Bartels, M.; Weckbecker, D.; Kuhn, P. H.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Lichtenthaler, S. F.; Bötzel, K.; Giese, A.: Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Scientific Reports 9 (2019)
Wegrzynowicz, M.; Bar-On, D.; Calo’, L.; Anichtchik, O.; Iovino, M.; Xia, J.; Ryazanov, S.; Leonov, A.; Giese, A.; Dalley, J. W.et al.; Griesinger, C.; Ashery, U.; Spillantini, M. G.: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica (2019)
Gong, J.; Szego, E. M.; Leonov, A.; Benito, E.; Becker, S.; Fischer, A.; Zweckstetter, M.; Outeiro, T.; Schneider, A.: Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 39 (19), pp. 3752 - 3769 (2019)
Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18) (2019)
Hwang, S.; Fricke, P.; Zinke, M.; Giller, K.; Wall, J. S.; Riedel, D.; Becker, S.; Lange, A.: Comparison of the 3D structures of mouse and human alpha-synuclein fibrils by it solid-state NMR and STEM. Journal of Structural Biology 206 (1), pp. 43 - 48 (2019)
Heras‐Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy. Movement Disorders 34 (2), pp. 255 - 263 (2019)
van Maldegem, L. M.; Sansjofre, P.; Weijers, J. W. H.; Wolkenstein, K.; Strother, P. K.; Wörmer, L.; Hefter, J.; Nettersheim, B. J.; Hoshino, Y.; Schouten, S.et al.; Damsté, J. S. S.; Nath, N.; Griesinger, C.; Kuznetsov, N. B.; Elie, M.; Elvert, M.; Tegelaar, E.; Gleixner, G.; Hallmann, C.: Bisnorgammacerane traces predatory pressure and the persistent rise of algal ecosystems after Snowball Earth. Nature Communications 10 (1) (2019)
Liu, Y.; Navarro-Vázquez, A.; Gil, R. R.; Griesinger, C.; Martin, G. E.; Williamson, R. T.: Application of anisotropic NMR parameters to the confirmation of molecular structure. Nature Protocols 14 (1), pp. 217 - 247 (2019)
Wolkenstein, K.; Fuentes-Monteverde, J. C.; Nath, N.; Oji, T.; Griesinger, C.: Hypalocrinins, taurine-conjugated anthraquinone and biaryl pigments from the deep sea crinoid Hypalocrinus naresianus. Journal of Natural Products 82 (1), pp. 163 - 167 (2019)
Abayev, M.; Rodrigues, J. P. G. L. M.; Srivastava, G.; Arshava, B.; Jaremko, L.; Jaremko, M.; Naider, F.; Levitt, M.; Anglister, J.: The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5. FEBS Journal 285 (11) (2018)
Aliakbari, F.; Mohammad-Beigi, H.; Rezaei-Ghaleh, N.; Becker, S.; Esmatabad, F. D.; Seyedi, H. A. E.; Bardania, H.; Marvian, A. T.; Collingwood, J. F.; Christiansen, G.et al.; Zweckstetter, M.; Otzen, D. E.; Morshedi, D.: The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale 10 (19), pp. 9174 - 9185 (2018)
Hallwass, F.; Teles, R. R.; Hellemann , E.; Griesinger, C.; Gil, R. R.; Navarro-Vázquez, A.: Measurement of residual chemical shift anisotropies in compressed PMMA gels. Automatic compensation of gel isotropic shift contribution. Magnetic Resonance in Chemistry 56 (5), pp. 321 - 328 (2018)
Oranges, M.; Guzzi, R.; Marsh, D.; Bartucci, R.: Ether-linked lipids: Spin-label EPR and spin echoes. Chemistry and Physics of Lipids 212, pp. 130 - 137 (2018)
Reiner, A. M.; Schmidt, F.; Ryazanov, S.; Leonov, A.; Weckbecker, D.; Deeg, A. A.; Griesinger, C.; Giese, A.; Zinth, W.: Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (4), pp. 800 - 807 (2018)
Sabo, T. M.; Gapsys, V.; Walter, K. F. A.; Fenwick, R. B.; Becker, S.; Salvatella, X.; de Groot, B. L.; Lee, D.; Griesinger, C.: Utilizing dipole-dipole cross-correlated relaxation for the measurement of angles between pairs of opposing CαHα-CαHα bonds in anti-parallel β-sheets. Methods 138-139, pp. 85 - 92 (2018)
