Die Einträge für die Jahre 2011 und 2012 sind unvollständigPublikationen Abteilung NMR-basierte Strukturbiologie
2011
Balija, M. B. G., C. Griesinger, A. Herzig, M. Zweckstetter and H. Jäckle:
Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila.
PLoS ONE 6, e24701 (2011)
Ban, D., M. Funk, R. Gulich, D. Egger, T. M. Sabo, K. F. A. Walter, R. B. Fenwick, K. Giller, F. Pichierri, B. L. de Groot, O. F. Lange, H. Grubmüller, X. Salvatella, M. Wolf, A. Loidl, R. Kree, S. Becker, N. A. Lakomek, D. Lee, P. Lunkenheimer and C. Griesinger:
relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and mu s motion of proteins.
Journal of Biomolecular NMR 50, 147-155 (2011)
Binolfi, A., A. A. Valiente-Gabioud, R. Duran, M. Zweckstetter, C. Griesinger and C. O. Fernandez:
Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy.
Journal of the American Chemical Society 133, 194-196 (2011)
Cho, M. K., H. Y. Kim, C. O. Fernandez, S. Becker and M. Zweckstetter:
Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein.
Protein Science 20, 387-395 (2011)
Cordeiro, T. N., H. Schmidt, C. Madrid, A. Juarez, P. Bernado, C. Griesinger, J. Garcia and M. Pons:
Indirect DNA readout by an H-NS related protein: Structure of the DNA complex of the C-terminal domain of Ler.
PLoS Pathogens 7, e1002380 (2011)
Erdelyi, M., E. d'Auvergne, A. Navarro-Vazquez, A. Leonov and C. Griesinger:
Dynamics of the glycosidic bond: Conformational space of lactose.
Chemistry-A European Journal 17, 9368-9376 (2011)
Fenwick, R. B., S. Esteban-Martin, B. Richter, D. Lee, K. F. A. Walter, D. Milovanovic, S. Becker, N. A. Lakomek, C. Griesinger and X. Salvatella:
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition.
Journal of the American Chemical Society 133, 10336-10339 (2011)
Gruene, T., M. K. Cho, I. Karyagina, H. Y. Kim, C. Grosse, K. Giller, M. Zweckstetter and S. Becker:
Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy.
Journal of Biomolecular NMR 49, 111-119 (2011)
Haiech, J., C. W. Heizmann and J. Krebs: The 11(th) meeting of the european calcium society. In: Biochimica et Biophysica Acta-Molecular Cell Research, 1813, 5, (2011) 908
Hallwass, F., M. Schmidt, H. Sun, A. Mazur, G. Kummerloewe, B. Luy, A. Navarro-Vazquez, C. Griesinger and U. M. Reinscheid:
Residual chemical shift anisotropy (RCSA): A tool for the analysis of the configuration of small molecules.
Han, B., U. M. Reinscheid, W. H. Gerwick and H. Gross:
The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods.
Journal of Molecular Structure 989, 109-113 (2011)
Janowicz, A., M. Michalak and J. Krebs:
Stress induced subcellular distribution of ALG-2, RBM22 and hS1u7.
Biochimica et Biophysica Acta-Molecular Cell Research 1813, 1045-1049 (2011)
Karyagina, I., S. Becker, K. Giller, D. Riedel, T. M. Jovin, C. Griesinger and M. Bennati:
Electron paramagnetic resonance spectroscopy measures the distance between the external β-strands of folded α-synuclein in amyloid fibrils.
Biophysical Journal 101, L1-L3 (2011)
Keller, O., M. Kollmar, M. Stanke and S. Waack:
A novel hybrid gene prediction method employing protein multiple sequence alignments.
Bioinformatics 27, 757-763 (2011)
Krebs, J., J. Groenendyk and M. Michalak:
Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses.
Neurochemical Research 36, 1198-1211 (2011)
Krebs, J.:
Calcium waves in Warszawa.
Biochimica et Biophysica Acta-Molecular Cell Research 1813, 909-912 (2011)
Kretzschmar, H., J. Wagner, S. Ryazanaov, A. Leonov, J. Levin, S. Shi, C. Prix, M. Groschup, C. Griesinger and A. Giese: Causal therapy of prion and Parkinson's disease with novel inhibitors of protein aggregation. In: Journal of Neuropathology and Experimental Neurology, 70, 6, (2011) 505
Lamberto, C. R., V. Torres-Monserrat, C. W. Bertoncini, X. Salvatella, M. Zweckstetter, C. Griesinger and C. O. Fernandez:
Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly.
Journal of Biological Chemistry 286, 32036-32044 (2011)
Long, D., D. W. Li, K. F. A. Walter, C. Griesinger and R. Brueschweiler:
Toward a predictive understanding of slow methyl group dynamics in proteins.
Biophysical Journal 101, 910-915 (2011)
Loquet, A., G. Lv, K. Giller, S. Becker and A. Lange:
13C spin dilution for simplified and complete solid-state NMR resonance assignment of insoluble biological assemblies.
Journal of the American Chemical Society 133, 4722-4725 (2011)
Orcellet, M. L. and C. O. Fernandez:
Structures behind the amyloid aggregation of alpha-synuclein: an NMR based approach.
Current Protein and Peptide Science 12, 188-205 (2011)
Perez-Balado, C., H. Sun, C. Griesinger, A. R. de Lera and A. Navarro-Vazquez:
Residual dipolar coupling enhanced NMR spectroscopy and chiroptics: A powerful combination for the complete elucidation of symmetrical small molecules.
Chemistry-A European Journal 17, 11983-11986 (2011)
Peters, F., M. Maestre-Martinez, A. Leonov, L. Kovacic, S. Becker, R. Boelens and C. Griesinger:
Cys-Ph-TAHA: A lanthanide binding tag for RDC and PCS enhanced protein NMR.
Journal of Biomolecular NMR 51, 329-337 (2011)
Rezaei-Ghaleh, N., K. Giller, S. Becker and M. Zweckstetter:
Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation.
Biophysical Journal 101, 1202-1211 (2011)
Schneider, R., M. C. Schuhmacher, H. Mueller, D. Nand, V. Klaukien, H. Heise, D. Riedel, G. Wolf, E. Behrmann, S. Raunser, R. Seidel, M. Engelhard and M. Baldus:
Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy.
Journal of Molecular Biology 412, 121-136 (2011)
Sun, H., U. M. Reinscheid, E. L. Whitson, E. J. d'Auvergne, C. M. Ireland, A. Navarro-Vazquez and C. Griesinger:
Challenge of large-scale motion for residual dipolar coupling based analysis of configuration: The case of fibrosterol sulfate A.
Journal of the American Chemical Society 133, 14629-14636 (2011)
Sun, H., E. J. d'Auvergne, U. M. Reinscheid, L. C. Dias, C. K. Z. Andrade, R. O. Rocha and C. Griesinger:
Bijvoet in solution reveals unexpected stereoselectivity in a Michael addition.
Chemistry 17, 1811-1817 (2011)
Walter, K.:
Correlated and further dynamics in proteins by NMR spectroscopy.
