Publikationen
Zeitschriftenartikel (240)
1.
Zeitschriftenartikel
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Molecular Cell, In Press (2021)
2.
Zeitschriftenartikel
371 (6526), S. 305 - 309 (2021)
Structure of a transcribing RNA polymerase II–U1 snRNP complex. Science 3.
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Integrator is a genome-wide attenuator of non-productive transcription. Molecular Cell, in Press (2020)
4.
Zeitschriftenartikel
588 (7839), S. 712 - 716 (2020)
Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 5.
Zeitschriftenartikel
36, S. 1 - 34 (2020)
Structural biology of RNA polymerase II transcription: 20 years on. Annual Review of Cell and Developmental Biology 6.
Zeitschriftenartikel
30 (9), S. 1332 - 1344 (2020)
Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. Genome Research 7.
Zeitschriftenartikel
182 (4), S. 787 - 789 (2020)
Rosalind Franklin and the advent of molecular biology. Cell 8.
Zeitschriftenartikel
48 (14), S. 7712 - 7727 (2020)
CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research 9.
Zeitschriftenartikel
Permissive epigenomes endow reprogramming competence to transcriptional regulators. Nature Chemical Biology, In Press (2020)
10.
Zeitschriftenartikel
584 (7819), S. 154 - 156 (2020)
Structure of replicating SARS-CoV-2 polymerase. Nature 11.
Zeitschriftenartikel
369 (6503), S. 554 - 557 (2020)
In-cell architecture of an actively transcribing-translating expressome. Science 12.
Zeitschriftenartikel
52 (7), S. 719 - 727 (2020)
Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics 13.
Zeitschriftenartikel
52 (7), S. 655 - 661 (2020)
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nature Genetics 14.
Zeitschriftenartikel
27 (7), S. 668 - 677 (2020)
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 15.
Zeitschriftenartikel
9, e56178 (2020)
Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. eLife 16.
Zeitschriftenartikel
220, 103754 (2020)
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 17.
Zeitschriftenartikel
580 (7805), S. 669 - 672 (2020)
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 18.
Zeitschriftenartikel
579 (7799), S. 448 - 451 (2020)
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 19.
Zeitschriftenartikel
594 (2), S. 207 - 208 (2020)
500 years after the first circumnavigation of the world: The efforts, rewards and drawbacks of exploration. FEBS Letters 20.
Zeitschriftenartikel
63 (2), S. 601 - 612 (2020)
Discovery of BAY-985, a highly selective TBK1/IKK epsilon inhibitor. Journal of Medicinal Chemistry 21.
Zeitschriftenartikel
577, S. 717 - 720 (2020)
Structure of the transcription coactivator SAGA. Nature 22.
Zeitschriftenartikel
27 (1), S. 8 - 13 (2020)
Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology 23.
Zeitschriftenartikel
179 (7), S. 1537 - 1550 (2019)
Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 24.
Zeitschriftenartikel
179 (7), S. 1525 - 1536 (2019)
Structural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 25.
Zeitschriftenartikel
16, S. 1146 - 1152 (2019)
Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 26.
Zeitschriftenartikel
47 (17), S. 9282 - 9295 (2019)
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 27.
Zeitschriftenartikel
10, 3863 (2019)
Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 28.
Zeitschriftenartikel
116 (34), S. 16866 - 16871 (2019)
Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 29.
Zeitschriftenartikel
10 (1), 3603 (2019)
The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 30.
Zeitschriftenartikel
10 (1), 3138 (2019)
NASC-seq monitors RNA synthesis in single cells. Nature Communications 31.
Zeitschriftenartikel
294, S. 10663 - 10673 (2019)
Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 32.
Zeitschriftenartikel
10, 2885 (2019)
Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 33.
Zeitschriftenartikel
8, e47040 (2019)
Transcriptome maps of general eukaryotic RNA degradation factors. eLife 34.
Zeitschriftenartikel
74 (4), S. 674 - 687 (2019)
MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 35.
Zeitschriftenartikel
294 (18), S. 7528 - 7536 (2019)
Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 36.
Zeitschriftenartikel
116 (20), S. 10048 - 10057 (2019)
Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 37.
Zeitschriftenartikel
8, e45056 (2019)
Global donor and acceptor splicing site kinetics in human cells. eLife 38.
Zeitschriftenartikel
10 (1), e01966-18 (2019)
Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 39.
Zeitschriftenartikel
176 (1-2), S. 182 - 197 (2019)
The implication of early chromatin changes in X chromosome inactivation. Cell 40.
Zeitschriftenartikel
73 (1), S. 97 - 106 (2019)
Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 41.
Zeitschriftenartikel
573, S. 45 - 54 (2019)
Organization and regulation of gene transcription. Nature 42.
Zeitschriftenartikel
179 (4), S. 808 - 812 (2019)
Eukaryotic transcription turns 50. Cell 43.
Zeitschriftenartikel
9, 5432 (2018)
Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 44.
Zeitschriftenartikel
46 (21), S. 11528 - 11538 (2018)
The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 45.
Zeitschriftenartikel
562 (7728), S. 538 - 544 (2018)
Transcription factor dimerization activates the p300 acetyltransferase. Nature 46.
Zeitschriftenartikel
562 (7725), S. 76 - 81 (2018)
The interaction landscape between transcription factors and the nucleosome. Nature 47.
Zeitschriftenartikel
25 (9), S. 833 - 840 (2018)
RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 48.
