The contribution of medically assisted reproduction to an understanding of human gamete and early embryo function: Cell and Developmental Biology Seminar Series

The contribution of medically assisted reproduction to an understanding of human gamete and early embryo function

  • Datum: 13.02.2020
  • Uhrzeit: 11:00 - 12:00
  • Vortragende(r): Giovanni Coticchio
  • 9.Baby – Family and Fertility Center, Bologna, Italy
  • Ort: Max-Planck-Institut für biophysikalische Chemie (MPIBPC)
  • Raum: Tower V, 1st floor, seminar room (Melina Schuh lab)
  • Gastgeber: Dr. Melina Schuh
  • Kontakt: tommaso.cavazza@mpibpc.mpg.de
As early as the late 1970’, medically assisted reproduction (MAR) has represented a treatment option for 15-20% of couples worldwide affected by infertility. More recently, MAR has also been proposed to delay motherhood and preserve fertility in subjects at risk of premature loss of gonadal function.
The MAR process involves recovery of gametes and their manipulation in vitro to achieve fertilisation and preimplantation development, followed by embryo replacement into the uterine environment. This has allowed to observe, and sometimes study experimentally, human gamete and embryo behaviour under defined and controlled conditions, with unprecedented detail. Therefore, with MAR our appreciation of gamete function and early human development has increased immensely. This talk will offer examples of MAR applications that have revealed some aspects of gamete and embryo function and response of reproductive cells to manipulation, such as cryopreservation.
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