Protein dynamics detected in a membrane-embedded potassium channel using two-dimensional solid-state NMR spectroscopy.
Biochemica et Biophysica Acta - Biomembranes 1798, 268-290 (2010)
Bartoschek, S., T. Klabunde, E. Defossa, V. Dietrich, S. Stengelin, C. Griesinger, T. Carlomagno, I. Focken and K. U. Wendt:
Drug design for G-protein-coupled receptors by a ligand-based NMR method.
Angewandte Chemie International Edition 49, 1426-1429 (2010)
Binolfi, A., E. E. Rodriguez, D. Valensin, N. D'Amelio, E. Ippoliti, G. Obal, R. Duran, A. Magistrato, O. Pritsch, M. Zweckstetter, G. Valensin, P. Carloni, L. Quintanar, C. Griesinger and C. O. Fernandez:
Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein.
Inorganic Chemistry 49, 10668-10679 (2010)
Cho, M. K., H. Y. Kim, C. O. Fernandez, S. Becker and M. Zweckstetter:
Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein.
Protein Science 20, 387-395 (2010)
Dallmann, A., L. Dehmel, T. Peters, C. Muegge, C. Griesinger, J. Tuma and N. P. Ernsting:
2-aminopurine incorporation perturbs the dynamics and structure of DNA.
de la Cruz, L., R. Bajaj, S. Becker and M. Zweckstetter:
The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences.
Protein Science 19, 2045-2054 (2010)
Dervillez, X., V. Klaukien, R. Duerr, J. Koch, A. Kreutz, T. Haarmann, M. Stoll, D. Lee, T. Carlomagno, B. Schnierle, K. Moebius, C. Koenigs, C. Griesinger and U. Dietrich:
Peptide ligands selected with CD4-induced epitopes on native dualtropic HIV-1 envelope proteins mimic extracellular coreceptor domains and bind to HIV-1 gp120 independently of coreceptor usage.
Journal of Virology 84, 10131-10138 (2010)
Himmel, S., S. Wolff, S. Becker, D. Lee and C. Griesinger:
Detection and identification of protein-phosphorylation sites in histidines through HNP correlation patterns.
Krahn, A., P. Lottmann, T. Marquardsen, A. Tavernier, M. T. Tuerke, M. Reese, A. Leonov, M. Bennati, P. Hoefer, F. Engelke and C. Griesinger:
Shuttle DNP spectrometer with a two-center magnet.
Physical Chemistry Chemical Physics 12, 5830-5840 (2010)
Kumar, A., H. Heise, M. J. J. Blommers, P. Krastel, E. Schmitt, F. Petersen, S. Jeganathan, E. M. Mandelkow, T. Carlomagno, C. Griesinger and M. Baldus:
Interaction of Epothilone B (Patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy.
Poyraz, O., H. Schmidt, K. Seidel, F. Delissen, C. Ader, H. Tenenboim, C. Goosmann, B. Laube, A. F. Thuenemann, A. Zychlinsky, M. Baldus, A. Lange, C. Griesinger and M. Kolbe:
Protein refolding is required for assembly of the type three secretion needle.
Nature Structural and Molecular Biology 17, 788-792 (2010)
Reese, M.:
Sensitivity enhancement of liquid-state NMR and improvement of the INPHARMA method.
Reinscheid, U. M., M. Koeck, C. Cychon, V. Schmidts, C. M. Thiele and C. Griesinger:
The absolute configuration of dibromopalau'amine.
European Journal of Organic Chemistry 6900-6903 (2010)
Rodriguez-Castaneda, F., N. Coudevylle, S. Becker, N. Brose, T. Carlomagno and C. Griesinger:
1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex.
Biomolecular NMR Assigments 4, 45-48 (2010)
Rodriguez-Castaneda, F., M. Maestre Martinez, N. Coudevylle, K. Dimova, H. Junge, N. Lipstein, D. Lee, S. Becker, N. Brose, O. Jahn, T. Carlomagno and C. Griesinger:
Modular architecture of Munc13/calmodulin complexes: Dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
The EMBO Journal 29, 680-691 (2010)
Scheu, P. D., O. B. Kim, C. Griesinger and G. Unden:
Sensing by the membrane-bound sensor kinase DcuS: Exogenous versus endogenous sensing of C-4-dicarboxylates in bacteria.
Future Microbiology 5, 1383-1402 (2010)
Schneider, R., M. Etzkorn, K. Giller, V. Daebel, J. Eisfeld, M. Zweckstetter, C. Griesinger, S. Becker and A. Lange:
The native conformation of the human VDAC1 N terminus.
Angewandte Chemie - International Edition 49, 1882-1885 (2010)
Schneider, R., K. Seidel, M. Etzkorn, A. Lange, S. Becker and M. Baldus:
Probing molecular motion by double-quantum (13C,13C) solid-state NMR spectroscopy: application to ubiquitin.
Journal of the American Chemical Society 132, 223-233 (2010)
Skora, L., S. Becker and M. Zweckstetter:
Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR.
ChemBioChem 11, 1829-1832 (2010)
Skora, L., S. Becker and M. Zweckstetter:
Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin.
Journal of the American Chemical Society 132, 9223-9225 (2010)
Sun, H., L. Dinan, R. Lafont, A. Suksamrarn, C. Griesinger, U. Reinscheid and S. Lapenna:
Absolute configuration and docking study of canescensterone, a potent phytoecdysteroid, with non-lepidopteran ecdysteroid receptor selectivity.
European Journal of Organic Chemistry 5791-5799 (2010)
Villinger, S., R. Briones, K. Giller, U. Zachariae, A. Lange, B. L. de Groot, C. Griesinger, S. Becker and M. Zweckstetter:
Functional dynamics in the voltage-dependent anion channel.
Proceedings of the National Academy of Sciences of the United States of America 107, 22546-22551 (2010)
2009
Ader, C., R. Schneider, S. Hornig, P. Velisetty, V. Vardanyan, K. Giller, I. Ohmert, S. Becker, O. Pongs and M. Baldus:
Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity.
EMBO Journal 28, 2825-2834 (2009)
Ader, C., R. Schneider, K. Seidel, M. Etzkorn, S. Becker and M. Baldus:
Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy.
Journal of the American Chemical Society 131, 170-176 (2009)
Cho, M. K., G. Nodet, H. K. Kim, M. R. Jensen, P. Bernado, C. O. Fernandez, S. Becker, M. Blackledge and M. Zweckstetter:
Structural characterization of α-synuclein in an aggregation prone state.
Protein Science 18, 1840-1846 (2009)
Dimova, K., S. Kalkhof, I. Pottratz, C. Ihling, F. Rodriguez-Castaneda, T. Liepold, C. Griesinger, N. Brose, A. Sinz and O. Jahn:
Structural insights into the Calmodulin−Munc13 interaction obtained by cross-linking and mass spectrometry.
Biochemistry 48, 5908-5921 (2009)
Fares, C., N. A. Lakomek, K. Walter, B. T. C. Frank, J. Meiler, S. Becker and C. Griesinger:
Accessing ns-us side-chain dynamics in ubiquitin with methyl RDCs.
