Suchergebnisse

Zeitschriftenartikel (8)

  1. 1.
    Zeitschriftenartikel
    Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), S. 11801 - 11812 (2008)
  2. 2.
    Zeitschriftenartikel
    Palecek, E.; Ostatna, V.; Masarík, M.; Bertoncini, C. W.; Jovin, T. M.: Changes in interfacial properties of -synuclein preceding its aggregation. The Analyst 133 (1), S. 76 - 84 (2008)
  3. 3.
    Zeitschriftenartikel
    Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), S. 708 - 722 (2007)
  4. 4.
    Zeitschriftenartikel
    Roberti, M. J.; Bertoncini, C. W.; Klement, R.; Jares-Erijman, E. A.; Jovin, T. M.: Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein. Nature Methods 4 (4), S. 345 - 351 (2007)
  5. 5.
    Zeitschriftenartikel
    Binolfi, A.; Rasia, R. M.; Bertoncini, C. W.; Ceolin, M.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement. Journal of the American Chemical Society 128 (30), S. 9893 - 9901 (2006)
  6. 6.
    Zeitschriftenartikel
    Bertoncini, C. W.; Fernandez, C. O.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. Journal of Biological Chemistry 280, S. 30649 - 30652 (2005)
  7. 7.
    Zeitschriftenartikel
    Rasia, R. M.; Bertoncini, C. W.; Marsh, D.; Hoyer, W.; Cherny, D. I.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Structural characterization of copper(II) binding to α-Synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 102, 10.1073/pnas.0407881102, S. 4294 - 4299 (2005)
  8. 8.
    Zeitschriftenartikel
    Bertoncini, C. W.; Jung, Y. S.; Fernandez, C. O.; Hoyer, W.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein. Proceedings of the National Academy of Sciences of the United States of America 102 (5), S. 1430 - 1435 (2005)

Konferenzbeitrag (1)

  1. 9.
    Konferenzbeitrag
    Bertoncini, C. W.; Cherny, D. I.; Fernandez, C. O.; Garfinkel, E.; Griesinger, C.; Hoyer, W.; Jares-Erijman, E. A.; Jovin, T. M.; Marsh, D.; Rasia, R. M. et al.; Roberti, M. J.; Subramaniam, V.; Zweckstetter, M.: 3D structure, ligand binding, autoinhibition, aggregation, and cellular distribution of wild-type, mutant, and labeled alpha-synuclein. Biophysical Journal 88 (1), S. 396A - 396A (2005)

Hochschulschrift - Doktorarbeit (1)

  1. 10.
    Hochschulschrift - Doktorarbeit
    Bertoncini, C. W.: Structure and dynamics of the aggregation mechanism of the Parkinson´s disease-associated protein alpha-syneclein. Dissertation, 229pp S., Georg-August-Unviersität, Göttingen, Germany (2006)
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