Publikationen
Zeitschriftenartikel (221)
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1.ZeitschriftenartikelStructure of the transcription coactivator SAGA. Nature (2020)
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2.ZeitschriftenartikelStructural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7) (2019)
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3.ZeitschriftenartikelStructural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 179 (7) (2019)
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4.ZeitschriftenartikelStructure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology (angenommen)
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5.ZeitschriftenartikelWelch award in chemistry / and also in the news. Angewandte Chemie International Edition 58 (50) (2019)
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6.ZeitschriftenartikelReal-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 16 (2019)
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7.ZeitschriftenartikelA low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 47 (17), S. 9282 - 9295 (2019)
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8.ZeitschriftenartikelCyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 10 (2019)
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9.ZeitschriftenartikelLiquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), S. 16866 - 16871 (2019)
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10.ZeitschriftenartikelThe pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1) (2019)
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11.ZeitschriftenartikelNASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1) (2019)
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12.ZeitschriftenartikelStructure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, S. 10663 - 10673 (2019)
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13.ZeitschriftenartikelStructural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10 (2019)
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14.ZeitschriftenartikelTranscriptome maps of general eukaryotic RNA degradation factors. eLife 8 (2019)
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15.ZeitschriftenartikelMYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 74 (4), S. 674 - 687 (2019)
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16.ZeitschriftenartikelYeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 294 (18), S. 7528 - 7536 (2019)
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17.ZeitschriftenartikelStructure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20) (2019)
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18.ZeitschriftenartikelGlobal donor and acceptor splicing site kinetics in human cells. eLife 8 (2019)
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19.ZeitschriftenartikelFunctional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 10 (1), e01966-18 (2019)
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20.ZeitschriftenartikelThe implication of early chromatin changes in X chromosome inactivation. Cell 176 (1-2), S. 182 - 197 (2019)
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21.ZeitschriftenartikelPromoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 73 (1), S. 97 - 106 (2019)
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22.ZeitschriftenartikelOrganization and regulation of gene transcription. Nature 573, S. 45 - 54 (2019)
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23.ZeitschriftenartikelEukaryotic transcription turns 50. Cell 179 (4), S. 808 - 812 (2019)
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24.ZeitschriftenartikelStructure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 9 (2018)
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25.ZeitschriftenartikelThe APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), S. 11528 - 11538 (2018)
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26.ZeitschriftenartikelTranscription factor dimerization activates the p300 acetyltransferase. Nature 562 (7728), S. 538 - 544 (2018)
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27.ZeitschriftenartikelThe interaction landscape between transcription factors and the nucleosome. Nature 562 (7725), S. 76 - 81 (2018)
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28.ZeitschriftenartikelRNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), S. 833 - 840 (2018)
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29.ZeitschriftenartikelStructural basis of mitochondrial transcription. Nature Structural and Molecular Biology 25 (9), S. 754 - 765 (2018)
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30.ZeitschriftenartikelStructure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), S. 601 - 606 (2018)
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31.ZeitschriftenartikelStructure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), S. 607 - 612 (2018)
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32.ZeitschriftenartikelRNA velocity of single cells. Nature 560 (7719), S. 494 - 498 (2018)
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33.ZeitschriftenartikelCryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), S. 7189 - 7194 (2018)
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34.ZeitschriftenartikelDistinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, S. 425 - 446 (2018)
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35.ZeitschriftenartikelConserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, S. 17 - 22 (2017)
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36.ZeitschriftenartikelThe structure of the COPI coat determined within the cell. eLife 6 (2017)
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37.ZeitschriftenartikelMechanism of transcription anti-termination in human mitochondria. Cell 171 (5), S. 1082 - 1093 (2017)
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38.ZeitschriftenartikelStructural basis of mitochondrial transcription initiation. Cell 171 (5), S. 1072 - 1081 (2017)
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39.ZeitschriftenartikelMechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 114 (46), S. 12172 - 12177 (2017)
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40.ZeitschriftenartikelStructures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), S. 204 - 209 (2017)
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41.ZeitschriftenartikelCis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 23 (11), S. 1648 - 1659 (2017)
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42.ZeitschriftenartikelNucleosome-Chd1 structure and implications for chromatin remodelling. Nature 550 (7677), S. 539 - 542 (2017)
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43.ZeitschriftenartikelCDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6 (2017)
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44.ZeitschriftenartikelStructure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 24 (10), S. 809 - 815 (2017)
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45.ZeitschriftenartikelEBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 13 (10), e1006664 (2017)
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46.ZeitschriftenartikelStructural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 429 (17), S. 2603 - 2610 (2017)
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47.ZeitschriftenartikelMCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 118 (7), S. 1741 - 1755 (2017)
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48.Zeitschriftenartikel9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6 (2017)
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49.ZeitschriftenartikelArchitecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8 (2017)