Journal of Biomolecular NMR 45, 23-44 (2009)
Fischer, D., M. D. Mukrasch, J. Biernat, S. Bibow, M. Blackledge, C. Griesinger, E. Mandelkow and M. Zweckstetter:
Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules.
Biochemistry 48, 10047-10055 (2009)
Frank, B. T. C.:
Investigation of protein structure and dynamics.
Universität Göttingen, Göttingen (2009)
Friedland, G. D., N. A. Lakomek, C. Griesinger, J. Meiler and T. Kortemme:
A correspondence between solution-state dynamics of an individual protein and the sequence and conformational divertisy of its family.
PLoS Computational Biology e1000393 (2009)
Gross, H., A. T. Wright, U. M. Reinscheid and G. M. Koenig:
Three new spongian diterpenes from the fijian marine sponge Spongia sp.
Natural Product Communications 4, 315-322 (2009)
Haiech, J., C. W. Heizmann and J. Krebs: The 10th European symposium on calcium-binding proteins in normal and transformed cells. In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1793, 6, (2009) 931-932
Han, S.:
Konformations- und Konfigurationsbestimmung von Canescensteron und einem Evans-Produkt mittels isotroper und anisotroper NMR-Parameter.
Universität Göttingen, Göttingen (2009)
Jensen, M. R., P. R. Markwick, S. Meier, C. Griesinger, M. Zweckstetter, S. Grzesiek, P. Bernardo and M. Blackledge:
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings.
Structure 17, 1169-1185 (2009)
Karpinar, P., M. B. Gajula Balija, S. Kuegler, F. Opazo, N. Rezaei-Ghaleh, N. Wender, H. Y. Kim, G. Taschenberger, B. H. Falkenburger, H. Heise, A. Kumar, D. Riedel, L. Fichtner, A. Voigt, G. H. Braus, K. Giller, S. Becker, A. Herzig, M. Baldus, H. Jaeckle, S. Eimer, J. B. Schulz, C. Griesinger and M. Zweckstetter:
Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models.
EMBO Journal 28, 3256-3268 (2009)
Kim, H. Y., M. K. Cho, A. Kumar, E. Maier, C. Siebenhaar, S. Becker, C. O. Fernandez, H. A. Lashuel, R. Benz, A. Lange and M. Zweckstetter:
Structural properties of pore-forming oligomers of α-synuclein.
Journal of the American Chemical Society 131, 17482-17489 (2009)
Kinsner-Ovaskainen, A., Z. Akkan, S. Casati, S. Coecke, R. Corvi, G. Dal Negro, J. de Bruijn, O. De Silva, L. Gribaldo, C. Griesinger, J. Jaworska, J. Kreysa, G. Maxwell, P. McNamee, A. Price, P. Prieto, R. Schubert, L. Tosti, A. Worth and V. Zuang:
Overcoming barriers to validation of non-animal partial replacement methods/integrated testing strategies: The report of an EPAA-ECVAM workshop.
Alternatives to Laboratory Animals 37, 437-444 (2009)
Klingbeil, C., B. Angerstein and U. Klingbeil:
Funktionalisierung von Silicium-Nanopartikeln mit Fluorwasserstoff und Olefinen.
Zeitschrift für Anorganische und Allgemeine Chemie 635, 1520-1522 (2009)
Krebs, J.:
The influence of calcium signaling on the regulation of alternative splicing.
Biochimica et Biophysica Acta - Molecular Cell Research 1793, 979-984 (2009)
Lamberto, G. R., A. Binolfi, M. L. Orcelett, C. W. Bertoncini, M. Zweckstetter, C. Griesinger and C. O. Fernandez:
Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation.
Proceedings of the National Academy of Sciences of the United States of America 106, 21057-21062 (2009)
Mukrasch, M., S. Bibow, J. Korukottu, S. Jeganathan, J. Biernat, C. Griesinger, E. Mandelkow and M. Zweckstetter:
Structural polymorphism of 441-residue tau at single residue resolution.
PLoS Biology 7, e1000034 (2009)
Odronitz, F., S. Becker and M. Kollmar:
Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteins.
BMC Genomics 10, 173 (2009)
Orts, J., C. Griesinger and T. Carlomagno:
The INPHARMA technique for pharmacophore mapping: A theoretical guide to the method.
Journal of Magnetic Resonance 200, 64-73 (2009)
Pal, A., R. Kraetzner, T. Gruene, M. Grapp, K. Schreiber, M. Groenborg, H. Urlaub, S. Becker, A. R. Asif, J. Gaertner, G. M. Sheldrick and R. Steinfeld:
Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis.
Journal of Biological Chemistry 284, 3976-3984 (2009)
Reese, M., M. Tuerke, I. Tkach, G. Parigi, C. Luchinat, T. Marquardsen, A. Tavernier, P. Hoefer, F. Engelke, C. Griesinger and M. Bennati:
1H and 13C dynamic nuclear polarization in aqueous solution with a two-field (0.35 T/14 T) shuttle DNP spectrometer.
Journal of the American Chemical Society 131, 15086-15087 (2009)
Reinscheid, U. M.:
Accelerated hydrolysis of aspirin using alternating magnetic fields.
Nanoscale Research Letters 4, 854-857 (2009)
Reinscheid, U. M.:
Determination of the absolute configuration of two estrogenic nonylphenols in solution by chiroptical methods.
Journal of Molecular Structure 918, 14-18 (2009)
Rodriguez, D. D., C. Grosse, S. Himmel, C. Gonzalez, I. M. de Ilarduya, S. Becker, G. M. Sheldrick and I. Uson:
Crystallographic ab initio protein structure solution below atomic resolution.
Nature Methods 6, 651-654 (2009)
Salmon, L., G. Bouvignies, P. Marwick, N. A. Lakomek, S. Showalter, D. W. Li, K. Walter, C. Griesinger, R. Brueschweiler and M. Blackledge:
Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin.
Angewandte Chemie International Edition 48, 4154-4157 (2009)
Sanchez-Pedregal, V. M. and C. Griesinger:
The tubulin-binding mode of MT stabilizing and destabilizing agents studied by NMR.
In: Tubulin-binding agents: synthetic, structural and mechanistic insights, (Ed.) Carlomagno, T., Topics in current chemistry 286. Springer, Dordrecht (2009) 151-208
Schneider, R.:
Crystalline, membrane-embedded and fibrillar proteins investigated by solid-state NMR spectroscopy.
Universität Göttingen, Göttingen (2009)
Seidel, K., M. Etzkorn, R. Schneider, C. Ader and M. Baldus:
Comparative analysis of NMR chemical shift predictions for proteins in the solid phase.
Solid State Nuclear Magnetic Resonance 35, 235-242 (2009)
Seyedsayamdost, M., T. Argirevic, E. Minniham, J. Stubbe and M. Bennati:
Structural examination of the transient 3-aminotyrosyl radical on the PCET pathway of E. coli ribonucleotide reductase by multifrequency EPR spectroscopy.
