Zeitschriftenartikel (218)

  1. Zeitschriftenartikel
    Bouter, I.; Dittrich, K.; Wittnam, J. L.; Rezaei-Ghaleh, N.; Pillot, T.; Papot-Coutourier, S.; Lefebvre, T.; Sprenger, F.; Wirths, O.; Zweckstetter, M. et al.; Bayer, T. A.: N-truncated amyloid beta (A beta) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathologica 126 (2), S. 189 - 205 (2013)
  2. Zeitschriftenartikel
    Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6) (2013)
  3. Zeitschriftenartikel
    Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), S. 795 - 813 (2013)
  4. Zeitschriftenartikel
    Zweckstetter, M.: Conserved amyloid core structure of stop mutants of the human prion protein. Prion 7 (3), S. 193 - 197 (2013)
  5. Zeitschriftenartikel
    Munari, F.; Rezaei-Ghaleh, N.; Xiang, S. Q.; Fischle, W.; Zweckstetter, M.: Structural plasticity in human heterochromatin protein 1 beta. PLoS One 8 (4) (2013)
  6. Zeitschriftenartikel
    Jaremko, M.; Jaremko, L.; Kim, H. Y.; Cho, M. K.; Schwieters, C. D.; Giller, K.; Becker, S.; Zweckstetter, M.: Cold denaturation of a protein dimer monitored at atomic resolution. Nature Chemical Biology 9 (4), S. 264 - 270 (2013)
  7. Zeitschriftenartikel
    Jinwal, U. K.; Akoury, E.; Abisambra, J. F.; O'Leary, J. C.; Thompson, A. D.; Blair, L. J.; Jin, Y.; Bacon, J.; Nordhues, B. A.; Cockman, M. et al.; Zhang, J.; Li, P.; Zhang, B.; Borysov, S.; Uversky, V. N.; Biernat, J.; Mandelkow, E.; Gestwicki, J. E.; Zweckstetter, M.; Dickey, C. A.: Imbalance of Hsp70 family variants fosters tau accumulation. FASEB Journal 27 (4), S. 1450 - 1459 (2013)
  8. Zeitschriftenartikel
    Akoury, E.; Pickardt, M.; Gajda, M. J.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation. Angewandte Chemie-International Edition 52 (12), S. 3511 - 3515 (2013)
  9. Zeitschriftenartikel
    Xiang, S. Q.; Narayanan, R. L.; Becker, S.; Zweckstetter, M.: N-H spin-spin couplings: Probing hydrogen bonds in proteins. Angewandte Chemie-International Edition 52 (12), S. 3525 - 3528 (2013)
  10. Zeitschriftenartikel
    Skora, L.; Fonseca, L.; Hofele, R. V.; Riedel, D.; Giller, K.; Watzlawik, J.; Schulz-Schaeffer, W. J.; Urlaub, H.; Becker, S.; Zweckstetter, M.: Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. Journal of Biological Chemistry 288 (5) (2013)
  11. Zeitschriftenartikel
    Akoury, E.; Gajda, M.; Pickhardt, M.; Biernat, J.; Pornsuwan, S.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Inhibition of tau filament formation by conformational modulation. Journal of the American Chemical Society 135 (7), S. 2853 - 2862 (2013)
  12. Zeitschriftenartikel
    Skora, L.; Zweckstetter, M.: Determination of amyloid core structure using chemical shifts. Protein Science 21 (12), S. 1948 - 1953 (2012)
  13. Zeitschriftenartikel
    Kroth, H.; Ansaloni, A.; Varisco, Y.; Jan, A.; Sreenivasachary, N.; Rezaei-Ghaleh, N.; Giriens, V.; Lohmann, S.; López-Deber, M. P.; Adolfsson, O. et al.; Pihlgren, M.; Paganetti, P.; Froestl, W.; Nagel-Steger, L.; Willbold, D.; Schrader, T.; Zweckstetter, M.; Pfeifer, A.; Lashuel, H. A.; Muhs, A.: Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. Journal of Biological Chemistry 287 (41), S. 34786 - 34800 (2012)
  14. Zeitschriftenartikel
    Munari, F.; Soeroes, S.; Zenn, H. M.; Schomburg, A.; Kost, N.; Schröder, S.; Klingberg, R.; Rezaei-Ghaleh, N.; Stützer, A.; Gelato, K. A. et al.; Walla, P. J.; Becker, S.; Schwarzer, D.; Zimmermann, B.; Fischle, W.; Zweckstetter, M.: Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287 (40), S. 33756 - 33765 (2012)
  15. Zeitschriftenartikel
    El-Turk, F.; Fauvet, B.; Ashrafi, A.; Ouertatani-Sakouhi, H.; Cho, M. K.; Neri, M.; Cascella, M.; Rothlisberger, U.; Pojer, F.; Zweckstetter, M. et al.; Lashuel, H.: Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: Leucine 46 hydrophobic pocket. PLoS One 7 (9) (2012)
  16. Zeitschriftenartikel
