Zeitschriftenartikel (214)

  1. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Parigi, G.; Zweckstetter, M.: Reorientational dynamics of amyloid-β from NMR spin relaxation and molecular simulation. Journal of Physical Chemistry Letters 10 (2019)
  2. Zeitschriftenartikel
    Albert, N. L.; Unterrainer, M.; Brendel, M.; Kaiser, L.; Zweckstetter, M.; Cumming, P.; Bartenstein, P.: In response to: The validity of 18F-GE180 as a TSPO imaging agent. European Journal of Nuclear Medicine and Molecular Imaging 46 (6), S. 1208 - 1211 (2019)
  3. Zeitschriftenartikel
    Albert, N. L.; Unterrainer, M.; Brendel, M.; Kaiser, L.; Zweckstetter, M.; Cumming, P.; Bartenstein, P.: In response to: The validity of F-18-GE180 as a TSPO imaging agent. European Journal of Nuclear Medicine and Molecular Imaging 46 (6), S. 1208 - 1211 (2019)
  4. Zeitschriftenartikel
    Gong, J.; Szego, E. M.; Leonov, A.; Benito, E.; Becker, S.; Fischer, A.; Zweckstetter, M.; Outeiro, T.; Schneider, A.: Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 39 (19), S. 3752 - 3769 (2019)
  5. Zeitschriftenartikel
    Mavroeidi, P.; Arvanitaki, F.; Karakitsou, A. K.; Vetsi, M.; Kloukina, I.; Zweckstetter, M.; Giller, K.; Becker, S.; Sorrentino, Z. A.; Giasson, B. I. et al.; Jensen, P. H.; Stefanis, L.; Xilouri, M.: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica (2019)
  6. Zeitschriftenartikel
    Melková, K.; Zapletal, V.; Narasimhan, S.; Jansen, S.; Hritz, J.; Škrabana, R.; Zweckstetter, M.; Ringkjøbing-Jensen, M.; Blackledge, M.; Žídek, L.: Structure and functions of microtubule associated proteins tau and MAP2c: Similarities and differences. Biomolecules 9 (3) (2019)
  7. Zeitschriftenartikel
    Gonzalez-Magana, A.; Ibanez de Opakua, A.; Romano-Moreno, M.; Murciano-Calles, J.; Merino, N.; Luque, I.; Rojas, A. L.; Onesti, S.; Blanco, F. J.; De Biasio, A.: The p12 subunit of human polymerase uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA). Journal of Biological Chemistry 294 (11), S. 3947 - 3956 (2019)
  8. Zeitschriftenartikel
    Rankovic, M.; Zweckstetter, M.: Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-Protein in children with neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews 98, S. 1 - 9 (2019)
  9. Zeitschriftenartikel
    Jaipuria, G.; Giller, K.; Leonov, A.; Becker, S.; Zweckstetter, M.: Insights into cholesterol/membrane protein interactions using paramagnetic solid-state NMR. Chemistry - A European Journal 24 (66), S. 17606 - 17611 (2018)
  10. Zeitschriftenartikel
    Pellkofer, H.; Ihler, F.; Weiss, B. G.; Trothe, J.; Kadavath, H.; Chongtham, M.; Kunadt, M.; Riedel, D.; Lornsen, F.; Wilken, P. et al.; Bartels, C.; Hirschel, S.; Russo, S. G.; Stransky, E.; Trojan, L.; Schmidt, B.; Mandelkow, E.; Zweckstetter, M.; Canis, M.; Schneider, A.: Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa. European Archives of Psychiatry and Clinical Neuroscience (2018)
  11. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Parigi, G.; Soranno, A.; Holla, A.; Becker, S.; Schuler, B.; Luchinat, C.; Zweckstetter, M.: Local and global dynamics in intrinsically disordered synuclein. Angewandte Chemie International Edition 57 (46), S. 15262 - 15266 (2018)
  12. Zeitschriftenartikel
    Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9 (2018)
  13. Zeitschriftenartikel
