Publikationen
Zeitschriftenartikel (127)
1.
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Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast. Nature Communications 12, 782 (2021)
2.
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Translational control by ribosome pausing in bacteria: How a non-uniform pace of translation affects protein production and folding. Frontiers in Microbiology 11, 619430 (2021)
3.
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Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 9, e60895 (2020)
4.
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Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 11, 4106 (2020)
5.
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Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 39 (15), e104054 (2020)
6.
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Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 432 (16), S. 4369 - 4387 (2020)
7.
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Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 48 (3), S. 1056 - 1067 (2020)
8.
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Cotranslational folding of proteins on the ribosome. Biomolecules 10 (1), 97 (2020)
9.
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Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 5 (12), eaax8030 (2019)
10.
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Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 401 (1), S. 131 - 142 (2019)
11.
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Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10, 4598 (2019)
12.
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Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), S. 1468 - 1482 (2019)
13.
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The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 593 (13), S. 1483 - 1493 (2019)
14.
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EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 5 (6), eaaw9049 (2019)
15.
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Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 47 (10), S. 5210 - 5222 (2019)
16.
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Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3. Nucleic Acids Research 47 (9), S. 4798 - 4813 (2019)
17.
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Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 47 (6), S. 2932 - 2945 (2019)
18.
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Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors. Journal of the American Chemical Society 141 (26), S. 10236 - 10246 (2019)
19.
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Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis. Nucleic Acids Research 46 (22), e130 (2018)
20.
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Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting. Nucleic Acids Research 46 (16), S. 8079 - 8089 (2018)
21.
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Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes and Development 32 (17-18), S. 1226 - 1241 (2018)
22.
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Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 9, 3053 (2018)
23.
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Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 8 (1), 9922 (2018)
24.
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Co-translational folding trajectory of the HemK helical domain. Biochemistry 57 (25), S. 3460 - 3464 (2018)
25.
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Dynamics of ribosomes and release factors during translation termination in E-coli. eLife 7, e34252 (2018)
26.
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Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA. Proceedings of the National Academy of Sciences of the United States of America 115 (17), S. 4411 - 4416 (2018)
27.
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Translation in prokaryotes. Cold Spring Harbor Perspectives in Biology 10 (9), a032664 (2018)
28.
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Deciphering the reading of the genetic code by near-cognate tRNA. Proceedings of the National Academy of Sciences of the United States of America 115 (12), S. 3018 - 3023 (2018)
29.
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Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 45 (20), S. 11858 - 11866 (2017)
30.
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Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 68 (3), S. 515 - 527 (2017)
31.
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Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 20 (13), S. 3113 - 3122 (2017)
32.
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Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 7, 10536 (2017)
33.
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An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 24 (9), S. 752 - 757 (2017)
34.
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Ribosome rearrangements at the onset of translational bypassing. Science Advances 3 (6), e1700147 (2017)
35.
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Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 66 (4), S. 558 - 567 (2017)
36.
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Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 8, 15562 (2017)
37.
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Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 139 (16), S. 5857 - 5864 (2017)
38.
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Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 372 (1716), 20160182 (2017)
39.
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Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 42, S. 83 - 89 (2017)
40.
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The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 540 (7631), S. 80 - 85 (2016)
41.
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NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 35 (19), S. 2104 - 2119 (2016)
42.
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The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), S. 152 - 167 (2016)
43.
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Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 16 (8), S. 2187 - 2196 (2016)
44.
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Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 55 (33), S. 9544 - 9547 (2016)
45.
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Translational GTPases. Biopolymers 105 (8), S. 463 - 475 (2016)
46.
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The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 25 (8), S. 1390 - 1406 (2016)
47.
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Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 7, 11657 (2016)
48.
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Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 428 (10, P. B), S. 2165 - 2185 (2016)
49.
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Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 113 (16), S. E2286 - E2295 (2016)
50.
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Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 23 (4), S. 342 - 348 (2016)
51.
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Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 61 (3), S. 341 - 351 (2016)
52.
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tRNA wobble modifications and protein homeostasis. Translation 4 (1), e1143076 (2016)
53.
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Translocation as continuous movement through the ribosome. RNA Biology 13 (12), S. 1197 - 1203 (2016)
54.