    Zachariae, U.; Schneider, R.; Briones, R.; Gattin, Z.; Demers, J. P.; Giller, K.; Maier, E.; Zweckstetter, M.; Griesinger, C.; Becker, S. et al.; Benz, R.; de Groot, B. L.; Lange, A.: Beta-barrel mobility underlies closure of the voltage-dependent anion channel. Structure 20 (9), S. 1540 - 1549 (2012)
  17. Zeitschriftenartikel
    Cho, M. K.; Xiang , S.; Kim, H. Y.; Becker, S.; Zweckstetter, M.: Cold-induced changes in the protein ubiquitin. PLoS One 7 (6) (2012)
  18. Zeitschriftenartikel
    Petroi, D.; Popova, B.; Taheri-Talesh, N.; Irniger, S.; Shapasandzadeh, H.; Zweckstetter, M.; Outeiro, T. F.; Braus, G. H.: Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. Journal of Biological Chemistry 287 (33) (2012)
  19. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Blackledge, M.; Zweckstetter, M.: Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. ChemBioChem 13 (7), S. 930 - 950 (2012)
  20. Zeitschriftenartikel
    Taschenberger, G.; Garrido, M.; Tereshchenko, Y.; Baehr, M.; Zweckstetter, M.; Kuegler, S.: Aggregation of alpha Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathologica 123 (5), S. 671 - 683 (2012)
  21. Zeitschriftenartikel
    Berger, R.; Courtieu, J.; Gil, R. R.; Griesinger, C.; Köck, M.; Lesot, P.; Luy, B.; Merlet, D.; Navarro-Vazquez, A.; Reggelin, M. et al.; Reinscheid, U. M.; Thiele, C. M.; Zweckstetter, M.: Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?—A critical assessment. Angewandte Chemie International Edition 51 (33), S. 8388 - 8391 (2012)
  22. Zeitschriftenartikel
    Daebel, V.; Chinnathambi, S.; Biernat, J.; Schwalbe, M.; Habenstein, B.; Loquet, A.; Akoury, E.; Tepper, K.; Mueller, H.; Baldus, M. et al.; Griesinger, C.; Zweckstetter, M.; Mandelkow, E.; Vijayan, V.; Lange, A.: β-sheet core of Tau paired helical filaments revealed by solid-state NMR. Journal of the American Chemical Society 134 (34), S. 13982 - 13989 (2012)
  23. Zeitschriftenartikel
    Ozenne, V.; Schneider, R.; Yao, M.; Huang, J.-R.; Salmon, L.; Zweckstetter, M.; Jensen, M. R.; Blackledge, M.: Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. Journal of the American Chemical Society 134 (36), S. 15138 - 15148 (2012)
  24. Zeitschriftenartikel
    Bibow, S.; Ozenne, V.; Biernat, J.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133 (40), S. 15842 - 15845 (2011)
  25. Zeitschriftenartikel
    Lamberto, C. R.; Torres-Monserrat, V.; Bertoncini, C. W.; Salvatella, X.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly. Journal of Biological Chemistry 286 (37), S. 32036 - 32044 (2011)
  26. Zeitschriftenartikel
    Balija, M. B. G.; Griesinger, C.; Herzig, A.; Zweckstetter, M.; Jäckle, H.: Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9) (2011)
  27. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Zweckstetter, M.: Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), S. 1202 - 1211 (2011)
  28. Zeitschriftenartikel
    Luo, L.; Hannemann, M.; Koenig, S.; Hegermann, J.; Ailion, M.; Cho, M. K.; Sasidharan, N.; Zweckstetter, M.; Rensing, S. A.; Eimer, S.: The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), S. 2564 - 2578 (2011)
  29. Zeitschriftenartikel
    Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H. H.; Bossis, G.; Urlaub, H.; Zweckstetter, M.; Kuegler, S.; Melchior, F. et al.; Baehr, M.; Weishaupt, J. H.: Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), S. 49 - 60 (2011)
  30. Zeitschriftenartikel
    Kumar, S.; Rezaei-Ghaleh, N.; Terwel, D.; Thal, D. R.; Richard, M.; Hoch, M.; McDonald, J. M.; Wuellner, U.; Glebov, K.; Heneka, M. T. et al.; Walsh, D. M.; Zweckstetter, M.; Walter, J.: Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), S. 2255 - 2265 (2011)
  31. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Andreetto, E.; Yan, L. M.; Kapurniotu, A.; Zweckstetter, M.: Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5) (2011)
  32. Zeitschriftenartikel
