Publications

Journal Article (233)

1.
Journal Article
Osman, S.; Cramer, P.: Structural biology of RNA polymerase II transcription: 20 years on. Annual Review of Cell and Developmental Biology 36, In Press (2020)
2.
Journal Article
Maier, K. C.; Gressel, S.; Cramer, P.; Schwalb, B.: Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. Genome Research, In Press (2020)
3.
Journal Article
Cramer, P.: Rosalind Franklin and the advent of molecular biology. Cell 182 (4), pp. 787 - 789 (2020)
4.
Journal Article
Kim, K.-P.; Choi, J.; Yoon, J.; Bruder, J. M.; Shin, B.; Kim, J.; Arauzo-Bravo, M. J.; Han, D.; Wu, G.; Han, D. W. et al.; Kim, J.; Cramer, P.; Schöler, H. R.: Permissive epigenomes endow reprogramming competence to transcriptional regulators. Nature Chemical Biology, In Press (2020)
5.
Journal Article
Hillen, H.; Kokic, G.; Farnung, L.; Dienemann, C.; Tegunov, D.; Cramer, P.: Structure of replicating SARS-CoV-2 polymerase. Nature 584 (7819), pp. 154 - 156 (2020)
6.
Journal Article
O’Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W. J. H.; Cramer, P. et al.; Stülke, J.; Mahamid, J.; Rappsilber, J.: In-cell architecture of an actively transcribing-translating expressome. Science 369 (6503), pp. 554 - 557 (2020)
7.
Journal Article
Farnung, L.; Ochmann, M.; Cramer, P.: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. eLife 9, e56178 (2020)
8.
Journal Article
Stik, G.; Vidal, E.; Barrero, M.; Cuartero, S.; Vila-Casadesús, M.; Mendieta-Esteban, J.; Tian, T. V.; Choi, J.; Berenguer, C.; Abad, A. et al.; Borsari, B.; le Dily, F.; Cramer, P.; Marti-Renom, M. A.; Stadhouders, R.; Graf, T.: CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nature Genetics, In Press (2020)
9.
Journal Article
Jaeger, M. G.; Schwalb, B.; Mackowiak, S. D.; Velychko, T.; Hanzl, A.; Imrichova, H.; Brand, M.; Agerer, B.; Chorn, S.; Nabet, B. et al.; Ferguson, F. M.; Müller, A. C.; Bergthaler, A.; Gray, N. S.; Bradner, J. E.; Bock, C.; Hnisz, D.; Cramer, P.; Winter, G. E.: Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics, In Press (2020)
10.
Journal Article
Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)
11.
Journal Article
Dodonova, S. O.; Zhu, F.; Dienemann, C.; Taipale, J.; Cramer, P.: Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580 (7805), pp. 669 - 672 (2020)
12.
Journal Article
Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), pp. 448 - 451 (2020)
13.
Journal Article
Lefranc, J.; Schulze, V. K.; Hillig, R. C.; Briem, H.; Prinz, F.; Mengel, A.; Heinrich, T.; Balint, J.; Rengachari, S.; Irlbacher, H. et al.; Stockigt, D.; Bömer, U.; Bader, B.; Gradl, S. N.; Nising, C. F.; von Nussbaum, F.; Mumberg, D.; Panne, D.; Wengner, A. M.: Discovery of BAY-985, a highly selective TBK1/IKK epsilon inhibitor. Journal of Medicinal Chemistry 63 (2), pp. 601 - 612 (2020)
14.
Journal Article
Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, pp. 717 - 720 (2020)
15.
Journal Article
Wang, H.; Farnung, L.; Dienemann, C.; Cramer, P.: Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology 27 (1), pp. 8 - 13 (2020)
16.
Journal Article
Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), pp. 1537 - 1550 (2019)
17.
Journal Article
Hillen, H. S.; Bartuli, J.; Grimm, C.; Dienemann, C.; Bedenk, K.; Szalay, A. A.; Fischer, U.; Cramer, P.: Structural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 179 (7), pp. 1525 - 1536 (2019)
18.
