Suchergebnisse

Shi, S.; Wagner, J.; Mitteregger-Kretzschmar, G.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: Quantitative real-time quaking-induced conversion allows monitoring of disease-modifying therapy in the urine of prion-infected mice. Journal of Neuropathology and Experimental Neurology 74 (9), S. 924 - 933 (2015)

Levin, J.; Schmidt, F.; Boehm, C.; Prix, C.; Bötzel, K.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset. Acta Neuropathologica 127 (5), S. 779 - 780 (2014)

Schützenmeister, N.; Müller , M.; Reinscheid, U. M.; Griesinger, C.; Leonov, A.: Trapped in misbelief for almost 40 years: Selective synthesis of the four stereoisomers of mefloquine. Chemistry 19 (51), S. 17584 - 17588 (2013)

Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), S. 795 - 813 (2013)

Müller , M.; Orben, C. M.; Schützenmeister, N.; Schmidt, M.; Leonov, A.; Reinscheid, U. M.; Dittrich, B.; Griesinger, C.: The absolute configuration of (+)- and (-)-erythro-mefloquine. Angewandte Chemie International Edition 52 (23), S. 6047 - 6049 (2013)

Schmidt, M.; Sun, H.; Leonov, A.; Griesinger, C.; Reinscheid, U. M.: Chiral discrimination of amines by anisotropic NMR parameters using chiral polyacrylamide-based gels. Magnetic Resonance in Chemistry 50 (Supplement 1), S. S38 - S44 (2012)

Peters, F.; Maestre-Martinez, M.; Leonov, A.; Kovacic, L.; Becker, S.; Boelens, R.; Griesinger, C.: Cys-Ph-TAHA: A lanthanide binding tag for RDC and PCS enhanced protein NMR. Journal of Biomolecular NMR 51 (3), S. 329 - 337 (2011)

Erdelyi, M.; d'Auvergne, E.; Navarro-Vazquez, A.; Leonov, A.; Griesinger, C.: Dynamics of the glycosidic bond: Conformational space of lactose. Chemistry: A European Journal 17 (34), S. 9368 - 9376 (2011)

Krahn, A.; Lottmann, P.; Marquardsen, T.; Tavernier, A.; Tuerke, M. T.; Reese, M.; Leonov, A.; Bennati, M.; Hoefer, P.; Engelke, F. et al.; Griesinger, C.: Shuttle DNP spectrometer with a two-center magnet. Physical Chemistry Chemical Physics 12 (22), S. 5830 - 5840 (2010)

Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), S. 1025 - 1034 (2008)

Schuetz, A.; Junker, J.; Leonov, A.; Lange, O.; Molinski, T. F.; Griesinger, C.: Stereochemistry of sagittamide a from residual dipolar coupling enhanced NMR. Journal of the American Chemical Society 129 (49), S. 15114 - 15115 (2007)

Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2⁺ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), S. 5015 - 5025 (2007)

Rodriguez-Castaneda, F.; Haberz, P.; Leonov, A.; Griesinger, C.: Paramagnetic tagging of diamagnetic proteins for solution NMR. Magnetic Resonance in Chemistry 44 (Sp. Iss. S1), S. S10 - S16 (2006)

Haberz, P.; Rodriguez-Castaneda, F.; Junker, J.; Becker, S.; Leonov, A.; Griesinger, C.: Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution. Organic Letters 8 (7), S. 1275 - 1278 (2006)

Leonov, A.; Voigt, B.; Rodriguez-Castaneda, F.; Sakhaii, P.; Griesinger, C.: Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine. Chemistry-A European Journal 11 (11), S. 3342 - 3348 (2005)

Buss, S.; Kuebler, L.; Maurer, A.; Schmidt, F.; Leonov, A.; Ryazanov, S.; Giese, A.; Griesinger, C.; Pichler, B. J.; Herfert, K.: In vitro evaluation of small molecule compounds as potential PET tracers targeting a-synuclein. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN and BRAIN Pet), Yokohama, Japan, 04. Juli 2019 - 07. Juli 2019. Journal of Cerebral Blood Flow and Metabolism 39 (Suppl), S. 530 - 531 (2019)

Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K.; Becker, S.; Benz, R.; Eichele, G.; Fischer, A. et al.; Giese, A.; Andreas, L.; Griesinger, C.: Protein-drug interactions in the membrane: The small molecule Anle138b and its binding to alpha-synuclein oligomers. 63rd Annual Meeting of the Biophysical-Society, Baltimore, MD, 02. März 2019 - 06. März 2019. Biophysical Journal 116 (Suppl_1), S. 352A - 352A (2019)

Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K.; Becker, S.; Lee , J.; Lal , R.; Eichele, G. et al.; Fischer , A.; Giese, A.; Andreas, L.; Griesinger, C.: The small molecule anle138b shows interaction with alpha-synuclein oligomers in phospholipid membranes. 62nd Annual Meeting of the Biophysical-Society, San Francisco, CA, 17. Februar 2018 - 21. Februar 2018. Biophysical Journal (Suppl), 3 Aufl., S. 560a - 560a (2018)

Sadasivam, S. M.; Ryazanov, S.; Leonov, A.; Roeters, S.; Wouterson, S.; Giese, A.; Griesinger, C.; Killian, J. A.: Effect of the novel amyloid inhibitor "anle145c" on aggregation of islet amyloid polypeptide and how it is modulated by membranes. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27. Februar 2016 - 02. März 2016. Biophysical Journal 110 (Suppl 1), 3 Aufl., S. 420A - 420A (2016)

Prix, C.; Schmidt, F.; Levin, J.; Schinke, K.; Shi, S.; Ryazanov, S.; Leonov, A.; Högen, T.; Mitteregger-Kretzschmar, G.; Kretzschmar, H. A. et al.; Bötzel, K.; Griesinger, C.; Giese, A.: The oligomer modulator anle138b is effective in the prodromal phase of a transgenic mouse model of Parkinson's disease. Joint Congress of European Neurology, Istanbul, Turkey, 31. Mai 2014 - 03. Juni 2014. European Journal of Neurology 21 (Suppl. 1), S. 170 - 170 (2014)