 42, 798-802 (1999)
Wilichowski, E., P. J. W. Pouwels, J. Frahm and F. Hanefeld:
Quantitative proton magnetic resonance spectroscopy of cerebral metabolic disturbances in patients with MELAS.
Neuropediatrics 30, 256-263 (1999)
Frahm, J., P. Fransson and G. Krueger:
Magnetic resonance imaging of human brain function.
Springer, Berlin (1999)
Wittmann, A. D., J. Frahm and W. Haenicke:
Magnetresonanz-Tomografie des Gehirns von Carl Friedrich Gauss.
Mitteilungen der Gauss-Gesellschaft 36, 9-19 (1999)
1998
Fransson, P., G. Krueger, K. D. Merboldt and J. Frahm:
Temporal characteristics of oxygenation-sensitive MRI responses to visual activation in humans.
Magnetic Resonance in Medicine 39, 912-919 (1998)
Fransson, P., G. Krueger, K. D. Merboldt and J. Frahm:
Physiologic aspects of event related paradigms in magnetic resonance functional neuroimaging.
NeuroReport 9, 2001-2005 (1998)
Fujimori, H., T. Michaelis, M. Wick and J. Frahm:
Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain.
Magnetic Resonance in Medicine 39, 647-650 (1998)
Krueger, G., A. Kleinschmidt and J. Frahm:
Stimulus dependence of oxygenation-sensitive MRI responses to sustained visual activation.
NMR in Biomedicine 11, 75-79 (1998)
Kruse, B., P. J. W. Pouwels, H. J. Christen, J. Frahm and F. Hanefeld:
Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome.
Pediatric Neurology 18, 176-180 (1998)
Pouwels, P. J. W. and J. Frahm:
Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS.
Magnetic Resonance in Medicine 39, 53-60 (1998)
Pouwels, P. J. W., B. Kruse, G. C. Korenke, X. Mao, F. Hanefeld and J. Frahm:
Quantitative proton magnetic resonance spectroscopy of childhood adrenoleukodystrophy.
Neuropediatrics 29, 254-264 (1998)
Frahm, J. and W. Haenicke:
Rapid Scan Techniques.
Mosby, St. Louis (1998)
Stoerig, P., A. Kleinschmidt and J. Frahm:
No visual responses in denervated V1: High-resolution functional magnetic resonance imaging of a blindsight patient.
NeuroReport 9, 21-25 (1998)
1996
Frahm, J. and F. Hanefeld:
Localized proton magnetic resonance spectroscopy of cerebral metabolites.
Neuropediatrics 27, 64-69 (1996)
Kleinschmidt, A., B. B. Lee, M. Requardt and J. Frahm:
Functional mapping of color processing by magnetic resonance imaging of responses to selective P- and M-pathway stimulation.
Experimental Brain Research 110, 279-288 (1996)
Korenke, G. C., P. J. W. Pouwels, J. Frahm, D. H. Hunneman, S. Stoeckler, E. Krasemann, W. Jost and F. Hanefeld:
Arrested cerebral adrenoleukodystrophy: A clinical and proton magnetic resonance spectroscopy study in three patients.
Pediatric Neurology 15, 103-107 (1996)
Krueger, G., A. Kleinschmidt and J. Frahm:
Dynamic MRI sensitized to cerebral blood oxygenation and flow during sustained activation of human visual cortex.
Magnetic Resonance in Medicine 35, 797-800 (1996)
Michaelis, T., G. Helms and J. Frahm:
Metabolic alterations in brain autopsies: Proton NMR identification of free glycerol.
NMR in Biomedicine 9, 121-124 (1996)
Nitschke, M. F., A. Kleinschmidt, K. Wessel and J. Frahm:
Somatotopic motor representation in the human anterior cerebellum - A high-resolution functional MRI study.
Brain 119, 1023-1029 (1996)
Stockler, S., F. Hanefeld and J. Frahm:
Creatine replacement therapy in guanidinoacetate methyltransferase deficiency, a novel inborn error of metabolism.
Lancet 348, 789-790 (1996)
Wilken, B., G. Helms, H. J. Christen, J. Behnke, J. Frahm and F. Hanefeld:
Localized proton magnetic resonance spectroscopy of a cerebellar tumor in a two-year-old child.
