Publications

Journal Article (25)

  1. Journal Article
    Fard, M. K.; van der Meer, F.; Sánchez, P.; Cantuti-Castelvetri, L.; Mandad, S.; Jäkel, S.; Fornasiero, E. F.; Schmitt, S.; Ehrlich, M.; Starost, L. et al.; Kuhlmann, T.; Sergiou, C.; Schultz, V.; Wrzos, C.; Brück, W.; Urlaub, H.; Dimou, L.; Stadelmann, C.; Simons, M.: BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science Translational Medicine 9 (419) (2017)
  2. Journal Article
    Bao, P.; Will, C. L.; Urlaub, H.; Boon, K. L.; Lührmann, R.: The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development 31 (23-24), pp. 2416 - 2429 (2017)
  3. Journal Article
    Ahdash, Z.; Lau, A. M.; Byrne, R. T.; Lammens, K.; Stützer, A.; Urlaub, H.; Booth, P. J.; Reading, E.; Hopfner, K. P.; Politis, A.: Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex. Nucleic Acids Research 45 (20), pp. 12025 - 12038 (2017)
  4. Journal Article
    Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), pp. 1082 - 1093 (2017)
  5. Journal Article
    Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), pp. 204 - 209 (2017)
  6. Journal Article
    Warda, A. S.; Kretschmer, J.; Hackert, P.; Lenz, C.; Urlaub, H.; Höbartner, C.; Sloan, K. E.; Bohnsack, M. T.: Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. EMBO Reports 18 (11), pp. 2004 - 2014 (2017)
  7. Journal Article
    Scacioc, A.; Schmidt, C.; Hofmann, T.; Urlaub, H.; Kühnel, K.; Perez-Lara, A.: Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding. Scientific Reports 7 (2017)
  8. Journal Article
    Schmidt , C.; Urlaub, H.: Combining cryo-electron microscopy (cryo-EM) and cross-linking mass spectrometry (CX-MS) for structural elucidation of large protein assemblies. Current Opinion in Structural Biology 46, pp. 157 - 168 (2017)
  9. Journal Article
    Märtens, B.; Sharma, K.; Urlaub, H.; Bläsi, U.: The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus. Nucleic Acids Research 45 (15), pp. 8957 - 8967 (2017)
  10. Journal Article
    Wottawa, M.; Naas, S.; Böttger, J.; van Belle, G. J.; Möbius, W.; Revelo, N. H.; Heidenreich, D.; von Ahlen, M.; Zieseniss, A.; Kröhnert, K. et al.; Lutz, S.; Lenz, C.; Urlaub, H.; Rizzoli, S. O.; Katschinski, D. M.: Hypoxia-stimulated membrane trafficking requires T-plastin. Acta Physiologica 221 (1), pp. 59 - 73 (2017)
  11. Journal Article
    Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 170 (4), pp. 701 - 713, e1 - e4 (2017)
  12. Journal Article
    Henning, L. M.; Santos, K. F.; Sticht, J.; Jehle, S.; Lee, C. T.; Wittwer, M.; Urlaub, H.; Stelzl, U.; Wahl, M. C.; Freund, C.: A new role for FBP21 as regulator of Brr2 helicase activity. Nucleic Acids Research 45 (13), pp. 7922 - 7937 (2017)
  13. Journal Article
    Batschkus, S.; Atanassov, I.; Lenz, C.; Meyer-Marcotty, P.; Cingöz, G.; Kirschneck, C.; Urlaub, H.; Miosge, N.: Mapping the secretome of human chondrogenic progenitor cells with mass spectrometry. Annals of Anatomy 212, pp. 4 - 10 (2017)
  14. Journal Article
    Said, N.; Krupp, F.; Anedchenko, E.; Santos, K. F.; Dybkov, O.; Huang, Y. H.; Lee, C. T.; Loll, B.; Behrmann, E.; Bürger, J. et al.; Mielke, T.; Loerke, J.; Urlaub, H.; Spahn, C. M. T.; Weber, G.; Wahl, M. C.: Structural basis for λN-dependent processive transcription antitermination. Nature Microbiology 2 (7), 17062 (2017)