Wong, L. E.; Maier, J.; Wienands, J.; Becker, S.; Griesinger, C.: Sensitivity-enhanced Four-dimensional amide-amide correlation NMR experiments for sequential assignment of proline-rich disordered proteins. Journal of the American Chemical Society 140 (10), pp. 3518 - 3522 (2018)
Valiente-Gabioud, A. A.; Riedel, D.; Outeiro, T. F.; Menacho-Márquez, M. A.; Griesinger, C.; Fernandez, C. O.: Binding modes of phthalocyanines to amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 114 (5), pp. 1036 - 1045 (2018)
Buannic, L.; Sperrin, L.; Dervisoglu, R.; Blanc, F.; Grey, C. P.: Proton distribution in Sc-doped BaZrO3: A solid state NMR and first principle calculations analysis. Physical Chemistry Chemical Physics 20 (6), pp. 4317 - 4328 (2018)
Reddy, J. G.; Pratihar, S.; Ban, D.; Frischkorn, S.; Becker, S.; Griesinger, C.: Simultaneous determination of fast and slow dynamics in molecules using extreme CPMG relaxation dispersion experiments. Journal of Biomolecular NMR 70 (1), pp. 1 - 9 (2018)
Matthes, D.; Gapsys, V.; Griesinger, C.; de Groot, B. L.: Resolving the atomistic modes of anle138b inhibitory action on peptide oligomer formation. ACS Chemical Neuroscience 8 (12), pp. 2791 - 2808 (2017)
Reinscheid, F.; Reinscheid, U. M.: Assignment of the absolute configuration of aurantoside G and J. Journal of Molecular Structure 1147, pp. 96 - 102 (2017)
Chevelkov, V.; Giller, K.; Becker, S.; Lange, A.: Measurement of backbone hydrogen-deuterium exchange in the type III secretion system needle protein PrgI by solid-state NMR. Journal of Magnetic Resonace 283, pp. 110 - 116 (2017)
Miotto, M. C.; Pavese, M. D.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernández, C. O.: Bioinorganic chemistry of Parkinson's disease: Affinity and structural features of Cu(I) binding to the full-length β-synuclein protein. Inorganic Chemistry 56 (17), pp. 10387 - 10395 (2017)
Ban, D.; Smith, C. A.; de Groot, B. L.; Griesinger, C.; Lee, D.: Recent advances in measuring the kinetics of biomolecules by NMR relaxation dispersion spectroscopy. Archives of Biochemistry and Biophysics 628, pp. 81 - 91 (2017)
Baker, J. D.; Shelton, L. B.; Zheng, D. L.; Favretto, F.; Nordhues, B. A.; Darling, A.; Sullivan, L. E.; Sun, Z. Y.; Solanki, P. K.; Martin, M. D.et al.; Suntharalingam, A.; Sabbagh, J. J.; Becker, S.; Mandelkow, E.; Uversky, V. N.; Zweckstetter, M.; Dickey, C. A.; Koren, J.; Blair, L. J.: Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biology 15 (6) (2017)
Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J.et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25) (2017)
Haiech, J.; Heizmann, C. W.; Krebs, J.: Preface [14th International Meeting of the European Calcium Society]. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), pp. 841 - 842 (2017)
Krebs, J.: Implications of the thyroid hormone on neuronal development with special emphasis on the calmodulin-kinase IV pathway. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), pp. 877 - 882 (2017)
Nath, N.; Verma, A.; Baishya , B.; Khetrapal, C. L.: Real time band selective F-1-decoupled proton NMR for the demixing of overlay spectra of chiral molecules. Magnetic Resonance in Chemistry 55 (6), pp. 553 - 558 (2017)
Chakrabarti, K. S.; Li, J.; Das, R.; Byrd, R. A.: Conformational dynamics and allostery in E2:E3 interactions drive ubiquitination: gp78 and Ube2g2. Structure 25 (5), pp. 794 - 805 (2017)
