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Zeitschriftenartikel (88)

  1. 61.
    Zeitschriftenartikel
    Lecoq, K.; Belloc, I.; Desgranges, C.; Konrad, M.; Daignan-Fornier, B.: YLR 209 c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase. Journal of Bacteriology 183, S. 4910 - 4913 (2001)
  2. 62.
    Zeitschriftenartikel
    Maytum, R.; Konrad, M.; Lehrer, S. S.; Geeves, M. A.: Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequence. Biochemistry 40, S. 7334 - 7341 (2001)
  3. 63.
    Zeitschriftenartikel
    Kumar, V.; Spangenberg, O.; Konrad, M.: Cloning of the guanylate kinase homologues AGK-1 and AGK-2 from Arabidopsis thaliana and characterization of AGK-1. European Journal of Biochemistry 267, S. 606 - 615 (2000)
  4. 64.
    Zeitschriftenartikel
    Lecoq, K.; Konrad, M.; Daignan-Fornier, B.: Yeast GMP kinase mutants constitutively express AMP biosynthesis genes by phenocopying a hypoxanthine-guanine phosphoribosyltransferase defect. Genetics 156, S. 953 - 961 (2000)
  5. 65.
    Zeitschriftenartikel
    Maytum, R.; Geeves, M. A.; Konrad, M.: Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modification. Biochemistry 39, S. 11913 - 11920 (2000)
  6. 66.
    Zeitschriftenartikel
    Ostermann, N.; Lavie, A.; Padiyar, S.; Brundiers, R.; Veit, T.; Reinstein, J.; Goody, R. S.; Konrad, M.; Schlichting, I.: Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. Journal of Molecular Biology 304, S. 43 - 53 (2000)
  7. 67.
    Zeitschriftenartikel
    Ostermann, N.; Schlichting, I.; Brundiers, R.; Konrad, M.; Reinstein, J.; Veit, T.; Goody, R. S.; Lavie, A.: Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. Structure 8, S. 629 - 642 (2000)
  8. 68.
    Zeitschriftenartikel
    Brundiers, R.; Lavie, A.; Veit, T.; Reinstein, J.; Schlichting, I.; Ostermann, N.; Goody, R. S.; Konrad, M.: Modifying human thymidylate kinase to potentiate AZT activation. Journal of Biological Chemistry 274, S. 35289 - 35292 (1999)
  9. 69.
    Zeitschriftenartikel
    Prinz, H.; Lavie, A.; Scheidig, A. J.; Spangenberg, O.; Konrad, M.: Binding of nucleotides to guanylate kinase, p21ras, and nucleoside-diphosphate kinase studied by nano-electrospray mass spectrometry. Journal of Biological Chemistry 274, S. 35337 - 35342 (1999)
  10. 70.
    Zeitschriftenartikel
    Schaertl, S.; Geeves, M. A.; Konrad, M.: Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation. Journal of Biological Chemistry 274, S. 20159 - 20164 (1999)
  11. 71.
    Zeitschriftenartikel
    Kuhlendahl, S.; Spangenberg, O.; Konrad, M.; Kim, E.; Garner, C. C.: Functional analysis of the guanylate kinase-like domain in the synapse-associated protein SAP97. European Journal of Biochemistry 252, S. 305 - 313 (1998)
  12. 72.
    Zeitschriftenartikel
    Lavie, A.; Konrad, M.; Brundiers, R.; Goody, R. S.; Schlichting, I.; Reinstein, J.: Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation. Biochemistry 37, S. 3677 - 3686 (1998)
  13. 73.
    Zeitschriftenartikel
    Lavie, A.; Ostermann, N.; Brundiers, R.; Goody, R. S.; Reinstein, J.; Konrad, M.; Schlichting, I.: Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences USA 95, S. 14045 - 14050 (1998)
  14. 74.
    Zeitschriftenartikel
    Schaertl, S.; Konrad, M.; Geeves, M. A.: Transient kinetic studies on phosphoryl transfer reactions of human nucleoside diphosphate kinase. Journal of Biological Chemistry 273, S. 5662 - 5670 (1998)
  15. 75.
    Zeitschriftenartikel
    Lavie, A.; Schlichting, I.; Vetter, I. R.; Konrad, M.; Reinstein, J.; Goody, R. S.: The bottleneck in AZT activation. Nature Medicine 3 (8), S. 922 - 924 (1997)
  16. 76.
    Zeitschriftenartikel
    Lascu, I.; Schaertl, S.; Wang, C. Q.; Sarger, C.; Giartosio, A.; Briand, G.; Lacombe, M. L.; Konrad, M.: A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding. Journal of Biological Chemistry 272 (25), S. 15599 - 15602 (1997)
  17. 77.
    Zeitschriftenartikel
    Schaertl, S.; Konrad, M.; Lascu, I.; Geeves, M. A.: Transient kinetic studies of phosphate-transfer reactions in human-beta nucleoside diphosphate kinase. Biophysical Journal 72 (2), S. TH387 - TH387 (1997)
  18. 78.
    Zeitschriftenartikel
    Lavie, A.; Vetter, I. R.; Konrad, M.; Goody, R. S.; Reinstein, J.; Schlichting, I.: Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature Structural Biology 4, S. 601 - 604 (1997)
  19. 79.
    Zeitschriftenartikel
    Giartosio, A.; Erent, M.; Cervoni, L.; Morera, S.; Janin, J.; Konrad, M.; Lascu, I.: Thermal stability of hexameric and tetrameric nucleoside diphosphate kinases - Effect of subunit interaction. Journal of Biological Chemistry 271 (30), S. 17845 - 17851 (1996)
  20. 80.
    Zeitschriftenartikel
    Konrad, M.: Molecular analysis of the essential gene for adenylate kinase from the fission yeast Schizosaccharomyces pombe. Journal of Biological Chemistry 268 (15), S. 11326 - 11334 (1993)
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