Publications of M. Konrad
All genres
Journal Article (90)
61.
Journal Article
277 (6), pp. 4159 - 4165 (2002)
Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains. Journal of Biological Chemistry 62.
Journal Article
268, pp. 1972 - 1981 (2001)
Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene. European Journal of Biochemistry 63.
Journal Article
183, pp. 4910 - 4913 (2001)
YLR 209 c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase. Journal of Bacteriology 64.
Journal Article
40, pp. 7334 - 7341 (2001)
Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequence. Biochemistry 65.
Journal Article
267, pp. 606 - 615 (2000)
Cloning of the guanylate kinase homologues AGK-1 and AGK-2 from Arabidopsis thaliana and characterization of AGK-1. European Journal of Biochemistry 66.
Journal Article
156, pp. 953 - 961 (2000)
Yeast GMP kinase mutants constitutively express AMP biosynthesis genes by phenocopying a hypoxanthine-guanine phosphoribosyltransferase defect. Genetics 67.
Journal Article
39, pp. 11913 - 11920 (2000)
Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modification. Biochemistry 68.
Journal Article
304, pp. 43 - 53 (2000)
Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. Journal of Molecular Biology 69.
Journal Article
8, pp. 629 - 642 (2000)
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. Structure 70.
Journal Article
274, pp. 35289 - 35292 (1999)
Modifying human thymidylate kinase to potentiate AZT activation. Journal of Biological Chemistry 71.
Journal Article
274, pp. 35337 - 35342 (1999)
Binding of nucleotides to guanylate kinase, p21ras, and nucleoside-diphosphate kinase studied by nano-electrospray mass spectrometry. Journal of Biological Chemistry 72.
Journal Article
274, pp. 20159 - 20164 (1999)
Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation. Journal of Biological Chemistry 73.
Journal Article
252, pp. 305 - 313 (1998)
Functional analysis of the guanylate kinase-like domain in the synapse-associated protein SAP97. European Journal of Biochemistry 74.
Journal Article
37, pp. 3677 - 3686 (1998)
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation. Biochemistry 75.
Journal Article
95, pp. 14045 - 14050 (1998)
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences USA 76.
Journal Article
273, pp. 5662 - 5670 (1998)
Transient kinetic studies on phosphoryl transfer reactions of human nucleoside diphosphate kinase. Journal of Biological Chemistry 77.
Journal Article
3 (8), pp. 922 - 924 (1997)
The bottleneck in AZT activation. Nature Medicine 78.
Journal Article
272 (25), pp. 15599 - 15602 (1997)
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding. Journal of Biological Chemistry 79.
Journal Article
72 (2), p. TH387 - TH387 (1997)
Transient kinetic studies of phosphate-transfer reactions in human-beta nucleoside diphosphate kinase. Biophysical Journal 80.
Journal Article
4, pp. 601 - 604 (1997)
Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature Structural Biology