Publikationen

Zeitschriftenartikel (350)

1.
Zeitschriftenartikel
Ukmar-Godec, T.; Fang, P.; Ibáñez de Opakua, A.; Henneberg, F.; Godec, A.; Pan, K. T.; Cima-Omori, M.-S.; Chari, A.; Mandelkow, E.; Urlaub, H. et al.; Zweckstetter, M.: Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 6 (30), eaba3916 (2020)
2.
Zeitschriftenartikel
Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E.; Hofele, R. V.; Urlaub, H.; Kastner, B.; Lührmann, R. et al.; Stark, H.: Molecular architecture of the human 17S U2 snRNP. Nature 583 (7815), S. 310 - 313 (2020)
3.
Zeitschriftenartikel
Königsmann, T.; Parfentev, I.; Urlaub, H.; Riedel, D.; Schuh, R.: The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila. Developmental Biology 463 (1), S. 53 - 62 (2020)
4.
Zeitschriftenartikel
Linden, A.; Deckers, M.; Parfentev, I.; Pflanz, R.; Homberg, B.; Neumann, P.; Ficner, R.; Rehling, P.; Urlaub, H.: A Cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria. Molecular and Cellular Proteomics 19 (7), S. 1161 - 1178 (2020)
5.
Zeitschriftenartikel
Vos, S. M.; Farnung, L.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 27 (7), S. 668 - 677 (2020)
6.
Zeitschriftenartikel
Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)
7.
Zeitschriftenartikel
Specht, G.; Roetschke, H. P.; Mansurkhodzhaev, A.; Henklein, P.; Textoris-Taube, K.; Urlaub, H.; Mishto, M.; Liepe, J.: Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 7, 146 (2020)
8.
Zeitschriftenartikel
Singh, K.; Graf, B.; Linden, A.; Sautner, V.; Urlaub, H.; Tittmann, K.; Stark, H.; Chari, A.: Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 180 (6), S. 1130 - 1143.e20 (2020)
9.
Zeitschriftenartikel
Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), S. 448 - 451 (2020)
10.
Zeitschriftenartikel
Müller, M.; James, C.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Probing the environment of emerin by Enhanced ascorbate peroxidase 2 (APEX2)-mediated proximity labeling. Cells 9 (3), 605 (2020)
11.
Zeitschriftenartikel
Volland, C.; Schott, P.; Didié, M.; Männer, J.; Unsöld, B.; Toischer, K.; Schmidt, C.; Urlaub, H.; Nickels, K.; Knöll, R. et al.; Schmidt, A.; Guan, K.; Hasenfuß, G.; Seidler, T.: Control of p21Cip by BRAP is critical for cardiomyocyte cell cycle progression and survival. Cardiovascular Research 116 (3), S. 592 - 604 (2020)
12.
Zeitschriftenartikel
Koziolek, M.; Mueller, G. A.; Dihazi, G. H.; Jung, K.; Altubar, C.; Wallbach, M.; Markovic, I.; Raddatz, D.; Jahn, O.; Karaköse, H. et al.; Lenz, C.; Urlaub, H.; Dihazi, A.; El Meziane, A.; Dihazi, H.: Urine E-cadherin: A Marker for early detection of kidney injury in diabetic patients. Journal of Clinical Medicine 9 (3), 639 (2020)
13.
Zeitschriftenartikel
Hamann, F.; Schmitt, A.; Favretto, F.; Hofele, R.; Neumann, P.; Xiang, S. Q.; Urlaub, H.; Zweckstetter, M.; Ficner, R.: Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences of the United States of America 117 (6), S. 2948 - 2956 (2020)
14.
Zeitschriftenartikel
Yatsenko, A. S.; Kucherenko, M. M.; Xie, Y.; Aweida, D.; Urlaub, H.; Scheibe, R. J.; Cohen, S.; Shcherbata, H. R.: Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC Medicine 18 (1), 8 (2020)
15.