Childs Nervous System 12, 626-629 (1996)
1995
Boecker, H., D. Khorram-Sefat, A. Kleinschmidt, K. D. Merboldt, W. Haenicke, M. Requardt and J. Frahm:
High-resolution functional magnetic resonance imaging of cortical activation during tactile exploration.
Human Brain Mapping 3, 236-244 (1995)
Frahm, J., K. D. Merboldt and W. Haenicke:
The effects of intravoxel dephasing and incomplete slice refocusing on susceptibility contrast in gradient-echo MRI.
Journal of Magnetic Resonance Series B 109, 234-237 (1995)
Hanefeld, F., B. Kruse, U. Holzbach, H. J. Christen, K. D. Merboldt, W. Haenicke and J. Frahm:
Hemimegalencephaly: Localized proton magnetic resonance spectroscopy in vivo.
Epilepsia 36, 1215-1224 (1995)
Hanefeld, F., H. J. Christen, U. Holzbach, B. Kruse, J. Frahm and W. Haenicke:
Cerebral proton magnetic-resonance spectroscopy in rett-syndrome.
Neuropediatrics 26, 126-127 (1995)
Holzbach, U., F. Hanefeld, G. Helms, W. Haenicke and J. Frahm:
Localized proton magnetic resonance spectroscopy of cerebral abnormalities in children with carbohydrate-deficient glycoprotein syndrome.
Acta Paediatrica 84, 781-786 (1995)
Kleinschmidt, A., W. Haenicke, M. Requardt, K. D. Merboldt and J. Frahm:
Data-analysis in brain activation studies with MRI.
Radiologe 35, 242-251 (1995)
Kleinschmidt, A., M. Requardt, K. D. Merboldt and J. Frahm:
On the use of temporal correlation coefficients for magnetic resonance mapping of functional brain activation: Individualized thresholds and spatial response delineation.
International Journal of Imaging Systems and Technology 6, 238-244 (1995)
Kleinschmidt, A., H. Steinmetz, M. Sitzer, K. D. Merboldt and J. Frahm:
Magnetic resonance imaging of regional cerebral blood oxygenation changes under acetazolamide in carotid occlusive disease.
Stroke 26, 106-110 (1995)
Merboldt, K. D., G. Krueger, W. Haenicke, A. Kleinschmidt and J. Frahm:
Functional mri of human brain activation combining high spatial and temporal resolution by a cine flash technique.
Magnetic Resonance in Medicine 34, 639-644 (1995)
Michaelis, T. and J. Frahm:
On the 3.35 ppm singlet resonance in proton NMR spectra of brain tissue: Scyllo-inositol or methanol contamination?
Magnetic Resonance in Medicine 34, 775-776 (1995)
Nagatomo, Y., M. Wick, F. Prielmeier and J. Frahm:
Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo.
NMR in Biomedicine 8, 265-270 (1995)
Wick, M., Y. Nagatomo, F. Prielmeier and J. Frahm:
Alteration of intracellular metabolite diffusion in rat-brain in-vivo during ischemia and reperfusion.
Stroke 26, 1930-1933 (1995)
1994
Boecker, H., A. Kleinschmidt, M. Requardt, W. Haenicke, K. D. Merboldt and J. Frahm:
Functional cooperativity of human cortical motor areas during self-paced simple finger movements a high-resolution MRI study.
Brain 117, 1231-1239 (1994)
Boecker, H., A. Kleinschmidt, A. Weindl, B. Conrad, W. Haenicke and J. Frahm:
Dysfunctional activation of subcortical nuclei in palatal myoclonus detected by high-resolution MRI.
NMR in Biomedicine 7, 327-329 (1994)
Bruhn, H., A. Kleinschmidt, H. Boecker, K. D. Merboldt, W. Haenicke and J. Frahm:
The effect of acetazolamide on regional cerebral blood oxygenation at rest and under stimulation as assessed by MRI.
Journal of Cerebral Blood Flow and Metabolism 14, 742-748 (1994)
Dixon, R. M. and J. Frahm:
Localized proton MR spectroscopy of the human kidney in vivo by means of short echo time STEAM sequences.
