Publikationen

Zeitschriftenartikel (554)

  1. 1.
    MPG.PuRe
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    Strohäker, T.; Jung, B. C.; Liou, S. H.; Fernandez, C. O.; Riedel, D.; Becker, S.; Halliday, G. M.; Bennati, M.; Kim, W. S.; Lee, S. J. et al.; Zweckstetter, M.: Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts. Nature Communications 10 (2019)
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    MPG.PuRe
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    González, N.; Gentile, I.; Garro, H. A.; Delgado-Ocaña, S.; Ramunno, C. F.; Buratti, F. A.; Griesinger, C.; Fernandez, C. O.: Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: A structural and cell-based study. Journal of Biological Inorganic Chemistry 24 (8), (in press), S. 1269 - 1278 (2019)
  3. 3.
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    de Melo Sousa, C. M.; Giordani, R. B.; de Almeida, W. A. M.; Griesinger, C.; Gil, R. R.; Navarro‐Vázquez, A.; Hallwass, F.: Effect of the solvent on the conformation of monocrotaline as determined by isotropic and anisotropic NMR parameters. Magnetic Resonance in Chemistry (2019)
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    Liu, P.; Pang, B.; Dechert, S.; Zhang, X.; Andreas, L.; Fischer, S.; Meyer, F.; Zhang, K.: Physical structure selectivity of universal alkaline periodate oxidation on lignocellulose for facile Isolation of cellulose nanocrystals. Angewandte Chemie International Edition (2019)
  5. 5.
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    Wegrzynowicz, M.; Bar-On, D.; Calo’, L.; Anichtchik, O.; Iovino, M.; Xia, J.; Ryazanov, S.; Leonov, A.; Giese, A.; Dalley, J. W. et al.; Griesinger, C.; Ashery, U.; Spillantini, M. G.: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica 138 (4), S. 575 - 595 (2019)
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    Rezaei-Ghaleh, N.; Munari, F.; Becker, S.; Assfalg, M.; Griesinger, C.: A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media. Chemical Communications 55 (82) (2019)
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    Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F.; Leonov, A.; Ryazanov, S.; Griesinger, C.; Giese, A. et al.; Cauchi, R. J.; Vassallo, N.: Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin. Biochimica et Biophysica Acta. Biomembranes (2019)
  8. 8.
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    Gonzalez, N.; Arcos-Lopez, T.; König, A.; Quintanar, L.; Marquez, M. M.; Outeiro, T. F.; Fernandez, C. O.: Effects of alpha-synuclein post-translational modifications on metal binding. Journal of Neurochemistry 150 (5), S. 507 - 521 (2019)
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    Mavroeidi, P.; Arvanitaki, F.; Karakitsou, A. K.; Vetsi, M.; Kloukina, I.; Zweckstetter, M.; Giller, K.; Becker, S.; Sorrentino, Z. A.; Giasson, B. I. et al.; Jensen, P. H.; Stefanis, L.; Xilouri, M.: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica 138 (3), S. 415 - 441 (2019)
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    MPG.PuRe
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    Kaltschnee, L.; Jagtap, A.; McCormick, J.; Wagner, S.; Bouchard, L. S.; Utz, M.; Griesinger, C.; Glöggler, S.: Hyperpolarization of amino acids in water utilizing parahydrogen on a rhodium nanocatalyst. Chemistry - A European Journal 25 (47), S. 11031 - 11035 (2019)
  11. 11.
    MPG.PuRe
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    Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C.; Becker, S.; S: Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 5 (8) (2019)
  12. 12.
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    Brendel, M.; Deussing, M.; Blume, T.; Kaiser, L.; Probst, F.; Overhoff, F.; Peters, F.; von Ungern-Sternberg, B.; Ryazanov, S.; Leonov, A. et al.; Griesinger, C.; Zwergal, A.; Levin, J.; Bartenstein, P.; Yakushev, I.; Cumming, P.; Boening, G.; Ziegler, S.; Herms, J.; Giese, A.; Rominger, A.: Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research and Therapy 11 (1) (2019)
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    Hwang, S.; Öster, C.; Chevelkov, V.; Giller, K.; Lange, S.; Becker, S.; Lange, A.: Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations. Journal of Biomolecular NMR 73 (6-7), S. 281 - 291 (2019)
  14. 14.