    Gentile, I.; Garro, H. A.; Delgado Ocaña, S.; Gonzalez, N.; Strohäker, T.; Schibich, D.; Quintanar, L.; Sambrotta, L.; Zweckstetter, M.; Griesinger, C. et al.; Menacho Márqueza, M.; Fernandez, C. O.: Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: Binding ligands, affinity and structural features. Metallomics 10 (10), S. 1383 - 1389 (2018)
  14. Zeitschriftenartikel
    Jäckl, M.; Stollmaier, C.; Strohäker, T.; Hyz, K.; Maspero, E.; Polo, S.; Wiesner, S.: Beta-sheet augmentation is a conserved mechanism of priming HECT E3 ligases for ubiquitin ligation. Journal of Molecular Biology 430 (18), S. 3218 - 3233 (2018)
  15. Zeitschriftenartikel
    Böhning, M.; Dugast-Darzacq, C.; Rankovic, M.; Hansen, A. S.; Yu, T.; Marie-Nelly, H.; McSwiggen, D. T.; Kokic, G.; Dailey, G. M.; Cramer, P. et al.; Darzacq, X.; Zweckstetter, M.: RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), S. 833 - 840 (2018)
  16. Zeitschriftenartikel
    Melkova, K.; Zapletal, V.; Jansen, S.; Nomilner, E.; Zachrdla, M.; Hritz, J.; Novacek, J.; Zweckstetter, M.; Jensen, M. R.; Blackledge, M. et al.; Zidek, L.: Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics. Journal of Biological Chemistry 293 (34), S. 13297 - 13309 (2018)
  17. Zeitschriftenartikel
    Abayev, M.; Rodrigues, J. P. G. L. M.; Srivastava, G.; Arshava, B.; Jaremko, L.; Jaremko, M.; Naider, F.; Levitt, M.; Anglister, J.: The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5. FEBS Journal 285 (11) (2018)
  18. Zeitschriftenartikel
    Jaipuria, G.; Ukmar-Godec, T.; Zweckstetter, M.: Challenges and approaches to understand cholesterol-binding impact on membrane protein function: An NMR view. Cellular and Molecular Life Sciences 75 (12), S. 2137 - 2151 (2018)
  19. Zeitschriftenartikel
    Aliakbari, F.; Mohammad-Beigi, H.; Rezaei-Ghaleh, N.; Becker, S.; Esmatabad, F. D.; Seyedi, H. A. E.; Bardania, H.; Marvian, A. T.; Collingwood, J. F.; Christiansen, G. et al.; Zweckstetter, M.; Otzen, D. E.; Morshedi, D.: The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale 10 (19), S. 9174 - 9185 (2018)
  20. Zeitschriftenartikel
    Mok, S. A.; Condello, C.; Freilich, R.; Gillies, A.; Arhar, T.; Oroz, J.; Kadavath, H.; Julien, O.; Assimon, V. A.; Rauch, J. N. et al.; Dunyak, B. M.; Lee, J.; Tsai, F. T. F.; Wilson, M. R.; Zweckstetter, M.; Dickey, C. A.; Gestwicki, J. E.: Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nature Structural and Molecular Biology 25 (5), S. 384 - 393 (2018)
  21. Zeitschriftenartikel
    Kadavath, H.; Cabrales-Fontela, Y.; Jaremko, M.; Jaremko, L.; Overkamp, K.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: The binding mode of a repeat-like Tau sequence with tubulin. Angewandte Chemie International Edition 57 (12), S. 3246 - 3250 (2018)
  22. Zeitschriftenartikel
    Tolö, J.; Taschenberger, G.; Leite, K.; Stahlberg, M. A.; Spehlbrink, G.; Kues, J.; Munari, F.; Capaldi, S.; Becker, S.; Zweckstetter, M. et al.; Dean, C.; Bähr, M.; Kügler, S.: Pathophysiological consequences of neuronal alpha-Synuclein overexpression: Impacts on ion homeostasis, stress signaling, mitochondrial integrity, and electrical activity. Frontiers in Molecular Neuroscience 11 (2018)
  23. Zeitschriftenartikel
    Lasorsa, A.; Natile, G.; Rosato, A.; Tadini-Buoninsegni , F.; Arnesano , F.: Monitoring interactions inside cells by advanced spectroscopies: Overview of copper transporters and cisplatin. Current Medicinal Chemistry 25 (4), S. 462 - 477 (2018)
  24. Zeitschriftenartikel
