Publikationen

2.

Zeitschriftenartikel

Maier, K. C.; Gressel, S.; Cramer, P.; Schwalb, B.: Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. Genome Research 30 (9), S. 1332 - 1344 (2020)

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3.

Zeitschriftenartikel

Cramer, P.: Rosalind Franklin and the advent of molecular biology. Cell 182 (4), S. 787 - 789 (2020)

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4.

Zeitschriftenartikel

Tellier, M.; Zaborowska, J.; Caizzi, L.; Mohammad, E.; Velychko, T.; Schwalb, B.; Ferrer-Vicens, I.; Blears, D.; Nojima, T.; Cramer, P. et al.; Murphy, S.: CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research 48 (14), S. 7712 - 7727 (2020)

MPG.PuRe

5.

Zeitschriftenartikel

Kim, K.-P.; Choi, J.; Yoon, J.; Bruder, J. M.; Shin, B.; Kim, J.; Arauzo-Bravo, M. J.; Han, D.; Wu, G.; Han, D. W. et al.; Kim, J.; Cramer, P.; Schöler, H. R.: Permissive epigenomes endow reprogramming competence to transcriptional regulators. Nature Chemical Biology, In Press (2020)

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6.

Zeitschriftenartikel

Hillen, H.; Kokic, G.; Farnung, L.; Dienemann, C.; Tegunov, D.; Cramer, P.: Structure of replicating SARS-CoV-2 polymerase. Nature 584 (7819), S. 154 - 156 (2020)

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7.

Zeitschriftenartikel

O’Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W. J. H.; Cramer, P. et al.; Stülke, J.; Mahamid, J.; Rappsilber, J.: In-cell architecture of an actively transcribing-translating expressome. Science 369 (6503), S. 554 - 557 (2020)

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8.

Zeitschriftenartikel

Jaeger, M. G.; Schwalb, B.; Mackowiak, S. D.; Velychko, T.; Hanzl, A.; Imrichova, H.; Brand, M.; Agerer, B.; Chorn, S.; Nabet, B. et al.; Ferguson, F. M.; Müller, A. C.; Bergthaler, A.; Gray, N. S.; Bradner, J. E.; Bock, C.; Hnisz, D.; Cramer, P.; Winter, G. E.: Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics 52 (7), S. 719 - 727 (2020)

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9.

Zeitschriftenartikel

Stik, G.; Vidal, E.; Barrero, M.; Cuartero, S.; Vila-Casadesús, M.; Mendieta-Esteban, J.; Tian, T. V.; Choi, J.; Berenguer, C.; Abad, A. et al.; Borsari, B.; le Dily, F.; Cramer, P.; Marti-Renom, M. A.; Stadhouders, R.; Graf, T.: CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nature Genetics 52 (7), S. 655 - 661 (2020)

MPG.PuRe

10.

Zeitschriftenartikel

Vos, S. M.; Farnung, L.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 27 (7), S. 668 - 677 (2020)

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11.

Zeitschriftenartikel

Farnung, L.; Ochmann, M.; Cramer, P.: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. eLife 9, e56178 (2020)

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pre-print

12.

Zeitschriftenartikel

Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)

MPG.PuRe

13.

Zeitschriftenartikel

Dodonova, S. O.; Zhu, F.; Dienemann, C.; Taipale, J.; Cramer, P.: Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580 (7805), S. 669 - 672 (2020)

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pre-print

14.

Zeitschriftenartikel

Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), S. 448 - 451 (2020)

MPG.PuRe

15.

Zeitschriftenartikel

Lefranc, J.; Schulze, V. K.; Hillig, R. C.; Briem, H.; Prinz, F.; Mengel, A.; Heinrich, T.; Balint, J.; Rengachari, S.; Irlbacher, H. et al.; Stockigt, D.; Bömer, U.; Bader, B.; Gradl, S. N.; Nising, C. F.; von Nussbaum, F.; Mumberg, D.; Panne, D.; Wengner, A. M.: Discovery of BAY-985, a highly selective TBK1/IKK epsilon inhibitor. Journal of Medicinal Chemistry 63 (2), S. 601 - 612 (2020)

MPG.PuRe

16.

Zeitschriftenartikel

Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, S. 717 - 720 (2020)

MPG.PuRe

17.

Zeitschriftenartikel

Wang, H.; Farnung, L.; Dienemann, C.; Cramer, P.: Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology 27 (1), S. 8 - 13 (2020)

MPG.PuRe

18.

Zeitschriftenartikel

Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), S. 1537 - 1550 (2019)

MPG.PuRe

19.

