Journal Article (215)

  1. Journal Article
    Tegunov, D.; Cramer, P.: Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 16 (2019)
  2. Journal Article
    Zhang, S.; Tischer, T.; Barford, D.: Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 10 (2019)
  3. Journal Article
    Mahamid, J.; Tegunov, D.; Maiser, A.; Arnold, J.; Leonhardt, H.; Plitzko, J. M.; Baumeister, W.: Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), pp. 16866 - 16871 (2019)
  4. Journal Article
    Gressel, S.; Schwalb, B.; Cramer, P.: The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1) (2019)
  5. Journal Article
    Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1) (2019)
  6. Journal Article
    Chen, Y.; Cramer, P.: Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, pp. 10663 - 10673 (2019)
  7. Journal Article
    Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10 (2019)
  8. Journal Article
    Sohrabi-Jahromi, S.; Hofmann, K. B.; Boltendahl, A.; Roth, C.; Gressel, S.; Baejen, C.; Söding, J.; Cramer, P.: Transcriptome maps of general eukaryotic RNA degradation factors. eLife 8 (2019)
  9. Journal Article
    Baluapuri, A.; Hofstetter, J.; Dudvarski Stankovic, N.; Endres, T.; Bhandare, P.; Vos, S. M.; Adhikari, B.; Schwarz, J. D.; Narain, A.; Vogt, M. et al.; Wang, S. Y.; Düster, R.; Jung, L. A.; Vanselow, J. T.; Wiegering, A.; Geyer, M.; Maric, H. M.; Gallant, P.; Walz, S.; Schlosser, A.; Cramer, P.; Eilers, M.; Wolf, E.: MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 74 (4), pp. 674 - 687 (2019)
  10. Journal Article
    Jones, J. L.; Hofmann, K. B.; Cowan, A. T.; Temiakov, D.; Cramer, P.; Anikin, M.: Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 294 (18), pp. 7528 - 7536 (2019)
  11. Journal Article
    Dodonova, S. O.; Prinz, S.; Bilanchone, V.; Sandmeyer, S.; Briggs, J. A. G.: Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20) (2019)
  12. Journal Article
    Wachutka, L.; Caizzi, L.; Gagneur, J.; Cramer, P.: Global donor and acceptor splicing site kinetics in human cells. eLife 8 (2019)
  13. Journal Article
    Villamizar, G. A. C.; Nacke, H.; Böhning, M.; Herz, K.; Daniel, R.: Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 10 (1), e01966-18 (2019)
  14. Journal Article
    Zylicz, J. J.; Bousard, A.; Zumer, K.; Dossin, F.; Mohammad, E.; da Rocha, S. T.; Schwalb, B.; Syx, L.; Dingli, F.; Loew, D. et al.; Cramer, P.; Heard, E.: The implication of early chromatin changes in X chromosome inactivation. Cell 176 (1-2), pp. 182 - 197 (2019)
  15. Journal Article
    Dienemann, C.; Schwalb, B.; Schilbach, S.; Cramer, P.: Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 73 (1), pp. 97 - 106 (2019)
  16. Journal Article
    Cramer, P.: Organization and regulation of gene transcription. Nature 573, pp. 45 - 54 (2019)
  17. Journal Article
    Cramer, P.: Eukaryotic transcription turns 50. Cell 179 (4), pp. 808 - 812 (2019)
  18. Journal Article
    Farnung, L.; Vos, S. M.; Cramer, P.: Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 9 (2018)
  19. Journal Article
    Lidschreiber, M.; Easter, A. D.; Battaglia, S.; Rodríguez-Molina, J. B.; Casañal, A.; Carminati, M.; Baejen, C.; Grzechnik, P.; Maier, K. C.; Cramer, P. et al.; Passmore, L. A.: The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), pp. 11528 - 11538 (2018)
  20. Journal Article
    Ortega, E.; Rengachari, S.; Ibrahim, Z.; Hoghoughi, N.; Gaucher, J.; Holehouse, A. S.; Khochbin, S.; Panne, D.: Transcription factor dimerization activates the p300 acetyltransferase. Nature 562 (7728), pp. 538 - 544 (2018)
  21. Journal Article