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50.ZeitschriftenartikelRNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6 (2017)
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51.ZeitschriftenartikelCore Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 545 (7653), S. 248 - 251 (2017)
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52.ZeitschriftenartikelArchitecture of a transcribing-translating expressome. Science 356 (6334), S. 194 - 197 (2017)
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53.ZeitschriftenartikelGenome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), S. 38 - 49 (2017)
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54.ZeitschriftenartikelSpt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 66 (6), S. 77 - 88 (2017)
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55.ZeitschriftenartikelThe conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 8 (2017)
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56.ZeitschriftenartikelStructural basis of RNA polymerase I transcription initiation. Cell 169 (1), S. 120 - 131 (2017)
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57.ZeitschriftenartikelTT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 13 (3) (2017)
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58.ZeitschriftenartikelUsing the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 6 (2017)
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59.ZeitschriftenartikelAccurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 12 (1) (2017)
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60.ZeitschriftenartikelStructural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 55 (52), S. 15972 - 15981 (2016)
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61.ZeitschriftenartikelStructure of RNA polymerase I transcribing ribosomal DNA genes. Nature 540 (7634), S. 607 - 610 (2016)
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62.ZeitschriftenartikelNucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45) (2016)
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63.ZeitschriftenartikelInference of gene regulation functions from dynamic transcriptome data. eLife 5 (2016)
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64.ZeitschriftenartikelFBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), S. 17953 - 17963 (2016)
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65.ZeitschriftenartikelStructure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), S. 1177 - 1182 (2016)
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66.ZeitschriftenartikelRNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7 (2016)
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67.ZeitschriftenartikelMediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), S. 2569 - 2574 (2016)
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68.ZeitschriftenartikelArchitecture and RNA binding of the human negative elongation factor. eLife 5 (2016)
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69.ZeitschriftenartikelTT-seq maps the human transient transcriptome. Science 352 (6290), S. 1225 - 1228 (2016)
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70.ZeitschriftenartikelTranscription initiation complex structures elucidate DNA opening. Nature 533 (7603), S. 353 - 358 (2016)
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71.ZeitschriftenartikelMechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11) (2016)
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72.ZeitschriftenartikelStructure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), S. 820 - 831 (2016)
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73.ZeitschriftenartikelDeterminants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2) (2016)
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74.ZeitschriftenartikelHeptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), S. 305 - 314 (2016)
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75.ZeitschriftenartikelStructure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), S. 1849 - 1858 (2015)
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76.ZeitschriftenartikelAn alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9) (2015)
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77.ZeitschriftenartikelMolecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), S. 1079 - 1089 (2015)
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78.ZeitschriftenartikelA model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7) (2015)
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79.ZeitschriftenartikelStructural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), S. 129 - 143 (2015)
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80.ZeitschriftenartikelArchitecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), S. 376 - 380 (2015)
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81.ZeitschriftenartikelBRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), S. 155 - 166 (2015)
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82.ZeitschriftenartikelAnnotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12) (2014)
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83.ZeitschriftenartikelA tale of chromatin and transcription in 100 structures. Cell 159 (5) (2014)
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84.ZeitschriftenartikelTranscriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), S. 745 - 757 (2014)
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85.ZeitschriftenartikelMolecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), S. 467 - 481 (2014)
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86.ZeitschriftenartikelConserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5 (2014)
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87.ZeitschriftenartikelStructure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6) (2014)
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88.ZeitschriftenartikelRpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 289 (25), S. 17446 - 17452 (2014)
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89.ZeitschriftenartikelScp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 42 (6), S. 4043 - 4055 (2014)
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90.ZeitschriftenartikelA novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 42 (6), S. 3884 - 3893 (2014)
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91.ZeitschriftenartikelRNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 21 (2), S. 175 - 179 (2014)
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92.ZeitschriftenartikelPeriodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 10 (1), 717 (2014)
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93.ZeitschriftenartikelRecruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 9 (11) (2013)
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94.ZeitschriftenartikelTranscriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155 (5) (2013)
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95.ZeitschriftenartikelThe RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 288 (51) (2013)
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96.ZeitschriftenartikelRNA polymerase I structure and transcription regulation. Nature 502 (7473) (2013)
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97.ZeitschriftenartikelGlobal analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), S. 52 - 62 (2013)
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98.ZeitschriftenartikelStructure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11) (2013)
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99.ZeitschriftenartikelStructures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 110 (38), S. 15277 - 15282 (2013)