Zeitschriftenartikel
25 (9), S. 754 - 765 (2018)
Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 49.
Zeitschriftenartikel
560 (7720), S. 607 - 612 (2018)
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 50.
Zeitschriftenartikel
560 (7720), S. 601 - 606 (2018)
Structure of paused transcription complex Pol II–DSIF–NELF. Nature 51.
Zeitschriftenartikel
560 (7719), S. 494 - 498 (2018)
RNA velocity of single cells. Nature 52.
Zeitschriftenartikel
293 (19), S. 7189 - 7194 (2018)
Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 53.
Zeitschriftenartikel
47, S. 425 - 446 (2018)
Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 54.
Zeitschriftenartikel
47, S. 17 - 22 (2017)
Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 55.
Zeitschriftenartikel
6, e32493 (2017)
The structure of the COPI coat determined within the cell. eLife 56.
Zeitschriftenartikel
171 (5), S. 1072 - 1081 (2017)
Structural basis of mitochondrial transcription initiation. Cell 57.
Zeitschriftenartikel
171 (5), S. 1082 - 1093 (2017)
Mechanism of transcription anti-termination in human mitochondria. Cell 58.
Zeitschriftenartikel
114 (46), S. 12172 - 12177 (2017)
Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 59.
Zeitschriftenartikel
551 (7679), S. 204 - 209 (2017)
Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 60.
Zeitschriftenartikel
23 (11), S. 1648 - 1659 (2017)
Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 61.
Zeitschriftenartikel
550 (7677), S. 539 - 542 (2017)
Nucleosome-Chd1 structure and implications for chromatin remodelling. Nature 62.
Zeitschriftenartikel
6, e29736 (2017)
CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 63.
Zeitschriftenartikel
24 (10), S. 809 - 815 (2017)
Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 64.
Zeitschriftenartikel
13 (10), e1006664 (2017)
EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 65.
Zeitschriftenartikel
429 (17), S. 2603 - 2610 (2017)
Structural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 66.
Zeitschriftenartikel
118 (7), S. 1741 - 1755 (2017)
MCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 67.
Zeitschriftenartikel
6, e26691 (2017)
9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 68.
Zeitschriftenartikel
8, 15741 (2017)
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 69.
Zeitschriftenartikel
6, e25637 (2017)
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 70.
Zeitschriftenartikel
545 (7653), S. 248 - 251 (2017)
Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 71.
Zeitschriftenartikel
356 (6334), S. 194 - 197 (2017)
Architecture of a transcribing-translating expressome. Science 72.
Zeitschriftenartikel
66 (1), S. 38 - 49 (2017)
Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 73.
Zeitschriftenartikel
66 (6), S. 77 - 88 (2017)
Spt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 74.
Zeitschriftenartikel
8, 14861 (2017)
The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 75.
Zeitschriftenartikel
169 (1), S. 120 - 131 (2017)
Structural basis of RNA polymerase I transcription initiation. Cell 76.
Zeitschriftenartikel
13 (3), 920 (2017)
TT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 77.
Zeitschriftenartikel
6, e23006 (2017)
Using the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 78.
Zeitschriftenartikel
12 (1), e0169249 (2017)
Accurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 79.
Zeitschriftenartikel
55 (52), S. 15972 - 15981 (2016)
Structural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 80.
Zeitschriftenartikel
540 (7634), S. 607 - 610 (2016)
Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 81.
Zeitschriftenartikel
113 (45), S. 12733 - 12738 (2016)
Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 82.
Zeitschriftenartikel
5, e12188 (2016)
Inference of gene regulation functions from dynamic transcriptome data. eLife 83.
Zeitschriftenartikel
291 (34), S. 17953 - 17963 (2016)
FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 84.
Zeitschriftenartikel
44 (4), S. 1177 - 1182 (2016)
Structure determination of transient transcription complexes. Biochemical Society Transactions 85.
Zeitschriftenartikel
7, 12129 (2016)
RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 86.
Zeitschriftenartikel
428 (12), S. 2569 - 2574 (2016)
Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 87.
Zeitschriftenartikel
5, e14981 (2016)
Architecture and RNA binding of the human negative elongation factor. eLife 88.
Zeitschriftenartikel
352 (6290), S. 1225 - 1228 (2016)
TT-seq maps the human transient transcriptome. Science 89.
Zeitschriftenartikel
533 (7603), S. 353 - 358 (2016)
Transcription initiation complex structures elucidate DNA opening. Nature 90.
Zeitschriftenartikel
113 (11), S. 2946 - 2951 (2016)
Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 91.
Zeitschriftenartikel
36 (5), S. 820 - 831 (2016)
Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 92.
Zeitschriftenartikel
12 (2), 857 (2016)
Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 93.
Zeitschriftenartikel
61 (2), S. 305 - 314 (2016)
Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 94.
Zeitschriftenartikel
83 (10), S. 1849 - 1858 (2015)
Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 95.
Zeitschriftenartikel
71 (9), S. 1850 - 1855 (2015)
An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 96.
Zeitschriftenartikel
58 (6), S. 1079 - 1089 (2015)
Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 97.
Zeitschriftenartikel
43 (7), S. 3726 - 3735 (2015)
A model for transcription initiation in human mitochondria. Nucleic Acids Research 98.
Zeitschriftenartikel
16 (3), S. 129 - 143 (2015)
Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 99.
Zeitschriftenartikel
518 (7539), S. 376 - 380 (2015)
Architecture of the RNA polymerase II–Mediator core initiation complex. Nature