    Cho, M. K.; Kim, H. Y.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), S. 387 - 395 (2011)
  33. Zeitschriftenartikel
    Binolfi, A.; Valiente-Gabioud, A. A.; Duran, R.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), S. 194 - 196 (2011)
  34. Zeitschriftenartikel
    Bibow, S.; Mukrasch, M. D.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), S. 11520 - 11524 (2011)
  35. Zeitschriftenartikel
    Gruene, T.; Cho, M. K.; Karyagina, I.; Kim, H. Y.; Grosse, C.; Giller, K.; Zweckstetter, M.; Becker, S.: Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), S. 111 - 119 (2011)
  36. Zeitschriftenartikel
    Villinger, S.; Briones, R.; Giller, K.; Zachariä, U.; Lange, A.; de Groot, B. L.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), S. 22546 - 22551 (2010)
  37. Zeitschriftenartikel
    Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), S. 10668 - 10679 (2010)
  38. Zeitschriftenartikel
    de la Cruz, L.; Bajaj, R.; Becker, S.; Zweckstetter, M.: The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences. Protein Science 19 (11), S. 2045 - 2054 (2010)
  39. Zeitschriftenartikel
    Skora, L.; Becker, S.; Zweckstetter, M.: Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR. ChemBioChem 11 (13), S. 1829 - 1832 (2010)
  40. Zeitschriftenartikel
    Narayanan, R.L.; Dürr, U. H. N.; Bibow, S.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Automatic assignment of the intrinsically disordered protein Tau with 441-residues. Journal of the American Chemical Society 132 (34), S. 11906 - 11907 (2010)
  41. Zeitschriftenartikel
    Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Cho, M. K.; Karpinar, D. P.; Le Roy, D.; Dewor, M.; Roger, T.; Bernhagen, J.; Calandra, T. et al.; Zweckstetter, M.; Lashuel, H. A.: Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. Journal of Biological Chemistry 285 (34), S. 26581 - 26598 (2010)
  42. Zeitschriftenartikel
    Shoshan-Barmatz, V.; De Pinto, V.; Zweckstetter, M.; Raviv, Z.; Keinan, N.; Arbel, N.: VDAC, a multi-functional mitochondrial protein regulating cell life and death. Molecular Aspects of Medicine 31 (3), S. 227 - 285 (2010)
  43. Zeitschriftenartikel
    Di Giovanni, S.; Eleuteri, S.; Paleologou, K. E.; Yin, G.; Zweckstetter, M.; Carrupt, P. A.; Lashuel, H. A.: Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry 285 (20), S. 14941 - 14954 (2010)
  44. Zeitschriftenartikel
    Paleologou, K. E.; Oueslati, A.; Shakked, G.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fernandez, C. O.; Schmid, A.; Chegini, F.; Gai, W. P. et al.; Chiappe, D.; Moniatte, M.; Schneider, B. L.; Aebischer, P.; Eliezer, D.; Zweckstetter, M.; Masliah, E.; Lashuel, H. A.: Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), S. 3184 - 3198 (2010)
  45. Zeitschriftenartikel
    Schneider, R.; Etzkorn, M.; Giller, K.; Daebel, V.; Eisfeld, J.; Zweckstetter, M.; Griesinger, C.; Becker, S.; Lange, A.: The native conformation of the human VDAC1 N terminus. Angewandte Chemie - International Edition 49 (10), S. 1882 - 1885 (2010)
  46. Zeitschriftenartikel
    Mbefo, M. K.; Paleologou, K. E.; Boucharaba, A.; Oueslati, A.; Schell, H.; Fournier, M.; Olschewski, D.; Yin, G.; Zweckstetter, M.; Masliah, E. et al.; Kahle, P. J.; Hirling, H.; Lashuel, H. A.: Phosphorylation of synucleins by members of the polo-like kinase family. Journal of Biological Chemistry 285 (4), S. 2807 - 2822 (2010)
  47. Zeitschriftenartikel
    Salmon, L.; Nodet, G.; Oezenne, V.; Yin, G.; Jensen, M. R.; Zweckstetter, M.; Blackledge, M.: NMR characterization of long-range order in intrinsically disordered proteins. Journal of the American Chemical Society 132 (24), S. 8407 - 8418 (2010)
  48. Zeitschriftenartikel
    Skora, L.; Becker, S.; Zweckstetter, M.: Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin. Journal of the American Chemical Society 132 (27), S. 9223 - 9225 (2010)
  49. Zeitschriftenartikel
