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The aim of our research group is to understand the structural basis of spliceosomal assembly, remodeling and catalysis at atomic level. Our main tool of investigation is X-ray crystallography, often complemented by biochemical, biophysical and genetic methods.
The laboratory is equipped with state-of-the-art infrastructure for recombinant expression in insect cells and bacteria, protein purification and characterization as well as automated crystallization. We have an in-house rotating anode and regular access to several synchrotron beamlines.
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Dr. Vladimir Pena
Telefon: +49 551 201-1046 |
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Email: vpena@gwdg.de
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