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Journal Article (79)

  1. Journal Article
    Shema-Yaacoby, E.; Nikolov, M.; Haj-Yahya, M.; Siman, P.; Allemand, E.; Yamaguchi, Y.; Muchardt, C.; Urlaub, H.; Brik, A.; Oren, M. et al.; Fischle, W.: Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Reports 4 (3), pp. 601 - 608 (2013)
  2. Journal Article
    Sun, X. J.; Wang, Z. X.; Jiang, Y.; Kost, N.; Soong, T. D.; Chen, W. Y.; Tang, Z. Y.; Nakadai, T.; Elemento, O.; Fischle, W. et al.; Melnick, A.; Patel, D.; Nimer, S. D.; Röder, R. G.: A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature 500 (7460), pp. 93 - 97 (2013)
  3. Journal Article
    Siman, P.; Karthikeyan, S. V.; Nikolov, M.; Fischle, W.; Brik, A.: Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. Angewandte Chemie-International Edition 52 (31), pp. 8059 - 8063 (2013)
  4. Journal Article
    Munari, F.; Rezaei-Ghaleh, N.; Xiang, S. Q.; Fischle, W.; Zweckstetter, M.: Structural plasticity in human heterochromatin protein 1 beta. PLoS One 8 (4) (2013)
  5. Journal Article
    Nikolov, M.; Fischle, W.: Systematic analysis of histone modification readout. Molecular biosystems 9 (2), pp. 182 - 194 (2013)
  6. Journal Article
    Fischle, W.: One, two, three: how histone methylation is read. Epigenomics 4 (6), pp. 641 - 653 (2012)
  7. Journal Article
    Munari, F.; Soeroes, S.; Zenn, H. M.; Schomburg, A.; Kost, N.; Schröder, S.; Klingberg, R.; Rezaei-Ghaleh, N.; Stützer, A.; Gelato, K. A. et al.; Walla, P. J.; Becker, S.; Schwarzer, D.; Zimmermann, B.; Fischle, W.; Zweckstetter, M.: Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287 (40), pp. 33756 - 33765 (2012)
  8. Journal Article
    Liokatis, S.; Stützer, A.; Elsässer, S. J.; Theillet, F. X.; Klingberg, R.; van Rossum, B.; Schwarzer, D.; Allis, C. D.; Fischle, W.; Selenko, P.: Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events. Nature Structural and Molecular Biology 19 (8), pp. 819 - 823 (2012)
  9. Journal Article
    Honda, S.; Lewis, Z.A.; Shimada, K.; Fischle, W.; Sack, R.; Selker, E.U.: Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation. Nature Structural and Molecular Biology 19 (5), pp. 471 - 477 (2012)
  10. Journal Article
    Seeliger, D.; Soeroes, S.; Klingberg, R.; Schwarzer, D.; Grubmüller, H.; Fischle, W.: Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches. ACS Chemical Biology 7 (1), pp. 150 - 154 (2012)
  11. Journal Article
    van Rossum, B.; Fischle, W.; Selenko, P.: Asymmetrically modified nucleosomes expand the histone code. Nature Structural and Molecular Biology 19, pp. 1064 - 1066 (2012)
  12. Journal Article
    Nikolov, M.; Stützer, A.; Mosch, K.; Krasauskas, A.; Soeroes, S.; Stark, H.; Urlaub, H.; Fischle, W.: Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Molecular and Cellular Proteomics 10 (11), pp. 10.1074/mcp.M110.005371-1 - 10.1074/mcp.M110.005371–16 (2011)
  13. Journal Article
    Stojic, L.; Jasencakova, Z.; Prezioso, C.; Stützer, A.; Bodega, B.; Pasini, D.; Klingberg, R.; Mozzetta, C.; Margueron, R.; Puri, P. L. et al.; Schwarzer, D.; Helin, K.; Fischle, W.; Orlando, V.: Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells. Epigenetics and Chromatin 4 (2011)
  14. Journal Article
    Oppikofer, M.; Kueng, S.; Martino, F.; Soeroes, S.; Hancock, S. M.; Chin, J. W.; Fischle, W.; Gasser, S. M.: A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. EMBO Journal 30 (13), pp. 2610 - 2621 (2011)
  15. Journal Article
    Schmitges, F. W.; Prusty, A. B.; Faty, M.; Stützer, A.; Lingaraju, G. M.; Aiwazian, J.; Sack, R.; Hess, D.; Li, L.; Zhou, S. et al.; Bunker, R. D.; Wirth, U.; Bouwmeester, T.; Bauer, A.; Ly-Hartig, N.; Zhao, K.; Chan, H.; Gu, J.; Gut, H.; Fischle, W.; Mueller, J.; Thomae, N. H.: Histone methylation by PRC2 is inhibited by active chromatin marks. Molecular Cell 42 (3), pp. 330 - 341 (2011)
  16. Journal Article
    Jeltsch, A.; Fischle, W.: Molecular epigenetics: Connecting human biology and disease with little marks. ChemBioChem: A European Journal of Chemical Biology 12 (2), pp. 183 - 184 (2011)
  17. Journal Article
    Mosch, K.; Franz, H.; Sörös, S.; Singh, P. B.; Fischle, W.: HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats. Plos One 6 (1) (2011)
  18. Journal Article
    Köster-Eiserfunke, N.; Fischle, W.: H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development. PLoS Genetics 7, e1002017 (2011)
  19. Journal Article
    Tsai, W. W.; Wang, Z.; Yiu, T. T.; Akdemir, K. C.; Xia, W.; Winter, S.; Tsai, C. Y.; Shi, X.; Schwarzer, D.; Plunkett, W. et al.; Aronow, B.; Gozani, O.; Fischle, W.; Hung, M. C.; Patel, D. J.; Barton, M. C.: TRIM24 links a non-canonical histone signature to breast cancer. Nature (London) 468 (7326), pp. 927 - 932 (2010)
  20. Journal Article
    Zhang, Y.; Jurkowska, R.; Sörös, S.; Rajavelu, A.; Dhayalan, A.; Bock, I.; Rathert, P.; Brandt, O.; Reinhardt, R.; Fischle, W. et al.; Jeltsch, A.: Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Research 38 (13), pp. 4246 - 4253 (2010)
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