    Martinez Hernandez, A.; Urbanke, H.; Gillman, A. L.; Lee, J.; Ryazanov, S.; Agbemenyah, H. Y.; Benito, E.; Jain, G.; Kaurani, L.; Grigorian, G. et al.; Leonov, A.; Rezaei-Ghaleh, N.; Wilken, P.; Arce, F. T.; Wagner, J.; Fuhrman, M.; Caruana, M.; Camilleri, A.; Vassallo, N.; Zweckstetter, M.; Benz, R.; Giese, A.; Schneider, A.; Korte, M.; Lal, R.; Griesinger, C.; Eichele, G.; Fischer, A.: The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine 10 (1) (2018)
  25. Zeitschriftenartikel
    Cabrales-Fontela, Y.; Kadavath, H.; Biernat, J.; Riedel, D.; Mandelkow, E.; Zweckstetter, M.: Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau. Nature Communications 8 (2017)
  26. Zeitschriftenartikel
    Bharat, V.; Siebrecht, M.; Burk, K.; Ahmed, S.; Reissner, C.; Kohansal-Nodehi, M.; Steubler, V.; Zweckstetter, M.; Ting, J. T.; Dean, C.: Capture of dense core vesicles at synapses by JNK-dependent phosphorylation of Synaptotagmin-4. Cell Reports 21 (8) (2017)
  27. Zeitschriftenartikel
    Fonseca-Ornelas, L.; Schmidt, C. D.; Camacho-Zarco, A. R.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Small molecule-induced soluble oligomers of α-synuclein with helical structure. Chemistry. A European Journal 23 (53), S. 13010 - 13014 (2017)
  28. Zeitschriftenartikel
    Miotto, M. C.; Pavese, M. D.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernández, C. O.: Bioinorganic chemistry of Parkinson's disease: Affinity and structural features of Cu(I) binding to the full-length β-synuclein protein. Inorganic Chemistry 56 (17), S. 10387 - 10395 (2017)
  29. Zeitschriftenartikel
    Ambadipudi, S.; Biernat, J.; Riedel, D.; Mandelkow, E.; Zweckstetter, M.: Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau. Nature Communications 8 (2017)
  30. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Bakhtiari, D.; Rashidi, A.: Reverse allostasis in biological systems: Minimal conditions and implications. Journal of Theoretical Biology 426, S. 134 - 139 (2017)
  31. Zeitschriftenartikel
    Baker, J. D.; Shelton, L. B.; Zheng, D. L.; Favretto, F.; Nordhues, B. A.; Darling, A.; Sullivan, L. E.; Sun, Z. Y.; Solanki, P. K.; Martin, M. D. et al.; Suntharalingam, A.; Sabbagh, J. J.; Becker, S.; Mandelkow, E.; Uversky, V. N.; Zweckstetter, M.; Dickey, C. A.; Koren, J.; Blair, L. J.: Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biology 15 (6) (2017)
  32. Zeitschriftenartikel
    Vincente Miranda, H.; Szego, E. M.; Oliveira, L. M.; Breda, C.; Darendelioglu, E.; de Oliveira, R. M.; Ferreira, D. G.; Gomes, M. A.; Rott, R.; Oliveira, M. et al.; Munari, F.; Enguita, F. J.; Simoes, T.; Rodrigues, E. F.; Heinrich, M.; Martins, I. C.; Zamolo, I.; Riess, O.; Cordeiro, C.; Ponces-Freire, A.; Lashuel, H. A.; Santos, N. C.; Lopes, L. V.; Xiang, W.; Jovin, T. M.; Penque, D.; Engelender, S.; Zweckstetter, M.; Klucken, J.; Giorgini, F.; Quintas, A.; Outeiro, T. F.: Glycation potentiates alpha-synuclein-associated neurodegeneration in synucleinopathies. Brain 140 (5), S. 1399 - 1419 (2017)
  33. Zeitschriftenartikel
    Zweckstetter, M.; Requena, J. R.; Wille, H.: Elucidating the structure of an infectious protein. PLoS Pathogens 13 (4) (2017)
  34. Zeitschriftenartikel
    Oroz, J.; Kim, J. H.; Chang, B. J.; Zweckstetter, M.: Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90. Nature Structural and Molecular Biology 24 (4), S. 407 - 413 (2017)
  35. Zeitschriftenartikel
