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Journal Article (17)

  1. 1.
    Journal Article
    Natarajan, N.; Foresti, O.; Wendrich, K.; Stein, A.; Carvalho, P.: Quality control of protein complex assembly by a transmembrane recognition factor. Molecular Cell 77 (1), pp. 108 - 119 (2020)
  2. 2.
    Journal Article
    Schoebel, S.; Mi, W.; Stein, A.; Ovchinnikov, S.; Pavlovicz, R.; DiMaio, F.; Baker, D.; Chambers, M. G.; Su, H.; Li, D. et al.; Rapoport, T. A.; Liao, M.: Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature 548 (7667), pp. 352 - 355 (2017)
  3. 3.
    Journal Article
    Stein, A.; Ruggiano, A.; Carvalho, P.; Rapoport, T. A.: Key steps in ERAD of luminal ER proteins reconstituted with purified components. Cell 158 (6), pp. 1375 - 1388 (2014)
  4. 4.
    Journal Article
    Hernandez, J. M.; Stein, A.; Behrmann, E.; Riedel, D.; Cypionka, A.; Farsi, Z.; Walla, P. J.; Raunser, S.; Jahn, R.: Membrane fusion intermediates via directional and full assembly of the SNARE complex. Science 336 (6088), pp. 1581 - 1584 (2012)
  5. 5.
    Journal Article
    Li, H.; Pink, M. D.; Murphy, J. G.; Stein, A.; Dell'Acqua, M. L.; Hogan, P. G.: Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling. Nature Structural and Molecular Biology 19, pp. 337 - 345 (2012)
  6. 6.
    Journal Article
    Wiederhold, K.; Klöpper, T. H.; Walter, A. M.; Stein, A.; Kienle, N.; Sörensen, J. B.; Fasshauer, D.: A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex. Journal of Biological Chemistry 285 (28), pp. 21549 - 21559 (2010)
  7. 7.
    Journal Article
    Ellena, J. F.; Liang, B. Y.; Wiktor, M.; Stein, A.; Cafiso, D. S.; Jahn, R.; Tamm, L. K.: Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America 106 (48), pp. 20306 - 20311 (2009)
  8. 8.
    Journal Article
    Domanska, M. K.; Kiessling, V.; Stein, A.; Fasshauer, D.; Tamm, L. K.: Single vesicle millisecond fusion kinetics reveals number of SNARE complexes optimal for fast SNARE-mediated membrane fusion. Journal of Biological Chemistry 284 (46), pp. 32158 - 32166 (2009)
  9. 9.
    Journal Article
    Stein, A.; Jahn, R.: Complexins living up to their name — New light on their role in exocytosis. Neuron 64 (3), pp. 295 - 297 (2009)
  10. 10.
    Journal Article
    Cypionka, A.; Stein, A.; Hernandez, M.; Hippchen, H.; Jahn, R.; Walla, P. J.: Discrimination between docking and fusion of liposomes reconstituted with neuronal SNARE-proteins using FCS. Proceedings of the National Academy of Sciences of the United States of America 106 (44), pp. 18575 - 18580 (2009)
  11. 11.
    Journal Article
    Stein, A.; Weber, G.; Wahl, M. C.; Jahn, R.: Helical extension of the neuronal SNARE complex into the membrane. Nature 460 (7254), pp. 525 - 528 (2009)
  12. 12.
    Journal Article
    Radhakrishnan, A.; Stein, A.; Jahn, R.; Fasshauer, D.: The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate. Journal of Biological Chemistry 284, pp. 25749 - 25760 (2009)
  13. 13.
    Journal Article
    Barszczewski, M.; Chua, J.; Stein, A.; Winter, U.; Heintzmann, R.; Zilly, F. E.; Fasshauer, D.; Lang, T.; Jahn, R.: A novel site of action for α -SNAP in the SNARE conformational cycle controlling membrane fusion. Molecular Biology of the Cell 19 (3), pp. 776 - 784 (2008)
  14. 14.
    Journal Article
    Stein, A.; Radhakrishnan, A.; Riedel, D.; Fasshauer, D.; Jahn, R.: Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Nature Structure & Molecular Biology 14 (10), pp. 904 - 911 (2007)
  15. 15.
    Journal Article
    Pobbati, A.; Stein, A.; Fasshauer, D.: N- to C-terminal SNARE complex assembly promotes rapid membrane fusion. Science 313, pp. 673 - 676 (2006)
  16. 16.
    Journal Article
    Sakaba, T.; Stein, A.; Jahn, R.; Neher, E.: Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage. Science 309 (5733), pp. 491 - 494 (2005)
  17. 17.
    Journal Article
    Schuette, C. G.; Hatsuzawa, K.; Margittai, M.; Stein, A.; Riedel, D.; Kuester, P.; Koenig, M.; Seidel, C.; Jahn, R.: Determinants of liposome fusion mediated by synaptic SNARE proteins. Proceedings of the National Academy of Sciences of the United States of America 101 (9), pp. 2858 - 2863 (2004)

Conference Paper (2)

  1. 18.
    Conference Paper
    Holt, M.; Riedel, D.; Schuette, C.; Stein, A.; Jahn, R.: Probing synaptic vesicle fusion with an in vitro system. Journal of General Physiology 130 (1), p. 10a - 10a (2007)
  2. 19.
    Conference Paper
    Stein, A.; Radhakrishnan, A.; Fasshauer, D.: Studies on the molecular mechanism of the acceleration of SNARE-mediated membrane fusion by synaptotagmin 1. FEBS Journal 274 (Suppl. 1), p. 112 - 112 (2007)

Thesis - PhD (1)

  1. 20.
    Thesis - PhD
    Stein, A.: Untersuchungen zur Rekonstitution der SNARE-vermittelten Membranfusion. Dissertation, Freie Universität Berlin, Berlin (2008)
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