Publications
Journal Article (125)
1.
Journal Article
9, e60895 (2020)
Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 2.
Journal Article
11, 4106 (2020)
Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 3.
Journal Article
39 (15), e104054 (2020)
Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 4.
Journal Article
432 (16), pp. 4369 - 4387 (2020)
Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 5.
Journal Article
48 (3), pp. 1056 - 1067 (2020)
Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 6.
Journal Article
10 (1), 97 (2020)
Cotranslational folding of proteins on the ribosome. Biomolecules 7.
Journal Article
5 (12), eaax8030 (2019)
Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 8.
Journal Article
401 (1), pp. 131 - 142 (2019)
Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 9.
Journal Article
10, 4598 (2019)
Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10.
Journal Article
593 (13), pp. 1468 - 1482 (2019)
Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 11.
Journal Article
593 (13), pp. 1483 - 1493 (2019)
The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 12.
Journal Article
5 (6), eaaw9049 (2019)
EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 13.
Journal Article
47 (10), pp. 5210 - 5222 (2019)
Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 14.
Journal Article
47 (9), pp. 4798 - 4813 (2019)
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3. Nucleic Acids Research 15.
Journal Article
47 (6), pp. 2932 - 2945 (2019)
Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 16.
Journal Article
141 (26), pp. 10236 - 10246 (2019)
Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors. Journal of the American Chemical Society 17.
Journal Article
46 (22), e130 (2018)
Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis. Nucleic Acids Research 18.
Journal Article
46 (16), pp. 8079 - 8089 (2018)
Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting. Nucleic Acids Research 19.
Journal Article
32 (17-18), pp. 1226 - 1241 (2018)
Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes and Development 20.
Journal Article
9, 3053 (2018)
Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 21.
Journal Article
8 (1), 9922 (2018)
Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 22.
Journal Article
57 (25), pp. 3460 - 3464 (2018)
Co-translational folding trajectory of the HemK helical domain. Biochemistry 23.
Journal Article
7, e34252 (2018)
Dynamics of ribosomes and release factors during translation termination in E-coli. eLife 24.
Journal Article
115 (17), pp. 4411 - 4416 (2018)
Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA. Proceedings of the National Academy of Sciences of the United States of America 25.
Journal Article
10 (9), a032664 (2018)
Translation in prokaryotes. Cold Spring Harbor Perspectives in Biology 26.
Journal Article
115 (12), pp. 3018 - 3023 (2018)
Deciphering the reading of the genetic code by near-cognate tRNA. Proceedings of the National Academy of Sciences of the United States of America 27.
Journal Article
45 (20), pp. 11858 - 11866 (2017)
Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 28.
Journal Article
68 (3), pp. 515 - 527 (2017)
Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 29.
Journal Article
20 (13), pp. 3113 - 3122 (2017)
Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 30.
Journal Article
7, 10536 (2017)
Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 31.
Journal Article
24 (9), pp. 752 - 757 (2017)
An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 32.
Journal Article
3 (6), e1700147 (2017)
Ribosome rearrangements at the onset of translational bypassing. Science Advances 33.
Journal Article
66 (4), pp. 558 - 567 (2017)
Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 34.
Journal Article
8, 15562 (2017)
Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 35.
Journal Article
139 (16), pp. 5857 - 5864 (2017)
Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 36.
Journal Article
372 (1716), 20160182 (2017)
Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 37.
Journal Article
42, pp. 83 - 89 (2017)
Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 38.
Journal Article
540 (7631), pp. 80 - 85 (2016)
The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 39.
Journal Article
35 (19), pp. 2104 - 2119 (2016)
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 40.
Journal Article
102 (1), pp. 152 - 167 (2016)
The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 41.
Journal Article
16 (8), pp. 2187 - 2196 (2016)
Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 42.
Journal Article
55 (33), pp. 9544 - 9547 (2016)
Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 43.
Journal Article
105 (8), pp. 463 - 475 (2016)
Translational GTPases. Biopolymers 44.
Journal Article
25 (8), pp. 1390 - 1406 (2016)
The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 45.
Journal Article
7, 11657 (2016)
Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 46.
Journal Article
428 (10, P. B), pp. 2165 - 2185 (2016)
Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 47.
Journal Article
113 (16), pp. E2286 - E2295 (2016)
Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 48.
Journal Article
23 (4), pp. 342 - 348 (2016)
Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 49.
Journal Article
61 (3), pp. 341 - 351 (2016)
Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 50.
Journal Article
4 (1), e1143076 (2016)
tRNA wobble modifications and protein homeostasis. Translation 51.
Journal Article
13 (12), pp. 1197 - 1203 (2016)
Translocation as continuous movement through the ribosome. RNA Biology 52.
Journal Article
43 (22), pp. 10700 - 10712 (2015)
Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 53.
Journal Article
119 (49), pp. 11820 - 11836 (2015)
Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 54.
Journal Article
21 (12), pp. 2047 - 2052 (2015)
Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 55.
