Zeitschriftenartikel (88)

  1. Zeitschriftenartikel
    Marchenko, I.; Yashchenok, A.; Borodina, T.; Bukreeva, T.; Konrad, M.; Möhwald, H.; Skirtach, A.: Controlled enzyme-catalyzed degradation of polymeric capsules templated on CaCO3: Influence of the number of LbL layers, conditions of degradation, and disassembly of multicompartments. Journal of Controlled Release 162 (3), S. 599 - 605 (2012)
  2. Zeitschriftenartikel
    Nomme, J.; Su, Y.; Konrad, M.; Lavie, A.: Structures of apo and product-bound human L-asparaginase: Insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry 51 (34), S. 6816 - 6826 (2012)
  3. Zeitschriftenartikel
    Gruber, J.; See Too, W. C.; Wong, M. T.; Lavie, A.; McSorley, T.; Konrad, M.: Balance of human choline kinase isoforms is critical for cell cycle regulation: Implications for the development of choline kinase-targeted cancer therapy. FEBS Journal 279 (11), S. 1915 - 1928 (2012)
  4. Zeitschriftenartikel
    Gomez-Perez, V.; McSorley, T.; See Too, W. C.; Konrad, M.; Campos, J. M.: Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line. ChemMedChem 7 (4), S. 663 - 669 (2012)
  5. Zeitschriftenartikel
    Hazra, S.; Szewczak, A.; Ort, S.; Konrad, M.; Lavie, A.: Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry 50 (14), S. 2870 - 2880 (2011)
  6. Zeitschriftenartikel
    Yashchenok, A. M.; Delcea, M.; Videnova, K.; Jares-Erijman, E. A.; Jovin, T. M.; Konrad, M.; Moehwald, H.; Skirtach, A. G.: Enzyme reaction in the pores of CaCO3 particles upon ultrasound disruption of attached substrate-filled liposomes. Angewandte Chemie International Edition 49 (44), S. 8116 - 8120 (2010)
  7. Zeitschriftenartikel
    Yashchenok, A. M.; Delcea, M.; Videnova, K.; Jares-Erijman, E. A.; Jovin, T. M.; Konrad, M.; Moehwald, H.; Skirtach, A. G.: Enzymreaktion in den Poren von CaCO3-Partikeln mit angelagerten, mit Substrat gefüllten Liposomen. Angewandte Chemie 122 (44), S. 8293 - 8297 (2010)
  8. Zeitschriftenartikel
    Too, W. C. E.; Wong, M. T.; Few, L. L.; Konrad, M.: Highly specific antibodies for co-detection of human choline kinase α1 and α2 isoforms. PLoS ONE 5 (9), e12999 (2010)
  9. Zeitschriftenartikel
    Hazra, S.; Konrad, M.; Lavie, A.: The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): Implications for the development of dCK-activated acyclic guanine analogues. Journal of Medicinal Chemistry 53 (15), S. 5792 - 5800 (2010)
  10. Zeitschriftenartikel
    Hazra, S.; Ort, S.; Konrad, M.; Lavie, A.: Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues. Biochemistry 49 (31), S. 6784 - 6790 (2010)
  11. Zeitschriftenartikel
    Hazra, S.; Sabini, E.; Ort, S.; Konrad, M.; Lavie, A.: Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase. Biochemistry 48 (6), S. 1256 - 1263 (2009)
  12. Zeitschriftenartikel
    Paarmann, I.; Lye, M. F.; Konrad, M.: Structural requirements for calmodulin binding to membrane-associated guanylate kinase homologs. Protein Science 17 (11), S. 1946 - 1954 (2008)
  13. Zeitschriftenartikel
    Lavie, A.; Su, Y.; Ghassemi, M.; Novak, R. M.; Caffrey, M.; Sekulic, N.; Monnerjahn, C.; Konrad, M.; Cook, J. L.: Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells. Journal of General Virology 89 (7), S. 1672 - 1679 (2008)
  14. Zeitschriftenartikel
    Gauthier, S.; Coulpier, F.; Jourdren, L.; Merle, M.; Beck, S.; Konrad, M.; Daignan-Fornier, B.; Pinson, B.: Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Molecular Microbiology 68 (6), S. 1583 - 1594 (2008)
  15. Zeitschriftenartikel
    Sabini, E.; Hazra, S.; Ort, S.; Konrad, M.; Lavie, A.: Structural basis for substrate promiscuity of dCK. Journal of Molecular Biology 378 (3), S. 607 - 621 (2008)
  16. Zeitschriftenartikel
    McSorley, T.; Ort, S.; Hazra, S.; Lavie, A.; Konrad, M.: Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS Letters 582 (5), S. 720 - 724 (2008)
  17. Zeitschriftenartikel
    Maytum, R.; Hatch, V.; Konrad, M.; Lehmann, W.; Geeves, M. A.: Ultra short yeast tropomyosins show novel myosin regulation. Journal of Biological Chemistry 283 (4), S. 1902 - 1910 (2008)
  18. Zeitschriftenartikel
    Sabini, E.; Hazra, S.; Konrad, M.; Lavie, A.: Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase. Journal of Medicinal Chemistry 51 (14), S. 4219 - 4225 (2008)
  19. Zeitschriftenartikel
    Segura-Pena, D.; Lichter, J.; Trani, M.; Konrad, M.; Lavie, A.; Lutz, S.: Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes. Structure 15 (12), S. 1555 - 1566 (2007)
  20. Zeitschriftenartikel
    Sekulic, N.; Konrad, M.; Lavie, A.: Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation. Journal of Biological Chemistry 282 (30), S. 22112 - 22121 (2007)
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