Journal of the American Chemical Society 131, 15729-15738 (2009)
Skora, L.:
High-resolution characterization of structural changes involved in prion diseases and dialysis-related amyloidosis.
Vijayan, V., J. P. Demers, J. Biernat, E. Mandelkow, S. Becker and A. Lange:
Low-power solid-state NMR experiments for resonance assignment under fast magic-angle spinning.
ChemPhysChem 10, 2205-2208 (2009)
2008
Ader, C., R. Schneider, S. Hornig, P. Velisetty, E. M. Wilson, A. Lange, K. Giller, I. Ohmert, M. F. Martin-Eauclaire, D. Trauner, S. Becker, O. Pongs and M. Baldus:
A structural link between inactivation and block of a K+ channel.
Afonin, S., U. H. N. Duerr, P. Wadhwani, J. Salgado and A. S. Ulrich:
Solid state NMR structure analysis of the antimicrobial peptide gramicidin S in lipid membranes: concentration-dependent re-alignment and self-assembly as a beta-barrel.
Topics in Current Chemistry 273, 139-154 (2008)
Andronesi, O., M. von Bergen, J. Biernat, K. Seidel, C. Griesinger, E. Mandelkow and M. Baldus:
Characterization of Alzheimer’s-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy.
Journal of the American Chemical Society 130, 5922-5928 (2008)
Bayrhuber, M., T. Meins, M. Habeck, S. Becker, K. Giller, S. Villinger, C. Vonrhein, C. Griesinger, M. Zweckstetter and K. Zeth:
Structure of the human voltage-dependent anion channel.
Proceedings of the National Academy of Sciences of the United States of America 105, 15370-15375 (2008)
Becker, S. and H. Terlau:
Toxins from cone snails: properties, applications and biotechnological production.
Applied Microbiology and Biotechnology 79, 1-9 (2008)
Binolfi, A., G. R. Lamberto, R. Duran, L. Quintanar, C. W. Bertoncini, J. M. Souza, C. Cervenansky, M. Zweckstetter, C. Griesinger and C. O. Fernandez:
Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation.
Journal of the American Chemical Society 130, 11801-11812 (2008)
Cho, M. K.:
Transition of intrinsically unfolded α-synuclein into the fibrillar state characterized by NMR spectroscopy.
Universität Göttingen, Göttingen (2008)
Coudevylle, N., P. Montaville, M. Leonov, M. Zweckstetter and S. Becker:
Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.
Journal of Biological Chemistry 283, 35918-35928 (2008)
d' Auvergne, E. and P. R. Gooley:
Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor.
Journal of Biomolecular NMR 40, 121-133 (2008)
d' Auvergne, E. and P. R. Gooley:
Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces.
Journal of Biomolecular NMR 40, 107-119 (2008)
Duerr, U. H. N., S. L. Grage, R. Witter and A. S. Ulrich:
Solid state F-19 NMR parameters of fluorine-labeled amino acids. Part I: Aromatic substituents.
Journal of Magnetic Resonance 191, 7-15 (2008)
Erdelyi, M., B. Pfeiffer, K. Hauenstein, j Fohrer, J. Gertsch, K. H. Altmann and T. Carlomagno:
Conformational preferences of natural and C3-modified epothilones in aqueous solution.
Journal of Medicinal Chemistry 51, 1469-1473 (2008)
Etzkorn, M., H. Kneuper, P. Duennwald, V. Vijayan, J. Kraemer, C. Griesinger, S. Becker, G. Unden and M. Baldus:
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS.
Nature Structural and Molecular Biology 15, 1031-1039 (2008)
Etzkorn, M.:
Proteins precipitates, agregation kinetics and membrane protein receptors characterized by solid-state NMR.
Universität Göttingen, Göttingen (2008)
Fohrer, J.:
NMR-spektroskopische Untersuchungen an katalytischer RNA.
Universität Frankfurt, Frankfurt (2008)
Grage, S. L., U. H. N. Duerr, S. Afonin, P. K. Mikhailiuk, I. V. Komarov and A. S. Ulrich:
Solid state F-19 NMR parameters of fluorine-labeled amino acids. Part II: Aliphatic substituents.
Journal of Magnetic Resonance 191, 16-23 (2008)
Haertner, J. and U. M. Reinscheid:
Conformational analysis of menthol diastereomers by NMR and DFT computation.
Journal of Molecular Structure 872, 145-149 (2008)
Heise, H., M. S. Celej, S. Becker, D. Riedel, A. Pelah, A. Kumar, T. M. Jovin and M. Baldus:
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant α-synuclein.
Journal of Molecular Biology 380, 444-450 (2008)
Hoefer, P., P. Carl, G. Guthausen, T. Prisner, T. Carlomagno, M. Reese, C. Griesinger and M. Bennati:
Studies of dynamic nuclear polarization with nitroxides in aqueous solution.
Applied Magnetic Resonance 34, 393-398 (2008)
Hoefer, P., G. Parigi, C. Luchinat, P. Carl, G. Guthausern, T. Carlomagno, M. Reese, C. Griesinger and M. Bennati:
Field dependent dynamic nuclear polarization with radicals in aqueous solution.
Journal of the American Chemical Society 130, 3254-3255 (2008)
Honndorf, V.:
Untersuchung von p38aMAP-Kinase/Inhibitor-Komplexen in Lösung mittels Kernspinspektroskopie.
Universität Marburg, Marburg (2008)
Honndorf, V., N. Coudevylle, S. Laufer, S. Becker and C. Griesinger:
Dynamics in the p38αMAP kinase-SB203580 complex observed by liquid-state NMR spectroscopy.
Angewandte Chemie International Edition 47, 3548-3551 (2008)
Jedelska, J., A. Vogt, U. M. Reinscheid and M. Keusgen:
Isolation and identification of a red pigment from allium subgenus melanocrommyum.
Journal of Agricultural and Food Chemistry 56, 1465-1470 (2008)
Kim, H. Y.:
Characterization of the amyloid precursor α-synuclein by NMR spectroscopy.
Universität Göttingen, Göttingen (2008)
Korukottu, J., R. Schneider, V. Vijayan, A. Lange, O. Pongs, S. Becker, M. Baldus and M. Zweckstetter:
High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy.
PLoS ONE 3, e2359 (2008)
Lakomek, N. A., O. Lange, K. Walter, C. Fares, D. Egger, P. Lunkenheimer, J. Meiler, H. Grubmueller, S. Becker, B. L. de Groot and C. Griesinger:
Residual dipolar couplings as a tool to study molecular recognition of ubiquitin.
Biochemical Society Transactions 36, 1433-1437 (2008)
Lakomek, N. A., K. Walter, C. Fares, O. Lange, B. L. de Groot, H. Grubmueller, R. Brueschweiler, A. Munk, S. Becker, J. Meiler and C. Griesinger:
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics.
Journal of Biomolecular NMR 41, 139-155 (2008)
Lakomek, N. A.:
New methods in NMR spectroscopy for the study of protein dynamics.