    MPG.PuRe
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    Bartels, M.; Weckbecker, D.; Kuhn, P. H.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Lichtenthaler, S. F.; Bötzel, K.; Giese, A.: Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Scientific Reports 9 (2019)
  15. 15.
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    Gong, J.; Szego, E. M.; Leonov, A.; Benito, E.; Becker, S.; Fischer, A.; Zweckstetter, M.; Outeiro, T.; Schneider, A.: Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 39 (19), S. 3752 - 3769 (2019)
  16. 16.
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    Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18) (2019)
  17. 17.
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    Hwang, S.; Fricke, P.; Zinke, M.; Giller, K.; Wall, J. S.; Riedel, D.; Becker, S.; Lange, A.: Comparison of the 3D structures of mouse and human alpha-synuclein fibrils by it solid-state NMR and STEM. Journal of Structural Biology 206 (1), S. 43 - 48 (2019)
  18. 18.
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    Heras‐Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy. Movement Disorders 34 (2), S. 255 - 263 (2019)
  19. 19.
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    Tekwani Movellan, K.; Najbauer, E.; Pratihar, S.; Salvi, M.; Giller, K.; Becker, S.; Andreas, L. B.: Alpha protons as NMR probes in deuterated proteins. Journal of Biomolecular NMR 73 (1-2), S. 81 - 91 (2019)
  20. 20.
    MPG.PuRe
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    van Maldegem, L. M.; Sansjofre, P.; Weijers, J. W. H.; Wolkenstein, K.; Strother, P. K.; Wörmer, L.; Hefter, J.; Nettersheim, B. J.; Hoshino, Y.; Schouten, S. et al.; Damsté, J. S. S.; Nath, N.; Griesinger, C.; Kuznetsov, N. B.; Elie, M.; Elvert, M.; Tegelaar, E.; Gleixner, G.; Hallmann, C.: Bisnorgammacerane traces predatory pressure and the persistent rise of algal ecosystems after Snowball Earth. Nature Communications 10 (1) (2019)
  21. 21.
    MPG.PuRe
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    Najbauer, E.; Movellan, K. T.; Schubeis, T.; Schwarzer, T.; Castiglione, K.; Giller, K.; Pintacuda, G.; Becker, S.; Andreas, L.: Probing membrane protein insertion into lipid bilayers by solid-state NMR. ChemPhysChem 20 (2), S. 302 - 310 (2019)
  22. 22.
    MPG.PuRe
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    Ghio, S.; Camilleri, A.; Caruana, M.; Ruf, V. C.; Schmidt, F.; Leonov, A.; Ryazanov, S.; Griesinger, C.; Cauchi, R. J.; Kamp, F. et al.; Giese, A.; Vassallo, N.: Cardiolipin promotes pore-forming activity of alpha-synuclein oligomers in mitochondrial membranes. ACS Chemical Neuroscience 10 (8), S. 3815 - 3829 (2019)
  23. 23.
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    Liu, Y.; Navarro-Vázquez, A.; Gil, R. R.; Griesinger, C.; Martin, G. E.; Williamson, R. T.: Application of anisotropic NMR parameters to the confirmation of molecular structure. Nature Protocols 14 (1), S. 217 - 247 (2019)
  24. 24.
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    Wolkenstein, K.; Fuentes-Monteverde, J. C.; Nath, N.; Oji, T.; Griesinger, C.: Hypalocrinins, taurine-conjugated anthraquinone and biaryl pigments from the deep sea crinoid Hypalocrinus naresianus. Journal of Natural Products 82 (1), S. 163 - 167 (2019)
  25. 25.
    MPG.PuRe
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    Liu, H.; Pang, B.; Garces, R.; Dervisoglu, R.; Chen, L.; Andreas, L.; Zhang, K.: Helical fibers via evaporation-driven self-assembly of surface-acylated cellulose nanowhiskers. Angewandte Chemie International Edition 57 (50), S. 16323 - 16328 (2018)
  26. 26.