Journal Article
Tegunov, D.; Cramer, P.: Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 16, pp. 1146 - 1152 (2019)
19.
Journal Article
Chang, C. T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 47 (17), pp. 9282 - 9295 (2019)
20.
Journal Article
Zhang, S.; Tischer, T.; Barford, D.: Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 10, 3863 (2019)
21.
Journal Article
Mahamid, J.; Tegunov, D.; Maiser, A.; Arnold, J.; Leonhardt, H.; Plitzko, J. M.; Baumeister, W.: Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), pp. 16866 - 16871 (2019)
22.
Journal Article
Gressel, S.; Schwalb, B.; Cramer, P.: The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1), 3603 (2019)
23.
Journal Article
Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1), 3138 (2019)
24.
Journal Article
Chen, Y.; Cramer, P.: Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, pp. 10663 - 10673 (2019)
25.
Journal Article
Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)
26.
Journal Article
Sohrabi-Jahromi, S.; Hofmann, K. B.; Boltendahl, A.; Roth, C.; Gressel, S.; Baejen, C.; Söding, J.; Cramer, P.: Transcriptome maps of general eukaryotic RNA degradation factors. eLife 8, e47040 (2019)
27.
Journal Article
Baluapuri, A.; Hofstetter, J.; Dudvarski Stankovic, N.; Endres, T.; Bhandare, P.; Vos, S. M.; Adhikari, B.; Schwarz, J. D.; Narain, A.; Vogt, M. et al.; Wang, S. Y.; Düster, R.; Jung, L. A.; Vanselow, J. T.; Wiegering, A.; Geyer, M.; Maric, H. M.; Gallant, P.; Walz, S.; Schlosser, A.; Cramer, P.; Eilers, M.; Wolf, E.: MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 74 (4), pp. 674 - 687 (2019)
28.
Journal Article
Jones, J. L.; Hofmann, K. B.; Cowan, A. T.; Temiakov, D.; Cramer, P.; Anikin, M.: Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 294 (18), pp. 7528 - 7536 (2019)
29.
Journal Article
Dodonova, S. O.; Prinz, S.; Bilanchone, V.; Sandmeyer, S.; Briggs, J. A. G.: Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20), pp. 10048 - 10057 (2019)
30.
Journal Article
Wachutka, L.; Caizzi, L.; Gagneur, J.; Cramer, P.: Global donor and acceptor splicing site kinetics in human cells. eLife 8, e45056 (2019)
31.
Journal Article
Villamizar, G. A. C.; Nacke, H.; Böhning, M.; Herz, K.; Daniel, R.: Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 10 (1), e01966-18 (2019)
32.
Journal Article
Zylicz, J. J.; Bousard, A.; Zumer, K.; Dossin, F.; Mohammad, E.; da Rocha, S. T.; Schwalb, B.; Syx, L.; Dingli, F.; Loew, D. et al.; Cramer, P.; Heard, E.: The implication of early chromatin changes in X chromosome inactivation. Cell 176 (1-2), pp. 182 - 197 (2019)
33.
Journal Article
Dienemann, C.; Schwalb, B.; Schilbach, S.; Cramer, P.: Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 73 (1), pp. 97 - 106 (2019)
34.
Journal Article
Cramer, P.: Organization and regulation of gene transcription. Nature 573, pp. 45 - 54 (2019)
35.
Journal Article
Cramer, P.: Eukaryotic transcription turns 50. Cell 179 (4), pp. 808 - 812 (2019)
36.
Journal Article
Farnung, L.; Vos, S. M.; Cramer, P.: Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 9, 5432 (2018)
37.
Journal Article
Lidschreiber, M.; Easter, A. D.; Battaglia, S.; Rodríguez-Molina, J. B.; Casañal, A.; Carminati, M.; Baejen, C.; Grzechnik, P.; Maier, K. C.; Cramer, P. et al.; Passmore, L. A.: The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), pp. 11528 - 11538 (2018)
38.
Journal Article
Ortega, E.; Rengachari, S.; Ibrahim, Z.; Hoghoughi, N.; Gaucher, J.; Holehouse, A. S.; Khochbin, S.; Panne, D.: Transcription factor dimerization activates the p300 acetyltransferase. Nature 562 (7728), pp. 538 - 544 (2018)
39.