    Zhu, F.; Farnung, L.; Kaasinen, E.; Sahu, B.; Yin, Y.; Wei, B.; Dodonova, S. O.; Nitta, K. R.; Morgunova, E.; Taipale, M. et al.; Cramer, P.; Taipale, J.: The interaction landscape between transcription factors and the nucleosome. Nature 562 (7725), pp. 76 - 81 (2018)
  22. Journal Article
    Böhning, M.; Dugast-Darzacq, C.; Rankovic, M.; Hansen, A. S.; Yu, T.; Marie-Nelly, H.; McSwiggen, D. T.; Kokic, G.; Dailey, G. M.; Cramer, P. et al.; Darzacq, X.; Zweckstetter, M.: RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), pp. 833 - 840 (2018)
  23. Journal Article
    Hillen, H. S.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 25 (9), pp. 754 - 765 (2018)
  24. Journal Article
    Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), pp. 601 - 606 (2018)
  25. Journal Article
    Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), pp. 607 - 612 (2018)
  26. Journal Article
    La Manno, G.; Soldatov, R.; Zeisel, A.; Braun, E.; Hochgerner, H.; Petukhov, V.; Lidschreiber, K.; Kastriti, M. E.; Lönnerberg, P.; Furlan, A. et al.; Fan, J.; Borm, L. E.; Liu, Z.; van Bruggen, D.; Guo, J.; He, X.; Barker, R.; Sundström, E.; Castelo-Branco, G.; Cramer, P.; Adameyko, I.; Linnarsson, S.; Kharchenko, P. V.: RNA velocity of single cells. Nature 560 (7719), pp. 494 - 498 (2018)
  27. Journal Article
    Liu, X.; Farnung, L.; Wigge, C.; Cramer, P.: Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), pp. 7189 - 7194 (2018)
  28. Journal Article
    Engel, C.; Neyer, S.; Cramer, P.: Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, pp. 425 - 446 (2018)
  29. Journal Article
    Hantsche, M.; Cramer, P.: Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, pp. 17 - 22 (2017)
  30. Journal Article
    Bykov, Y. S.; Schaffer, M.; Dodonova, S. O.; Albert, S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.; Briggs, J. A. G.: The structure of the COPI coat determined within the cell. eLife 6 (2017)
  31. Journal Article
    Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), pp. 1082 - 1093 (2017)
  32. Journal Article
    Hillen, H. S.; Morozov, Y. I.; Sarfallah, A.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription initiation. Cell 171 (5), pp. 1072 - 1081 (2017)
  33. Journal Article
    Malvezzi, S.; Farnung, L.; Aloisi, C. M. N.; Angelov, T.; Cramer, P.; Sturla, S. J.: Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 114 (46), pp. 12172 - 12177 (2017)
  34. Journal Article
    Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), pp. 204 - 209 (2017)
  35. Journal Article
    Cheng, J.; Maier, K. C.; Avsec, Z.; Rus, P.; Gagneur, J.: Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 23 (11), pp. 1648 - 1659 (2017)
  36. Journal Article
    Farnung, L.; Vos, S. M.; Wigge, C.; Cramer, P.: Nucleosome-Chd1 structure and implications for chromatin remodelling. Nature 550 (7677), pp. 539 - 542 (2017)
  37. Journal Article
    Gressel, S.; Schwalb, B.; Decker, T. M.; Qin, W.; Leonhardt, H.; Eick, D.; Cramer, P.: CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6 (2017)
  38. Journal Article
    Bernecky, C.; Plitzko, J. M.; Cramer, P.: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 24 (10), pp. 809 - 815 (2017)
  39. Journal Article
    Glaser, L. V.; Rieger, S.; Thumann, S.; Beer, S.; Kuklik-Roos, C.; Martin, D. E.; Maier, K. C.; Harth-Hertle, M. L.; Grüning, B.; Backofen, R. et al.; Krebs, S.; Blum, H.; Zimmer, R.; Erhard, F.; Kempkes, B.: EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 13 (10), e1006664 (2017)
  40. Journal Article