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    Jaipuria, G.; Giller, K.; Leonov, A.; Becker, S.; Zweckstetter, M.: Insights into cholesterol/membrane protein interactions using paramagnetic solid-state NMR. Chemistry - A European Journal 24 (66), S. 17606 - 17611 (2018)
  27. 27.
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    Rezaei-Ghaleh, N.; Parigi, G.; Soranno, A.; Holla, A.; Becker, S.; Schuler, B.; Luchinat, C.; Zweckstetter, M.: Local and global dynamics in intrinsically disordered synuclein. Angewandte Chemie International Edition 57 (46), S. 15262 - 15266 (2018)
  28. 28.
    MPG.PuRe
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    Gentile, I.; Garro, H. A.; Delgado Ocaña, S.; Gonzalez, N.; Strohäker, T.; Schibich, D.; Quintanar, L.; Sambrotta, L.; Zweckstetter, M.; Griesinger, C. et al.; Menacho Márqueza, M.; Fernandez, C. O.: Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: Binding ligands, affinity and structural features. Metallomics 10 (10), S. 1383 - 1389 (2018)
  29. 29.
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    Hwang, M. T.; Wang, Z.; Ping, J.; Ban, D. K.; Shiah, Z. C.; Antonschmidt, L.; Lee, J.; Liu, Y.; Karkisaval, A. G.; Johnson, A. T. C. et al.; Fan, C.; Glinsky, G.; Lal, R.: DNA nanotweezers and graphene transistor enable label-free genotyping. Advanced Materials 30 (34), 1802440 (2018)
  30. 30.
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    Marsh, D.: Distinct populations in spin-label EPR spectra from nitroxides. Journal of Physical Chemistry B 122 (23), S. 6129 - 6133 (2018)
  31. 31.
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    Abayev, M.; Rodrigues, J. P. G. L. M.; Srivastava, G.; Arshava, B.; Jaremko, L.; Jaremko, M.; Naider, F.; Levitt, M.; Anglister, J.: The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5. FEBS Journal 285 (11) (2018)
  32. 32.
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    Aliakbari, F.; Mohammad-Beigi, H.; Rezaei-Ghaleh, N.; Becker, S.; Esmatabad, F. D.; Seyedi, H. A. E.; Bardania, H.; Marvian, A. T.; Collingwood, J. F.; Christiansen, G. et al.; Zweckstetter, M.; Otzen, D. E.; Morshedi, D.: The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale 10 (19), S. 9174 - 9185 (2018)
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    Hallwass, F.; Teles, R. R.; Hellemann , E.; Griesinger, C.; Gil, R. R.; Navarro-Vázquez, A.: Measurement of residual chemical shift anisotropies in compressed PMMA gels. Automatic compensation of gel isotropic shift contribution. Magnetic Resonance in Chemistry 56 (5), S. 321 - 328 (2018)
  34. 34.
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    Marsh, D.: Molecular order and T1-relaxation, cross-relaxation in nitroxide spin labels. Journal of Magnetic Resonance 290, S. 38 - 45 (2018)
  35. 35.
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    Oranges, M.; Guzzi, R.; Marsh, D.; Bartucci, R.: Ether-linked lipids: Spin-label EPR and spin echoes. Chemistry and Physics of Lipids 212, S. 130 - 137 (2018)
  36. 36.
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    Pezeshkian, W.; Khandelia, H.; Marsh, D.: Lipid configurations from molecular dynamics simulations. Biophysical Journal 114 (8), S. 1895 - 1907 (2018)
  37. 37.
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    Khan, N.; Ban, D.; Trigo-Mourino, P.; Carneiro, M. G.; Konrad, M.; Lee, D.; Sabo, T. M.: 1H, 13C and 15N resonance assignment of human guanylate kinase. Biomolecular NMR Assignments 12 (1), S. 11 - 14 (2018)
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    Reiner, A. M.; Schmidt, F.; Ryazanov, S.; Leonov, A.; Weckbecker, D.; Deeg, A. A.; Griesinger, C.; Giese, A.; Zinth, W.: Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (4), S. 800 - 807 (2018)
  39. 39.