Zeitschriftenartikel
Völkel, S.; Hein, S.; Benker, N.; Pfeifer, F.; Lenz, C.; Losensky, G.: How to cope with heavy metal ions: Cellular and proteome-level stress response to divalent copper and nickel in Halobacterium salinarum R1 planktonic and biofilm cells. Frontiers in Microbiology 10, 3056 (2020)
16.
Zeitschriftenartikel
Godavarthy, P. S.; Kumar, R.; Herkt, S. C.; Pereira, R. S.; Hayduk, N.; Weissenberger, E. S.; Aggoune, D.; Manavski, Y.; Lucas, T.; Pan, K. T. et al.; Voutsinas, J. M.; Wu, Q.; Müller, M. C.; Saussele, S.; Oellerich, T.; Oehler, V. G.; Lausen, J.; Krause, D. S.: The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. Haematologica 105 (1), S. 136 - 147 (2020)
17.
Zeitschriftenartikel
Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, S. 717 - 720 (2020)
18.
Zeitschriftenartikel
Keihani, S.; Klüver, V.; Mandad, S.; Bansal, V.; Rahman, R.; Fritsch, E.; Gomes, L. C.; Gärtner, A.; Kügler, S.; Urlaub, H. et al.; Wren, J. D.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43. Science Advances 5 (12), eaay2670 (2019)
19.
Zeitschriftenartikel
Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), S. 1537 - 1550 (2019)
20.
Zeitschriftenartikel
Gowravaram, M.; Schwarz, J.; Khilji, S. K.; Urlaub, H.; Chakrabarti, S.: Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. Nature Communications 10 (1), 5054 (2019)
21.
Zeitschriftenartikel
Alevra, M.; Mandad, S.; Ischebeck, T.; Urlaub, H.; Rizzoli, S. O.; Fornasiero, E. F.: A mass spectrometry workflow for measuring protein turnover rates in vivo. Nature Protocols 14 (12), S. 3333 - 3365 (2019)
22.
Zeitschriftenartikel
Ayoubi, L. E.; Dumay-Odelot, H.; Chernev, A.; Boissier, F.; Minvielle-Sébastia, L.; Urlaub, H.; Fribourg, S.; Teichmann, M.: The hRPC62 subunit of human RNA polymerase III displays helicase activity. Nucleic Acids Research 47 (19), S. 10313 - 10326 (2019)
23.
Zeitschriftenartikel
James, C.; Müller, M.; Goldberg, M. W.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. The Journal of Biological Chemistry 294 (44), S. 16241 - 16254 (2019)
24.
Zeitschriftenartikel
Blazquez, R.; Rietkötter, E.; Wenske, B.; Wlochowitz, D.; Sparrer, D.; Vollmer, E.; Müller, G.; Seegerer, J.; Sun, X.; Dettmer, K. et al.; Barrantes-Freer, A.; Stange, L.; Utpatel, K.; Bleckmann, A.; Treiber, H.; Bohnenberger, H.; Lenz, C.; Schulz, M.; Reimelt, C.; Hackl, C.; Grade, M.; Büyüktas, D.; Siam, L.; Balkenhol, M.; Stadelmann, C.; Kube, D.; Krahn, M. P.; Proescholdt, M. A.; Riemenschneider, M. J.; Evert, M.; Oefner, P. J.; Klein, C. A.; Hanisch, U. K.; Binder, C.; Pukrop, T.: LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. International Journal of Cancer, (in press) (2019)
25.
Zeitschriftenartikel
Erdmann, J.; Thöming, J. G.; Pohl, S.; Pich, A.; Lenz, C.; Häussler, S.: The core proteome of biofilm-grown clinical pseudomonas aeruginosa isolates. Cells 8 (10), 1129 (2019)
26.
Zeitschriftenartikel
Jevtic, Z.; Stoll, B.; Pfeiffer, F.; Sharma, K.; Urlaub, H.; Marchfelder, A.; Lenz, C.: The response of Haloferax volcanii to salt and temperature stress: A proteome study by label-free mass spectrometry. Proteomics 19 (20), 1840091 (2019)
27.