    de Oliveira, R. M.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegö, E. M.; Martinho, R.; Munari, F.; Lázaro, D. F.; Moniot, S.; Guerreiro, P. et al.; Fonseca, L.; Marijanovic, Z.; Antas, P.; Gerhardt, E.; Enguita, F. J.; Fauvet, B.; Penque, D.; Pais, T. F.; Tong, Q.; Becker, S.; Kügler, S.; Lashuel, H. A.; Steegborn, C.; Zweckstetter, M.; Outeiro, T. F.: The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 15 (3) (2017)
  36. Zeitschriftenartikel
    Kim, J. H.; Oroz, J.; Zweckstetter, M.: Structure of monomeric transthyretin carrying the clinically important T119M mutation. Angewandte Chemie International Edition 55 (52), S. 16168 - 16171 (2016)
  37. Zeitschriftenartikel
    Marsh, D.: Nuclear spin-lattice relaxation in nitroxide spin-label EPR. Journal of Magnetic Resonance 272, S. 166 - 171 (2016)
  38. Zeitschriftenartikel
    Villar-Piquéa, A.; da Fonsecaa, T. L.; Sant’Annab, R.; Szegöa, E. M.; Fonseca-Ornelas, L.; Pinhoa, R.; Carijac, A.; Gerhardta, E.; Masaracchiaa, C.; Gonzalezf, E. A. et al.; Rossettif, G.; Carlonif, P.; Fernándezi, C. O.; Foguelb, D.; Milosevick, I.; Zweckstetter, M.; Venturac, S.; Outeiro, T. F.: Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 113 (42), S. E6506 - E6515 (2016)
  39. Zeitschriftenartikel
    Villar-Piqué, A.; da Fonseca, T. L.; Sant’Anna, R.; Szegö, E. M.; Fonseca-Ornelas, L.; Pinho, R.; Carija, A.; Gerhardt, E.; Masaracchia, C.; Gonzalezf, E. A. et al.; Rossetti, G.; Carloni, P.; Fernández, C. O.; Foguel, D.; Milosevic, I.; Zweckstetter, M.; Ventura, S.; Outeiro, T. F.: Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of Amerca 113 (42) (2016)
  40. Zeitschriftenartikel
    Briones, R.; Weichbrodt, C.; Paltrinieri, L.; Mey, I.; Villinger, S.; Giller, K.; Lange, A.; Zweckstetter, M.; Griesinger, C.; Becker, S. et al.; Steinem, C.; de Groot, B. L.: Voltage dependence of conformational dynamics and subconducting states of VDAC-1. Biophysical Journal 111 (6), S. 1223 - 1234 (2016)
  41. Zeitschriftenartikel
    Jaremko, M.; Jaremko, L.; Villinger, S.; Schmidt, C. D.; Griesinger, C.; Becker, S.; Zweckstetter, M.: High-resolution NMR determination of the dynamic structure of membrane proteins. Angewandte Chemie International Edition 55 (35), S. 101518 - 10521 (2016)
  42. Zeitschriftenartikel
    Fonseca-Ornelas, L.; Zweckstetter, M.: The protonation state of histidine 111 regulates the aggregation of the evolutionary most conserved region of the human prion protein. Protein Science 25 (8), S. 1563 - 1567 (2016)
  43. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Kumar, S.; Walter, J.; Zweckstetter, M.: Phosphorylation interferes with maturation of amyloid-β fibrillar structure in the N terminus. Journal of Biological Chemistry 291 (31), S. 16059 - 16067 (2016)
  44. Zeitschriftenartikel
    Beyer, I.; Rezaei-Ghaleh, N.; Klafki, H. W.; Jahn, O.; Haussmann, U.; Wiltfang, J.; Zweckstetter, M.; Knölker, H. J.: Solid-phase synthesis and characterization of N-terminally elongated A beta(-3-x)-peptides. Chemistry-A European Journal 22 (25), S. 8685 - 8693 (2016)
  45. Zeitschriftenartikel
    Akoury, E.; Mukrasch, M.; Biernat, J.; Tepper, K.; Ozenne, V.; Mandelkow, E.; Blackledge, M.; Zweckstetter, M.: Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer. Protein Science 25 (5), S. 1010 - 1020 (2016)
  46. Zeitschriftenartikel
