A research team headed by Marina Bennati at the MPI for Biophysical Chemistry, together with colleagues at the University of Florence (Italy), has shown that 13C NMR spectroscopy signals can be strongly enhanced in solution by resonant microwave irradiation of a nitroxide organic radical used as polarizer for 13C nuclei. The new method shows up to 1000-fold improvements in sensitivity and promises to study small molecules and metabolites in much greater detail.
more