Universität Göttingen, Göttingen (2008)
Lange, O., N. A. Lakomek, C. Fares, G. F. Schroeder, K. Walter, S. Becker, J. Meiler, H. Grubmueller, C. Griesinger and B. L. de Groot:
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science 320, 1471-1475 (2008)
Lee, D., K. Walter, A. K. Brueckner, C. Hilty, S. Becker and C. Griesinger:
Bilayer in small bicelles revealed by lipid−protein interactions using NMR spectroscopy.
Journal of the American Chemical Society 130, 13822-13823 (2008)
Lodrini, M., T. Munz, N. Coudevylle, C. Griesinger, S. Becker and E. Pfitzner:
p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.
Nucleic Acids Research 36, 1847-1860 (2008)
Montaville, P., N. Condevylle, A. Radhakrishnan, A. Leonov, M. Zweckstetter and S. Becker:
The PIP2 binding mode of the C2 domains of rabphilin-3A.
Protein Science 17, 1025-1034 (2008)
Mukrasch, M.:
Untersuchung des Tau-Proteins mit Hilfe von NMR-Spektroskopie.
Universität Frankfurt, Frankfurt (2008)
Orts, J., J. Tuma, M. Reese, S. K. Grimm, P. Monecke, S. Bartoschek, A. Schiffer, U. Wendt, C. Griesinger and T. Carlomagno:
Crystallography-independent determination of ligand binding modes.
Angewandte Chemie International Edition 47, 7736-7740 (2008)
Orts, J., S. K. Grimm, C. Griesinger, K. U. Wendt, S. Bartoschek and T. Carlomagno:
Specific methyl group protonation for the measurement of pharmacophore-specific interligand NOE interactions.
Chemistry 14, 7517-7520 (2008)
Pongs, O., C. Ader, R. Schneider, S. Hornig, P. Velisetty, E. M. Wilson, A. Lange, K. Giller, M. F. Martin-Eauclaire, D. Trauner, S. Becker and M. Baldus: A structural link between potassium channel gating and drug binding. In: FEBS Journal, 275, Suppl. 1, (2008) 174
Reese, M., D. Lennartz, T. Marquardsen, P. Hoefer, A. Tavernier, P. Carl, T. Schippmann, M. Bennati, T. Carlomagno, F. Engelke and C. Griesinger:
Construction of a liquid-state NMR DNP shuttle spectrometer: first experimental results and evaluation of optimal performance characteristics.
Applied Magnetic Resonance 34, 301-311 (2008)
Rumpel, S., R. Lakshmi, S. Becker and M. Zweckstetter:
Assignment-free solution NMR method reveals CesT as an unswapped homodimer.
Protein Science 17, 2015-2019 (2008)
Rumpel, S., S. Becker and M. Zweckstetter:
High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment.
Journal of Biomolecular NMR 40, 1-13 (2008)
Schlicker, C., O. Fokina, N. Kloft, T. Gruene, S. Becker, G. M. Sheldrick and K. Forchhammer:
Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible Ffap subdomain controls access to the catalytic site.
Journal of Molecular Biology 376, 570-581 (2008)
Schneider, R., C. Ader, A. Lange, K. Giller, S. Hornig, O. Pongs, S. Becker and M. Baldus:
Solid-state NMR spectroscopy applied to a chimeric potassium channel in lipid bilayers.
Journal of the American Chemical Society 130, 7427-7435 (2008)
Schuetz, A., T. Murakami, N. Takada, J. Junker, M. M. Hashimoto and C. Griesinger:
RDC-enhanced NMR spectroscopy in structure elucidation of sucro-neolambertellin.
Angewandte Chemie International Edition 47, 2032-2034 (2008)
Seidel, K., O. Andronesi, J. Krebs, C. Griesinger, H. S. Young, S. Becker and M. Baldus:
Structural characterization of Ca2+-ATPase-bound phospholamban in lipid bilayers by solid-state nuclear magnetic resonance (NMR) spectroscopy.
Biochemistry 47, 4369-4376 (2008)
Seidel, K.:
Structural characterization of membrane proteins by solid-state NMR spectroscopy.
Universität Göttingen, Göttingen (2008)
Sevvana, M., V. Vijayan, M. Zweckstetter, S. Reinelt, D. R. Madden, R. Herbst-Irmer, G. M. Sheldrick, M. Bott, C. Griesinger and S. Becker:
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA.
Journal of Molecular Biology 377, 512-523 (2008)
Soragni, A., B. Zambelli, M. Mukrasch, J. Biernat, S. Jeganathan, C. Griesinger, S. Ciurli, E. Mandelkow and M. Zweckstetter:
Structural characterization of binding of Cu(II) to Tau protein.
Biochemistry 47, 10841-10851 (2008)
Suardiaz, R., M. Maestre Martinez, E. Suarez, Y. Bernardo, E. Alonso-Becerra and C. Perez:
Molecular dynamics and NMR analysis of the configurational 13C assignment of epimeric 22,23-epoxides of stigmasterol.
Journal of Physical Chemistry A 112, 8333-8336 (2008)
von Feilitzsch, T., J. Tuma, H. Neubauer, L. Verdier, R. Haselsberger, R. Feick, G. Gurzadyan, A. A. Voityuk, C. Griesinger and M. E. Michel-Beyerle:
Chromophore/DNA interactions: Femto- to nanosecond spectroscopy, NMR structure, and electron transfer theory.
Journal of Physical Chemistry B 112, 973-989 (2008)
Zachariae, U., R. Schneider, P. Velisetty, A. Lange, D. Seeliger, S. Wacker, J. Karimi-Nejad, G. Vriend, S. Becker, O. Pongs, M. Baldus and B. L. de Groot:
The molecular mechanism of toxin-induced conformational changes in a potassium channel: relation to C-type inactivation.
Structure 16, 747-754 (2008)
2007
Bayrhuber, M.:
Structural and functional characterisation of the mitochondrial membrane protein human voltagedependent anion channel (HVDAC) and the membrane protein-targeting Conotoxin Conkunitzin-S1 by solution NMR.
Universität Göttingen, Göttingen (2007)
Bertoncini, C. W., R. M. Rasia, G. R. Lamberto, A. Binolfi, M. Zweckstetter, C. Griesinger and C. O. Fernandez:
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation.
Journal of Molecular Biology 372, 708-722 (2007)
Carlomagno, T., M. Baldus and C. Griesinger:
Bio-nuclear magnetic resonance.
In: Drug discovery technologies, (Ed.) Kubinyi, H., Comprehensive medicinal chemistry II 3. Elsevier, Amsterdam (2007) 473-505
De Gortari, I., M. Galvan, J. Ireta, M. Segall, C. J. Pickard and M. Payne:
Theoretical investigations of oxygen-17 NMR chemical shifts to discriminate among helical forms.
Journal of Physical Chemistry A 111, 13099-13105 (2007)
Fischer, D., M. Mukrasch, M. von Bergen, A. Klos-Witkowska, J. Biernat, C. Griesinger, E. Mandelkow and M. Zweckstetter:
Structural and microtubule binding properties of tau mutants of frontotemporal dementias.
Biochemistry 46, 2574-2582 (2007)
Haberz, P.:
Development and application of NMR-methods for structural investigations of small molecules and proteins.
