Movies and Video Clips
Nanoscopy with Focused Light
Super-sharp Images of the Brain
To explore the most intricate structures of the brain in order to decipher how it functions Stefan Hell’s team of researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen has made a significant step closer to this goal. Using the STED microscopy developed by Hell, the scientists have, for the first time, managed to record detailed live images inside the brain of a living mouse. Captured in the previously impossible resolution of less than 70 nanometers, these images have made the minute structures visible which allow nerve cells to communicate with each other. This application of STED microscopy opens up numerous new possibilities for neuroscientists to decode fundamental processes in the brain. (Science, February 3, 2012)
Magnetic Resonance Imaging in real time
Real-time MRI of a human heart at a spatial resolution of 1.5 mm and a temporal resolution of 33 ms.
(http://www.biomednmr.mpg.de) [CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons.
Literature:
Shuo Zhang, Martin Uecker, Dirk Voit, Klaus-Dietmar Merboldt, and Jens Frahm, Real-time cardiac MRI at high temporal resolution: radial FLASH with nonlinear inverse reconstruction, Journal of Cardiovascular Magnetic Resonance 12:39 (2010) DOI:10.1186/1532-429X-12-39
Martin Uecker, Shuo Zhang, Dirk Voit, Alexander Karaus, Klaus-Dietmar Merboldt, and Jens Frahm, Real-time magnetic resonance imaging at a resolution of 20 ms, NMR in Biomedicine 23: 986ñ994 (2010) DOI:10.1002/nbm.1585
Real-time MRI of a human heart (2-chamber view) at 2.0 mm spatial resolution and 22 ms temporal resolution. The T1-weighted images were acquired with an RF-spoiled radial FLASH CMR sequence (TR/TE = 2.0/1.3 ms, flip angle 8°, 11 spokes) at 2.0 mm resolution, 8 mm section thickness, and 22 ms acquisition time without ECG or respiratory gating. Image reconstruction was achieved by regularized nonlinear inversion. (See: doi:10.1186/1532-429X-12-39 http://www.jcmr-online.com/content/12/1/39)
(http://www.biomednmr.mpg.de) [CC-BY-2.0 (http://creativecommons.org/licenses/by/2.0)], via Wikimedia Commons.
Literature:
Martin Uecker, Shuo Zhang, Dirk Voit, Alexander Karaus, Klaus-Dietmar Merboldt, and Jens Frahm, Real-time magnetic resonance imaging at a resolution of 20 ms, NMR in Biomedicine 23: 986ñ994 (2010) DOI:10.1002/nbm.1585
Real-time MRI of speech production at a temporal resolution of 33 ms.
(http://www.biomednmr.mpg.de) [CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons.
Literature:
Martin Uecker, Shuo Zhang, Dirk Voit, Alexander Karaus, Klaus-Dietmar Merboldt, and Jens Frahm, Real-time magnetic resonance imaging at a resolution of 20 ms, NMR in Biomedicine 23: 986-994 (2010) DOI:10.1002/nbm.1585
Real-time MRI of the knee (lateral)
(http://www.biomednmr.mpg.de) [CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons.
Literature:
Martin Uecker, Shuo Zhang, Dirk Voit, Alexander Karaus, Klaus-Dietmar Merboldt, and Jens Frahm, Real-time magnetic resonance imaging at a resolution of 20 ms, NMR in Biomedicine 23: 986ñ994 (2010) DOI:10.1002/nbm.1585