    Lamberto, G. R.; Binolfi, A.; Orcelett, M. L.; Bertoncini, C. O.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), S. 21057 - 21062 (2009)
  50. Zeitschriftenartikel
    Kim, H. Y.; Cho, M. K.; Kumar, A.; Maier, E.; Siebenhaar, C.; Becker, S.; Fernandez, C. O.; Lashuel, H. A.; Benz, R.; Lange, A. et al.; Zweckstetter, M.: Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), S. 17482 - 17489 (2009)
  51. Zeitschriftenartikel
    Fischer, D.; Mukrasch, M. D.; Biernat, J.; Bibow, S.; Blackledge, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules. Biochemistry 48 (42), S. 10047 - 10055 (2009)
  52. Zeitschriftenartikel
    Jensen, M. R.; Markwick, P. R.; Meier, S.; Griesinger, C.; Zweckstetter, M.; Grzesiek, S.; Bernado, P.; Blackledge, M.: Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure 17 (9) (2009)
  53. Zeitschriftenartikel
    Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T. et al.; Lashuel, H. A.: A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry 48 (41), S. 9858 - 9870 (2009)
  54. Zeitschriftenartikel
    Cho, M. K.; Nodet, G.; Kim, H. K.; Jensen, M. R.; Bernado, P.; Fernandez, C. O.; Becker, S.; Blackledge, M.; Zweckstetter, M.: Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), S. 1840 - 1846 (2009)
  55. Zeitschriftenartikel
    Karpinar, P.; Gajula Balija, M. B.; Kügler, S.; Opazo, F.; Rezaei-Ghaleh, N.; Wender, N.; Kim, H. Y.; Taschenberger, G.; Falkenburger, B. H.; Heise, H. et al.; Kumar, A.; Riedel, D.; Fichtner, L.; Voigt, A.; Braus, G. H.; Giller, K.; Becker, S.; Herzig, A.; Baldus, M.; Jäckle, H.; Eimer, S.; Schulz, J. B.; Griesinger, C.; Zweckstetter, M.: Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), S. 3256 - 3268 (2009)
  56. Zeitschriftenartikel
    Mukrasch, M.; Bibow, S.; Korukottu, J.; Jeganathan, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)
  57. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nehmat-Gorgani, M.: Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), S. 28 - 36 (2009)
  58. Zeitschriftenartikel
    Coudevylle, N.; Montaville, P.; Leonov, M.; Zweckstetter, M.; Becker, S.: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), S. 35918 - 35928 (2008)
  59. Zeitschriftenartikel
    Rumpel, S.; Lakshmi, R.; Becker, S.; Zweckstetter, M.: Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), S. 2015 - 2019 (2008)
  60. Zeitschriftenartikel
    Soragni, A.; Zambelli, B.; Mukrasch, M.; Biernat, J.; Jeganathan, S.; Griesinger, C.; Ciurli, S.; Mandelkow, E.; Zweckstetter, M.: Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), S. 10841 - 10851 (2008)
  61. Zeitschriftenartikel
    Bayrhuber, M.; Meins, T.; Habeck, M.; Becker, S.; Giller, K.; Villinger, S.; Vonrhein, C.; Griesinger, C.; Zweckstetter, M.; Zeth, K.: Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), S. 15370 - 15375 (2008)
  62. Zeitschriftenartikel
    El-Turk, F.; Cascella, M.; Ouertatami-Sakonhi, H.; Lakshmi, R. N.; Leng, L.; Bucala, R.; Zweckstetter, M.; Rothlisberger, U.; Lashuel, H. A.: The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), S. 10740 - 10756 (2008)
  63. Zeitschriftenartikel
    Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), S. 11801 - 11812 (2008)
  64. Zeitschriftenartikel
    Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), S. 5046 - 5048 (2008)
  65. Zeitschriftenartikel
    Korukottu, J.; Schneider, R.; Vijayan, V.; Lange, A.; Pongs, O.; Becker, S.; Baldus, M.; Zweckstetter, M.: High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)
  66. Zeitschriftenartikel
    Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, S. 16895 - 16905 (2008)
  67. Zeitschriftenartikel
    Sevvana, M.; Vijayan, V.; Zweckstetter, M.; Reinelt, S.; Madden, D. R.; Herbst-Irmer, R.; Sheldrick, G. M.; Bott, M.; Griesinger, C.; Becker, S.: A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), S. 512 - 523 (2008)
  68. Zeitschriftenartikel
    Zweckstetter, M.: NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), S. 679 - 690 (2008)