Zeitschriftenartikel

Hillen, H. S.; Bartuli, J.; Grimm, C.; Dienemann, C.; Bedenk, K.; Szalay, A. A.; Fischer, U.; Cramer, P.: Structural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 179 (7), S. 1525 - 1536 (2019)

MPG.PuRe

20.

Zeitschriftenartikel

Tegunov, D.; Cramer, P.: Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 16, S. 1146 - 1152 (2019)

MPG.PuRe

21.

Zeitschriftenartikel

Chang, C. T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 47 (17), S. 9282 - 9295 (2019)

MPG.PuRe

22.

Zeitschriftenartikel

Zhang, S.; Tischer, T.; Barford, D.: Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 10, 3863 (2019)

MPG.PuRe

23.

Zeitschriftenartikel

Mahamid, J.; Tegunov, D.; Maiser, A.; Arnold, J.; Leonhardt, H.; Plitzko, J. M.; Baumeister, W.: Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), S. 16866 - 16871 (2019)

MPG.PuRe

24.

Zeitschriftenartikel

Gressel, S.; Schwalb, B.; Cramer, P.: The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1), 3603 (2019)

MPG.PuRe

25.

Zeitschriftenartikel

Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1), 3138 (2019)

MPG.PuRe

26.

Zeitschriftenartikel

Chen, Y.; Cramer, P.: Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, S. 10663 - 10673 (2019)

MPG.PuRe

27.

Zeitschriftenartikel

Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)

MPG.PuRe

28.

Zeitschriftenartikel

Sohrabi-Jahromi, S.; Hofmann, K. B.; Boltendahl, A.; Roth, C.; Gressel, S.; Baejen, C.; Söding, J.; Cramer, P.: Transcriptome maps of general eukaryotic RNA degradation factors. eLife 8, e47040 (2019)

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29.

Zeitschriftenartikel

Baluapuri, A.; Hofstetter, J.; Dudvarski Stankovic, N.; Endres, T.; Bhandare, P.; Vos, S. M.; Adhikari, B.; Schwarz, J. D.; Narain, A.; Vogt, M. et al.; Wang, S. Y.; Düster, R.; Jung, L. A.; Vanselow, J. T.; Wiegering, A.; Geyer, M.; Maric, H. M.; Gallant, P.; Walz, S.; Schlosser, A.; Cramer, P.; Eilers, M.; Wolf, E.: MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 74 (4), S. 674 - 687 (2019)

MPG.PuRe

30.

Zeitschriftenartikel

Jones, J. L.; Hofmann, K. B.; Cowan, A. T.; Temiakov, D.; Cramer, P.; Anikin, M.: Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 294 (18), S. 7528 - 7536 (2019)

MPG.PuRe

31.

Zeitschriftenartikel

Dodonova, S. O.; Prinz, S.; Bilanchone, V.; Sandmeyer, S.; Briggs, J. A. G.: Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20), S. 10048 - 10057 (2019)

MPG.PuRe

32.

Zeitschriftenartikel

Wachutka, L.; Caizzi, L.; Gagneur, J.; Cramer, P.: Global donor and acceptor splicing site kinetics in human cells. eLife 8, e45056 (2019)

MPG.PuRe

33.

Zeitschriftenartikel

Villamizar, G. A. C.; Nacke, H.; Böhning, M.; Herz, K.; Daniel, R.: Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 10 (1), e01966-18 (2019)

MPG.PuRe

34.

Zeitschriftenartikel

Zylicz, J. J.; Bousard, A.; Zumer, K.; Dossin, F.; Mohammad, E.; da Rocha, S. T.; Schwalb, B.; Syx, L.; Dingli, F.; Loew, D. et al.; Cramer, P.; Heard, E.: The implication of early chromatin changes in X chromosome inactivation. Cell 176 (1-2), S. 182 - 197 (2019)

MPG.PuRe

35.

Zeitschriftenartikel

Dienemann, C.; Schwalb, B.; Schilbach, S.; Cramer, P.: Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 73 (1), S. 97 - 106 (2019)

MPG.PuRe

36.

Zeitschriftenartikel

Cramer, P.: Organization and regulation of gene transcription. Nature 573, S. 45 - 54 (2019)

MPG.PuRe

37.

Zeitschriftenartikel

Cramer, P.: Eukaryotic transcription turns 50. Cell 179 (4), S. 808 - 812 (2019)

MPG.PuRe

38.

Zeitschriftenartikel

Farnung, L.; Vos, S. M.; Cramer, P.: Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 9, 5432 (2018)

MPG.PuRe

39.