    Cramer, P.: Structural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 429 (17), pp. 2603 - 2610 (2017)
  41. Journal Article
    Boratyn, E.; Nowak, I.; Durbas, M.; Horwacik, I.; Sawicka, A.; Rokita, H.: MCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 118 (7), pp. 1741 - 1755 (2017)
  42. Journal Article
    Dodonova, S. O.; Aderhold, P.; Kopp, J.; Ganeva, I.; Röhling, S.; Hagen, W. J. H.; Sinning, I.; Wieland, F.; Briggs, J. A. G.: 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6 (2017)
  43. Journal Article
    Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8 (2017)
  44. Journal Article
    Battaglia, S.; Lidschreiber, M.; Bäjen, C.; Torkler, P.; Vos, S. M.; Cramer, P.: RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6 (2017)
  45. Journal Article
    Nozawa, K.; Schneider, T. R.; Cramer, P.: Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 545 (7653), pp. 248 - 251 (2017)
  46. Journal Article
    Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P.: Architecture of a transcribing-translating expressome. Science 356 (6334), pp. 194 - 197 (2017)
  47. Journal Article
    Bäjen, C.; Andreani, J.; Torkler, P.; Battaglia, S.; Schwalb, B.; Lidschreiber, M.; Maier, K. C.; Boltendahl, A.; Rus, P.; Esslinger, S. et al.; Söding, J.; Cramer, P.: Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), pp. 38 - 49 (2017)
  48. Journal Article
    Shetty, A.; Kallgren, S. P.; Demel, C.; Maier, K. C.; Spatt, D.; Alver, B. H.; Cramer, P.; Park, P. J.; Winston, F.: Spt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 66 (6), pp. 77 - 88 (2017)
  49. Journal Article
    Wittmann, S.; Renner, M.; Watts, B. R.; Adams, O.; Huseyin, M.; Baejen, C.; El Omari, K.; Kilchert, C.; Heo, D. H.; Kecman, T. et al.; Cramer, P.; Grimes, J. M.; Vasiljeva, L.: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 8 (2017)
  50. Journal Article
    Engel, C.; Gubbey, T.; Neyer, S.; Sainsbury, S.; Oberthür, C.; Bäjen, C.; Bernecky, C.; Cramer, P.: Structural basis of RNA polymerase I transcription initiation. Cell 169 (1), pp. 120 - 131 (2017)
  51. Journal Article
    Michel, M.; Demel, C.; Zacher, B.; Schwalb, B.; Krebs, S.; Blum, H.; Gagneur, J.; Cramer, P.: TT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 13 (3) (2017)
  52. Journal Article
    Danev , R.; Tegunov, D.; Baumeister, W.: Using the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 6 (2017)
  53. Journal Article
    Zacher, B.; Michel, M.; Schwalb, B.; Cramer, P.; Tresch, A.; Gagneur, J.: Accurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 12 (1) (2017)
  54. Journal Article
    Hantsche, M.; Cramer, P.: Structural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 55 (52), pp. 15972 - 15981 (2016)
  55. Journal Article
    Neyer, S.; Kunz, M.; Geiss, C.; Hantsche, M.; Hodirnau, V. V.; Seybert, A.; Engel, C.; Scheffer, M. P.; Cramer, P.; Frangakis, A. S.: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 540 (7634), pp. 607 - 610 (2016)
  56. Journal Article
    Fitz, V.; Shin, J.; Ehrlich, C.; Farnung, L.; Cramer, P.; Zaburdaev, V.; Grill, S. W.: Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45) (2016)
  57. Journal Article
    Hillenbrand, P.; Maier, K. C.; Cramer, P.; Gerland, U.: Inference of gene regulation functions from dynamic transcriptome data. eLife 5 (2016)
  58. Journal Article
    Shao, W.; Zumer, K.; Fujinaga, K.; Peterlin, B. M.: FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), pp. 17953 - 17963 (2016)
  59. Journal Article
    Cramer, P.: Structure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), pp. 1177 - 1182 (2016)