Magnetic Resonance in Medicine 31, 482-487 (1994)
Frahm, J., K. D. Merboldt, W. Haenicke, A. Kleinschmidt and H. Boecker:
Brain or vein-oxygenation or flow? On signal physiology in functional MRI of human brain activation.
NMR in Biomedicine 7, 45-53 (1994)
Frahm, J., K. D. Merboldt and W. Haenicke:
The influence of the slice-selection gradient on functional MRI of human brain activation.
Journal of Magnetic Resonance Series B 103, 91-93 (1994)
Hanefeld, F., B. Kruse, H. Bruhn and J. Frahm:
In vivo proton magnetic resonance spectroscopy of the brain in a patient with L-2-hydroxyglutaric acidemia.
Pediatric Research 35, 614-616 (1994)
Kleinschmidt, A., K. D. Merboldt, W. Haenicke, H. Steinmetz and J. Frahm:
Correlational imaging of thalamocortical coupling in the primary visual pathway of the human brain.
Journal of Cerebral Blood Flow and Metabolism 14, 952-957 (1994)
Prielmeier, F., Y. Nagatomo and J. Frahm:
Cerebral blood oxygenation in rat brain during hypoxic hypoxia: quantitative MRI of effective transverse relaxation rates.
Magnetic Resonance in Medicine 31, 678-681 (1994)
Stockler, S., U. Holzbach, F. Hanefeld, I. Marquardt, G. Helms, M. Requardt, W. Haenicke and J. Frahm:
Creatine deficiency in the brain: a new, treatable inborn error of metabolism.
Pediatric Research 36, 409-413 (1994)
1993
Frahm, J., K. D. Merboldt and W. Haenicke:
Functional MRI of human brain activation at high spatial resolution.
Magnetic Resonance in Medicine 29, 139-144 (1993)
Hanefeld, F., U. Holzbach, B. Kruse, E. Wilichowski, H. J. Christen and J. Frahm:
Diffuse white matter disease in three children: an encephalopathy with unique features on magnetic resonance imaging and proton magnetic resonance spectroscopy.
Neuropediatrics 24, 244-248 (1993)
Kruse, B., F. Hanefeld, H. J. Christen, H. Bruhn, T. Michaelis, W. Haenicke and J. Frahm:
Alterations of brain metabolites in metachromatic leukodystrophy as detected by localized proton magnetic resonance spectroscopy in vivo.
Journal of Neurology 241, 68-74 (1993)
Merboldt, K. D., D. Hoerstermann, W. Haenicke, H. Bruhn and J. Frahm:
Molecular self-diffusion of intracellular metabolites in rat brain in vivo investigated by localized proton NMR diffusion spectroscopy.
Magnetic Resonance in Medicine 29, 125-129 (1993)
Michaelis, T., K. D. Merboldt, H. Bruhn, W. Haenicke and J. Frahm:
Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra.
Radiology 187, 219-227 (1993)
Michaelis, T., G. Helms, K. D. Merboldt, W. Haenicke, H. Bruhn and J. Frahm:
Identification of Scyllo-inositol in proton NMR spectra of human brain in vivo.
NMR in Biomedicine 6, 105-109 (1993)
Prielmeier, F., K. D. Merboldt, W. Haenicke and J. Frahm:
Dynamic high-resolution MR imaging of brain deoxygenation during transient anoxia in the anesthetized rat.
Journal of Cerebral Blood Flow and Metabolism 13, 889-894 (1993)
1992
Bruhn, H., T. Michaelis, K. D. Merboldt, W. Haenicke, M. L. Gyngell, C. Hamburger and J. Frahm:
On the interpretation of proton NMR spectra from brain tumors invivo and invitro.
NMR in Biomedicine 5, 253-258 (1992)
Bruhn, H., J. Frahm, K. D. Merboldt, W. Haenicke, F. Hanefeld, H. J. Christen, B. Kruse and H. J. Bauer:
Multiple sclerosis in children: cerebral metabolic alterations monitored by localized proton magnetic resonance spectroscopy in vivo.
