Department of Molecular Biology Seminar Series: Epigenetic Regulation of Tumor Cell Plasticity and Therapeutic Responsiveness
Apr 26, 2018
13:00 - 14:00
University Medical Center Göttingen
Max-Planck-Institut für biophysikalische Chemie (MPIBPC)
Tower IV, Seminar Room, 2nd Floor
Prof. Dr. Patrick Cramer
Tumor cells utilize a very diverse array of mechanisms to proliferate uncontrolled, evade therapy and metastasize. Irrespective of the underlying cause of a tumor, essentially all tumor-specific changes ultimately converge in the altered expression of genes in the cell. The goal of our work is to understand the epigenetic and transcriptional regulatory processes by which tumor-specific changes in gene activity lead to tumorigenesis and tumor progression. More importantly, we aim to utilize this information to identify better and more efficient therapies for various gastrointestinal tumors.