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Zeitschriftenartikel (88)

41.
Zeitschriftenartikel
Sabini, E.; Hazra, S.; Konrad, M.; Lavie, A.: Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-Nucleosides. Journal of Medicinal Chemistry 50 (13), S. 3004 - 3014 (2007)
42.
Zeitschriftenartikel
Segura-Pena, D.; Lutz, S.; Monnerjahn, C.; Konrad, M.; Lavie, A.: Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. Journal of Molecular Biology 369 (1), S. 129 - 141 (2007)
43.
Zeitschriftenartikel
Sekulic, N.; Dietrich, K.; Paarmann, I.; Ort, S.; Konrad, M.; Lavie, A.: Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1. Journal of Molecular Biology 367 (2), S. 488 - 500 (2007)
44.
Zeitschriftenartikel
Sabini, E.; Hazra, S.; Konrad, M.; Burley, S. K.; Lavie, A.: Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase. Nucleic Acids Research 35, S. 186 - 192 (2007)
45.
Zeitschriftenartikel
Sato, T.; Neschadim, A.; Konrad, M.; Fowler, D. H.; Lavie, A.; Medin, J. A.: Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Molecular Therapy 15 (5), S. 962 - 970 (2007)
46.
Zeitschriftenartikel
Malito, E.; Sekulic, N.; Too, W. C. S.; Konrad, M.; Lavie, A.: Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine. Journal of Molecular Biology 364 (2), S. 136 - 151 (2006)
47.
Zeitschriftenartikel
Godsey, M. H.; Ort, S.; Sabini, E.; Konrad, M.; Lavie, A.: Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: Illuminating the role of main-chain reorganization. Biochemistry 45 (2), S. 452 - 461 (2006)
48.
Zeitschriftenartikel
Woehrl, B. M.; Loubiere, L.; Brundiers, R.; Goody, R. S.; Klatzmann, D.; Konrad, M.: Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition. Journal of General Virology 86, S. 757 - 764 (2005)
49.
Zeitschriftenartikel
Segura-Pena, D.; Sekulic, N.; Ort, S.; Konrad, M.; Lavie, A.: Substrate-induced conformational changes in human UMP/CMP kinase. Journal of Biological Chemistry 279 (32), S. 33882 - 33889 (2004)
50.
Zeitschriftenartikel
Lavie, A.; Konrad, M.: Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase. Mini-Reviews in Medicinal Chemistry 4 (4), S. 351 - 359 (2004)
51.
Zeitschriftenartikel
Maytum, R.; Bathe, F.; Konrad, M.; Geeves, M. A.: Tropomyosin exon 6b is troponin-specific and required for correct acto-myosin regulation. Journal of Biological Chemistry 279 (18), S. 18203 - 18209 (2004)
52.
Zeitschriftenartikel
Wichmann, C.; Naumann, P. T.; Spangenberg, O.; Konrad, M.; Mayer, F.; Hoppert, M.: Liposomes for microcompartmentation of enzymes and their influence on catalytic activity. Biochemical and Biophysical Research Communications 310 (4), S. 1104 - 1110 (2003)
53.
Zeitschriftenartikel
Gardberg, A.; Shuvalova, L.; Monnerjahn, C.; Konrad, M.; Lavie, A.: Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure 11 (10), S. 1265 - 1277 (2003)
54.
Zeitschriftenartikel
Sabini, E.; Ort, S.; Monnerjahn, C.; Konrad, M.; Lavie, A.: Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nature Structural Biology 10 (7), S. 513 - 519 (2003)
55.
Zeitschriftenartikel
Ostermann, N.; Segura-Pena, D.; Meier, C.; Veit, T.; Monnerjahn, C.; Konrad, M.; Lavie, A.: Structures of human thymidylate kinase in complex with prodrugs: Implications for the structure-based design of novel compounds. Biochemistry 42 (9), S. 2568 - 2577 (2003)
56.
Zeitschriftenartikel
Monnerjahn, C.; Konrad, M.: Modulated nucleoside kinases as tools to improve the activation of therapeutic nucleoside analogues. ChemBioChem 4 (2-3), S. 143 - 146 (2003)
57.
Zeitschriftenartikel
Paarmann, I.; Spangenberg, O.; Lavie, A.; Konrad, M.: Formation of complexes between Ca2+center dot calmodulin and the synapse-associated protein SAP97 requires the SH3 domain- guanylate kinase domain-connecting HOOK region. Journal of Biological Chemistry 277 (43), S. 40832 - 40838 (2002)
58.
Zeitschriftenartikel
Sekulic, N.; Shuvalova, L.; Spangenberg, O.; Konrad, M.; Lavie, A.: Structural characterization of the closed conformation of mouse guanylate kinase. Journal of Biological Chemistry 277 (33), S. 30236 - 30243 (2002)
59.
Zeitschriftenartikel
Li, Y.; Spangenberg, O.; Paarmann, I.; Konrad, M.; Lavie, A.: Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains. Journal of Biological Chemistry 277 (6), S. 4159 - 4165 (2002)
60.
Zeitschriftenartikel
Erent, M.; Gonin, P.; Cherfils, J.; Tissier, P.; Raschella, G.; Giartosio, A.; Agou, F.; Sarger, C.; Lacombe, M. L.; Konrad, M. et al.; Lascu, I.: Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene. European Journal of Biochemistry 268, S. 1972 - 1981 (2001)
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