Journal Article
250 (6264), pp. 1104 - 1107 (2015)
Cotranslational protein folding on the ribosome monitored in real time. Science 56.
Journal Article
137 (40), pp. 12997 - 13006 (2015)
Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 57.
Journal Article
211 (1), pp. 91 - 104 (2015)
Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 58.
Journal Article
43 (13), pp. 6426 - 6438 (2015)
Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 59.
Journal Article
6, 7442 (2015)
Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 60.
Journal Article
112 (19), pp. 6033 - 6037 (2015)
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 61.
Journal Article
40 (5), pp. 265 - 274 (2015)
Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 62.
Journal Article
520 (7548), pp. 567 - 570 (2015)
Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 63.
Journal Article
15 (5-6), pp. 862 - 879 (2015)
Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 64.
Journal Article
56 (4), pp. 531 - 540 (2014)
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 65.
Journal Article
10 (10), e1003909 (2014)
Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 66.
Journal Article
5, 5263 (2014)
Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 67.
Journal Article
111 (40), pp. 14418 - 14423 (2014)
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 68.
Journal Article
36 (10), pp. 908 - 918 (2014)
Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 69.
Journal Article
513 (7519), pp. 517 - 522 (2014)
Structural basis for the inhibition of the eukaryotic ribosome. Nature 70.
Journal Article
5, 4459 (2014)
High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 71.
Journal Article
157 (7), pp. 1619 - 1631 (2014)
Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 72.
Journal Article
5, 4180 (2014)
Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 73.
Journal Article
33 (9), pp. 1073 - 1085 (2014)
GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 74.
Journal Article
42 (3), pp. 1812 - 1820 (2014)
Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 75.
Journal Article
20 (12), pp. 1390 - 1396 (2013)
Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 76.
Journal Article
99 (11), pp. 837 - 845 (2013)
Elongation factor P: Function and effects on bacterial fitness. Biopolymers 77.
Journal Article
135 (45), pp. 17031 - 17038 (2013)
A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 78.
Journal Article
23 (4), pp. 595 - 602 (2013)
The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 79.
Journal Article
110 (30), pp. 12289 - 12294 (2013)
tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 80.
Journal Article
340 (6140), pp. 1534 - 1535 (2013)
Translocation in action. Science 81.
Journal Article
1 (1), e24315 (2013)
Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 82.
Journal Article
4, 1387 (2013)
Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nature Communications 83.
Journal Article
339 (6115), pp. 85 - 88 (2013)
EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science 84.
Journal Article
19 (12), pp. 1332 - 1337 (2012)
Dynamic switch of the signal recognition particle from scanning to targeting. Nature Structural and Molecular Biology 85.
Journal Article
18 (12), pp. 2306 - 2319 (2012)
Novel insights into the architecture and protein interaction network of yeast eIF3. RNA 86.
Journal Article
287 (33), pp. 27906 - 27912 (2012)
Thermodynamics of the GTP-GDP operated conformational switch of selenocysteine-specific translation factor SelB. Journal of Biological Chemistry 87.
Journal Article
47 (4), pp. 334 - 348 (2012)
Kinetic control of translation initiation in bacteria. Critical Reviews in Biochemistry and Molecular Biology 88.
Journal Article
40 (16), pp. 7885 - 7895 (2012)
Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation. Nucleic Acids Research 89.
Journal Article
109 (6), pp. 2102 - 2107 (2012)
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid. Proceedings of the National Academy of Sciences of the United States of America 90.
Journal Article
19 (6), pp. 609 - 615 (2012)
Real-time assembly landscape of bacterial 30S translation initiation complex. Nature Structural and Molecular Biology 91.
Journal Article
6 (12), e29525 (2011)
Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for legionella pneumophila effector glucosyltransferases. PLoS One 92.
Journal Article
366 (1580), pp. 2979 - 2986 (2011)
Evolutionary optimization of speed and accuracy of decoding on the ribosome. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 93.
Journal Article
585 (19), pp. 3073 - 3078 (2011)
The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome. FEBS Letters 94.
Journal Article
476, pp. 351 - 354 (2011)
Different substrate-dependent transition states in the active site of the ribosome. Nature 95.
Journal Article
9 (7), e1001095 (2011)
The cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biology 96.
Journal Article
286 (10), pp. 8158 - 8164 (2011)
Distortion of tRNA upon near-cognate codon recognition on the ribosome. Journal of Biological Chemistry 97.
Journal Article
39, pp. 658 - 662 (2011)
The ribosome as a molecular machine: The mechanism of tRNA–mRNA movement in translocation. Biochemical Society Transactions 98.
Journal Article
17 (4), pp. 389 - 392 (2011)
Genauigkeit und Geschwindigkeit der Proteinsynthese. Biospektrum 99.
Journal Article
29 (21), pp. 3701 - 3709 (2010)
Optimization of speed and accuracy of decoding in translation. The EMBO Journal