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Journal Article (26)

  1. Journal Article
    Wegrzynowicz, M.; Bar-On, D.; Calo’, L.; Anichtchik, O.; Iovino, M.; Xia, J.; Ryazanov, S.; Leonov, A.; Giese, A.; Dalley, J. W. et al.; Griesinger, C.; Ashery, U.; Spillantini, M. G.: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica (2019)
  2. Journal Article
    Gong, J.; Szego, E. M.; Leonov, A.; Benito, E.; Becker, S.; Fischer, A.; Zweckstetter, M.; Outeiro, T.; Schneider, A.: Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 39 (19), pp. 3752 - 3769 (2019)
  3. Journal Article
    Heras‐Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy. Movement Disorders 34 (2), pp. 255 - 263 (2019)
  4. Journal Article
    Jaipuria, G.; Giller, K.; Leonov, A.; Becker, S.; Zweckstetter, M.: Insights into cholesterol/membrane protein interactions using paramagnetic solid-state NMR. Chemistry - A European Journal 24 (66), pp. 17606 - 17611 (2018)
  5. Journal Article
    Reiner, A. M.; Schmidt, F.; Ryazanov, S.; Leonov, A.; Weckbecker, D.; Deeg, A. A.; Griesinger, C.; Giese, A.; Zinth, W.: Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (4), pp. 800 - 807 (2018)
  6. Journal Article
    Martinez Hernandez, A.; Urbanke, H.; Gillman, A. L.; Lee, J.; Ryazanov, S.; Agbemenyah, H. Y.; Benito, E.; Jain, G.; Kaurani, L.; Grigorian, G. et al.; Leonov, A.; Rezaei-Ghaleh, N.; Wilken, P.; Arce, F. T.; Wagner, J.; Fuhrman, M.; Caruana, M.; Camilleri, A.; Vassallo, N.; Zweckstetter, M.; Benz, R.; Giese, A.; Schneider, A.; Korte, M.; Lal, R.; Griesinger, C.; Eichele, G.; Fischer, A.: The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine 10 (1) (2018)
  7. Journal Article
    Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J. et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25) (2017)
  8. Journal Article
    Jaipuria, G.; Leonov, A.; Giller, K.; Vasa, S. K.; Jaremko, Ł.; Jaremko, M.; Linser, R.; Becker, S.; Zweckstetter, M.: Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure. Nature Communications 8 (2017)
  9. Journal Article
    Fellner, L.; Kuzdas-Wood, D.; Levin, J.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b partly ameliorates motor deficits despite failure of neuroprotection in a model of advanced multiple system atrophy. Frontiers in Neuroscience 10 (2016)
  10. Journal Article
    Wagner, J.; Krauss, S.; Shi, S.; Ryazanov, S.; Steffen, J.; Miklitz, C.; Leonov, A.; Kleinknecht, A.; Göricke, B.; Weishaupt, J. H. et al.; Weckbecker, D.; Reiner, A. M.; Zinth, W.; Levin, J.; Ehninger, D.; Remy, S.; Kretzschmar, H. A.; Griesinger, C.; Giese, A.; Fuhrmann, M.: Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathologica 130 (5), pp. 619 - 631 (2015)
  11. Journal Article
    Deeg, A. A.; Reiner, A. M.; Schmidt, F.; Schueder, F.; Ryazanov, S.; Ruf, V. C.; Giller, K.; Becker, S.; Leonov, A.; Griesinger, C. et al.; Giese, A.; Zinth, W.: Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates. Biochimica et Biophysica Acta-General Subjects 1850 (9), pp. 1884 - 1890 (2015)
  12. Journal Article
    Shi, S.; Wagner, J.; Mitteregger-Kretzschmar, G.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: Quantitative real-time quaking-induced conversion allows monitoring of disease-modifying therapy in the urine of prion-infected mice. Journal of Neuropathology and Experimental Neurology 74 (9), pp. 924 - 933 (2015)
  13. Journal Article
    Levin, J.; Schmidt, F.; Boehm, C.; Prix, C.; Bötzel, K.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset. Acta Neuropathologica 127 (5), pp. 779 - 780 (2014)
  14. Journal Article
    Schützenmeister, N.; Müller , M.; Reinscheid, U. M.; Griesinger, C.; Leonov, A.: Trapped in misbelief for almost 40 years: Selective synthesis of the four stereoisomers of mefloquine. Chemistry 19 (51), pp. 17584 - 17588 (2013)
  15. Journal Article
    Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), pp. 795 - 813 (2013)
  16. Journal Article
    Müller , M.; Orben, C. M.; Schützenmeister, N.; Schmidt, M.; Leonov, A.; Reinscheid, U. M.; Dittrich, B.; Griesinger, C.: The absolute configuration of (+)- and (-)-erythro-mefloquine. Angewandte Chemie International Edition 52 (23), pp. 6047 - 6049 (2013)
  17. Journal Article
    Schmidt, M.; Sun, H.; Leonov, A.; Griesinger, C.; Reinscheid, U. M.: Chiral discrimination of amines by anisotropic NMR parameters using chiral polyacrylamide-based gels. Magnetic Resonance in Chemistry 50 (Supplement 1), pp. S38 - S44 (2012)
  18. Journal Article
    Peters, F.; Maestre-Martinez, M.; Leonov, A.; Kovacic, L.; Becker, S.; Boelens, R.; Griesinger, C.: Cys-Ph-TAHA: A lanthanide binding tag for RDC and PCS enhanced protein NMR. Journal of Biomolecular NMR 51 (3), pp. 329 - 337 (2011)
  19. Journal Article
    Erdelyi, M.; d'Auvergne, E.; Navarro-Vazquez, A.; Leonov, A.; Griesinger, C.: Dynamics of the glycosidic bond: Conformational space of lactose. Chemistry: A European Journal 17 (34), pp. 9368 - 9376 (2011)
  20. Journal Article
    Krahn, A.; Lottmann, P.; Marquardsen, T.; Tavernier, A.; Tuerke, M. T.; Reese, M.; Leonov, A.; Bennati, M.; Hoefer, P.; Engelke, F. et al.; Griesinger, C.: Shuttle DNP spectrometer with a two-center magnet. Physical Chemistry Chemical Physics 12 (22), pp. 5830 - 5840 (2010)
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