Universität Göttingen, Göttingen (2007)
Keusgen, M., A. Vogt, J. Jedelsk and U. M. Reinscheid: Sulphur pyrroles from Allium subgenus Melanocrommyum - a new class of pigments. In: Planta Media, 73, 9, (2007) 806
Kim, H. Y., H. Heise, C. O. Fernandez, M. Baldus and M. Zweckstetter:
Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein.
ChemBioChem 8, 1671-1674 (2007)
Klaukien, V.:
Synthese und NMR-spektroskopische Charakterisierung von Liganden für die CD4-indizierten Epitope im Hüllprotein gp120 von HIV-1.
Universität Braunschweig, Braunschweig (2007)
Koenigs, C., A. Pustowka, I. Irving, C. Kessel, K. Klich, V. Wegner, M. J. Rowley, I. R. Mackay, W. Kreuz, C. Griesinger and U. Dietrich:
Peptide mimotopes selected with HIV-1-blocking monoclonal antibodies against CCR5 represent motifs specific for HIV-1 entry.
Immunology and Cell Biology 85, 511-517 (2007)
Korukottu, J., M. Bayrhuber, P. Montaville, Y. S. Jung, V. Vijayan, S. Becker and M. Zweckstetter:
Fast high-resolution protein structure determination by using unassigned NMR data.
Angewandte Chemie International Edition 46, 1176-1179 (2007)
Kraemer, J., J. D. Fischer, E. Zientz, V. Vijayan, C. Griesinger, A. Lupas and G. Unden:
Citrate sensing by the C4-dicarboxylate/citrate sensor kinase DcuS of Escherichia coli: Binding site and conversion of DcuS to a C4-dicarboxylate- or citrate-specific sensor.
Journal of Bacteriology 189, 4290-4298 (2007)
Li, P.:
Preparation and NMR spectroscopy investigation of 15.5K protein associated complexes.
Universität Göttingen, Göttingen (2007)
Montaville, P., C. Schlicker, A. Leonov, M. Zweckstetter, G. M. Sheldrick and S. Becker:
The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A.
Journal of Biological Chemistry 282, 5015-5025 (2007)
Mukrasch, M., M. von Bergen, J. Biernat, D. Fischer, C. Griesinger, E. Mandelkow and M. Zweckstetter:
The "jaws" of the tau-microtubule interaction.
Journal of Biological Chemistry 282, 12230-12239 (2007)
Mukrasch, M., P. Markwick, J. Biernat, M. von Bergen, P. Bernado, C. Griesinger, E. Mandelkow, M. Zweckstetter and M. Blackledge:
Highly populated turn conformations in natively unfolded Tau protein identified from residual dipolar couplings and molecular simulation.
Journal of the American Chemical Society 129, 5235-5243 (2007)
Neubauer, H., N. Gaiko, S. Berger, J. Schaffer, C. Eggeling, J. Tuma, L. Verdier, C. Seidel, C. Griesinger and A. Volkmer:
Orientational and dynamical heterogeneity of rhodamine 6G terminally attached to a DNA helix revealed by NMR and single-molecule fluorescence spectroscopy.
Journal of the American Chemical Society 129, 12746-12755 (2007)
Pongs, O., S. Hornig, A. Lange, K. Giller, R. Schneider, M. F. Eauclaire, D. Trauner, S. Becker and M. Baldus: Structural and functional analysis of a potassium channel in complex with a gating modifier. In: Biophysical Journal, (2007) 76A
Raghunathan, D.:
TAR-RNA recognition by a novel cyclic aminoglycoside analogue.
Universität Göttingen, Göttingen (2007)
Reese, M., V. M. Sanchez-Pedregal, K. Kubicek, J. Meiler, M. J. J. Blommers, C. Griesinger and T. Carlomagno:
Structural basis of the activity of the microtubule-stabilizing agent epothilone A studied by NMR spectroscopy in solution.
Konformationsanalyse von Naturstoffen und ihren Derivaten anhand von NMR-Parametern und computerchemischen Rechnungen.
Philipps-Universität Marburg, Marburg (2007)
Rodriguez-Castaneda, F.:
NMR Spetroscopic studies of calmodulin plasticity in calcium signalling.
Universität Göttingen, Göttingen (2007)
Schuetz, A., J. Junker, A. Leonov, O. Lange, T. F. Molinski and C. Griesinger:
Stereochemistry of sagittamide a from residual dipolar coupling enhanced NMR.
Journal of the American Chemical Society 129, 15114-15115 (2007)
Schuetz, A.:
Konformation und Konfiguration von kleinen Molekülen mittels NMR-Spektroskopie.
Universität Göttingen, Göttingen (2007)
Tuma, J., S. Tonzani, G. C. Schatz, A. H. Karaba and F. D. Lewis:
Structure and electronic spectra of DNA mini-hairpins with G(n): C-n stems.
Journal of Physical Chemistry B 111, 13101-13106 (2007)
Vijayan, V.:
NMR structural studies on the periplasmic domain of CitA and Dcus.
Universität Göttingen, Göttingen (2007)
Walter, K.:
Bestimmung der Dynamik von Ubiquitin in Lösung mittels orientierungsabhäniger NMR-Parameter.
Universität Göttingen, Göttingen (2007)
Wehner, S. G., C. Boehme and U. M. Reinscheid:
Energetic, geometric and magnetic analysis of all-syn,trans cyclic cyclopropanes.
Journal of Molecular Structure-Theochem 820, 85-89 (2007)
2006
Ab, E., A. Atkinson, L. Banci, I. Bertini, S. Ciofi-baffoni, K. Brunner, T. Diercks, V. Dotsch, F. Engelke, G. E. Folkers, C. Griesinger, W. Gronwald, U. Gunther, M. Habeck, R. N. de Jong, H. R. Kalbitzer, B. Kieffer, B. R. Leeflang, S. Loss, C. Luchinat, T. Marquardsen, D. Moskau, K. P. Neidig, M. Nilges, M. Piccioli, R. Pierattelli, W. Rieping, T. Schippmann, H. Schwalbe, G. Trave, J. Trenner, J. Wohnert, M. Zweckstetter and R. Kaptein:
NMR in the SPINE structural proteomics project.
Acta Crystallographica Section D 62, 1150-1161 (2006)
Andronesi, O., H. Heise and M. Baldus:
Determining protein 3D structure by magic-angle-spinning NMR.
In: Modern magnetic resonance. Part 1. Applications in chemistry, biological and marine sciences, (Ed.) Webb, G.A., Springer, Dordrecht (2006) 523-526
Baldus, M.:
Molecular interactions investigated by multi-dimensional solid-state NMR.
Current Opinion in Structural Biology 16, 618-623 (2006)
Baldus, M.:
Solid-state NMR spectroscopy: Molecular structure and organization at the atomic level.
Binolfi, A., R. M. Rasia, C. W. Bertoncini, M. Ceolin, M. Zweckstetter, C. Griesinger, T. M. Jovin and C. O. Fernandez:
Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement.
