Publications

Journal Article (35)

  1. Journal Article
    Fonseca-Ornelas, L.; Eisbach, S. E.; Paulat, M.; Giller, K.; Fernandez, C. O.; Outeiro, T. F.; Becker, S.; Zweckstetter, M.: Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation. Nature Communications 5 (2014)
  2. Journal Article
    Bajaj, R.; Munari, F.; Becker, S.; Zweckstetter, M.: Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes. Journal of Biological Chemistry 289 (50), pp. 34620 - 34626 (2014)
  3. Journal Article
    Miotto, M. C.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of Inorganic Biochemistry 141, pp. 208 - 211 (2014)
  4. Journal Article
    Yao, X.; Becker, S.; Zweckstetter, M.: A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 60 (4), pp. 231 - 240 (2014)
  5. Journal Article
    Parigi, G.; Rezaei-Ghaleh, N.; Giachetti, A.; Becker, S.; Fernandez, C.; Blackledge, M.; Griesinger, C.; Zweckstetter, M.; Luchinat, C.: Long-range correlated dynamics in intrinsically disordered proteins. Journal of the American Chemical Society 136 (46), pp. 16201 - 16209 (2014)
  6. Journal Article
    Yao, X.; Dürr, U. H. N.; Gattin, Z.; Laukat, Y.; Narayanan, R.L.; Brückner, A. K.; Meisinger, C.; Lange, A.; Becker, S.; Zweckstetter, M.: NMR-based detection of hydrogen/deuterium exchange in liposome-embedded membrane proteins. PLOS One 9 (11) (2014)
  7. Journal Article
    Marsh, D.: EPR moments for site-directed spin-labelling. Journal of Magnetic Resonance 248, pp. 66 - 70 (2014)
  8. Journal Article
    Xiang, S. Q.; Chevelkov, V.; Becker, S.; Lange, A.: Towards automatic protein backbone assignment using proton-detected 4D solid-state NMR data. Journal of Biomolecular NMR 60 (2-3), pp. 85 - 90 (2014)
  9. Journal Article
    Bajaj, R.; Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure 22 (10), pp. 1501 - 1511 (2014)
  10. Journal Article
    Wysoczanski, P.; Schneider, C.; Xiang, S. Q.; Munari, F.; Trowitzsch, S.; Wahl, M. C.; Lührmann, R.; Becker, S.; Zweckstetter, M.: Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 21 (10), pp. 911 - 918 (2014)
  11. Journal Article
    Yin, G.; Lopes da Fonseca, T.; Eisbach, S. E.; Anduaga, A. M.; Breda, C.; Orcellet, M. L.; Szegő, E. M.; Guerreiro, P.; Lázaro, D. F.; Braus, G. H. et al.; Fernandez, C. O.; Griesinger, C.; Becker, S.; Goody, R. S.; Itzen, A.; Giorgini, F.; Outeiro, T. F.; Zweckstetter, M.: α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease 70, pp. 149 - 161 (2014)
  12. Journal Article
    Demers, J. P.; Habenstein, B.; Loquet, A.; Vasa, S. K.; Giller, K.; Becker, S.; Baker, D.; Lange, A.; Sgourakis, N. G.: High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nature Communications 5 (2014)
  13. Journal Article
    Michielssens, S.; Peters, J. H.; Ban, D.; Pratihar, S.; Seeliger, D.; Sharma, M.; Giller, K.; Sabo, T. M.; Becker, S.; Lee, D. et al.; Griesinger, C.; de Groot, B. L.: A designed conformational shift to control protein binding specificity. Angewandte Chemie International Edition 53 (39), pp. 10367 - 10371 (2014)
  14. Journal Article
    Bartucci, R.; Guzzi, R.; Esmann, M.; Marsh, D.: Water penetration profile at the protein-lipid interface in Na,K-ATPase membranes. Biophysical Journal 107 (6), pp. 1375 - 1382 (2014)
  15. Journal Article
    Lakomek, N. A.; Kaufman, J. D.; Stahl, S. J.; Wingfield, P. T.: HIV-1 envelope protein gp41: An NMR study of dodecyl phosphocholine embedded gp41 reveals a dynamic prefusion intermediate conformation. Structure 22 (9), pp. 1311 - 1321 (2014)
  16. Journal Article
    Masini, T.; Pilger, J.; Kroezen, B. S.; Illarionov, B.; Lottmann, P.; Fischer, M.; Griesinger, C.; Hirsch, A. K. H.: De novo fragment-based design of inhibitors of DXS guided by spin-diffusion-based NMR spectroscopy. Chemical Science 5 (9), pp. 3543 - 3551 (2014)
  17. Journal Article
    Engelke, M.; Pirkuliyeva, S.; Kühn, J.; Wong, L.; Boyken, J.; Hermann, N.; Becker, S.; Griesinger, C.; Wienands, J.: Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells. Science Signaling 7 (339), ra79 (2014)
  18. Journal Article
    Lei, X.; Xu, Z.; Sun, H.; Wang, S.; Griesinger, C.; Peng, L.; Gao, C.; Tan, R. X.: Graphene oxide liquid crystals as a versatile and tunable alignment medium for the measurement of residual dipolar couplings in organic solvents. Journal of the American Chemical Society 136 (32), pp. 11280 - 11283 (2014)
  19. Journal Article
    Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Toward the functional oligomerization state of tryptophan-rich sensory proteins. Protein Science 23 (8), pp. 1154 - 1160 (2014)
  20. Journal Article