Grohe, K.; Movellan, K. T.; Vasa, S. K.; Giller, K.; Becker, S.; Linser, R.: Non-equilibrium hydrogen exchange for determination of H-bond strength and water accessibility in solid proteins. Journal of Biomolecular NMR 68 (1), pp. 7 - 17 (2017)
França, J. A.; Navarro-Vázquez, A.; Lei, X.; Sun, H.; Griesinger, C.; Hallwass, F.: Complete NMR assignment and conformational analysis of 17-α-ethinylestradiol by using RDCs obtained in grafted graphene oxide. Magnetic Resonance in Chemistry 55 (4), pp. 297 - 303 (2017)
Salvi, M.; Schomburg, B.; Giller, K.; Graf, S.; Unden, G.; Becker, S.; Lange, A.; Griesinger, C.: Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor. Proceedings of the National Academy of Sciences of the United States of America 114 (12) (2017)
de Oliveira, R. M.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegö, E. M.; Martinho, R.; Munari, F.; Lázaro, D. F.; Moniot, S.; Guerreiro, P.et al.; Fonseca, L.; Marijanovic, Z.; Antas, P.; Gerhardt, E.; Enguita, F. J.; Fauvet, B.; Penque, D.; Pais, T. F.; Tong, Q.; Becker, S.; Kügler, S.; Lashuel, H. A.; Steegborn, C.; Zweckstetter, M.; Outeiro, T. F.: The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 15 (3) (2017)
Xiang, S.; Kulminskaya, N.; Habenstein, B.; Biernat, J.; Tepper, K.; Paulat, M.; Griesinger, C.; Becker, S.; Lange, A.; Mandelkow, E.et al.; Linser, R.: A two-component adhesive: Tau fibrils arise from a combination of a well-defined motif and conformationally flexible interactions. Journal of the American Chemical Society 139 (7), pp. 2639 - 2646 (2017)
Cramer, J.; Schiebel, J.; Wulsdorf, T.; Grohe, K.; Najbauer, E.; Ehrmann, F. R.; Radeva, N.; Zitzer, N.; Linne, U.; Linser, R.et al.; Heine, A.; Klebe, G.: A false-positive screening hit in fragment-based lead discovery: Watch out for the red herring. Angewandte Chemie International Edition 56 (7), pp. 1908 - 1913 (2017)
Franssen, W. M. J.; van Es, S. G. D.; Dervisoglu, R.; de Wijs, G. A.; Kentgens, A. P. M.: Symmetry, dynamics, and defects in methylammonium lead alide perovskites. Journal of Physical Chemistry Letters 8 (1), pp. 61 - 66 (2017)
Al-Massaedh, A.; Schmidt, M.; Pyell, U.; Reinscheid, U. M.: Elucidation of the enantiodiscrimination properties of a nonracemic chiral alignment medium through gel-based capillary electrochromatography: Separation of the mefloquine stereoisomers. ChemistryOpen 5 (5) (2016)
Pratihar, S.; Sabo, T. M.; Ban, D.; Fenwick, R. B.; Becker, S.; Salvatella, X.; Griesinger, C.; Lee, D.: Kinetics of the antibody recognition site in the third IgG-binding domain of protein G. Angewandte Chemie International Edition 128 (33), pp. 9719 - 9722 (2016)
Nath, N.; Schmidt, M.; Gil, R. B.; Williamson, R. T.; Martin, G. E.; Navarro-Vázquez, A.; Griesinger, C.; Liu, Y.: Determination of relative configuration from residual chemical shift anisotropy. Journal of the American Chemical Society 138 (30), pp. 9548 - 9556 (2016)
Fricke, P.; Mance, D.; Chevelkov, V.; Giller, K.; Becker, S.; Baldus, M.; Lange, A.: High resolution observed in 800 MHz DNP spectra of extremely rigid type III secretion needles. Journal of Biomolecular NMR 65 (3-4), pp. 121 - 126 (2016)
Akoury, E.; Mukrasch, M.; Biernat, J.; Tepper, K.; Ozenne, V.; Mandelkow, E.; Blackledge, M.; Zweckstetter, M.: Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer. Protein Science 25 (5), pp. 1010 - 1020 (2016)
Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S.; Zweckstetter, M.: Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand. Biomolecular NMR Assignments 10 (1), pp. 79 - 83 (2016)
