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Journal Article (27)
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1.Journal ArticleMultiple RNA-RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome. Nucleic Acids Research 46 (22), pp. 12126 - 12138 (2018)
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2.Journal ArticleStructure and conformational dynamics of the human spliceosomal Bact complex. Cell 172 (3), pp. 454 - 464, e1-e5 (2018)
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3.Journal ArticleYeast Prp2 liberates the 5' splice site and the branch site adenosine for catalysis of pre-mRNA splicing. RNA 23 (12), pp. 1770 - 1779 (2017)
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4.Journal ArticleCryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 542 (7641), pp. 318 - 323 (2017)
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5.Journal ArticleMolecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 353 (6306), pp. 1399 - 1405 (2016)
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6.Journal ArticleDynamic contacts of U2, RES, Cwc25, Prp8 and Prp45 proteins with the Pre-mRNA branch-site and 3' splice site during catalytic activation and step 1 catalysis in yeast spliceosomes. PLoS Genetics 11 (9) (2015)
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7.Journal ArticleRNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core. EMBO Journal 32 (21), pp. 2804 - 2818 (2013)
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8.Journal ArticleRetention of posttranscriptional spliceosomes in nuclear speckles until splicing completion. Nature communications 3 (2012)
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9.Journal ArticlePhosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nature Structural & Molecular Biology 15 (5), pp. 435 - 443 (2008)
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10.Journal ArticleBinding of the human Prp31 nop domain to a composite RNA-protein platform in U4 snRNP. Science 316, 5821, pp. 115 - 120 (2007)
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11.Journal ArticleComposition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 26 (6), pp. 1737 - 1748 (2007)
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12.Journal ArticleThe 5′ end of U2 snRNA is in close proximity to U1 and functional sites of the Pre-mRNA in early spliceosomal complexes. Molecular Cell 25 (3), pp. 399 - 411 (2007)
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13.Journal ArticleRNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoprotein. Journal of Biological Chemistry 281 (38), pp. 28278 - 28286 (2006)
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14.Journal ArticleProtein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and Cellular Biology 26 (14), pp. 5528 - 5543 (2006)
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15.Journal ArticleProximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes. EMBO Journal 25 (11), pp. 2475 - 2486 (2006)
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16.Journal ArticleU2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Molecular and Cellular Biology 26 (7), pp. 2803 - 2816 (2006)
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17.Journal ArticleFunctional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP. RNA 12, pp. 1738 - 1746 (2006)
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18.Journal ArticleRNA structure and RNA-protein interactions in purified yeast U6 snRNPs. Journal of Molecular Biology 356, pp. 1248 - 1262 (2006)
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19.Journal ArticleModified nucleotides at the 5 ' end of human U2 snRNA are required for spliceosomal E-complex formation. RNA 10 (12), pp. 1925 - 1933 (2004)
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20.Journal ArticleAnalysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry. RNA-A Publication of the RNA Society 9 (12), pp. 1542 - 1551 (2003)