  60. Journal Article
    Engel, C.; Plitzko, J.; Cramer, P.: RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7 (2016)
  61. Journal Article
    Plaschka, C.; Nozawa, K.; Cramer, P.: Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), pp. 2569 - 2574 (2016)
  62. Journal Article
    Vos, S. M.; Pöllmann, D.; Caizzi, L.; Hofmann, K. B.; Rombaut, P.; Zimniak, T.; Herzog, F.; Cramer, P.: Architecture and RNA binding of the human negative elongation factor. eLife 5 (2016)
  63. Journal Article
    Schwalb, B.; Michel, M.; Zacher, B.; Frühauf, K.; Demel, C.; Tresch, A.; Gagneur, J.; Cramer, P.: TT-seq maps the human transient transcriptome. Science 352 (6290), pp. 1225 - 1228 (2016)
  64. Journal Article
    Plaschka, C.; Hantsche, M.; Dienemann, C.; Burzinski, C.; Plitzko, J.; Cramer, P.: Transcription initiation complex structures elucidate DNA opening. Nature 533 (7603), pp. 353 - 358 (2016)
  65. Journal Article
    Lisica, A.; Engel, C.; Jahnel, M.; Roldán, É.; Galburt, E. A.; Cramer, P.; Grill, S. W.: Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11) (2016)
  66. Journal Article
    Niesser, J.; Wagner, F. R.; Kostrewa, D.; Mühlbacher, W.; Cramer, P.: Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), pp. 820 - 831 (2016)
  67. Journal Article
    Eser, P.; Wachutka, L.; Maier, K. C.; Demel, C.; Boroni, M.; Iyer, S.; Cramer, P.; Gagneur, J.: Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2) (2016)
  68. Journal Article
    Schüller, R.; Forné, I.; Straub, T.; Schreieck, A.; Texier, Y.; Shah, N.; Decker, T. M.; Cramer, P.; Imhof, A.; Eick, D.: Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), pp. 305 - 314 (2016)
  69. Journal Article
    Mühlbacher, W.; Mayer, A.; Sun, M.; Remmert, M.; Cheung, A. C. M.; Niesser, J.; Söding, J.; Cramer, P.: Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), pp. 1849 - 1858 (2015)
  70. Journal Article
    Kostrewa, D.; Kuhn, C. D.; Engel, C.; Cramer, P.: An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9) (2015)
  71. Journal Article
    Martinez-Rucobo, F. W.; Kohler, R.; Waterbeemd, M. v. d.; Heck, A. J.; Hemann, M.; Herzog, F.; Stark, H.; Cramer, P.: Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), pp. 1079 - 1089 (2015)
  72. Journal Article
    Morozov, Y. I.; Parshin, A. V.; Agaronyan, K.; Cheung, A. C.; Anikin, M.; Cramer, P.; Temiakov, D.: A model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7) (2015)
  73. Journal Article
    Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), pp. 129 - 143 (2015)
  74. Journal Article
    Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), pp. 376 - 380 (2015)
  75. Journal Article
    Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), pp. 155 - 166 (2015)
  76. Journal Article
    Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12) (2014)
  77. Journal Article
    Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5) (2014)
  78. Journal Article
    Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), pp. 745 - 757 (2014)
  79. Journal Article
    Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), pp. 467 - 481 (2014)
  80. Journal Article
    Mühlbacher, W.; Sainsbury, S.; Hemann, M.; Hantsche, M.; Neyer, S.; Herzog, F.; Cramer, P.: Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5 (2014)
  81. Journal Article
    Sydow, J. F.; Lipsmeier, F.; Larraillet, V.; Hilger, M.; Mautz, B.; Mølhøj, M.; Kuentzer, J.; Klostermann, S.; Schoch, J.; Voelger, H. R. et al.; Regula, J. T.; Cramer, P.; Papadimitriou, A.; Kettenberger, H.: Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6) (2014)
