Publikationen
Zeitschriftenartikel (125)
1.
Zeitschriftenartikel
9, e60895 (2020)
Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 2.
Zeitschriftenartikel
11, 4106 (2020)
Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 3.
Zeitschriftenartikel
39 (15), e104054 (2020)
Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 4.
Zeitschriftenartikel
432 (16), S. 4369 - 4387 (2020)
Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 5.
Zeitschriftenartikel
48 (3), S. 1056 - 1067 (2020)
Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 6.
Zeitschriftenartikel
10 (1), 97 (2020)
Cotranslational folding of proteins on the ribosome. Biomolecules 7.
Zeitschriftenartikel
5 (12), eaax8030 (2019)
Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 8.
Zeitschriftenartikel
401 (1), S. 131 - 142 (2019)
Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 9.
Zeitschriftenartikel
10, 4598 (2019)
Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10.
Zeitschriftenartikel
593 (13), S. 1468 - 1482 (2019)
Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 11.
Zeitschriftenartikel
593 (13), S. 1483 - 1493 (2019)
The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 12.
Zeitschriftenartikel
5 (6), eaaw9049 (2019)
EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 13.
Zeitschriftenartikel
47 (10), S. 5210 - 5222 (2019)
Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 14.
Zeitschriftenartikel
47 (9), S. 4798 - 4813 (2019)
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3. Nucleic Acids Research 15.
Zeitschriftenartikel
47 (6), S. 2932 - 2945 (2019)
Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 16.
Zeitschriftenartikel
141 (26), S. 10236 - 10246 (2019)
Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors. Journal of the American Chemical Society 17.
Zeitschriftenartikel
46 (22), e130 (2018)
Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis. Nucleic Acids Research 18.
Zeitschriftenartikel
46 (16), S. 8079 - 8089 (2018)
Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting. Nucleic Acids Research 19.
Zeitschriftenartikel
32 (17-18), S. 1226 - 1241 (2018)
Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes and Development 20.
Zeitschriftenartikel
9, 3053 (2018)
Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 21.
Zeitschriftenartikel
8 (1), 9922 (2018)
Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 22.
Zeitschriftenartikel
57 (25), S. 3460 - 3464 (2018)
Co-translational folding trajectory of the HemK helical domain. Biochemistry 23.
Zeitschriftenartikel
7, e34252 (2018)
Dynamics of ribosomes and release factors during translation termination in E-coli. eLife 24.
Zeitschriftenartikel
115 (17), S. 4411 - 4416 (2018)
Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA. Proceedings of the National Academy of Sciences of the United States of America 25.
Zeitschriftenartikel
10 (9), a032664 (2018)
Translation in prokaryotes. Cold Spring Harbor Perspectives in Biology 26.
Zeitschriftenartikel
115 (12), S. 3018 - 3023 (2018)
Deciphering the reading of the genetic code by near-cognate tRNA. Proceedings of the National Academy of Sciences of the United States of America 27.
Zeitschriftenartikel
45 (20), S. 11858 - 11866 (2017)
Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 28.
Zeitschriftenartikel
68 (3), S. 515 - 527 (2017)
Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 29.
Zeitschriftenartikel
20 (13), S. 3113 - 3122 (2017)
Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 30.
Zeitschriftenartikel
7, 10536 (2017)
Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 31.
Zeitschriftenartikel
24 (9), S. 752 - 757 (2017)
An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 32.
Zeitschriftenartikel
3 (6), e1700147 (2017)
Ribosome rearrangements at the onset of translational bypassing. Science Advances 33.
Zeitschriftenartikel
66 (4), S. 558 - 567 (2017)
Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 34.
Zeitschriftenartikel
8, 15562 (2017)
Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 35.
Zeitschriftenartikel
139 (16), S. 5857 - 5864 (2017)
Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 36.
Zeitschriftenartikel
372 (1716), 20160182 (2017)
Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 37.
Zeitschriftenartikel
42, S. 83 - 89 (2017)
Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 38.
Zeitschriftenartikel
540 (7631), S. 80 - 85 (2016)
The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 39.
Zeitschriftenartikel
35 (19), S. 2104 - 2119 (2016)
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 40.
Zeitschriftenartikel
102 (1), S. 152 - 167 (2016)
The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 41.
Zeitschriftenartikel
16 (8), S. 2187 - 2196 (2016)
Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 42.
Zeitschriftenartikel
55 (33), S. 9544 - 9547 (2016)
Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 43.
Zeitschriftenartikel
105 (8), S. 463 - 475 (2016)
Translational GTPases. Biopolymers 44.
Zeitschriftenartikel
25 (8), S. 1390 - 1406 (2016)
The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 45.
Zeitschriftenartikel
7, 11657 (2016)
Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 46.
Zeitschriftenartikel
428 (10, P. B), S. 2165 - 2185 (2016)
Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 47.
Zeitschriftenartikel
113 (16), S. E2286 - E2295 (2016)
Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 48.
Zeitschriftenartikel
23 (4), S. 342 - 348 (2016)
Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 49.
Zeitschriftenartikel
61 (3), S. 341 - 351 (2016)
Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 50.
Zeitschriftenartikel
4 (1), e1143076 (2016)
tRNA wobble modifications and protein homeostasis. Translation 51.
Zeitschriftenartikel
13 (12), S. 1197 - 1203 (2016)
Translocation as continuous movement through the ribosome. RNA Biology 52.
Zeitschriftenartikel
43 (22), S. 10700 - 10712 (2015)
Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 53.
Zeitschriftenartikel
119 (49), S. 11820 - 11836 (2015)
Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 54.