Zeitschriftenartikel
Bremmer, F.; Bohnenberger, H.; Küffer, S.; Oellerich, T.; Serve, H.; Urlaub, H.; Strauss, A.; Maatoug, Y.; Behnes, C. L.; Oing, C. et al.; Radzun, H. J.; Ströbel, P.; Balabanov, S.; Honecker, F.: Proteomic comparison of malignant human germ cell tumor cell lines. Disease Markers 2019, 8298524 (2019)
28.
Zeitschriftenartikel
Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)
29.
Zeitschriftenartikel
Alsina, K. M.; Hulsurkar, M.; Brandenburg, S.; Kownatzki-Danger, D.; Lenz, C.; Urlaub, H.; Abu-Taha, I.; Kamler, M.; Chiang, D. Y.; Lahiri, S. K. et al.; Reynolds, J. O.; Quick, A. P.; Scott, L.; Word, T. A.; Gelves, M. D.; Heck, A. J. R.; Li, N.; Dobrev, D.; Lehnart, S. E.; Wehrens, X. H. T.: Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 140 (8), S. 681 - 693 (2019)
30.
Zeitschriftenartikel
Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Yu, L.; Roumeliotis, T. I.; Diebold, M.; Dybkov, O.; Sotriffer, C.; Urlaub, H.; Choudhary, J. S. et al.; Mansfeld, J.; Lorenz, S.: Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 27 (8), S. 1195 - 1210 (2019)
31.
Zeitschriftenartikel
Callegari, S.; Müller, T.; Schulz, C.; Lenz, C.; Jans, D. C.; Wissel, M.; Opazo, F.; Rizzoli, S. O.; Jakobs, S.; Urlaub, H. et al.; Rehling, P.; Deckers, M.: A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 431 (15), S. 2835 - 2851 (2019)
32.
Zeitschriftenartikel
Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)
33.
Zeitschriftenartikel
Coy-Vergara, J.; Rivera-Monroy, J.; Urlaub, H.; Lenz, C.; Schwappach, B.: A trap mutant reveals the physiological client spectrum of TRC40. Journal of Cerll Science, (in press) (2019)
34.
Zeitschriftenartikel
Chachami, G.; Stankovic-Valentin, N.; Karagiota, A.; Basagianni, A.; Pleßmann, U.; Urlaub, H.; Melchior, F.; Simos, G.: Hypoxia-induced changes in SUMO conjugation affect transcriptional regulation under low oxygen. Molecular and Cellular Proteomics 18 (6), S. 1197 - 1209 (2019)
35.
Zeitschriftenartikel
Garofalo, R.; Wohlgemuth, I.; Pearson, M.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 47 (6), S. 2932 - 2945 (2019)
36.
Zeitschriftenartikel
Papathanasiou, P.; Erdmann, S.; Leon-Sobrino, C.; Sharma, K.; Urlaub, H.; Garrett, R. A.; Peng, X.: Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 16 (4), S. 557 - 565 (2019)
37.
Zeitschriftenartikel
Schroeder, M. P.; Bastian, L.; Eckert, C.; Gökbuget, N.; James, A. R.; Ortiz Tanchez, J.; Schlee, C.; Isaakidis, K.; Häupl, B.; Baum, K. et al.; Lozano, O. A. M.; Kouidri, K.; Pan, K. T.; Urlaub, H.; Schwartz, S.; Burmeister, T.; von Stackelberg, A.; Hoelzer, D.; Pfeiffer, H.; Rieger, M. A.; Göllner, S.; Oellerich, T.; Horstman, M.; Schrappe, M.; Wolf, J.; Kirschner-Schwabe, R.; Brüggemann, M.; Müller-Tidow, C.; Serve, H.; Neumann, M.; Baldus, C. D.: Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Scientific Reports 9 (1), 4188 (2019)
38.
Zeitschriftenartikel
Michels, B. E.; Mosa, M. H.; Grebbin, B. M.; Yepes, D.; Darvishi, T.; Hausmann, J.; Urlaub, H.; Zeuzem, S.; Kvasnicka, H. M.; Oellerich, T. et al.; Farin, H. F.: Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. Journal of Experimental Medicine 216 (3), 704 (2019)
39.