  69. Zeitschriftenartikel
    Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), S. 1025 - 1034 (2008)
  70. Zeitschriftenartikel
    Rumpel, S.; Becker, S.; Zweckstetter, M.: High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), S. 1 - 13 (2008)
  71. Zeitschriftenartikel
    Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), S. 708 - 722 (2007)
  72. Zeitschriftenartikel
    Mukrasch, M.; von Bergen, M.; Biernat, J.; Fischer, D.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), S. 12230 - 12239 (2007)
  73. Zeitschriftenartikel
    Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), S. 3032 - 3033 (2007)
  74. Zeitschriftenartikel
    Fischer, D.; Mukrasch, M.; von Bergen, M.; Klos-Witkowska, A.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), S. 2574 - 2582 (2007)
  75. Zeitschriftenartikel
    Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), S. 5015 - 5025 (2007)
  76. Zeitschriftenartikel
    Kim, H. Y.; Heise, H.; Fernandez, C. O.; Baldus, M.; Zweckstetter, M.: Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein. ChemBioChem 8 (14), S. 1671 - 1674 (2007)
  77. Zeitschriftenartikel
    Korukottu, J.; Bayrhuber, M.; Montaville, P.; Jung, Y. S.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Fast high-resolution protein structure determination by using unassigned NMR data. Angewandte Chemie International Edition 46 (7), S. 1176 - 1179 (2007)
  78. Zeitschriftenartikel
    Mukrasch, M.; Markwick, P.; Biernat, J.; von Bergen, M.; Bernado, P.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.; Blackledge, M.: Highly populated turn conformations in natively unfolded Tau protein identified from residual dipolar couplings and molecular simulation. Journal of the American Chemical Society 129 (16), S. 5235 - 5243 (2007)
  79. Zeitschriftenartikel
    Iwahara, J.; Zweckstetter, M.; Clore, G. M.: NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. Proceedings of the National Academy of Sciences of the United States of America 103 (41), S. 15062 - 15067 (2006)
  80. Zeitschriftenartikel
    Watzlawik, J.; Skora, L.; Frense, D.; Griesinger, C.; Zweckstetter, M.; Schulz-Schaeffer, W.; Kramer, M. L.: Prion protein helix1 promotes aggregation but is not converted into beta-sheet. Journal of Biological Chemistry 281 (40), S. 30242 - 30250 (2006)
  81. Zeitschriftenartikel
    Ab, E.; Atkinson, A. R.; Banci, L.; Bertini, I.; Ciofi-Baffoni, S.; Brunner, K.; Diercks, T.; Dötsch, V.; Engelke, F.; Folkers, G. E. et al.; Griesinger, C.; Gronwald, W.; Günther, U.; Habeck, M.; De Jong, R. N.; Kalbitzer, H. R.; Kieffer, B.; Leeflang, B. R.; Loss, S.; Luchinat, C.; Marquardsen, T.; Moskau, D.; Neidig, K. P.; Nilges, M.; Piccioli, M.; Pierattelli, R.; Rieping, W.; Schippmann, T.; Schwalbe, H.; Travé, G.; Trenner, J.; Wöhnert, J.; Zweckstetter, M.; Kaptein, R.: NMR in the SPINE structural proteomics project. Acta Crystallographica Section D-Biological Crystallography 62 (10), S. 1150 - 1161 (2006)
  82. Zeitschriftenartikel
    Jauch, R.; Cho, M. K.; Jaekel, S.; Netter, C.; Schreiter, K.; Aicher, B.; Zweckstetter, M.; Jaeckle, H.; Wahl, M. C.: Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. The EMBO Journal 25 (17), S. 4020 - 4032 (2006)
  83. Zeitschriftenartikel
    Binolfi, A.; Rasia, R. M.; Bertoncini, C. W.; Ceolin, M.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement. Journal of the American Chemical Society 128 (30), S. 9893 - 9901 (2006)
  84. Zeitschriftenartikel
    Bayrhuber, M.; Graf, R.; Ferber, M.; Zweckstetter, M.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Becker, S.: Production of recombinat Conkunitzin-S1 in Escherichia coli. Protein Expression and Purification 47 (2), S. 640 - 644 (2006)
  85. Zeitschriftenartikel
    Skora, L.; Cho, M. K.; Kim, H. Y.; Becker, S.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Charge-induced molecular alignment of intrinsically disordered proteins. Angewandte Chemie-International Edition 45 (42), S. 7012 - 7015 (2006)