Zeitschriftenartikel

Lidschreiber, M.; Easter, A. D.; Battaglia, S.; Rodríguez-Molina, J. B.; Casañal, A.; Carminati, M.; Baejen, C.; Grzechnik, P.; Maier, K. C.; Cramer, P. et al.; Passmore, L. A.: The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), S. 11528 - 11538 (2018)

MPG.PuRe

40.

Zeitschriftenartikel

Ortega, E.; Rengachari, S.; Ibrahim, Z.; Hoghoughi, N.; Gaucher, J.; Holehouse, A. S.; Khochbin, S.; Panne, D.: Transcription factor dimerization activates the p300 acetyltransferase. Nature 562 (7728), S. 538 - 544 (2018)

MPG.PuRe

41.

Zeitschriftenartikel

Zhu, F.; Farnung, L.; Kaasinen, E.; Sahu, B.; Yin, Y.; Wei, B.; Dodonova, S. O.; Nitta, K. R.; Morgunova, E.; Taipale, M. et al.; Cramer, P.; Taipale, J.: The interaction landscape between transcription factors and the nucleosome. Nature 562 (7725), S. 76 - 81 (2018)

MPG.PuRe

42.

Zeitschriftenartikel

Böhning, M.; Dugast-Darzacq, C.; Rankovic, M.; Hansen, A. S.; Yu, T.; Marie-Nelly, H.; McSwiggen, D. T.; Kokic, G.; Dailey, G. M.; Cramer, P. et al.; Darzacq, X.; Zweckstetter, M.: RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), S. 833 - 840 (2018)

MPG.PuRe

43.

Zeitschriftenartikel

Hillen, H. S.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 25 (9), S. 754 - 765 (2018)

MPG.PuRe

44.

Zeitschriftenartikel

Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), S. 607 - 612 (2018)

MPG.PuRe

Full

45.

Zeitschriftenartikel

Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), S. 601 - 606 (2018)

MPG.PuRe

46.

Zeitschriftenartikel

La Manno, G.; Soldatov, R.; Zeisel, A.; Braun, E.; Hochgerner, H.; Petukhov, V.; Lidschreiber, K.; Kastriti, M. E.; Lönnerberg, P.; Furlan, A. et al.; Fan, J.; Borm, L. E.; Liu, Z.; van Bruggen, D.; Guo, J.; He, X.; Barker, R.; Sundström, E.; Castelo-Branco, G.; Cramer, P.; Adameyko, I.; Linnarsson, S.; Kharchenko, P. V.: RNA velocity of single cells. Nature 560 (7719), S. 494 - 498 (2018)

MPG.PuRe

47.

Zeitschriftenartikel

Liu, X.; Farnung, L.; Wigge, C.; Cramer, P.: Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), S. 7189 - 7194 (2018)

MPG.PuRe

48.

Zeitschriftenartikel

Engel, C.; Neyer, S.; Cramer, P.: Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, S. 425 - 446 (2018)

MPG.PuRe

49.

Zeitschriftenartikel

Hantsche, M.; Cramer, P.: Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, S. 17 - 22 (2017)

MPG.PuRe

50.

Zeitschriftenartikel

Bykov, Y. S.; Schaffer, M.; Dodonova, S. O.; Albert, S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.; Briggs, J. A. G.: The structure of the COPI coat determined within the cell. eLife 6, e32493 (2017)

MPG.PuRe

51.

Zeitschriftenartikel

Hillen, H. S.; Morozov, Y. I.; Sarfallah, A.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription initiation. Cell 171 (5), S. 1072 - 1081 (2017)

MPG.PuRe

52.

Zeitschriftenartikel

Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), S. 1082 - 1093 (2017)

MPG.PuRe

53.

Zeitschriftenartikel

Malvezzi, S.; Farnung, L.; Aloisi, C. M. N.; Angelov, T.; Cramer, P.; Sturla, S. J.: Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 114 (46), S. 12172 - 12177 (2017)

MPG.PuRe

54.

Zeitschriftenartikel

Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), S. 204 - 209 (2017)

MPG.PuRe

55.

Zeitschriftenartikel

Cheng, J.; Maier, K. C.; Avsec, Z.; Rus, P.; Gagneur, J.: Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 23 (11), S. 1648 - 1659 (2017)

MPG.PuRe

56.

Zeitschriftenartikel

Farnung, L.; Vos, S. M.; Wigge, C.; Cramer, P.: Nucleosome-Chd1 structure and implications for chromatin remodelling. Nature 550 (7677), S. 539 - 542 (2017)

MPG.PuRe

57.