Zeitschriftenartikel
Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 218 (2), 598 (2019)
40.
Zeitschriftenartikel
Maier, L. K.; Stachler, A. E.; Brendel, J.; Stoll, B.; Fischer, S.; Haas, K.; Schwarz, T.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H. et al.; Backofen, R.; Gophna, U.; Marchfelder, A.: The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 16 (4), S. 469 - 480 (2019)
41.
Zeitschriftenartikel
Masanta, W. O.; Zautner, A. E.; Lugert, R.; Bohne, W.; Gross, U.; Leha, A.; Dakna, M.; Lenz, C.: Proteome profiling by label‐free mass spectrometry reveals differentiated response of Campylobacter jejuni 81–176 to sublethal concentrations of bile acids. Proteomics 13 (3), 1800083 (2019)
42.
Zeitschriftenartikel
Mishto, M.; Mansurkhodzhaev, A.; Ying, G.; Bitra, A.; Cordfunke, R. A.; Henze, S.; Paul, D.; Sidney, J.; Urlaub, H.; Neefjes, J. et al.; Sette, A.; Zajonc, D. M.; Liepe, J.: An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 10, 2572 (2019)
43.
Zeitschriftenartikel
Özcan, A.; Pausch, P.; Linden, A.; Wulf, A.; Schühle, K.; Heider, J.; Urlaub, H.; Heimerl, T.; Bange, G.; Randau, L.: Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiology 4 (1), S. 89 - 96 (2019)
44.
Zeitschriftenartikel
Ramani, A.; Mariappan, A.; Gottardo, M.; Mandad, S.; Urlaub, H.; Avidor-Reiss, T.; Riparbelli, M.; Giuliano, C.; Debec, A.; Feederle, R. et al.; Gopalakrishnan, J.: Plk1/Polo phosphorylates Sas-4 at the onset of mitosis for an efficient recruitment of pericentriolar material to centrosomes. Cell Reports 25 (13), S. 3618 - 3630 (2018)
45.
Zeitschriftenartikel
Brüning, L.; Hackert, P.; Martin, R.; Gallesio, J. D.; Aquino, G. R. R.; Urlaub, H.; Sloan, K. E.; Bohnsack, M. T.: RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes. Nature Communications 9, 5383 (2018)
46.
Zeitschriftenartikel
Braun, J.; Fischer, S.; Xu, Z. Z.; Dalia, S.; Ghoneim, D. H.; Gimbel, A. T.; Plessmann, U.; Urlaub, H.; Mathews, D. H.; Weigand, J. E.: Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Research 46 (22), S. 12109 - 12125 (2018)
47.
Zeitschriftenartikel
Mariappan, A.; Soni, K.; Schorpp, K.; Zhao, F.; Minakar, A.; Zheng, X.; Mandad, S.; Macheleidt, I.; Ramani, A.; Kubelka, T. et al.; Dawidowski, M.; Golfmann, K.; Wason, A.; Yang, C.; Simons, J.; Schmalz, H. G.; Hyman, A. A.; Aneja, R.; Ullrich, R.; Urlaub, H.; Odenthal, M.; Büttner, R.; Li, H.; Sattler, M.; Hadian, K.; Gopalakrishnan, J.: Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. The EMBO Journal, In press (e99876) (2018)
48.
Zeitschriftenartikel
Mandad, S.; Rahman, R. U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T. et al.; Kirli, K.; Benito, E.; Fischer, A.; Yousefi, R. Y.; Dennerlein, S.; Rehling, P.; Feussner, I.; Urlaub, H.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 8, 16913 (2018)
49.
Zeitschriftenartikel
Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9, 4532 (2018)
50.