Annals of Neurology 32, 140-150 (1992)
Bruhn, H., B. Kruse, G. C. Korenke, F. Hanefeld, W. Haenicke, K. D. Merboldt and J. Frahm:
PROTON NMR-SPECTROSCOPY OF CEREBRAL METABOLIC ALTERATIONS IN INFANTILE PEROXISOMAL DISORDERS.
Journal of Computer Assisted Tomography 16, 335-344 (1992)
Frahm, J., H. Bruhn, K. D. Merboldt and W. Haenicke:
Dynamic MR imaging of human brain oxygenation during rest and photic stimulation.
JMRI-Journal of Magnetic Resonance Imaging 2, 501-505 (1992)
Fricke, H. and J. Frahm:
Evidence for lecithotrophic viviparity in the living coelacanth.
Naturwissenschaften 79, 476-479 (1992)
Merboldt, K. D., H. Bruhn, W. Haenicke, T. Michaelis and J. Frahm:
DECREASE OF GLUCOSE IN THE HUMAN VISUAL-CORTEX DURING PHOTIC-STIMULATION.
Magnetic Resonance in Medicine 25, 187-194 (1992)
Merboldt, K. D., W. Haenicke, H. Bruhn, M. L. Gyngell and J. Frahm:
DIFFUSION IMAGING OF THE HUMAN BRAIN INVIVO USING HIGH-SPEED STEAM MRI.
Magnetic Resonance in Medicine 23, 179-192 (1992)
Stoppe, G., H. Bruhn, K. D. Merboldt, T. Michaelis, W. Haenicke and J. Frahm:
ALTERATIONS IN CEREBRAL METABOLISM IN NORMAL AGING AND ALZHEIMERS DEMENTIA DETECTED BY PROTON MAGNETIC-RESONANCE SPECTROSCOPY.
European Journal of Neuroscience 19 (1992)
1991
Bruhn, H., T. Weber, V. Thorwirth and J. Frahm:
INVIVO MONITORING OF NEURONAL LOSS IN CREUTZFELDT-JAKOB DISEASE BY PROTON MAGNETIC-RESONANCE SPECTROSCOPY.
Lancet 337, 1610-1611 (1991)
Bruhn, H., T. Michaelis, K. D. Merboldt, W. Haenicke, M. L. Gyngell and J. Frahm:
MONITORING CEREBRAL GLUCOSE IN DIABETICS BY PROTON MRS.
Lancet 337, 745-746 (1991)
Bruhn, H., J. Frahm, M. L. Gyngell, K. D. Merboldt, W. Haenicke and R. Sauter:
LOCALIZED PROTON NMR-SPECTROSCOPY USING STIMULATED ECHOES - APPLICATIONS TO HUMAN SKELETAL-MUSCLE INVIVO.
Magnetic Resonance in Medicine 17, 82-94 (1991)
Bruhn, H., M. L. Gyngell, W. Haenicke, K. D. Merboldt and J. Frahm:
HIGH-RESOLUTION FAST LOW-ANGLE SHOT MAGNETIC-RESONANCE-IMAGING OF THE NORMAL HAND.
Skeletal Radiology 20, 259-265 (1991)
Frahm, J., H. Bruhn, W. Haenicke, K. D. Merboldt, K. Mursch and E. Markakis:
LOCALIZED PROTON NMR-SPECTROSCOPY OF BRAIN-TUMORS USING SHORT-ECHO TIME STEAM SEQUENCES.
Journal of Computer Assisted Tomography 15, 915-922 (1991)
Frahm, J., H. Bruhn, T. Michaelis, K. D. Merboldt, W. Haenicke and M. L. Gyngell:
LOCALIZED PROTON MR SPECTROSCOPY - A NONINVASIVE WAY TO INSIGHTS INTO BRAIN METABOLISM.
Radiologe 31, 558-566 (1991)
Frahm, J., W. Haenicke, H. Bruhn, M. L. Gyngell and K. D. Merboldt:
HIGH-SPEED STEAM MRI OF THE HUMAN HEART.