    Morin, S.; Linnet, T. E.; Lescanne, M.; Schanda, P.; Thompson, G. S.; Tollinger, M.; Teilum, K.; Gagne, S.; Marion, D.; Griesinger, C. et al.; Blackledge, M.; d'Auvergne, E. J.: relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data. Bioinformatics 30 (15), pp. 2219 - 2220 (2014)
  21. Journal Article
    Bibow, S.; Carneiro, M. G.; Sabo, T. M.; Schwiegk, C.; Becker, S.; RieK, R.; Lee, D.: Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplings. Protein Science 23 (7), pp. 851 - 856 (2014)
  22. Journal Article
    Edwards, L. J.; Savostyanov, D. V.; Welderufael, Z. T.; Lee, D.; Kuprov, I.: Quantum mechanical NMR simulation algorithm for protein-size spin systems. Journal of Magnetic Resonance 243, pp. 107 - 113 (2014)
  23. Journal Article
    Villinger, S.; Giller, K.; Bayrhuber, M.; Lange, A.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Nucleotide interactions of the human voltage-dependent anion channel. Journal of Biological Chemistry 289 (19), pp. 13397 - 13406 (2014)
  24. Journal Article
    Miotto, M. C.; Rodriguez, E. E.; Valiente-Gabioud, A. A.; Torres-Monserrat, V.; Binolfi, A.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific copper-catalyzed oxidation of alpha-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease. Inorganic Chemistry 53 (9), pp. 4350 - 4358 (2014)
  25. Journal Article
    Chevelkov, V.; Habenstein, B.; Loquet, A.; Giller, K.; Becker, S.; Lange, A.: Proton-detected MAS NMR experiments based on dipolar transfers for backbone assignment of highly deuterated proteins. Journal of Magnetic Resonance 242, pp. 180 - 188 (2014)
  26. Journal Article
    Levin, J.; Schmidt, F.; Boehm, C.; Prix, C.; Bötzel, K.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset. Acta Neuropathologica 127 (5), pp. 779 - 780 (2014)
  27. Journal Article
    Shi, C.; Fasshuber, H. K.; Chevelkov, V.; Xiang, S. Q.; Habenstein, B.; Vasa, S. K.; Becker, S.; Lange, A.: BSH-CP based 3D solid-state NMR experiments for protein resonance assignment. Journal of Biomolecular NMR 59 (1), pp. 15 - 22 (2014)
  28. Journal Article
    Sidhu, N. S.; Schreiber, K.; Pröpper, K.; Becker, S.; Usón, I.; Sheldrick, G. M.; Gärtner, J.; Krätzner, R.; Steinfeld, R.: Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Acta Crystallographica D 70 (5), pp. 1321 - 1335 (2014)
  29. Journal Article
    Rezaei-Ghaleh, N.; Amininasab, M.; Giller, K.; Kumar, S.; Stuendl, A.; Schneider, A.; Becker, S.; Walter, J.; Zweckstetter, M.: Turn plasticity distinguishes different modes of amyloid-beta aggregation. Journal of the American Chemical Society 136 (13), pp. 4913 - 4919 (2014)
  30. Journal Article
    Sabo, T. M.; Smith, C. A.; Ban, D.; Mazur, A.; Lee, D.; Griesinger, C.: ORIUM: Optimized RDC-based iterative and unified model-free analysis. Journal of Biomolecular NMR 58 (4), pp. 287 - 301 (2014)
  31. Journal Article
    Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S.; Zweckstetter, M.: Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 343 (6177), pp. 1363 - 1366 (2014)
  32. Journal Article
    Schwalbe, M.; Ozenne, V.; Bibow, S.; Jaremko, M.; Jaremko, L.; Gajda, M. J.; Jensen, M. R.; Biernat, J.; Becker, S.; Mandelkow, E. et al.; Zweckstetter, M.; Blackledge, M.: Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 22 (2), pp. 238 - 249 (2014)
  33. Journal Article
    Schmidt, M.; Reinscheid, F.; Sun, H.; Abromeit, H.; Scriba, G. K. E.; Soennichsen, F. D.; John, M.; Reinscheid, U. M.: Hidden flexibility of strychnine. European Journal of Organic Chemistry 2014 (6), pp. 1147 - 1150 (2014)
  34. Journal Article
    Thestrup, T.; Litzlbauer, J.; Bartholomaeus, I.; Mues, M.; Russo, L.; Dana, H.; Kovalchuk, Y.; Liang, Y. J.; Kalamakis, G.; Laukat, Y. et al.; Becker, S.; Witte, G.; Geiger, A.; Allen, T.; Rome, L. C.; Chen, T. W.; Kim, D. S.; Garaschuk, O.; Griesinger, C.; Griesbeck, O.: Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nature Methods 11 (2), pp. 175 - 182 (2014)
  35. Journal Article
    Kozuch, J.; Weichbrodt, C.; Millo, D.; Giller, K.; Becker, S.; Hildebrandt, P.; Steinem, C.: Voltage-dependent structural changes of the membrane-bound anion channel hVDAC1 probed by SEIRA and electrochemical impedance spectroscopy. Physical Chemistry Chemical Physics 16 (20), pp. 9546 - 9555 (2014)

Editorial (1)

  1. Editorial
    Bultynck, G.; Krebs, J.: “Ca2+ signaling and cell death”: The ECS 2013 workshop in Leuven and a tribute to Humbert De Smedt. Biochimica et Biophysica Acta-Molecular Cell Research 1843 (10), pp. 2139 - 2142 (2014)
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