Zeitschriftenartikel
Buskin, A.; Zhu, L.; Chichagova, V.; Basu, B.; Mozafarri Jovin, S.; Dolan, D.; Droop, A.; Collin, J.; Bronstein, R.; Mehrotra, S. et al.; Farkas, M.; Hilgen, G.; White, K.; Pan, K. T.; Treumann, A.; Hallam, D.; Bialas, K.; Chung, G.; Mellough, C.; Ding, Y.; Krasnogor, N.; Przyborski, S.; Zwolinski, S.; Al-Aama, J.; Alharthi, S.; Xu, Y.; Wheway, G.; Szymanska, K.; McKibbin, M.; Inglehearn, C. F.; Elliott, D. J.; Lindsay, S.; Ali, R. R.; Steel, D. H.; Armstrong, L.; Sernagor, E.; Urlaub, H.; Pierce, E.; Lührmann, R.; Grellscheid, S. N.; Johnson, C. A.; Lako, M.: Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 9, 4234 (2018)
51.
Zeitschriftenartikel
Fornasiero, E. F.; Mandad, S.; Wildhagen, H.; Alevra, M.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T.; Sakib, M. S. et al.; Fard, M. K.; Kirli, K.; Centeno, T. P.; Vidal, R. O.; Rahman, R. U.; Benito, E.; Fischer, A.; Dennerlein, S.; Rehling, P.; Feussner, I.; Bonn, S.; Simons, M.; Urlaub, H.; Rizzoli, S. O.: Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nature Communications 9, 4230 (2018)
52.
Zeitschriftenartikel
Lavdovskaia, E.; Kolander, E.; Steube, E.; Mai, M. M.; Urlaub, H.; Richter-Dennerlein, R.: The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Research 46 (16), S. 8471 - 8482 (2018)
53.
Zeitschriftenartikel
Blaschke, M.; Koepp, R.; Lenz, C.; Kruppa, J.; Jung, K.; Siggelkow, H.: Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. Journal of Clinical and Translational Endocrinology 13, S. 26 - 38 (2018)
54.
Zeitschriftenartikel
Bohnenberger, H.; Kaderali, L.; Ströbel, P.; Yepes, D.; Pleßmann, U.; Dharia, N. Y.; Yao, S.; Heydt, C.; Merkelbach‐Bruse, S.; Emmert, A. et al.; Hoffmann, J.; Bodemeyer, J.; Reuter‐Jessen, K.; Lois, A. M.; Dröge, L. H.; Baumeister, P.; Walz, C.; Biggemann, L.; Walter, R.; Häupl, B.; Comoglio, F.; Pan, K. T.; Scheich, S.; Lenz, C.; Küffer, S.; Bremmer, F.; Kitz, J.; Sitte, M.; Beißbarth, T.; Hinterthaner, M.; Sebastian, M.; Lotz, J.; Schildhaus, H. U.; Wolff, H.; Danner, B. C.; Brandts, C.; Büttner, R.; Canis, M.; Stegmaier, K.; Serve, H.; Urlaub, H.; Oellerich, T.: Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. EMBO Molecular Medicine 10 (9), e8428 (2018)
55.
Zeitschriftenartikel
Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), S. 607 - 612 (2018)
56.
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Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), S. 601 - 606 (2018)
57.
Zeitschriftenartikel
Mühlhausen, S.; Schmitt, H. D.; Pan, K. T.; Plessmann, U.; Urlaub, H.; Hurst, L. D.; Kollmar, M.: Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica. Current Biology 28 (13), S. 2046 - 2057 (2018)
58.
Zeitschriftenartikel
Aksu, M.; Pleiner, T.; Karaca, S.; Kappert, C.; Dehne, H. J.; Seibel, K.; Urlaub, H.; Bohnsack, M. T.; Görlich, D.: Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 217 (7), S. 2329 - 2340 (2018)
59.
Zeitschriftenartikel
Cyganek, L.; Tiburcy, M.; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H.; Lenz, C.; Henze, S.; Stauske, M.; Salinas, G.; Zimmermann, W. H. et al.; Hasenfuss, G.; Guan, K.: Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight 3 (12), e99941 (2018)
60.
Zeitschriftenartikel
Johannsson, S.; Neumann, P.; Wulf, A.; Welp, L. M.; Gerber, H. D.; Krull, M.; Diederichsen, U.; Urlaub, H.; Ficner, R.: Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Scientific Reports 8, 8880 (2018)
61.
