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Journal Article (15)

  1. 1.
    Journal Article
    Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18) (2019)
  2. 2.
    Journal Article
    Draycheva, A.; Bornemann, T.; Ryazanov, S.; Lakomek, N. A.; Wintermeyer, W.: The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), pp. 152 - 167 (2016)
  3. 3.
    Journal Article
    Fasshuber, H. K.; Lakomek, N. A.; Habenstein, B.; Loquet, A.; Shi, C.; Giller, K.; Wolff, S.; Becker, S.; Lange, A.: Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR. Protein Science 24 (5), pp. 592 - 598 (2015)
  4. 4.
    Journal Article
    Lakomek, N. A.; Kaufman, J. D.; Stahl, S. J.; Wingfield, P. T.: HIV-1 envelope protein gp41: An NMR study of dodecyl phosphocholine embedded gp41 reveals a dynamic prefusion intermediate conformation. Structure 22 (9), pp. 1311 - 1321 (2014)
  5. 5.
    Journal Article
    Ban, D.; Funk, M.; Gulich, R.; Egger, D.; Sabo, T. M.; Walter, K. F. A.; Fenwick, R. B.; Giller, K.; Pichierri, F.; de Groot, B. L. et al.; Lange, O. F.; Grubmüller, H.; Salvatella, X.; Wolf, M.; Loidl, A.; Kree, R.; Becker, S.; Lakomek, N. A.; Lee, D.; Lunkenheimer, P.; Griesinger, C.: Kinetics of conformational sampling in ubiquitin. Angewandte Chemie-International Edition 50 (48), pp. 11437 - 11440 (2011)
  6. 6.
    Journal Article
    Fenwick, R. B.; Esteban-Martin, S.; Richter, B.; Lee, D.; Walter, K. F. A.; Milovanovic, D.; Becker, S.; Lakomek, N. A.; Griesinger, C.; Salvatella, X.: Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition. Journal of the American Chemical Society 133 (27), pp. 10336 - 10339 (2011)
  7. 7.
    Journal Article
    Fares, C.; Lakomek, N. A.; Walter, K.; Frank, B. T. C.; Meiler, J.; Becker, S.; Griesinger, C.: Accessing ns-us side-chain dynamics in ubiquitin with methyl RDCs. Journal of Biomolecular NMR 45 (1-2), pp. 23 - 44 (2009)
  8. 8.
    Journal Article
    Friedland, G. D.; Lakomek, N. A.; Griesinger, C.; Meiler, J.; Kortemme, T.: A correspondence between solution-state dynamics of an individual protein and the sequence and conformational divertisy of its family. PLoS Computational Biology, e1000393 (2009)
  9. 9.
    Journal Article
    Salmon, L.; Bouvignies, G.; Marwick, P.; Lakomek, N. A.; Showalter, S.; Li, D. W.; Walter, K.; Griesinger, C.; Brueschweiler, R.; Blackledge, M.: Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angewandte Chemie International Edition 48 (23), pp. 4154 - 4157 (2009)
  10. 10.
    Journal Article
    Lakomek, N. A.; Lange, O.; Walter, K.; Fares, C.; Egger, D.; Lunkenheimer, P.; Meiler, J.; Grubmueller, H.; Becker, S.; de Groot, B. L. et al.; Griesinger, C.: Residual dipolar couplings as a tool to study molecular recognition of ubiquitin. Biochemical Society Transactions 36 (6), pp. 1433 - 1437 (2008)
  11. 11.
    Journal Article
    Lakomek, N. A.; Walter, K.; Fares, C.; Lange, O.; de Groot, B. L.; Grubmueller, H.; Brueschweiler, R.; Munk, A.; Becker, S.; Meiler, J. et al.; Griesinger, C.: Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. Journal of Biomolecular NMR 41 (3), pp. 139 - 155 (2008)
  12. 12.
    Journal Article
    Lange, O.F.; Lakomek, N. A.; Fares, C.; Schroeder, G. F.; Walter, K.; Becker, S.; Meiler, J.; Grubmueller, H.; Griesinger, C.; de Groot, B. L.: Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science 320 (5882), pp. 1471 - 1475 (2008)
  13. 13.
    Journal Article
    Lakomek, N. A.; Carlomagno, T.; Becker, S.; Griesinger, C.; Meiler, J.: A thorough dynamic interpretation of residual dipolar couplings in ubiquitin. Journal of Biomolecular NMR 34 (2), pp. 101 - 115 (2006)
  14. 14.
    Journal Article
    Lakomek, N. A.; Fares, C.; Becker, S.; Carlomagno, T.; Meiler, J.; Griesinger, C.: Side-chain orientation and hydrogen-bonding imprint supra-tau(c) motion on the protein backbone of ubiquitin. Angewandte Chemie-International Edition 44 (47), pp. 7776 - 7778 (2005)
  15. 15.
    Journal Article
    Razeto, A.; Ramakrishnan, V.; Litterst, C. M.; Giller, K.; Griesinger, C.; Carlomagno, T.; Lakomek, N. A.; Heimburg, T.; Lodrini, M.; Pfitzner, E. et al.; Becker, S.: Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain. Journal of Molecular Biology 336 (2), pp. 319 - 329 (2004)

Conference Paper (1)

  1. 16.
    Conference Paper
    Lakomek, N. A.; Kaufmann, J. D.; Stahl, S. J.; Louis, J. M.; Grishaev, A.; Wingfield, P. T.; Bax, A.: The homotrimeric HIV-1 viral coat protein gp41 is highly dynamic. 57th Annual Meeting of the Biophysical-Society, Philadelphia/PA, February 02, 2013 - February 06, 2013. Biophysical Journal 104 (Supplement 1), p. 384A - 384A (2013)

Thesis - PhD (1)

  1. 17.
    Thesis - PhD
    Lakomek, N. A.: New methods in NMR spectroscopy for the study of protein dynamics. Dissertation, XIV, 159 pp., Georg-August-Universität, Göttingen (2009)
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