Zeitschriftenartikel

Gressel, S.; Schwalb, B.; Decker, T. M.; Qin, W.; Leonhardt, H.; Eick, D.; Cramer, P.: CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6, e29736 (2017)

MPG.PuRe

58.

Zeitschriftenartikel

Bernecky, C.; Plitzko, J. M.; Cramer, P.: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 24 (10), S. 809 - 815 (2017)

MPG.PuRe

Full

59.

Zeitschriftenartikel

Glaser, L. V.; Rieger, S.; Thumann, S.; Beer, S.; Kuklik-Roos, C.; Martin, D. E.; Maier, K. C.; Harth-Hertle, M. L.; Grüning, B.; Backofen, R. et al.; Krebs, S.; Blum, H.; Zimmer, R.; Erhard, F.; Kempkes, B.: EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 13 (10), e1006664 (2017)

MPG.PuRe

60.

Zeitschriftenartikel

Cramer, P.: Structural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 429 (17), S. 2603 - 2610 (2017)

MPG.PuRe

61.

Zeitschriftenartikel

Boratyn, E.; Nowak, I.; Durbas, M.; Horwacik, I.; Sawicka, A.; Rokita, H.: MCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 118 (7), S. 1741 - 1755 (2017)

MPG.PuRe

62.

Zeitschriftenartikel

Dodonova, S. O.; Aderhold, P.; Kopp, J.; Ganeva, I.; Röhling, S.; Hagen, W. J. H.; Sinning, I.; Wieland, F.; Briggs, J. A. G.: 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6, e26691 (2017)

MPG.PuRe

63.

Zeitschriftenartikel

Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8, 15741 (2017)

MPG.PuRe

64.

Zeitschriftenartikel

Battaglia, S.; Lidschreiber, M.; Bäjen, C.; Torkler, P.; Vos, S. M.; Cramer, P.: RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6, e25637 (2017)

MPG.PuRe

65.

Zeitschriftenartikel

Nozawa, K.; Schneider, T. R.; Cramer, P.: Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 545 (7653), S. 248 - 251 (2017)

MPG.PuRe

66.

Zeitschriftenartikel

Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P.: Architecture of a transcribing-translating expressome. Science 356 (6334), S. 194 - 197 (2017)

MPG.PuRe

67.

Zeitschriftenartikel

Bäjen, C.; Andreani, J.; Torkler, P.; Battaglia, S.; Schwalb, B.; Lidschreiber, M.; Maier, K. C.; Boltendahl, A.; Rus, P.; Esslinger, S. et al.; Söding, J.; Cramer, P.: Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), S. 38 - 49 (2017)

MPG.PuRe

68.

Zeitschriftenartikel

Shetty, A.; Kallgren, S. P.; Demel, C.; Maier, K. C.; Spatt, D.; Alver, B. H.; Cramer, P.; Park, P. J.; Winston, F.: Spt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 66 (6), S. 77 - 88 (2017)

MPG.PuRe

69.

Zeitschriftenartikel

Wittmann, S.; Renner, M.; Watts, B. R.; Adams, O.; Huseyin, M.; Baejen, C.; El Omari, K.; Kilchert, C.; Heo, D. H.; Kecman, T. et al.; Cramer, P.; Grimes, J. M.; Vasiljeva, L.: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 8, 14861 (2017)

MPG.PuRe

70.

Zeitschriftenartikel

Engel, C.; Gubbey, T.; Neyer, S.; Sainsbury, S.; Oberthür, C.; Bäjen, C.; Bernecky, C.; Cramer, P.: Structural basis of RNA polymerase I transcription initiation. Cell 169 (1), S. 120 - 131 (2017)

MPG.PuRe

71.

Zeitschriftenartikel

Michel, M.; Demel, C.; Zacher, B.; Schwalb, B.; Krebs, S.; Blum, H.; Gagneur, J.; Cramer, P.: TT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 13 (3), 920 (2017)

MPG.PuRe

72.

Zeitschriftenartikel

Danev , R.; Tegunov, D.; Baumeister, W.: Using the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 6, e23006 (2017)

MPG.PuRe

73.

Zeitschriftenartikel

Zacher, B.; Michel, M.; Schwalb, B.; Cramer, P.; Tresch, A.; Gagneur, J.: Accurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 12 (1), e0169249 (2017)

MPG.PuRe

74.

Zeitschriftenartikel

Hantsche, M.; Cramer, P.: Structural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 55 (52), S. 15972 - 15981 (2016)

MPG.PuRe

75.