    Tatenhorst, L.; Eckermann, K.; Dambeck, V.; Fonseca-Ornelas, L.; Walle, H.; da Fonseca, T. L.; Koch, J. C.; Becker, S.; Toenges, L.; Bahr, M. et al.; Outeiro, T. F.; Zweckstetter, M.; Lingor, P.: Fasudil attenuates aggregation of alpha-synuclein in models of Parkinson's disease. Acta Neuropathologica Communications 4 (2016)
  47. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Amininasab, M.; Kumar, S.; Walter , J.; Zweckstetter, M.: Phosphorylation modifies the molecular stability of beta-amyloid deposits. Nature Communications 7 (2016)
  48. Zeitschriftenartikel
    Ge, L.; Villinger, S.; Mari, S. A.; Giller, K.; Griesinger, C.; Becker, S.; Müller, D. J.; Zweckstetter, M.: Molecular plasticity of the human Voltage-Dependent Anion Channel embedded into a membrane. Structure 24 (4), S. 585 - 594 (2016)
  49. Zeitschriftenartikel
    Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S.; Zweckstetter, M.: Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand. Biomolecular NMR Assignments 10 (1), S. 79 - 83 (2016)
  50. Zeitschriftenartikel
    Kumar, S.; Wirths, O.; Stüber, K.; Wunderlich, P.; Koch, P.; Theil, S.; Rezaei-Ghaleh, N.; Zweckstetter, M.; Bayer, T. A.; Bruestle, O. et al.; Thal, D. R.; Walter, J.: Phosphorylation of the amyloid beta-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity. Acta Neuropathologica 131 (4), S. 525 - 537 (2016)
  51. Zeitschriftenartikel
    Tenreiro, S.; Rosado-Ramos, R.; Gerhardt, E.; Favretto, F.; Magalhães, F.; Popova, B.; Becker, S.; Zweckstetter, M.; Braus, G. H.; Outeiro, T. F.: Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Human Molecular Genetics 25 (2), S. 275 - 290 (2016)
  52. Zeitschriftenartikel
    Ambadipudi, S.; Zweckstetter, M.: Targeting intrinsically disordered proteins in rational drug discovery. Expert Opinion on Drug Discocery 11 (1), S. 65 - 77 (2016)
  53. Zeitschriftenartikel
    Wysoczanski, P.; Zweckstetter, M.: Retention and splicing complex (RES) - the importance of cooperativity. RNA Biology 13 (2), S. 128 - 133 (2016)
  54. Zeitschriftenartikel
    Moree, B.; Yin, G.; Lazaro, D. F.; Munari, F.; Strohäker, T.; Giller, K.; Becker, S.; Outeiro, T. F.; Zweckstetter, M.; Salafsky, J.: Small molecules detected by second-harmonic generation modulate the conformation of monomeric α-synuclein and reduce its aggregation in cell. Journal of Biological Chemistry 290 (46) (2015)
  55. Zeitschriftenartikel
    Rauscher, S.; Gapsys, V.; Gajda, M. J.; Zweckstetter, M.; de Groot, B. L.; Grubmüller, H.: Structural ensembles of intrinsically disordered proteins depend strongly on force field: A comparison to experiment. Journal of Chemical Theory and Computation 11 (11), S. 5513 - 5524 (2015)
  56. Zeitschriftenartikel
    Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S.; Zweckstetter, M.: Conformational flexibility in the transmembrane protein TSPO. Chemistry-A European Journal 21 (46), S. 16555 - 16563 (2015)
  57. Zeitschriftenartikel
    Gapsys, V.; Narayanan, R. L.; Xiang, S.; de Groot, B. L.; Zweckstetter, M.: Improved validation of IDP ensembles by one-bond Cα-Hα scalar couplings. Journal of Biomolecular NMR 63 (3), S. 299 - 307 (2015)
  58. Zeitschriftenartikel
    Kadavath, H.; Jaremko, M.; Jaremko, L.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Folding of the Tau protein on microtubules. Angewandte Chemie International Edition 54 (35), S. 10347 - 10351 (2015)
  59. Zeitschriftenartikel