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    Sabo, T. M.; Gapsys, V.; Walter, K. F. A.; Fenwick, R. B.; Becker, S.; Salvatella, X.; de Groot, B. L.; Lee, D.; Griesinger, C.: Utilizing dipole-dipole cross-correlated relaxation for the measurement of angles between pairs of opposing CαHα-CαHα bonds in anti-parallel β-sheets. Methods 138-139, S. 85 - 92 (2018)
  40. 40.
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    Wong, L. E.; Maier, J.; Wienands, J.; Becker, S.; Griesinger, C.: Sensitivity-enhanced Four-dimensional amide-amide correlation NMR experiments for sequential assignment of proline-rich disordered proteins. Journal of the American Chemical Society 140 (10), S. 3518 - 3522 (2018)
  41. 41.
    MPG.PuRe
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    Valiente-Gabioud, A. A.; Riedel, D.; Outeiro, T. F.; Menacho-Márquez, M. A.; Griesinger, C.; Fernandez, C. O.: Binding modes of phthalocyanines to amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 114 (5), S. 1036 - 1045 (2018)
  42. 42.
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    Tolö, J.; Taschenberger, G.; Leite, K.; Stahlberg, M. A.; Spehlbrink, G.; Kues, J.; Munari, F.; Capaldi, S.; Becker, S.; Zweckstetter, M. et al.; Dean, C.; Bähr, M.; Kügler, S.: Pathophysiological consequences of neuronal alpha-Synuclein overexpression: Impacts on ion homeostasis, stress signaling, mitochondrial integrity, and electrical activity. Frontiers in Molecular Neuroscience 11 (2018)
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    Buannic, L.; Sperrin, L.; Dervisoglu, R.; Blanc, F.; Grey, C. P.: Proton distribution in Sc-doped BaZrO3: A solid state NMR and first principle calculations analysis. Physical Chemistry Chemical Physics 20 (6), S. 4317 - 4328 (2018)
  44. 44.
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    Ikeya, T.; Ban, D.; Lee, D.; Ito, Y.; Kato, K.; Griesinger, C.: Solution NMR views of dynamical ordering of biomacromolecules. Biochimica et Biophysica Acta - General Subjects 1862 (2), S. 287 - 306 (2018)
  45. 45.
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    Marsh, D.: Spin-label order parameter calibrations for slow motion. Applied Magnetic Resonance 49 (1), S. 97 - 106 (2018)
  46. 46.
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    Martinez Hernandez, A.; Urbanke, H.; Gillman, A. L.; Lee, J.; Ryazanov, S.; Agbemenyah, H. Y.; Benito, E.; Jain, G.; Kaurani, L.; Grigorian, G. et al.; Leonov, A.; Rezaei-Ghaleh, N.; Wilken, P.; Arce, F. T.; Wagner, J.; Fuhrman, M.; Caruana, M.; Camilleri, A.; Vassallo, N.; Zweckstetter, M.; Benz, R.; Giese, A.; Schneider, A.; Korte, M.; Lal, R.; Griesinger, C.; Eichele, G.; Fischer, A.: The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine 10 (1) (2018)
  47. 47.
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    Reddy, J. G.; Pratihar, S.; Ban, D.; Frischkorn, S.; Becker, S.; Griesinger, C.: Simultaneous determination of fast and slow dynamics in molecules using extreme CPMG relaxation dispersion experiments. Journal of Biomolecular NMR 70 (1), S. 1 - 9 (2018)
  48. 48.
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    Matthes, D.; Gapsys, V.; Griesinger, C.; de Groot, B. L.: Resolving the atomistic modes of anle138b inhibitory action on peptide oligomer formation. ACS Chemical Neuroscience 8 (12), S. 2791 - 2808 (2017)
  49. 49.
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    Russo, L.; Giller, K.; Pfitzner, E.; Griesinger, C.; Becker, S.: Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6. Scientific Reports 7 (2017)
  50. 50.
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    Trigo-Mourino, P.; Griesinger, C.; Lee, D.: Label-free NMR-based dissociation kinetics determination. Journal of Biomolecular NMR 69 (4), S. 229 - 235 (2017)
  51. 51.