Zeitschriftenartikel
Dihazi, H.; Asif, A. R.; Beißbarth, T.; Bohrer, R.; Feussner, K.; Feussner, I.; Jahn, O.; Lenz, C.; Majcherczyk, A.; Schmidt, B. et al.; Schmitt, K.; Urlaub, H.; Valerius, O.: Integrative omics - from data to biology. Expert Review of Proteomics 15 (6), S. 463 - 466 (2018)
62.
Zeitschriftenartikel
Zaman, U.; Urlaub, H.; Abbasi, A.: Protein profiling of non-model plant Cuminum cyminum by gel-based proteomic approach. Phytochemical Analysis 29 (3), S. 242 - 249 (2018)
63.
Zeitschriftenartikel
Dickmanns, A.; Zschiedrich, C. P.; Arens, J.; Parfentev, I.; Gundlach, J.; Hofele, R.; Neumann, P.; Urlaub, H.; Görke, B.; Ficner, R. et al.; Stulke, J.: Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis. The Journal of Biological Chemistry 293 (16), S. 5781 - 5792 (2018)
64.
Zeitschriftenartikel
Batschkus, S.; Cingoez, G.; Urlaub, H.; Miosge, N.; Kirschneck, C.; Meyer-Marcotty, P.; Lenz, C.: A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients. Clinical Oral Investigations 22 (3), S. 1375 - 1384 (2018)
65.
Zeitschriftenartikel
Rocha de Moura, T.; Mozaffari-Jovin, S.; Szabo, C. Z. K.; Schmitzova, J.; Dybkov, O.; Cretu, C.; Kachala, M.; Svergun, D.; Urlaub, H.; Lührmann, R. et al.; Pena, V.: Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 69 (6), S. 979 - 992 (2018)
66.
Zeitschriftenartikel
Behler, J.; Sharma, K.; Reimann, V.; Wilde, A.; Urlaub, H.; Hess, W. R.: The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiology 3 (3), S. 367 - 377 (2018)
67.
Zeitschriftenartikel
Buddeweg, A.; Sharma, K.; Urlaub, H.; Schmitz, R. A.: sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. Molecular Microbiology 107 (5), S. 595 - 609 (2018)
68.
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Sonnleitner, E.; Wulf, A.; Campagne, S.; Pei, X. Y.; Wolfinger, M. T.; Forlani, G.; Prindl, K.; Abdou, L.; Resch, A.; Allain, F. H. et al.; Luisi, B. F.; Urlaub, H.; Bläsi, U.: Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa. Nucleic Acids Research 46 (3), S. 1470 - 1485 (2018)
69.
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Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 172 (3), S. 454 - 464, e1-e5 (2018)
70.
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Fard, M. K.; van der Meer, F.; Sánchez, P.; Cantuti-Castelvetri, L.; Mandad, S.; Jäkel, S.; Fornasiero, E. F.; Schmitt, S.; Ehrlich, M.; Starost, L. et al.; Kuhlmann, T.; Sergiou, C.; Schultz, V.; Wrzos, C.; Brück, W.; Urlaub, H.; Dimou, L.; Stadelmann, C.; Simons, M.: BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science Translational Medicine 9 (419), eaam7816 (2017)
71.
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Bao, P.; Will, C. L.; Urlaub, H.; Boon, K. L.; Lührmann, R.: The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development 31 (23-24), S. 2416 - 2429 (2017)
72.
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Ahdash, Z.; Lau, A. M.; Byrne, R. T.; Lammens, K.; Stützer, A.; Urlaub, H.; Booth, P. J.; Reading, E.; Hopfner, K. P.; Politis, A.: Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex. Nucleic Acids Research 45 (20), S. 12025 - 12038 (2017)
73.
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Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), S. 1082 - 1093 (2017)
74.
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Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), S. 204 - 209 (2017)
75.
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Warda, A. S.; Kretschmer, J.; Hackert, P.; Lenz, C.; Urlaub, H.; Höbartner, C.; Sloan, K. E.; Bohnsack, M. T.: Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. EMBO Reports 18 (11), S. 2004 - 2014 (2017)
76.