    Schwalbe, M.; Kadavath, H.; Biernat, J.; Ozenne, V.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of Tau phosphorylation at threonine 231. Structure 23 (8), S. 1448 - 1458 (2015)
  60. Zeitschriftenartikel
    Jaremko, M.; Jaremko, L.; Jaipuria, G.; Becker, S.; Zweckstetter, M.: Structure of the mammalian TSPO/PBR protein. Biochemical Society Transactions 43 (4) (2015)
  61. Zeitschriftenartikel
    Wysoczanski, P.; Becker, S.; Zweckstetter, M.: Structures of intermediates during RES complex assembly. Scientific Reports 5 (2015)
  62. Zeitschriftenartikel
    Fontaine, S. N.; Martin, M. D.; Akoury, E.; Assimon, V. A.; Borysov, S.; Nordhues, B. A.; Sabbagh, J. J.; Cockman, M.; Gestwicki, J. E.; Zweckstetter, M. et al.; Dickey, C. A.: The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics. Human Molecular Genetics 24 (14), S. 3971 - 3981 (2015)
  63. Zeitschriftenartikel
    Jaremko, M.; Jaremko, L.; Giller, K.; Becker, S.; Zweckstetter, M.: Structural integrity of the A147T polymorph of mammalian TSPO. ChemBioChem 16 (10), S. 1483 - 1489 (2015)
  64. Zeitschriftenartikel
    Gut, P.; Zweckstetter, M.; Banati, R. B.: Lost in translocation: The functions of the 18-kD translocator protein. Trends in Endocrinology and Metabolism 26 (7) (2015)
  65. Zeitschriftenartikel
    Kadavath, H.; Hofele, R. V.; Biernat, J.; Kumar, S.; Tepper, K.; Urlaub, H.; Mandelkow, E.; Zweckstetter, M.: Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proceedings of the National Academy of Sciences of the United States of America 112 (24) (2015)
  66. Zeitschriftenartikel
    Kunadt, M.; Eckermann, K.; Stuendl, A.; Gong, J.; Russo, B.; Strauss, K.; Rai, S.; Kügler, S.; Falomir Lockhart, L. J.; Schwalbe, M. et al.; Krumova, P.; Oliveira, L. M. A.; Bähr, M.; Möbius, W.; Levin, J.; Giese, A.; Kruse, N.; Mollenhauer, B.; Geiss-Friedlander, R.; Ludolph, A. C.; Freischmidt, A.; Feiler, M. S.; Danzer, K. M.; Zweckstetter, M.; Jovin, T. M.; Simons, M.; Weishaupt, J. H.; Schneider, A.: Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica 129 (5), S. 695 - 713 (2015)
  67. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Klama, F.; Munari, F.; Zweckstetter, M.: HYCUD: A computational tool for prediction of effective rotational correlation time in flexible proteins. Bioinformatics 31 (8), S. 1319 - 1321 (2015)
  68. Zeitschriftenartikel
    Mbefo, M. K.; Fares, M. B.; Paleologou, K.; Oueslati, A.; Yin, G.; Tenreiro, S.; Pinto, M.; Outeiro, T.; Zweckstetter, M.; Masliah, E. et al.; Lashuel, H. A.: Parkinson disease mutant E46K enhances alpha-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. Journal of Biological Chemistry 290 (15) (2015)
  69. Zeitschriftenartikel
    Gattin, Z.; Schneider, R.; Laukat, Y.; Giller, K.; Maier, E.; Zweckstetter, M.; Griesinger, C.; Benz, R.; Becker, S.; Lange, A.: Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2. Journal of Biomolecular NMR 61 (3-4), S. 311 - 320 (2015)
  70. Zeitschriftenartikel
    Camacho-Zarco, A. R.; Munari, F.; Wegstroth, M.; Liu, W. M.; Ubbink, M.; Becker, S.; Zweckstetter, M.: Multiple paramagnetic effects through a tagged reporter protein. Angewandte Chemie International Edition 54 (1), S. 336 - 339 (2015)
  71. Zeitschriftenartikel
    Miotto, M. C.; Valiente-Gabioud, A. A.; Rossetti, G.; Zweckstetter, M.; Carloni, P.; Selenko, P.; Griesinger, C.; Binolfi, A.; Fernández, C. O.: Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding. Journal of the American Chemical Society 137 (20), S. 6444 - 6447 (2015)