  15. Journal Article
    Jakhanwal, S.; Lee, C. T.; Urlaub, H.; Jahn, R.: An activated Q-SNARE/SM protein complex as a possible intermediate in SNARE assembly. EMBO Journal 36 (12), pp. 1788 - 1802 (2017)
  16. Journal Article
    Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8 (2017)
  17. Journal Article
    Treiber, T.; Treiber, N.; Plessmann, U.; Harlander, S.; Daiss, J. L.; Eichner, N.; Lehmann, G.; Schall, K.; Urlaub, H.; Meister, G.: A compendium of RNA-binding proteins that regulate microRNA biogenesis. Molecular Cell 66 (2), pp. 270 - 284 (2017)
  18. Journal Article
    Pan, K. T.; Chen, C. C.; Urlaub, H.; Khoo, K. H.: Adapting data-independent acquisition for mass spectrometry-based protein site-specific N-glycosylation analysis. Analytical Chemistry 89 (8), pp. 4532 - 4539 (2017)
  19. Journal Article
    Mohr, S.; Doebele, C.; Comoglio, F.; Berg, T.; Beck, J.; Bohnenberger, H.; Alexe, G.; Corso, J.; Ströbel, P.; Wachter, A. et al.; Beissbarth, T.; Schnutgen, F.; Cremer, A.; Haetscher, N.; Göllner, S.; Rouhi, A.; Palmqvist, L.; Rieger, M. A.; Schroeder, T.; Bönig, H.; Müller-Tidow, C.; Kuchenbauer, F.; Schütz, E.; Green, A. R.; Urlaub, H.; Stegmaier, K.; Humphries, R. K.; Serve, H.; Oellerich, T.: Hoxa9 and Meis1 cooperatively induce addiction to Syk signaling by suppressing miR-146a in acute myeloid leukemia. Cancer Cell 31 (4), pp. 549 - 562 (2017)
  20. Journal Article
    Losensky, G.; Jung, K.; Urlaub, H.; Pfeifer, F.; Fröls, S.; Lenz, C.: Shedding light on biofilm formation of Halobacterium salinarum R1 by SWATH-LC/MS/MS analysis of planktonic and sessile cells. Proteomics 17 (7), 1600111 (2017)
  21. Journal Article
    Sidarovich, A.; Will, C. L.; Anokhina, M. M.; Ceballos, J.; Sievers, S.; Agafonov, D. E.; Samatov, T.; Bao, P.; Kastner, B.; Urlaub, H. et al.; Waldmann, H.; Lührmann, R.: Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. eLife 6 (2017)
  22. Journal Article
    Bertram, K.; Agafonov, D. E.; Liu, W.; Dybkov, O.; Will, C. L.; Hartmuth, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 542 (7641), pp. 318 - 323 (2017)
  23. Journal Article
    Walter, R.; Pan, K. T.; Doebele, C.; Comoglio, F.; Tomska, K.; Bohnenberger, H.; Young, R. M.; Jacobs, L.; Keller, U.; Bönig, H. et al.; Engelke, M.; Rosenwald, A.; Urlaub, H.; Staudt, L. M.; Serve, H.; Zenz, T.; Oellerich, T.: HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B cell receptor signaling. Blood 129 (5), pp. 598 - 608 (2017)
  24. Journal Article
    Göllner, S.; Oellerich, T.; Agrawal-Singh, S.; Schenk, T.; Klein, H. U.; Rohde, C.; Pabst, C.; Sauer, T.; Lerdrup, M.; Tavor, S. et al.; Stölzel, F.; Herold, S.; Ehninger, G.; Köhler, G.; Pan, K. T.; Urlaub, H.; Serve, H.; Dugas, M.; Spiekermann, K.; Vick, B.; Jeremias, I.; Berdel, W. E.; Hansen, K.; Zelent, A.; Wickenhauser, C.; Müller, L. P.; Thiede, C.; Müller-Tidow, C.: Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nature Medicine 23 (1), pp. 69 - 78 (2017)
  25. Journal Article
    Pozzi, B.; Bragado, L.; Will, C. L.; Mammi, P.; Risso, G.; Urlaub, H.; Lührmann, R.; Srebrow, A.: SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing. Nucleic Acids Research 45 (11), pp. 6729 - 6745 (2017)
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