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    Reinscheid, F.; Reinscheid, U. M.: Assignment of the absolute configuration of aurantoside G and J. Journal of Molecular Structure 1147, S. 96 - 102 (2017)
  52. 52.
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    Chevelkov, V.; Giller, K.; Becker, S.; Lange, A.: Measurement of backbone hydrogen-deuterium exchange in the type III secretion system needle protein PrgI by solid-state NMR. Journal of Magnetic Resonace 283, S. 110 - 116 (2017)
  53. 53.
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    Fonseca-Ornelas, L.; Schmidt, C. D.; Camacho-Zarco, A. R.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Small molecule-induced soluble oligomers of α-synuclein with helical structure. Chemistry. A European Journal 23 (53), S. 13010 - 13014 (2017)
  54. 54.
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    Miotto, M. C.; Pavese, M. D.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernández, C. O.: Bioinorganic chemistry of Parkinson's disease: Affinity and structural features of Cu(I) binding to the full-length β-synuclein protein. Inorganic Chemistry 56 (17), S. 10387 - 10395 (2017)
  55. 55.
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    Ban, D.; Smith, C. A.; de Groot, B. L.; Griesinger, C.; Lee, D.: Recent advances in measuring the kinetics of biomolecules by NMR relaxation dispersion spectroscopy. Archives of Biochemistry and Biophysics 628, S. 81 - 91 (2017)
  56. 56.
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    Rezaei-Ghaleh, N.; Bakhtiari, D.; Rashidi, A.: Reverse allostasis in biological systems: Minimal conditions and implications. Journal of Theoretical Biology 426, S. 134 - 139 (2017)
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    Baker, J. D.; Shelton, L. B.; Zheng, D. L.; Favretto, F.; Nordhues, B. A.; Darling, A.; Sullivan, L. E.; Sun, Z. Y.; Solanki, P. K.; Martin, M. D. et al.; Suntharalingam, A.; Sabbagh, J. J.; Becker, S.; Mandelkow, E.; Uversky, V. N.; Zweckstetter, M.; Dickey, C. A.; Koren, J.; Blair, L. J.: Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biology 15 (6) (2017)
  58. 58.
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    Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J. et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25) (2017)
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    Haiech, J.; Heizmann, C. W.; Krebs, J.: Preface [14th International Meeting of the European Calcium Society]. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), S. 841 - 842 (2017)
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    Krebs, J.: Implications of the thyroid hormone on neuronal development with special emphasis on the calmodulin-kinase IV pathway. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864 (6), S. 877 - 882 (2017)
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    Nath, N.; Verma, A.; Baishya , B.; Khetrapal, C. L.: Real time band selective F-1-decoupled proton NMR for the demixing of overlay spectra of chiral molecules. Magnetic Resonance in Chemistry 55 (6), S. 553 - 558 (2017)
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    Fredriksson, K.; Lottmann, P.; Hinz, S.; Onila, I.; Shymanets, A.; Harteneck, C.; Müller, C. E.; Griesinger, C.; Exner, T. E.: Nanodiscs for INPHARMA NMR Characterization of GPCRs: Ligand Binding to the Human A2A Adenosine Receptor. Angewandte Chemie International Edition 56 (21), S. 5750 - 5754 (2017)
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    Chakrabarti, K. S.; Li, J.; Das, R.; Byrd, R. A.: Conformational dynamics and allostery in E2:E3 interactions drive ubiquitination: gp78 and Ube2g2. Structure 25 (5), S. 794 - 805 (2017)
  64. 64.
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    Grohe, K.; Movellan, K. T.; Vasa, S. K.; Giller, K.; Becker, S.; Linser, R.: Non-equilibrium hydrogen exchange for determination of H-bond strength and water accessibility in solid proteins. Journal of Biomolecular NMR 68 (1), S. 7 - 17 (2017)
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    França, J. A.; Navarro-Vázquez, A.; Lei, X.; Sun, H.; Griesinger, C.; Hallwass, F.: Complete NMR assignment and conformational analysis of 17-α-ethinylestradiol by using RDCs obtained in grafted graphene oxide. Magnetic Resonance in Chemistry 55 (4), S. 297 - 303 (2017)
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