Journal of the American Chemical Society 128, 9893-9901 (2006)
Bockelmann, D.:
Konformationelle Vielfalt: Synthese eines spleißosomalen RNA-Konstruktes, NMR-Strukturen von Minigramicidin und einem molekularen Schalter.
Carlomagno, T., D. Menche, J. Hassfeld, C. Fares and H. Steinmetz:
Stereochemical determination of archazolid A and B, highly potent vacuolar-type ATPase inhibitors from the myxobacterium Archangium gephyra.
Organic Letters 8, 4751-4754 (2006)
Carlomagno, T. and C. Griesinger:
Transferred cross-correlated relaxation: Application to drug/target complexes.
In: Modern magnetic resonance. Pt. 2, (Ed.) Graham A. Webb, Springer, Dordrecht (2006) 1229-1236
Dervillez, X., A. Huether, J. Schuhmacher, C. Griesinger, J. Cohen, D. von Laer and U. Dietrich:
Stable expression of soluble therapeutic peptides in eukaryotic cells by multimerisation: application to the HIV-1 fusion inhibitory peptide C46.
ChemMedChem 1, 330-339 (2006)
Dziadek, S., C. Griesinger, H. Kunz and U. M. Reinscheid:
Syntheses and Structural Model of γ(2,6)-sialyl-T glycosylated MUC1 Eicosapeptide under Physiological Conditions.
Chemistry - A European Journal 12, 4981-4993 (2006)
Fares, C. and T. Carlomagno:
SHARP-TACSY: Triple-band tailored correlated spectroscopy for base-to-sugar transfer in nucleic acid residues with intermediate time scale motions.
Journal of the American Chemical Society 128, 9856-9862 (2006)
Farjon, J., W. Bermel and C. Griesinger:
Resolution enhancement in spectra of natural products dissolved in weakly orienting media with the help of 1H homonuclear dipolar decoupling during acquisition: Application to 1H-13C dipolar couplings measurements.
Journal of Magnetic Resonance 180, 72-82 (2006)
Fick, A. C. and U. M. Reinscheid:
Characterization of the binding epitope of ciprofloxacin bound to human serum albumin.
Journal of Pharmaceutical and Biomedical Analysis 41, 1025-1028 (2006)
Fischer, J. T., S. G. Wehner and U. M. Reinscheid:
Interpretation of cytidine proton chemical shifts and J coupling constants calculated by DFT.
Journal of Molecular Structure-Theochem 767, 81-85 (2006)
Fischer, J. T. and U. M. Reinscheid:
C-13 chemical shifts and (1)J(CH) coupling constants of cytidine at different chi dihedrals based on DFT calculations.
European Journal of Organic Chemistry 9, 2074-2080 (2006)
Fohrer, J., M. Hennig and T. Carlomagno:
Influence of the 2´-Hydroxyl Group Conformation on the Stability of A-form Helices in RNA.
Journal of Molecular Biology 356, 280-287 (2006)
Fohrer, J., U. M. Reinscheid, M. Hennig and T. Carlomagno:
Calculation of the dependence of homo- and heteronuclear (3)J and (2)J scalar couplings for the determination of the 2 '-hydroxy conformation in RNA.
Haberz, P., F. Rodriguez-Castaneda, J. Junker, S. Becker, A. Leonov and C. Griesinger:
Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution.
Organic Letters 8, 1275-1278 (2006)
Haiech, J., C. W. Heizmann and J. Krebs: Special issue: The 9th European symposium on calcium-binding proteins in normal and transformed cells - Preface. In: Biochimica et Biophysica Acta-Molecular Cell Research, 1763, 11 Sp. Iss. SI, (2006) 1135
Iwahara, J., M. Zweckstetter and G. M. Clore:
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA.
Proceedings of the National Academy of Sciences of the United States of America 103, 15062-15067 (2006)
Jauch, R., M. K. Cho, S. Jaekel, C. Netter, K. Schreiter, B. Aicher, M. Zweckstetter, H. Jaeckle and M. C. Wahl:
Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
The EMBO Journal 25, 4020-4032 (2006)
Kollmar, M.:
Use of the myosin motor domain as large-affinity tag for the expression and purification of proteins in Dictyostelium discoideum.
International Journal of Biological Macromolecules 39, 37-44 (2006)
Kollmar, M.:
Thirteen is enough: the myosins of Dictyostelium discoideum and their light chains.
BMC Genomics 7, 183 (2006)
Lakomek, N. A., T. Carlomagno, S. Becker, C. Griesinger and J. Meiler:
A thorough dynamic interpretation of residual dipolar couplings in ubiquitin.
Journal of Biomolecular NMR 34, 101-115 (2006)
Lange, A., K. Giller, S. Hornig, M. F. Martin-Eauclaire, O. Pongs, S. Becker and M. Baldus:
Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR.
Nature 440, 959-962 (2006)
Lange, A., K. Giller, O. Pongs, S. Becker and M. Baldus:
Two-dimensional solid-state NMR applied to a chimeric potassium channel.
Journal of Receptors and Signal Transduction 26, 379-393 (2006)
Lennartz, D. and H. Strehlow:
Determination of reaction rate constants and T-2 relaxation times using integrated NMR power spectra.
Zeitschrift fur Physikalische Chemie-International Journal of Research in Physical Chemistry & Chemical Physics 220, 641-653 (2006)
Montaville, P., Y. Dai, C. Y. Cheung, K. Giller, S. Becker, M. Michalak, S. E. Webb, A. Miller and J. Krebs:
Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.
Biochimica et Biophysica Acta-Molecular Cell Research 1763, 1335-1343 (2006)
Montaville, P., H. Y. Kim, V. Vijayan, S. Becker and M. Zweckstetter: H-1, N-15, and C-13 resonance assignment of the C2A domain of rabphilin3A. In: Journal of Biomolecular NMR, 36, Suppl. 1, (2006) 20
Odronitz, F. and M. Kollmar:
Pfarao: a web application for protein family analysis customized for cytoskeletal and motor proteins (CyMoBase).
BMC Genomics 7, 300 (2006)
Peters, F.:
Synthese eines EDTA-basierten Thyminderivats, dessen Einbau in DNA und NMR-spektroskopische Charakterisierung.
Universität Göttingen, Göttingen (2006)
Raghunathan, D., V. M. Sanchez-Pedregal, J. Junker, C. Schwiegk, M. Kalesse, A. Kirschning and T. Carlomagno:
TAR RNA Recognition by a Novel Cyclic Aminoglycoside Analogue.
Nucleic Acids Research 34, 3599-3608 (2006)
Reinscheid, U. M., J. Vervoort and H. Zuilhof:
Mild hydrolysis of 2-trifluoromethylphenol: Kinetics, mechanism and environmental relevance.
Chemosphere 65, 318-323 (2006)
Reinscheid, U. M.:
Direct determination of ciprofloxacin in admixtures with metronidazol and ampicillin by NMR.
Journal of Pharmaceutical and Biomedical Analysis 40, 447-449 (2006)
Reinscheid, U. M., J. Farjon, M. Radzom, P. Haberz, A. Zeeck, M. Blackledge and C. Griesinger:
Effect of the Solvent on the Conformation of a Depsipeptide: NMR-Derived Solution Structure of Hormaomycin in DMSO from Residual Dipolar Couplings in a Novel DMSO-Compatible Alignment Medium.
