Publikationen von Jana Schmitzová

Zeitschriftenartikel (17)

1.
Zeitschriftenartikel
Schmitzová, J.; Cretu, C.; Dienemann, C.; Urlaub, H.; Pena, V.: Structural basis of catalytic activation in human splicing. Nature 617, S. 842 - 850 (2023)
2.
Zeitschriftenartikel
Kabinger, F.; Stiller, C.; Schmitzova, J.; Dienemann, C.; Kokic, G.; Hillen, H. S.; Höbartner, C.; Cramer, P.: Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nature Structural and Molecular Biology 28 (9), S. 740 - 746 (2021)
3.
Zeitschriftenartikel
Jochheim, F. A.; Tegunov, D.; Hillen, H. S.; Schmitzova, J.; Kokic, G.; Dienemann, C.; Cramer, P.: The structure of a dimeric form of SARS-CoV-2 polymerase. Communications Biology 4, 999 (2021)
4.
Zeitschriftenartikel
Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Höbartner, C.; Cramer, P.: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 12, 279 (2021)
5.
Zeitschriftenartikel
Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Höbartner, C.; Cramer, P.: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 12, 279 (2021)
6.
Zeitschriftenartikel
Rocha de Moura, T.; Mozaffari-Jovin, S.; Szabo, C. Z. K.; Schmitzova, J.; Dybkov, O.; Cretu, C.; Kachala, M.; Svergun, D.; Urlaub, H.; Lührmann, R. et al.; Pena, V.: Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 69 (6), S. 979 - 992 (2018)
7.
Zeitschriftenartikel
Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), S. 307 - 319 (2016)
8.
Zeitschriftenartikel
De, I.; Schmitzova, J.; Pena, V.: The organization and contribution of helicases to RNA splicing. Wiley Interdisciplinary Reviews: RNA 7 (2), S. 259 - 274 (2016)
9.
Zeitschriftenartikel
Schneider, C.; Agafonov, D. E.; Schmitzova, J.; Hartmuth, K.; Fabrizio, P.; Lührmann, R.: Dynamic contacts of U2, RES, Cwc25, Prp8 and Prp45 proteins with the Pre-mRNA branch-site and 3' splice site during catalytic activation and step 1 catalysis in yeast spliceosomes. PLoS Genetics 11 (9), e1005539 (2015)
10.
Zeitschriftenartikel
Warkocki, Z.; Schneider, C.; Mozaffari-Jovin, S.; Schmitzova, J.; Höbartner, C.; Fabrizio, P.; Lührmann, R.: The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development 29 (1), S. 94 - 107 (2015)
11.
Zeitschriftenartikel
Ohrt, T.; Odenwälder, P.; Dannenberg, J.; Prior , M.; Warkocki, Z.; Schmitzova, J.; Karaduman, R.; Gregor, I.; Enderlein, J.; Fabrizio, P. et al.; Lührmann, R.: Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA 19 (7), S. 902 - 915 (2013)
12.
Zeitschriftenartikel
Fourmann, J. B.; Schmitzova, J.; Christian, H.; Urlaub, H.; Ficner, R.; Boon, K. L.; Fabrizio, P.; Lührmann, R.: Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes and Development 27 (4), S. 413 - 428 (2013)
13.
Zeitschriftenartikel
Schmitzova, J.; Pena, V.: Emerging views about the molecular structure of the spliceosomal catalytic center. RNA Biology 9 (11), S. 1311 - 1318 (2012)
14.
Zeitschriftenartikel
Rasche, N.; Dybkov, O.; Schmitzova, J.; Akyildiz, B.; Fabrizio, P.; Lührmann, R.: Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO Journal 31 (6), S. 1591 - 1604 (2012)
15.
Zeitschriftenartikel
Ohrt, T.; Prior, M.; Dannenberg, J.; Odenwälder, P.; Dybkov, O.; Rasche, N.; Schmitzova, J.; Gregor, I.; Fabrizio, P.; Enderlein, J. et al.; Lührmann, R.: Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 18 (6), S. 1244 - 1256 (2012)
16.
Zeitschriftenartikel
Schmitzova, J.; Rasche, N.; Dybkov, O.; Kramer, K.; Fabrizio, P.; Urlaub, H.; Lührmann, R.; Pena, V.: Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO Journal 31 (9), S. 2222 - 2234 (2012)
17.
Zeitschriftenartikel
De Antoni, A.; Schmitzova, J.; Trepte, H. H.; Gallwitz, D.; Albert, S.: Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. Journal of Biological Chemistry 277 (43), S. 41023 - 41031 (2002)
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