Magnetic Resonance in Medicine 22, 133-142 (1991)
Frahm, J., T. Michaelis, K. D. Merboldt, W. Haenicke, M. L. Gyngell and H. Bruhn:
ON THE N-ACETYL METHYL RESONANCE IN LOCALIZED H-1-NMR SPECTRA OF HUMAN BRAIN INVIVO.
NMR in Biomedicine 4, 201-204 (1991)
Gyngell, M. L., J. Ellermann, T. Michaelis, W. Haenicke, K. D. Merboldt, H. Bruhn and J. Frahm:
NONINVASIVE H-1-NMR SPECTROSCOPY OF THE RAT-BRAIN INVIVO USING A SHORT ECHO TIME STEAM LOCALIZATION SEQUENCE.
NMR in Biomedicine 4, 150-156 (1991)
Gyngell, M. L., T. Michaelis, D. Hoerstermann, H. Bruhn, W. Haenicke, K. D. Merboldt and J. Frahm:
CEREBRAL GLUCOSE IS DETECTABLE BY LOCALIZED PROTON NMR-SPECTROSCOPY IN NORMAL RAT-BRAIN INVIVO.
Magnetic Resonance in Medicine 19, 489-495 (1991)
Hanefeld, F., H. J. Bauer, H. J. Christen, B. Kruse, H. Bruhn and J. Frahm:
MULTIPLE-SCLEROSIS IN CHILDHOOD - REPORT OF 15 CASES.
Brain & Development 13, 410-416 (1991)
Merboldt, K. D., W. Haenicke and J. Frahm:
DIFFUSION IMAGING USING STIMULATED ECHOES.
Magnetic Resonance in Medicine 19, 233-239 (1991)
Michaelis, T., K. D. Merboldt, W. Haenicke, M. L. Gyngell, H. Bruhn and J. Frahm:
ON THE IDENTIFICATION OF CEREBRAL METABOLITES IN LOCALIZED H-1-NMR SPECTRA OF HUMAN BRAIN INVIVO.
NMR in Biomedicine 4, 90-98 (1991)
1990
Chandrakumar, N.:
APPLICATION OF LOWDIN PROJECTORS TO EVALUATE DENSITY-MATRIX EVOLUTIONS.
Journal of Magnetic Resonance 88, 86-92 (1990)
Chien, D., K. D. Merboldt, W. Haenicke, H. Bruhn, M. L. Gyngell and J. Frahm:
ADVANCES IN CARDIAC APPLICATIONS OF SUBSECOND FLASH MRI.
Magnetic Resonance Imaging 8, 829-836 (1990)
Frahm, J., T. Michaelis, K. D. Merboldt, H. Bruhn, M. L. Gyngell and W. Haenicke:
IMPROVEMENTS IN LOCALIZED PROTON NMR-SPECTROSCOPY OF HUMAN BRAIN - WATER SUPPRESSION, SHORT ECHO TIMES, AND 1-ML RESOLUTION.
Journal of Magnetic Resonance 90, 464-473 (1990)
Frahm, J., K. D. Merboldt, H. Bruhn, M. L. Gyngell, W. Haenicke and D. Chien:
0.3-SECOND FLASH MRI OF THE HUMAN-HEART.
Magnetic Resonance in Medicine 13, 150-157 (1990)
Haenicke, W., K. D. Merboldt, D. Chien, M. L. Gyngell, H. Bruhn and J. Frahm:
SIGNAL STRENGTH IN SUBSECOND FLASH MAGNETIC-RESONANCE-IMAGING - THE DYNAMIC APPROACH TO STEADY-STATE.
Medical Physics 17, 1004-1010 (1990)
Merboldt, K. D., D. Chien, W. Haenicke, M. L. Gyngell, H. Bruhn and J. Frahm:
LOCALIZED P-31 NMR-SPECTROSCOPY OF THE ADULT HUMAN BRAIN INVIVO USING STIMULATED-ECHO (STEAM) SEQUENCES.
Journal of Magnetic Resonance 89, 343-361 (1990)
Sauter, R., W. Loeffler, H. Bruhn and J. Frahm:
THE HUMAN BRAIN - LOCALIZED H-1 MR SPECTROSCOPY AT 1.0-T.
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