Journal Article
Zhu, F.; Farnung, L.; Kaasinen, E.; Sahu, B.; Yin, Y.; Wei, B.; Dodonova, S. O.; Nitta, K. R.; Morgunova, E.; Taipale, M. et al.; Cramer, P.; Taipale, J.: The interaction landscape between transcription factors and the nucleosome. Nature 562 (7725), pp. 76 - 81 (2018)
40.
Journal Article
Böhning, M.; Dugast-Darzacq, C.; Rankovic, M.; Hansen, A. S.; Yu, T.; Marie-Nelly, H.; McSwiggen, D. T.; Kokic, G.; Dailey, G. M.; Cramer, P. et al.; Darzacq, X.; Zweckstetter, M.: RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), pp. 833 - 840 (2018)
41.
Journal Article
Hillen, H. S.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 25 (9), pp. 754 - 765 (2018)
42.
Journal Article
Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), pp. 607 - 612 (2018)
43.
Journal Article
Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), pp. 601 - 606 (2018)
44.
Journal Article
La Manno, G.; Soldatov, R.; Zeisel, A.; Braun, E.; Hochgerner, H.; Petukhov, V.; Lidschreiber, K.; Kastriti, M. E.; Lönnerberg, P.; Furlan, A. et al.; Fan, J.; Borm, L. E.; Liu, Z.; van Bruggen, D.; Guo, J.; He, X.; Barker, R.; Sundström, E.; Castelo-Branco, G.; Cramer, P.; Adameyko, I.; Linnarsson, S.; Kharchenko, P. V.: RNA velocity of single cells. Nature 560 (7719), pp. 494 - 498 (2018)
45.
Journal Article
Liu, X.; Farnung, L.; Wigge, C.; Cramer, P.: Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), pp. 7189 - 7194 (2018)
46.
Journal Article
Engel, C.; Neyer, S.; Cramer, P.: Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, pp. 425 - 446 (2018)
47.
Journal Article
Hantsche, M.; Cramer, P.: Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, pp. 17 - 22 (2017)
48.
Journal Article
Bykov, Y. S.; Schaffer, M.; Dodonova, S. O.; Albert, S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.; Briggs, J. A. G.: The structure of the COPI coat determined within the cell. eLife 6, e32493 (2017)
49.
Journal Article
Hillen, H. S.; Morozov, Y. I.; Sarfallah, A.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription initiation. Cell 171 (5), pp. 1072 - 1081 (2017)
50.
Journal Article
Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), pp. 1082 - 1093 (2017)
51.
Journal Article
Malvezzi, S.; Farnung, L.; Aloisi, C. M. N.; Angelov, T.; Cramer, P.; Sturla, S. J.: Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 114 (46), pp. 12172 - 12177 (2017)
52.
Journal Article
Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), pp. 204 - 209 (2017)
53.
Journal Article
Cheng, J.; Maier, K. C.; Avsec, Z.; Rus, P.; Gagneur, J.: Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 23 (11), pp. 1648 - 1659 (2017)
54.
Journal Article
Farnung, L.; Vos, S. M.; Wigge, C.; Cramer, P.: Nucleosome-Chd1 structure and implications for chromatin remodelling. Nature 550 (7677), pp. 539 - 542 (2017)
55.
Journal Article
Gressel, S.; Schwalb, B.; Decker, T. M.; Qin, W.; Leonhardt, H.; Eick, D.; Cramer, P.: CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6, e29736 (2017)
56.
Journal Article
Bernecky, C.; Plitzko, J. M.; Cramer, P.: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 24 (10), pp. 809 - 815 (2017)
57.
Journal Article
Glaser, L. V.; Rieger, S.; Thumann, S.; Beer, S.; Kuklik-Roos, C.; Martin, D. E.; Maier, K. C.; Harth-Hertle, M. L.; Grüning, B.; Backofen, R. et al.; Krebs, S.; Blum, H.; Zimmer, R.; Erhard, F.; Kempkes, B.: EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 13 (10), e1006664 (2017)
58.
