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Journal Article (18)

  1. Journal Article
    Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Yu, L.; Roumeliotis, T. I.; Diebold, M.; Dybkov, O.; Sotriffer, C.; Urlaub, H.; Choudhary, J. S. et al.; Mansfeld, J.; Lorenz, S.: Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure (2019)
  2. Journal Article
    Rocha de Moura, T.; Mozaffari-Jovin, S.; Szabo, C. Z. K.; Schmitzova, J.; Dybkov, O.; Cretu, C.; Kachala, M.; Svergun, D.; Urlaub, H.; Lührmann, R. et al.; Pena, V.: Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 69 (6), pp. 979 - 992 (2018)
  3. Journal Article
    Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 172 (3), pp. 454 - 464, e1-e5 (2018)
  4. Journal Article
    Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 170 (4), pp. 701 - 713, e1 - e4 (2017)
  5. Journal Article
    Said, N.; Krupp, F.; Anedchenko, E.; Santos, K. F.; Dybkov, O.; Huang, Y. H.; Lee, C. T.; Loll, B.; Behrmann, E.; Bürger, J. et al.; Mielke, T.; Loerke, J.; Urlaub, H.; Spahn, C. M. T.; Weber, G.; Wahl, M. C.: Structural basis for λN-dependent processive transcription antitermination. Nature Microbiology 2 (7), 17062 (2017)
  6. Journal Article
    Bertram, K.; Agafonov, D. E.; Liu, W.; Dybkov, O.; Will, C. L.; Hartmuth, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 542 (7641), pp. 318 - 323 (2017)
  7. Journal Article
    Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), pp. 307 - 319 (2016)
  8. Journal Article
    Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A.; Kumar, V.; Lee, C. T.; Urlaub, H.; Kastner, B. et al.; Stark, H.; Lührmann, R.: Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 353 (6306), pp. 1399 - 1405 (2016)
  9. Journal Article
    Fourmann, J. B.; Dybkov, O.; Agafonov, D. E.; Tauchert, M. J.; Urlaub, H.; Ficner, R.; Fabrizio, P.; Lührmann, R.: The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction. eLife 5 (2016)
  10. Journal Article
    Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.; Urlaub, H.; Lührmann, R.; Stark, H.: Molecular architecture of the human U4/U6.U5 tri-snRNP. Science 351 (6280), pp. 1416 - 1420 (2016)
  11. Journal Article
    Rasche, N.; Dybkov, O.; Schmitzova, J.; Akyildiz, B.; Fabrizio, P.; Lührmann, R.: Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO Journal 31 (6), pp. 1591 - 1604 (2012)
  12. Journal Article
    Ohrt, T.; Prior, M.; Dannenberg, J.; Odenwälder, P.; Dybkov, O.; Rasche, N.; Schmitzova, J.; Gregor, I.; Fabrizio, P.; Enderlein, J. et al.; Lührmann, R.: Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 18 (6), pp. 1244 - 1256 (2012)
  13. Journal Article
    Schmitzova, J.; Rasche, N.; Dybkov, O.; Kramer, K.; Fabrizio, P.; Urlaub, H.; Lührmann, R.; Pena, V.: Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO Journal 31 (9), pp. 2222 - 2234 (2012)
  14. Journal Article
    Yu, Y.; Maroney, P. A.; Denker, J. A.; Zhang, X. H. F.; Dybkov, O.; Luehrmann, R.; Jankowsky, E.; Chasin, L. A.; Nilsen, T. W.: Dynamic regulation of alternative splicing by silencers that modulate 5´ splice site competition. Cell 135 (7), pp. 1224 - 1236 (2008)
  15. Journal Article
    Kuehn-Hoelsken, E.; Dybkov, O.; Sander, B.; Luehrmann, R.; Urlaub, H.: Improved identification of enriched peptide–RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Research 35 (15), e95 (2007)
  16. Journal Article
    Liu, S.; Li, P.; Dybkov, O.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Carlomagno, T.; Wahl, M. C.: Binding of the human Prp31 nop domain to a composite RNA-protein platform in U4 snRNP. Science 316, 5821, pp. 115 - 120 (2007)
  17. Journal Article
    Dybkov, O.; Will, C. L.; Deckert, J.; Behzadnia, N.; Hartmuth, K.; Luehrmann, R.: U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Molecular and Cellular Biology 26 (7), pp. 2803 - 2816 (2006)
  18. Journal Article
    Spadaccini, R.; Reidt, U.; Dybkov, O.; Will, C. L.; Frank, R.; Stier, G.; Corsini, L.; Wahl, M. C.; Luehrmann, R.; Sattler, M.: Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA 12 (3), pp. 410 - 425 (2006)

Book Chapter (1)

  1. Book Chapter
    Dybkov, O.; Urlaub, H.; Lührmann, R.: Protein-RNA crosslinking in native ribonucleoprotein particles. In: Handbook of RNA biochemistry, Vol. 2, 2. ed. Ed., pp. 1029 - 1053 (Eds. Hartmann, R. K.; Bindereif, A.; Schön, A.; Westhof, E.). Wiley-VCH, Weinheim (2013)
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