Transkription

For the first time in 3D and atomic resolution: Researchers at the Max Planck Institute for Biophysical Chemistry, in cooperation with colleagues from Würzburg, have succeeded in presenting the propagation strategy of Vaccinia viruses. These viruses also serve as vaccines against human smallpox diseases and as the basis for new cancer therapies. more

A research team at the MPI for Biophysical Chemistry together with colleagues at Rowan University (USA) has structurally visualized how the accessory factors of the mitochondrial RNA polymerase enable mitochondrial transcription during initiation and elongation. Together with functional data, the structures resulted in a movie of transcription in human mitochondria and demonstrate how this process differs from transcription in the cell nucleus. more

Researchers around Patrick Cramer at the MPI for Biophysical Chemistry have analyzed in detail how an important promoter protein complex is assembled and controls the start of transcription. more