  72. Zeitschriftenartikel
    Fonseca-Ornelas, L.; Eisbach, S. E.; Paulat, M.; Giller, K.; Fernandez, C. O.; Outeiro, T. F.; Becker, S.; Zweckstetter, M.: Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation. Nature Communications 5 (2014)
  73. Zeitschriftenartikel
    Bajaj, R.; Munari, F.; Becker, S.; Zweckstetter, M.: Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes. Journal of Biological Chemistry 289 (50), S. 34620 - 34626 (2014)
  74. Zeitschriftenartikel
    Miotto, M. C.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of Inorganic Biochemistry 141, S. 208 - 211 (2014)
  75. Zeitschriftenartikel
    Yao, X.; Becker, S.; Zweckstetter, M.: A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 60 (4), S. 231 - 240 (2014)
  76. Zeitschriftenartikel
    Parigi, G.; Rezaei-Ghaleh, N.; Giachetti, A.; Becker, S.; Fernandez, C.; Blackledge, M.; Griesinger, C.; Zweckstetter, M.; Luchinat, C.: Long-range correlated dynamics in intrinsically disordered proteins. Journal of the American Chemical Society 136 (46), S. 16201 - 16209 (2014)
  77. Zeitschriftenartikel
    Yao, X.; Dürr, U. H. N.; Gattin, Z.; Laukat, Y.; Narayanan, R.L.; Brückner, A. K.; Meisinger, C.; Lange, A.; Becker, S.; Zweckstetter, M.: NMR-based detection of hydrogen/deuterium exchange in liposome-embedded membrane proteins. PLOS One 9 (11) (2014)
  78. Zeitschriftenartikel
    Bajaj, R.; Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure 22 (10), S. 1501 - 1511 (2014)
  79. Zeitschriftenartikel
    Wysoczanski, P.; Schneider, C.; Xiang, S. Q.; Munari, F.; Trowitzsch, S.; Wahl, M. C.; Lührmann, R.; Becker, S.; Zweckstetter, M.: Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 21 (10), S. 911 - 918 (2014)
  80. Zeitschriftenartikel
    Yin, G.; Lopes da Fonseca, T.; Eisbach, S. E.; Anduaga, A. M.; Breda, C.; Orcellet, M. L.; Szegő, E. M.; Guerreiro, P.; Lázaro, D. F.; Braus, G. H. et al.; Fernandez, C. O.; Griesinger, C.; Becker, S.; Goody, R. S.; Itzen, A.; Giorgini, F.; Outeiro, T. F.; Zweckstetter, M.: α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease 70, S. 149 - 161 (2014)
  81. Zeitschriftenartikel
    Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Toward the functional oligomerization state of tryptophan-rich sensory proteins. Protein Science 23 (8), S. 1154 - 1160 (2014)
  82. Zeitschriftenartikel
    Jensen, M. R.; Zweckstetter, M.; Huang, J.; Blackledge, M.: Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chemical Reviews 114 (13), S. 6632 - 6660 (2014)
  83. Zeitschriftenartikel
    Xiang, S. Q.; Zweckstetter, M.: Detection of a transient intramolecular hydrogen bond using (l)J(NH) scalar couplings. Journal of Magnetic Resonance 243, S. 93 - 97 (2014)
  84. Zeitschriftenartikel
    Villinger, S.; Giller, K.; Bayrhuber, M.; Lange, A.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Nucleotide interactions of the human voltage-dependent anion channel. Journal of Biological Chemistry 289 (19), S. 13397 - 13406 (2014)
  85. Zeitschriftenartikel
    Miotto, M. C.; Rodriguez, E. E.; Valiente-Gabioud, A. A.; Torres-Monserrat, V.; Binolfi, A.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific copper-catalyzed oxidation of alpha-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease. Inorganic Chemistry 53 (9), S. 4350 - 4358 (2014)
  86. Zeitschriftenartikel