Journal Article
Cramer, P.: Structural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 429 (17), pp. 2603 - 2610 (2017)
59.
Journal Article
Boratyn, E.; Nowak, I.; Durbas, M.; Horwacik, I.; Sawicka, A.; Rokita, H.: MCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 118 (7), pp. 1741 - 1755 (2017)
60.
Journal Article
Dodonova, S. O.; Aderhold, P.; Kopp, J.; Ganeva, I.; Röhling, S.; Hagen, W. J. H.; Sinning, I.; Wieland, F.; Briggs, J. A. G.: 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6, e26691 (2017)
61.
Journal Article
Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8, 15741 (2017)
62.
Journal Article
Battaglia, S.; Lidschreiber, M.; Bäjen, C.; Torkler, P.; Vos, S. M.; Cramer, P.: RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6, e25637 (2017)
63.
Journal Article
Nozawa, K.; Schneider, T. R.; Cramer, P.: Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 545 (7653), pp. 248 - 251 (2017)
64.
Journal Article
Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P.: Architecture of a transcribing-translating expressome. Science 356 (6334), pp. 194 - 197 (2017)
65.
Journal Article
Bäjen, C.; Andreani, J.; Torkler, P.; Battaglia, S.; Schwalb, B.; Lidschreiber, M.; Maier, K. C.; Boltendahl, A.; Rus, P.; Esslinger, S. et al.; Söding, J.; Cramer, P.: Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), pp. 38 - 49 (2017)
66.
Journal Article
Shetty, A.; Kallgren, S. P.; Demel, C.; Maier, K. C.; Spatt, D.; Alver, B. H.; Cramer, P.; Park, P. J.; Winston, F.: Spt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 66 (6), pp. 77 - 88 (2017)
67.
Journal Article
Wittmann, S.; Renner, M.; Watts, B. R.; Adams, O.; Huseyin, M.; Baejen, C.; El Omari, K.; Kilchert, C.; Heo, D. H.; Kecman, T. et al.; Cramer, P.; Grimes, J. M.; Vasiljeva, L.: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 8, 14861 (2017)
68.
Journal Article
Engel, C.; Gubbey, T.; Neyer, S.; Sainsbury, S.; Oberthür, C.; Bäjen, C.; Bernecky, C.; Cramer, P.: Structural basis of RNA polymerase I transcription initiation. Cell 169 (1), pp. 120 - 131 (2017)
69.
Journal Article
Michel, M.; Demel, C.; Zacher, B.; Schwalb, B.; Krebs, S.; Blum, H.; Gagneur, J.; Cramer, P.: TT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 13 (3), 920 (2017)
70.
Journal Article
Danev , R.; Tegunov, D.; Baumeister, W.: Using the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 6, e23006 (2017)
71.
Journal Article
Zacher, B.; Michel, M.; Schwalb, B.; Cramer, P.; Tresch, A.; Gagneur, J.: Accurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 12 (1), e0169249 (2017)
72.
Journal Article
Hantsche, M.; Cramer, P.: Structural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 55 (52), pp. 15972 - 15981 (2016)
73.
Journal Article
Neyer, S.; Kunz, M.; Geiss, C.; Hantsche, M.; Hodirnau, V. V.; Seybert, A.; Engel, C.; Scheffer, M. P.; Cramer, P.; Frangakis, A. S.: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 540 (7634), pp. 607 - 610 (2016)
74.
Journal Article
Fitz, V.; Shin, J.; Ehrlich, C.; Farnung, L.; Cramer, P.; Zaburdaev, V.; Grill, S. W.: Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45), pp. 12733 - 12738 (2016)
75.
Journal Article
Hillenbrand, P.; Maier, K. C.; Cramer, P.; Gerland, U.: Inference of gene regulation functions from dynamic transcriptome data. eLife 5, e12188 (2016)
76.
Journal Article
Shao, W.; Zumer, K.; Fujinaga, K.; Peterlin, B. M.: FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), pp. 17953 - 17963 (2016)
77.