  86. Zeitschriftenartikel
    Zweckstetter, M.: Prediction of charge-induced molecular alignment: Residual dipolar couplings at pH 3 and alignment in surfactant liquid crystalline phases. European Biophysics Journal 35 (2), S. 170 - 180 (2006)
  87. Zeitschriftenartikel
    Bertoncini, C. W.; Fernandez, C. O.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. Journal of Biological Chemistry 280, S. 30649 - 30652 (2005)
  88. Zeitschriftenartikel
    Schnell, J. R.; Zhou, G. P.; Zweckstetter, M.; Rigby, A. C.; Chou, J. J.: Rapid and accurate structure determination of coiled-coil domains using NMR dipolar couplings: Application to cGMP-dependent protein kinase I alpha. Protein Science 14 (9), S. 2421 - 2428 (2005)
  89. Zeitschriftenartikel
    Zweckstetter, M.; Schnell, J. R.; Chou, J. J.: Determination of the packing mode of the coiled-coil domain of cGMP-dependent protein kinase I alpha in solution using charge-predicted dipolar couplings. Journal of the American Chemical Society 127 (34), S. 11918 - 11919 (2005)
  90. Zeitschriftenartikel
    Mukrasch, M.; Biernat, J.; von Bergen, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Sites of tau important for aggregation populate beta-structure and bind to microtubules and polyanions. Journal of Biological Chemistry 280 (26), S. 24978 - 24986 (2005)
  91. Zeitschriftenartikel
    Bayrhuber, M.; Vijayan, V.; Ferber, M.; Graf, R.; Korukottu, J.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Zweckstetter, M. et al.; Becker, S.: Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family - Structural and functional characterization. Journal of Biological Chemistry 280 (25), S. 23766 - 23770 (2005)
  92. Zeitschriftenartikel
    Vijayan, V.; Zweckstetter, M.: Simultaneous measurement of protein one-bond residual dipolar couplings without increased resonance overlap. Journal of Magnetic Resonance 174 (2), S. 245 - 253 (2005)
  93. Zeitschriftenartikel
    Kneuper, H.; Janausch, I. G.; Vijayan, V.; Zweckstetter, M.; Bock, V.; Griesinger, C.; Unden, G.: The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. Journal of Biological Chemistry 280 (21), S. 20596 - 20603 (2005)
  94. Zeitschriftenartikel
    Rumpel, S.; Kim, H. Y.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Letter to the editor: Backbone resonance assignment of the homodimeric, 35 kDa chaperone CesT from enteropathogenic Escherichia coli. Journal of Biomolecular NMR 31 (4), S. 377 - 378 (2005)
  95. Zeitschriftenartikel
    Rasia, R. M.; Bertoncini, C. W.; Marsh, D.; Hoyer, W.; Cherny, D. I.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Structural characterization of copper(II) binding to α-Synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 102, 10.1073/pnas.0407881102, S. 4294 - 4299 (2005)
  96. Zeitschriftenartikel
    Bertoncini, C. W.; Jung, Y. S.; Fernandez, C. O.; Hoyer, W.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein. Proceedings of the National Academy of Sciences of the United States of America 102 (5), S. 1430 - 1435 (2005)
  97. Zeitschriftenartikel
    Bernado, P.; Bertonconi, C. W.; Griesinger, C.; Zweckstetter, M.; Blackledge, M.: Defining long-range order and local disorder in native α-synuclein using residual dipolar couplings. Journal of the American Chemical Society 127 (51), S. 17968 - 17969 (2005)
  98. Zeitschriftenartikel
    Rumpel, S.; Razeto, A.; Pillar, C. M.; Vijayan, V.; Taylor, A.; Giller, K.; Gilmore, M. S.; Becker, S.; Zweckstetter, M.: Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis. EMBO Journal 23 (18), S. 3632 - 3642 (2004)
  99. Zeitschriftenartikel
    Jung, Y. S.; Zweckstetter, M.: Mars - robust automatic backbone assignment of proteins. Journal of Biomolecular NMR 30 (1), S. 11 - 23 (2004)
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