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Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 43 (22), S. 10700 - 10712 (2015)
55.
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Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 119 (49), S. 11820 - 11836 (2015)
56.
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Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 21 (12), S. 2047 - 2052 (2015)
57.
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Cotranslational protein folding on the ribosome monitored in real time. Science 250 (6264), S. 1104 - 1107 (2015)
58.
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Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 137 (40), S. 12997 - 13006 (2015)
59.
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Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 211 (1), S. 91 - 104 (2015)
60.
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Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 43 (13), S. 6426 - 6438 (2015)
61.
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Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 6, 7442 (2015)
62.
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Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 112 (19), S. 6033 - 6037 (2015)
63.
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Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 40 (5), S. 265 - 274 (2015)
64.
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Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 520 (7548), S. 567 - 570 (2015)
65.
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Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 15 (5-6), S. 862 - 879 (2015)
66.
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Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 56 (4), S. 531 - 540 (2014)
67.
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Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 10 (10), e1003909 (2014)
68.
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Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 5, 5263 (2014)
69.
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Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 111 (40), S. 14418 - 14423 (2014)
70.
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Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 36 (10), S. 908 - 918 (2014)
71.
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Structural basis for the inhibition of the eukaryotic ribosome. Nature 513 (7519), S. 517 - 522 (2014)
72.
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High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 5, 4459 (2014)
73.
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Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 157 (7), S. 1619 - 1631 (2014)
74.
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Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 5, 4180 (2014)
75.
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GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 33 (9), S. 1073 - 1085 (2014)
76.
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Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 42 (3), S. 1812 - 1820 (2014)
77.
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Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), S. 1390 - 1396 (2013)
78.
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Elongation factor P: Function and effects on bacterial fitness. Biopolymers 99 (11), S. 837 - 845 (2013)
79.
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A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 135 (45), S. 17031 - 17038 (2013)
80.
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The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 23 (4), S. 595 - 602 (2013)
81.
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tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 110 (30), S. 12289 - 12294 (2013)
82.
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Translocation in action. Science 340 (6140), S. 1534 - 1535 (2013)
83.
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Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 1 (1), e24315 (2013)
84.
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Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nature Communications 4, 1387 (2013)
85.
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EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science 339 (6115), S. 85 - 88 (2013)
86.
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Dynamic switch of the signal recognition particle from scanning to targeting. Nature Structural and Molecular Biology 19 (12), S. 1332 - 1337 (2012)
87.
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Novel insights into the architecture and protein interaction network of yeast eIF3. RNA 18 (12), S. 2306 - 2319 (2012)
88.
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Thermodynamics of the GTP-GDP operated conformational switch of selenocysteine-specific translation factor SelB. Journal of Biological Chemistry 287 (33), S. 27906 - 27912 (2012)
89.
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Kinetic control of translation initiation in bacteria. Critical Reviews in Biochemistry and Molecular Biology 47 (4), S. 334 - 348 (2012)
90.
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Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation. Nucleic Acids Research 40 (16), S. 7885 - 7895 (2012)
91.
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Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid. Proceedings of the National Academy of Sciences of the United States of America 109 (6), S. 2102 - 2107 (2012)
92.
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Real-time assembly landscape of bacterial 30S translation initiation complex. Nature Structural and Molecular Biology 19 (6), S. 609 - 615 (2012)
93.
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Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for legionella pneumophila effector glucosyltransferases. PLoS One 6 (12), e29525 (2011)
94.
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Evolutionary optimization of speed and accuracy of decoding on the ribosome. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 366 (1580), S. 2979 - 2986 (2011)
95.
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The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome. FEBS Letters 585 (19), S. 3073 - 3078 (2011)
96.
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Different substrate-dependent transition states in the active site of the ribosome. Nature 476, S. 351 - 354 (2011)
97.
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The cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biology 9 (7), e1001095 (2011)
98.
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Distortion of tRNA upon near-cognate codon recognition on the ribosome. Journal of Biological Chemistry 286 (10), S. 8158 - 8164 (2011)
99.
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The ribosome as a molecular machine: The mechanism of tRNA–mRNA movement in translocation. Biochemical Society Transactions 39, S. 658 - 662 (2011)