Journal Article
Cramer, P.: Structure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), pp. 1177 - 1182 (2016)
78.
Journal Article
Engel, C.; Plitzko, J.; Cramer, P.: RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7, 12129 (2016)
79.
Journal Article
Plaschka, C.; Nozawa, K.; Cramer, P.: Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), pp. 2569 - 2574 (2016)
80.
Journal Article
Vos, S. M.; Pöllmann, D.; Caizzi, L.; Hofmann, K. B.; Rombaut, P.; Zimniak, T.; Herzog, F.; Cramer, P.: Architecture and RNA binding of the human negative elongation factor. eLife 5, e14981 (2016)
81.
Journal Article
Schwalb, B.; Michel, M.; Zacher, B.; Frühauf, K.; Demel, C.; Tresch, A.; Gagneur, J.; Cramer, P.: TT-seq maps the human transient transcriptome. Science 352 (6290), pp. 1225 - 1228 (2016)
82.
Journal Article
Plaschka, C.; Hantsche, M.; Dienemann, C.; Burzinski, C.; Plitzko, J.; Cramer, P.: Transcription initiation complex structures elucidate DNA opening. Nature 533 (7603), pp. 353 - 358 (2016)
83.
Journal Article
Lisica, A.; Engel, C.; Jahnel, M.; Roldán, É.; Galburt, E. A.; Cramer, P.; Grill, S. W.: Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11), pp. 2946 - 2951 (2016)
84.
Journal Article
Niesser, J.; Wagner, F. R.; Kostrewa, D.; Mühlbacher, W.; Cramer, P.: Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), pp. 820 - 831 (2016)
85.
Journal Article
Eser, P.; Wachutka, L.; Maier, K. C.; Demel, C.; Boroni, M.; Iyer, S.; Cramer, P.; Gagneur, J.: Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2), 857 (2016)
86.
Journal Article
Schüller, R.; Forné, I.; Straub, T.; Schreieck, A.; Texier, Y.; Shah, N.; Decker, T. M.; Cramer, P.; Imhof, A.; Eick, D.: Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), pp. 305 - 314 (2016)
87.
Journal Article
Mühlbacher, W.; Mayer, A.; Sun, M.; Remmert, M.; Cheung, A. C. M.; Niesser, J.; Söding, J.; Cramer, P.: Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), pp. 1849 - 1858 (2015)
88.
Journal Article
Kostrewa, D.; Kuhn, C. D.; Engel, C.; Cramer, P.: An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9), pp. 1850 - 1855 (2015)
89.
Journal Article
Martinez-Rucobo, F. W.; Kohler, R.; Waterbeemd, M. v. d.; Heck, A. J.; Hemann, M.; Herzog, F.; Stark, H.; Cramer, P.: Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), pp. 1079 - 1089 (2015)
90.
Journal Article
Morozov, Y. I.; Parshin, A. V.; Agaronyan, K.; Cheung, A. C.; Anikin, M.; Cramer, P.; Temiakov, D.: A model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7), pp. 3726 - 3735 (2015)
91.
Journal Article
Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), pp. 129 - 143 (2015)
92.
Journal Article
Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), pp. 376 - 380 (2015)
93.
Journal Article
Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), pp. 155 - 166 (2015)
94.
Journal Article
Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12), 768 (2014)
95.
Journal Article
Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5), pp. 985 - 994 (2014)
96.
Journal Article
Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), pp. 745 - 757 (2014)
97.
Journal Article
Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), pp. 467 - 481 (2014)
98.
Journal Article
Mühlbacher, W.; Sainsbury, S.; Hemann, M.; Hantsche, M.; Neyer, S.; Herzog, F.; Cramer, P.: Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5, 4310 (2014)
99.
Journal Article
Sydow, J. F.; Lipsmeier, F.; Larraillet, V.; Hilger, M.; Mautz, B.; Mølhøj, M.; Kuentzer, J.; Klostermann, S.; Schoch, J.; Voelger, H. R. et al.; Regula, J. T.; Cramer, P.; Papadimitriou, A.; Kettenberger, H.: Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6), e100736 (2014)
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