    Munari, F.; Gajda, M. J.; Hiragami-Hamada, K.; Fischle, W.; Zweckstetter, M.: Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1 beta. FEBS Letters 588 (7), S. 1094 - 1099 (2014)
  87. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Amininasab, M.; Giller, K.; Kumar, S.; Stuendl, A.; Schneider, A.; Becker, S.; Walter, J.; Zweckstetter, M.: Turn plasticity distinguishes different modes of amyloid-beta aggregation. Journal of the American Chemical Society 136 (13), S. 4913 - 4919 (2014)
  88. Zeitschriftenartikel
    Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S.; Zweckstetter, M.: Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 343 (6177), S. 1363 - 1366 (2014)
  89. Zeitschriftenartikel
    Karagoz, G. E.; Duarte, A. M. S.; Akoury, E.; Ippel, H.; Biernat, J.; Luengo, T. M.; Radli, M.; Didenko, T.; Nordhues, B. A.; Veprintsev, D. B. et al.; Dickey, C. A.; Mandelkow, E.; Zweckstetter, M.; Boelens, R.; Madl, T.; Rudiger, S. G. D.: Hsp90-Tau complex reveals molecular basis for specificity in chaperone action. Cell 156 (5), S. 963 - 974 (2014)
  90. Zeitschriftenartikel
    Schwalbe, M.; Ozenne, V.; Bibow, S.; Jaremko, M.; Jaremko, L.; Gajda, M. J.; Jensen, M. R.; Biernat, J.; Becker, S.; Mandelkow, E. et al.; Zweckstetter, M.; Blackledge, M.: Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 22 (2), S. 238 - 249 (2014)
  91. Zeitschriftenartikel
    Buhl, T.; Braun, A.; Forkel, S.; Moebius, W.; van Werven, L.; Jahn, O.; Rezaei-Ghaleh, N.; Zweckstetter, M.; Mempel, M.; Schoen, M. P. et al.; Haennssle, H. A.: Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Experimental Dermatology 23 (1), S. 20 - 26 (2014)
  92. Zeitschriftenartikel
    Schwalbe, M.; Biernat, J.; Bibow, S.; Ozenne, V.; Jensen, M. R.; Kadavath, H.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2. Biochemistry 52 (50), S. 9068 - 9079 (2013)
  93. Zeitschriftenartikel
    Xiang, S. Q.; Gapsys, V.; Kim, H. Y.; Bessonov, S.; Hsiao, H. H.; Möhlmann, S.; Klaukien, V.; Ficner, R.; Becker, S.; Urlaub, H. et al.; Lührmann, R.; de Groot, B.; Zweckstetter, M.: Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 21 (12), S. 2162 - 2174 (2013)
  94. Zeitschriftenartikel
    Rezaei-Ghaleh, N.; Klama, F.; Munari, F.; Zweckstetter, M.: Predicting the rotational tumbling of dynamic multidomain proteins and supramolecular complexes. Angewandte Chemie International Edition 52 (43), S. 11410 - 11414 (2013)
  95. Zeitschriftenartikel
    Taschenberger, G.; Toloe, J.; Tereshchenko, J.; Akerboom, J.; Wales, P.; Benz, R.; Becker, S.; Outeiro, T. F.; Looger, L. L.; Bähr, M. et al.; Zweckstetter, M.; Kügler, S.: Beta-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology 74 (1) (2013)
  96. Zeitschriftenartikel
    Bouter, I.; Dittrich, K.; Wittnam, J. L.; Rezaei-Ghaleh, N.; Pillot, T.; Papot-Coutourier, S.; Lefebvre, T.; Sprenger, F.; Wirths, O.; Zweckstetter, M. et al.; Bayer, T. A.: N-truncated amyloid beta (A beta) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathologica 126 (2), S. 189 - 205 (2013)
  97. Zeitschriftenartikel
    Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6) (2013)
  98. Zeitschriftenartikel
    Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), S. 795 - 813 (2013)
  99. Zeitschriftenartikel
    Zweckstetter, M.: Conserved amyloid core structure of stop mutants of the human prion protein. Prion 7 (3), S. 193 - 197 (2013)
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