Department of Molecular Biology Seminar Series: Multi scale changes in genome organization and transcription upon cellular ageing

Department of Molecular Biology Seminar Series

  • Datum: 13.01.2020
  • Uhrzeit: 13:00 - 14:00
  • Vortragende(r): Argyris Papantonis
  • University Medical Center Göttingen
  • Ort: Max-Planck-Institut für biophysikalische Chemie (MPIBPC)
  • Raum: Tower IV, Seminar Room, 2nd Floor
  • Gastgeber: Prof. Dr. Patrick Cramer
  • Kontakt: office.cramer@mpibpc.mpg.de
Department of Molecular Biology Seminar Series: Multi scale changes in genome organization and transcription upon cellular ageing
Chromatin and its folding have gained significant attention over the last decade. Right now, it is widely accepted that the spatial organization of chromatin critically impacts nuclear processes, such as transcription, replication, or DNA repair, as well as the overall physiology of the cell. In this seminar, I will present data from replicative senescence and from a rare premature progeria-like syndrome that exemplify how changes in chromatin organization can act as key switches in cellular homeostasis on the path towards cellular and organismal ageing.
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