Vasa, S. K.; Rovo, P.; Giller, K.; Becker, S.; Linser, R.: Access to aliphatic protons as reporters in non-deuterated proteins by solid-state NMR. Physical Chemistry Chemical Physics 18 (12), pp. 8359 - 8363 (2016)
Xiang, S.; Biernat, J.; Mandelkow, E.; Becker, S.; Linser, R.: Backbone assignment for minimal protein amounts of low structural homogeneity in the absence of deuteration. Chemical Communications 52 (21), pp. 4002 - 4005 (2016)
Fellner, L.; Kuzdas-Wood, D.; Levin, J.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b partly ameliorates motor deficits despite failure of neuroprotection in a model of advanced multiple system atrophy. Frontiers in Neuroscience 10 (2016)
Zong, W.; Li, G. W.; Cao, J. M.; Lei, X.; Hu, M. L.; Sun, H.; Griesinger, C.; Tan, R. X.: An alignment medium for measuring residual dipolar couplings in pure DMSO: Liquid crystals from graphene oxide grafted with polymer brushes. Angewandte Chemie-International Edition 55 (11), pp. 3690 - 3693 (2016)
Schewe, M.; Nematian-Ardestani, E.; Sun, H.; Musinszki, M.; Cordeiro, S.; Bucci, G.; de Groot, B. L.; Tucker, S. J.; Rapedius, M.; Baukrowitz, T.: A non-canonical voltage sensor controls gating in K2P K2 channels. Cell 164 (5), pp. 937 - 949 (2016)
Reinscheid, F.; Reinscheid, U. M.: Stereochemical analysis of (+)-limonene using theoretical and experimental NMR and chiroptical data. Journal of Molecular Structure 1106, pp. 141 - 153 (2016)
Reinscheid, F.; Schmidt, M.; Abromeit, H.; Liening, S.; Scriba, G. K. E.; Reinscheid, U. M.: Structural and chiroptical analysis of naturally occurring (-)-strychnine. Journal of Molecular Structure 1106, pp. 200 - 209 (2016)
Liu, L. Y.; Sun, H.; Griesinger, C.; Liu, J. K.: The use of a combination of RDC and chiroptical spectroscopy for determination of the absolute configuration of fusariumin A from the fungus Fusarium sp. Natural Products and Bioprospecting 6 (1) (2016)
Kulminskaya, N.; Vasa, S. K.; Giller, K.; Becker, S.; Kwan, A.; Sunde, M.; Linser, R.: Access to side-chain carbon information in deuterated solids under fast MAS through non-rotor-synchronized mixing. Chemical Communications 52 (2), pp. 268 - 271 (2016)
Reinscheid, U. M.; Reinscheid, F.: Stereochemical analysis of menthol and menthylamine isomers using calculated and experimental optical rotation data. Journal of Molecular Structure 1103, pp. 166 - 176 (2016)
Kuban-Jankowska, A.; Gorska, M.; Jaremko, L.; Jaremko, M.; Tuszynski, J. A.; Wozniak, M.: The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases. BioMetals 28 (6), pp. 975 - 986 (2015)
Sabo, T. M.; Trent, J. O.; Lee, D.: Population shuffling between ground and high energy excited states. Protein Science 24 (11), pp. 1714 - 1719 (2015)
Moree, B.; Yin, G.; Lazaro, D. F.; Munari, F.; Strohäker, T.; Giller, K.; Becker, S.; Outeiro, T. F.; Zweckstetter, M.; Salafsky, J.: Small molecules detected by second-harmonic generation modulate the conformation of monomeric α-synuclein and reduce its aggregation in cell. Journal of Biological Chemistry 290 (46) (2015)
Carneiro, M. G.; Reddy, J. G.; Griesinger, C.; Lee, D.: Speeding-up exchange-mediated saturation transfer experiments by Fourier transform. Journal of Biomolecular NMR 63 (3), pp. 237 - 244 (2015)
Kulminskaya, N.; Vasa, S. K.; Giller, K.; Becker, S.; Linser, R.: Asynchronous through-bond homonuclear isotropic mixing: Application to carbon-carbon transfer in perdeuterated proteins under MAS. Journal of Biomolecular NMR 63 (3), pp. 245 - 253 (2015)