ChemBioChem 7, 287-296 (2006)
Rodriguez-Castaneda, F., P. Haberz, A. Leonov and C. Griesinger:
Paramagnetic tagging of diamagnetic proteins for solution NMR.
Magnetic Resonance in Chemistry 44, S10-S16 (2006)
Rumpel, S.:
Protein NMR studies of two systems involved in bacterial pathogenicity.
Georg-August-Universität, Göttingen (2006)
Sanchez-Pedregal, V. M., K. Kubicek, J. Meiler, I. Lyothier, T. Paterson and T. Carlomagno:
The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
Watzlawik, J., L. Skora, D. Frense, C. Griesinger, M. Zweckstetter, W. Schulz-Schaeffer and M. L. Kramer:
Prion protein helix1 promotes aggregation but is not converted into beta-sheet.
Journal of Biological Chemistry 281, 30242-30250 (2006)
Zweckstetter, M.:
Prediction of charge-induced molecular alignment: Residual dipolar couplings at pH 3 and alignment in surfactant liquid crystalline phases.
European Biophysics Journal 35, 170-180 (2006)
2005
Andronesi, O., S. Becker, K. Seidel, H. Heise, H. S. Young and M. Baldus:
Determination of membrane protein structure and dynamics by magic-angle-spinning solid-state NMR spectroscopy.
Journal of the American Chemical Society 127, 12965-12974 (2005)
Bayrhuber, M., V. Vijayan, M. Ferber, R. Graf, J. Korukottu, J. Imperial, J. E. Garrett, B. M. Olivera, H. Terlau, M. Zweckstetter and S. Becker:
Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family - Structural and functional characterization.
Journal of Biological Chemistry 280, 23766-23770 (2005)
Bernado, P., C. W. Bertonconi, C. Griesinger, M. Zweckstetter and M. Blackledge:
Defining long-range order and local disorder in native α-synuclein using residual dipolar couplings.
Journal of the American Chemical Society 127, 17968-17969 (2005)
Bertoncini, C. W., C. O. Fernandez, C. Griesinger, T. M. Jovin and M. Zweckstetter:
Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation.
Journal of Biological Chemistry 280, 30649-30652 (2005)
Bertoncini, C. W., Y. S. Jung, C. O. Fernandez, W. Hoyer, C. Griesinger, T. M. Jovin and M. Zweckstetter:
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein.
Proceedings of the National Academy of Sciences of the United States of America 102, 1430-1435 (2005)
Bertoncini, C. W., D. I. Cherny, C. O. Fernandez, E. Garfinkel, C. Griesinger, W. Hoyer, E. A. Jares-Erijman, T. M. Jovin, D. Marsh, R. M. Rasia, M. J. Roberti, V. Subramaniam and M. Zweckstetter: 3D structure, ligand binding, autoinhibition, aggregation, and cellular distribution of wild-type, mutant, and labeled alpha-synuclein. In: Biophysical Journal, 88, 1, (2005) 396A
Haberz, P., J. Farjon and C. Griesinger:
A DMSO-compatible orienting medium: Towards the investigation of the stereochemistry of natural products.
Razeto, A., V. Ramakrishnan, C. M. Litterst, K. Giller, C. Griesinger, T. Carlomagno, N. A. Lakomek, T. Heimburg, M. Lodrini, E. Pfitzner and S. Becker:
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.
Journal of Molecular Biology 336, 319-329 (2004)
Rumpel, S., A. Razeto, C. M. Pillar, V. Vijayan, A. Taylor, K. Giller, M. S. Gilmore, S. Becker and M. Zweckstetter:
Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis.
EMBO Journal 23, 3632-3642 (2004)
Seidel, K., A. Lange, S. Becker, C. E. Hughes, H. Heise and M. Baldus:
Protein solid-state NMR resonance assignments from (C-13, C-13) correlation spectroscopy.
Physical Chemistry Chemical Physics 6, 5090-5093 (2004)
Shima, S., E. J. Lyon, M. S. Sordel-Klippert, M. Kauss, J. Kahnt, R. K. Thauer, K. Steinbach, X. L. Xie, L. Verdier and C. Griesinger:
The cofactor of the iron-sulfur cluster free hydrogenase Hmd: Structure of the light-inactivation product.
Multiple-spin analysis of chemical-shift-selective (C-13, C-13) transfer in uniformly labeled biomolecules.
Journal of Magnetic Resonance 166, 100-110 (2004)
Soruri, A., A. Fayyazi, S. Gangl, C. Griesinger, C. A. Albrecht and T. Schlott:
In vitro generation of cytolytic T cells against human melanoma cells overexpressing HDM2.
Anticancer Research 24, 2141-2151 (2004)
Tuma, J., R. Paulini, J. A. R. Stutz and C. Richert:
How much pi-stacking do DNA termini seek? Solution structure of a self-complementary DNA hexamer with trimethoxystilbenes capping the terminal base pairs.
Biochemistry 43, 15680-15687 (2004)
van Buuren, B. N. M., A. Schleucher, V. Wittmann, C. Griesinger, H. Schwalbe and S. S. Wijmenga:
NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides.
Bartoschek, S., G. Buurman, B. H. Geierstanger, J. Lapham and C. Griesinger:
Measurement and ab initio calculation of CSA/dipole- dipole cross-correlated relaxation provide insight into the mechanism of a H-2-forming dehydrogenase.
Journal of the American Chemical Society 125, 13308-13309 (2003)
Carlomagno, T., W. Bermel and C. Griesinger:
Measuring the chi(1) torsion angle in protein by CH-CH cross-correlated relaxation: A new resolution-optimised experiment.
Journal of Biomolecular NMR 27, 151-157 (2003)
Carlomagno, T., V. M. Sanchez, M. J. J. Blommers and C. Griesinger:
Derivation of dihedral angles from CH-CH dipolar-dipolar cross-correlated relaxation rates: A C-C torsion involving a quaternary carbon atom in epothilone A bound to tubulin.
Carlomagno, T., M. J. J. Blommers, J. Meiler, W. Jahnke, T. Schupp, F. Petersen, D. Schinzer, K. Altmann and C. Griesinger:
The high-resolution solution structure of epothilone A bound to tubulin: An understanding of the structure-activity relationships for a powerful class of antitumor agents.
Angular restraints from residual dipolar couplings for structure refinement.
In: Protein NMR for the millennium, (Ed.) R. Krishna, L. J. Berliner, Biological magnetic resonance 20. Kluwer Academic/Plenum Publ., New York (2003) 163-229
Hus, J. C., W. Peti, C. Griesinger and R. Bruschweiler:
Self-consistency analysis of dipolar couplings in multiple alignments of ubiquitin.
Journal of the American Chemical Society 125, 5596-5597 (2003)
Ivchenko, N., C. E. Hughes and M. H. Levitt:
Application of cogwheel phase cycling to sideband manipulation experiments in solid-state NMR.
