The group works on the analysis of proteins, protein complexes, nucleic acids and ribonucleoprotein (RNP) complexes, using electrospray ionisation (ESI) and matrix-assisted laser desorption/ionisation (MALDI) mass spectrometry.
Our central research topics are in the development of methods for the efficient and sensitive analysis of protein content (proteomics), the detection of (post-translational) modifications and the mass-spectrometric quantification of protein components.
A major area of our activity - in collaboration with the Department of Cellular Biochemistry - is the identification of protein-RNA contacts sites in native protein-RNA complexes following cross-linking. A further central area is the quantitative mass-spectrometric analysis of synaptic proteins, in collaboration with the Department of Neurobiology. We also collaborate intensively with the institute of Molecular and Cellular Immunology at the UKG of the Georg-August-University Göttingen in the quantitative mass spectrometrical analyses of B-cell and other cell signalling processes. The core facility “Mass Spectrometry” is part of the Bioanalytical Mass Spectrometry Group.
Head
Prof. Dr. Henning Urlaub
Telefon: +49 551 201-1060
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