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Scacioc, A.; Schmidt, C.; Hofmann, T.; Urlaub, H.; Kühnel, K.; Perez-Lara, A.: Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding. Scientific Reports 7, 14008 (2017)
77.
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Schmidt , C.; Urlaub, H.: Combining cryo-electron microscopy (cryo-EM) and cross-linking mass spectrometry (CX-MS) for structural elucidation of large protein assemblies. Current Opinion in Structural Biology 46, S. 157 - 168 (2017)
78.
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Märtens, B.; Sharma, K.; Urlaub, H.; Bläsi, U.: The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus. Nucleic Acids Research 45 (15), S. 8957 - 8967 (2017)
79.
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Wottawa, M.; Naas, S.; Böttger, J.; van Belle, G. J.; Möbius, W.; Revelo, N. H.; Heidenreich, D.; von Ahlen, M.; Zieseniss, A.; Kröhnert, K. et al.; Lutz, S.; Lenz, C.; Urlaub, H.; Rizzoli, S. O.; Katschinski, D. M.: Hypoxia-stimulated membrane trafficking requires T-plastin. Acta Physiologica 221 (1), S. 59 - 73 (2017)
80.
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Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 170 (4), S. 701 - 713, e1 - e4 (2017)
81.
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Henning, L. M.; Santos, K. F.; Sticht, J.; Jehle, S.; Lee, C. T.; Wittwer, M.; Urlaub, H.; Stelzl, U.; Wahl, M. C.; Freund, C.: A new role for FBP21 as regulator of Brr2 helicase activity. Nucleic Acids Research 45 (13), S. 7922 - 7937 (2017)
82.
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Batschkus, S.; Atanassov, I.; Lenz, C.; Meyer-Marcotty, P.; Cingöz, G.; Kirschneck, C.; Urlaub, H.; Miosge, N.: Mapping the secretome of human chondrogenic progenitor cells with mass spectrometry. Annals of Anatomy 212, S. 4 - 10 (2017)
83.
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Said, N.; Krupp, F.; Anedchenko, E.; Santos, K. F.; Dybkov, O.; Huang, Y. H.; Lee, C. T.; Loll, B.; Behrmann, E.; Bürger, J. et al.; Mielke, T.; Loerke, J.; Urlaub, H.; Spahn, C. M. T.; Weber, G.; Wahl, M. C.: Structural basis for λN-dependent processive transcription antitermination. Nature Microbiology 2 (7), 17062 (2017)
84.
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Jakhanwal, S.; Lee, C. T.; Urlaub, H.; Jahn, R.: An activated Q-SNARE/SM protein complex as a possible intermediate in SNARE assembly. EMBO Journal 36 (12), S. 1788 - 1802 (2017)
85.
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Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8, 15741 (2017)
86.
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Treiber, T.; Treiber, N.; Plessmann, U.; Harlander, S.; Daiss, J. L.; Eichner, N.; Lehmann, G.; Schall, K.; Urlaub, H.; Meister, G.: A compendium of RNA-binding proteins that regulate microRNA biogenesis. Molecular Cell 66 (2), S. 270 - 284 (2017)
87.
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Pan, K. T.; Chen, C. C.; Urlaub, H.; Khoo, K. H.: Adapting data-independent acquisition for mass spectrometry-based protein site-specific N-glycosylation analysis. Analytical Chemistry 89 (8), S. 4532 - 4539 (2017)
88.
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Mohr, S.; Doebele, C.; Comoglio, F.; Berg, T.; Beck, J.; Bohnenberger, H.; Alexe, G.; Corso, J.; Ströbel, P.; Wachter, A. et al.; Beissbarth, T.; Schnutgen, F.; Cremer, A.; Haetscher, N.; Göllner, S.; Rouhi, A.; Palmqvist, L.; Rieger, M. A.; Schroeder, T.; Bönig, H.; Müller-Tidow, C.; Kuchenbauer, F.; Schütz, E.; Green, A. R.; Urlaub, H.; Stegmaier, K.; Humphries, R. K.; Serve, H.; Oellerich, T.: Hoxa9 and Meis1 cooperatively induce addiction to Syk signaling by suppressing miR-146a in acute myeloid leukemia. Cancer Cell 31 (4), S. 549 - 562 (2017)
89.