Zeitschriftenartikel

Neyer, S.; Kunz, M.; Geiss, C.; Hantsche, M.; Hodirnau, V. V.; Seybert, A.; Engel, C.; Scheffer, M. P.; Cramer, P.; Frangakis, A. S.: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 540 (7634), S. 607 - 610 (2016)

MPG.PuRe

76.

Zeitschriftenartikel

Fitz, V.; Shin, J.; Ehrlich, C.; Farnung, L.; Cramer, P.; Zaburdaev, V.; Grill, S. W.: Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45), S. 12733 - 12738 (2016)

MPG.PuRe

77.

Zeitschriftenartikel

Hillenbrand, P.; Maier, K. C.; Cramer, P.; Gerland, U.: Inference of gene regulation functions from dynamic transcriptome data. eLife 5, e12188 (2016)

MPG.PuRe

78.

Zeitschriftenartikel

Shao, W.; Zumer, K.; Fujinaga, K.; Peterlin, B. M.: FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), S. 17953 - 17963 (2016)

MPG.PuRe

79.

Zeitschriftenartikel

Cramer, P.: Structure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), S. 1177 - 1182 (2016)

MPG.PuRe

80.

Zeitschriftenartikel

Engel, C.; Plitzko, J.; Cramer, P.: RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7, 12129 (2016)

MPG.PuRe

81.

Zeitschriftenartikel

Plaschka, C.; Nozawa, K.; Cramer, P.: Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), S. 2569 - 2574 (2016)

MPG.PuRe

82.

Zeitschriftenartikel

Vos, S. M.; Pöllmann, D.; Caizzi, L.; Hofmann, K. B.; Rombaut, P.; Zimniak, T.; Herzog, F.; Cramer, P.: Architecture and RNA binding of the human negative elongation factor. eLife 5, e14981 (2016)

MPG.PuRe

83.

Zeitschriftenartikel

Schwalb, B.; Michel, M.; Zacher, B.; Frühauf, K.; Demel, C.; Tresch, A.; Gagneur, J.; Cramer, P.: TT-seq maps the human transient transcriptome. Science 352 (6290), S. 1225 - 1228 (2016)

MPG.PuRe

84.

Zeitschriftenartikel

Plaschka, C.; Hantsche, M.; Dienemann, C.; Burzinski, C.; Plitzko, J.; Cramer, P.: Transcription initiation complex structures elucidate DNA opening. Nature 533 (7603), S. 353 - 358 (2016)

MPG.PuRe

85.

Zeitschriftenartikel

Lisica, A.; Engel, C.; Jahnel, M.; Roldán, É.; Galburt, E. A.; Cramer, P.; Grill, S. W.: Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11), S. 2946 - 2951 (2016)

MPG.PuRe

86.

Zeitschriftenartikel

Niesser, J.; Wagner, F. R.; Kostrewa, D.; Mühlbacher, W.; Cramer, P.: Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), S. 820 - 831 (2016)

MPG.PuRe

87.

Zeitschriftenartikel

Eser, P.; Wachutka, L.; Maier, K. C.; Demel, C.; Boroni, M.; Iyer, S.; Cramer, P.; Gagneur, J.: Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2), 857 (2016)

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Schüller, R.; Forné, I.; Straub, T.; Schreieck, A.; Texier, Y.; Shah, N.; Decker, T. M.; Cramer, P.; Imhof, A.; Eick, D.: Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), S. 305 - 314 (2016)

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Mühlbacher, W.; Mayer, A.; Sun, M.; Remmert, M.; Cheung, A. C. M.; Niesser, J.; Söding, J.; Cramer, P.: Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), S. 1849 - 1858 (2015)

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Kostrewa, D.; Kuhn, C. D.; Engel, C.; Cramer, P.: An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9), S. 1850 - 1855 (2015)

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Martinez-Rucobo, F. W.; Kohler, R.; Waterbeemd, M. v. d.; Heck, A. J.; Hemann, M.; Herzog, F.; Stark, H.; Cramer, P.: Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), S. 1079 - 1089 (2015)

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Morozov, Y. I.; Parshin, A. V.; Agaronyan, K.; Cheung, A. C.; Anikin, M.; Cramer, P.; Temiakov, D.: A model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7), S. 3726 - 3735 (2015)

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Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), S. 129 - 143 (2015)

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Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), S. 376 - 380 (2015)

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Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), S. 155 - 166 (2015)

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Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12), 768 (2014)

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Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5), S. 985 - 994 (2014)

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Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), S. 745 - 757 (2014)

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Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), S. 467 - 481 (2014)

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