  82. Journal Article
    Schulz, D.; Pirkl, N.; Lehmann, E.; Cramer, P.: Rpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 289 (25), pp. 17446 - 17452 (2014)
  83. Journal Article
    Hirschmann, W. D.; Westendorf, H.; Mayer, A.; Cannarozzi, G.; Cramer, P.; Jansen, R. P.: Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 42 (6), pp. 4043 - 4055 (2014)
  84. Journal Article
    Morozov, Y. I.; Agaronyan, K.; Cheung, A. C. M.; Anikin, M.; Cramer, P.; Temiakov, D.: A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 42 (6), pp. 3884 - 3893 (2014)
  85. Journal Article
    Schreieck, A.; Easter, A. D.; Etzold, S.; Wiederhold, K.; Lidschreiber, M.; Cramer, P.; Passmore, L. A.: RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 21 (2), pp. 175 - 179 (2014)
  86. Journal Article
    Eser, P.; Demel, C.; Maier, K. C.; Schwalb, B.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 10 (1), 717 (2014)
  87. Journal Article
    Meinel, D. M.; Burkert-Kautzsch, C.; Kieser, A.; O'Duibhir, E.; Siebert, M.; Mayer, A.; Cramer, P.; Söding, J.; Holstege, F. C.; Sträßer, K.: Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 9 (11) (2013)
  88. Journal Article
    Schulz, D.; Schwalb, B.; Kiesel, A.; Baejen, C.; Torkler, P.; Gagneur, J.; Söding, J.; Cramer, P.: Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155 (5) (2013)
  89. Journal Article
    Heo, D.-h.; Yoo, I.; Kong, J.; Lidschreiber, M.; Mayer, A.; Choi, B.-Y.; Hahn, Y.; Cramer, P.; Buratowski, S.; Kim, M.: The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 288 (51) (2013)
  90. Journal Article
    Engel, C.; Sainsbury, S.; Cheung, A. C.; Kostrewa, D.; Cramer, P.: RNA polymerase I structure and transcription regulation. Nature 502 (7473) (2013)
  91. Journal Article
    Sun, M.; Schwalb, B.; Pirkl, N.; Maier, K. C.; Schenk, A.; Failmezger, H.; Tresch, A.; Cramer, P.: Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), pp. 52 - 62 (2013)
  92. Journal Article
    Schwinghammer, K.; Cheung, A. C. M.; Morozov, Y. I.; Agaronyan, K.; Temiakov, D.; Cramer, P.: Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11) (2013)
  93. Journal Article
    Kinkelin, K.; Wozniak, G. G.; Rothbart, S. B.; Lidschreiber, M.; Strahl, B. D.; Cramer, P.: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 110 (38), pp. 15277 - 15282 (2013)
  94. Journal Article
    Larivière, L.; Plaschka, C.; Seizl, M.; Petrotchenko, E. V.; Wenzeck, L.; Borchers, C. H.; Cramer, P.: Model of the Mediator middle module based on protein cross-linking. Nucleic Acids Research 41 (20) (2013)
  95. Journal Article
    Lidschreiber, M.; Leike, K.; Cramer, P.: Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Molecular and cellular biology 33 (19) (2013)
  96. Journal Article
    Fouqueau, T.; Zeller, M. E.; Cheung, A. C.; Cramer, P.; Thomm, M.: The RNA polymerase trigger loop functions in all three phases of the transcription cycle. Nucleic acids research 41 (14) (2013)
  97. Journal Article
    Michel, M.; Cramer, P.: Transitions for regulating early transcription. Cell 153 (5), pp. 943 - 944 (2013)
  98. Journal Article
    Esslinger, S. M.; Schwalb, B.; Helfer, S.; Michalik, K. M.; Witte, H.; Maier, K. C.; Martin, D.; Michalke, B.; Tresch, A.; Cramer, P. et al.; Förstemann, K.: Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. RNA Biology 10 (6) (2013)
  99. Journal Article
    Bernecky, C.; Cramer, P.: Struggling to let go: A non‐coding RNA directs its own extension and destruction. EMBO Journal 32 (6) (2013)
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