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Losensky, G.; Jung, K.; Urlaub, H.; Pfeifer, F.; Fröls, S.; Lenz, C.: Shedding light on biofilm formation of Halobacterium salinarum R1 by SWATH-LC/MS/MS analysis of planktonic and sessile cells. Proteomics 17 (7), 1600111 (2017)
90.
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Sidarovich, A.; Will, C. L.; Anokhina, M. M.; Ceballos, J.; Sievers, S.; Agafonov, D. E.; Samatov, T.; Bao, P.; Kastner, B.; Urlaub, H. et al.; Waldmann, H.; Lührmann, R.: Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. eLife 6, e23533 (2017)
91.
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Bertram, K.; Agafonov, D. E.; Liu, W.; Dybkov, O.; Will, C. L.; Hartmuth, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 542 (7641), S. 318 - 323 (2017)
92.
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Walter, R.; Pan, K. T.; Doebele, C.; Comoglio, F.; Tomska, K.; Bohnenberger, H.; Young, R. M.; Jacobs, L.; Keller, U.; Bönig, H. et al.; Engelke, M.; Rosenwald, A.; Urlaub, H.; Staudt, L. M.; Serve, H.; Zenz, T.; Oellerich, T.: HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B cell receptor signaling. Blood 129 (5), S. 598 - 608 (2017)
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Göllner, S.; Oellerich, T.; Agrawal-Singh, S.; Schenk, T.; Klein, H. U.; Rohde, C.; Pabst, C.; Sauer, T.; Lerdrup, M.; Tavor, S. et al.; Stölzel, F.; Herold, S.; Ehninger, G.; Köhler, G.; Pan, K. T.; Urlaub, H.; Serve, H.; Dugas, M.; Spiekermann, K.; Vick, B.; Jeremias, I.; Berdel, W. E.; Hansen, K.; Zelent, A.; Wickenhauser, C.; Müller, L. P.; Thiede, C.; Müller-Tidow, C.: Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nature Medicine 23 (1), S. 69 - 78 (2017)
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Pozzi, B.; Bragado, L.; Will, C. L.; Mammi, P.; Risso, G.; Urlaub, H.; Lührmann, R.; Srebrow, A.: SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing. Nucleic Acids Research 45 (11), S. 6729 - 6745 (2017)
95.
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Callegari, S.; Richter, F.; Chojnacka, K.; Jans, D. C.; Lorenzi, I.; Pacheu-Grau, D.; Jakobs, S.; Lenz, C.; Urlaub, H.; Dudek, J. et al.; Chacinska, A.; Rehling, P.: TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Letters 590 (23), S. 4147 - 4158 (2016)
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Strenzke, N.; Chakrabarti, R.; Al-Moyed, H.; Müller, A.; Hoch, G.; Pangrsic, T.; Yamanbaeva, G.; Lenz, C.; Pan, K. T.; Auge, E. et al.; Geiss-Friedlander, R.; Urlaub, H.; Brose, N.; Wichmann, C.; Reisinger, E.: Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants. EMBO Journal 35 (23), S. 2519 - 2535 (2016)
97.
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Zhang, J. N.; Michel, U.; Lenz, C.; Friedel, C. C.; Köster, S.; d'Hedouville, Z.; Tönges, L.; Urlaub, H.; Bähr, M.; Lingor, P. et al.; Koch, J. C.: Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration. Scientific Reports 6, 37050 (2016)
98.
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Manno, B.; Oellerich, T.; Schnyder, T.; Corso, J.; Lösing, M.; Neumann, K.; Urlaub, H.; Batista, F. D.; Engelke, M.; Wienands, J.: The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. European Journal of Immunology 46 (11), S. 2520 - 2530 (2016)
99.
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Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), S. 307 - 319 (2016)
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