Zeitschriftenartikel
21 (12), S. 2047 - 2052 (2015)
Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 55.
Zeitschriftenartikel
250 (6264), S. 1104 - 1107 (2015)
Cotranslational protein folding on the ribosome monitored in real time. Science 56.
Zeitschriftenartikel
137 (40), S. 12997 - 13006 (2015)
Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 57.
Zeitschriftenartikel
211 (1), S. 91 - 104 (2015)
Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 58.
Zeitschriftenartikel
43 (13), S. 6426 - 6438 (2015)
Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 59.
Zeitschriftenartikel
6, 7442 (2015)
Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 60.
Zeitschriftenartikel
112 (19), S. 6033 - 6037 (2015)
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 61.
Zeitschriftenartikel
40 (5), S. 265 - 274 (2015)
Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 62.
Zeitschriftenartikel
520 (7548), S. 567 - 570 (2015)
Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 63.
Zeitschriftenartikel
15 (5-6), S. 862 - 879 (2015)
Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 64.
Zeitschriftenartikel
56 (4), S. 531 - 540 (2014)
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 65.
Zeitschriftenartikel
10 (10), e1003909 (2014)
Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 66.
Zeitschriftenartikel
5, 5263 (2014)
Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 67.
Zeitschriftenartikel
111 (40), S. 14418 - 14423 (2014)
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 68.
Zeitschriftenartikel
36 (10), S. 908 - 918 (2014)
Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 69.
Zeitschriftenartikel
513 (7519), S. 517 - 522 (2014)
Structural basis for the inhibition of the eukaryotic ribosome. Nature 70.
Zeitschriftenartikel
5, 4459 (2014)
High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 71.
Zeitschriftenartikel
157 (7), S. 1619 - 1631 (2014)
Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 72.
Zeitschriftenartikel
5, 4180 (2014)
Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 73.
Zeitschriftenartikel
33 (9), S. 1073 - 1085 (2014)
GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 74.
Zeitschriftenartikel
42 (3), S. 1812 - 1820 (2014)
Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 75.
Zeitschriftenartikel
20 (12), S. 1390 - 1396 (2013)
Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 76.
Zeitschriftenartikel
99 (11), S. 837 - 845 (2013)
Elongation factor P: Function and effects on bacterial fitness. Biopolymers 77.
Zeitschriftenartikel
135 (45), S. 17031 - 17038 (2013)
A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 78.
Zeitschriftenartikel
23 (4), S. 595 - 602 (2013)
The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 79.
Zeitschriftenartikel
110 (30), S. 12289 - 12294 (2013)
tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 80.
Zeitschriftenartikel
340 (6140), S. 1534 - 1535 (2013)
Translocation in action. Science 81.
Zeitschriftenartikel
1 (1), e24315 (2013)
Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 82.
Zeitschriftenartikel
4, 1387 (2013)
Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nature Communications 83.
Zeitschriftenartikel
339 (6115), S. 85 - 88 (2013)
EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science 84.
Zeitschriftenartikel
19 (12), S. 1332 - 1337 (2012)
Dynamic switch of the signal recognition particle from scanning to targeting. Nature Structural and Molecular Biology 85.
Zeitschriftenartikel
18 (12), S. 2306 - 2319 (2012)
Novel insights into the architecture and protein interaction network of yeast eIF3. RNA 86.
Zeitschriftenartikel
287 (33), S. 27906 - 27912 (2012)
Thermodynamics of the GTP-GDP operated conformational switch of selenocysteine-specific translation factor SelB. Journal of Biological Chemistry 87.
Zeitschriftenartikel
47 (4), S. 334 - 348 (2012)
Kinetic control of translation initiation in bacteria. Critical Reviews in Biochemistry and Molecular Biology 88.
Zeitschriftenartikel
40 (16), S. 7885 - 7895 (2012)
Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation. Nucleic Acids Research 89.
Zeitschriftenartikel
109 (6), S. 2102 - 2107 (2012)
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid. Proceedings of the National Academy of Sciences of the United States of America 90.
Zeitschriftenartikel
19 (6), S. 609 - 615 (2012)
Real-time assembly landscape of bacterial 30S translation initiation complex. Nature Structural and Molecular Biology 91.
Zeitschriftenartikel
6 (12), e29525 (2011)
Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for legionella pneumophila effector glucosyltransferases. PLoS One 92.
Zeitschriftenartikel
366 (1580), S. 2979 - 2986 (2011)
Evolutionary optimization of speed and accuracy of decoding on the ribosome. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 93.
Zeitschriftenartikel
585 (19), S. 3073 - 3078 (2011)
The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome. FEBS Letters 94.
Zeitschriftenartikel
476, S. 351 - 354 (2011)
Different substrate-dependent transition states in the active site of the ribosome. Nature 95.
Zeitschriftenartikel
9 (7), e1001095 (2011)
The cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biology 96.
Zeitschriftenartikel
286 (10), S. 8158 - 8164 (2011)
Distortion of tRNA upon near-cognate codon recognition on the ribosome. Journal of Biological Chemistry 97.
Zeitschriftenartikel
39, S. 658 - 662 (2011)
The ribosome as a molecular machine: The mechanism of tRNA–mRNA movement in translocation. Biochemical Society Transactions 98.
Zeitschriftenartikel
17 (4), S. 389 - 392 (2011)
Genauigkeit und Geschwindigkeit der Proteinsynthese. Biospektrum 99.
Zeitschriftenartikel
29 (21), S. 3701 - 3709 (2010)
Optimization of speed and accuracy of decoding in translation. The EMBO Journal