Suchergebnisse

Warias, M.; Grubmüller, H.; Bock, L. V.: tRNA dissociation from EF-Tu after GTP hydrolysis: Primary steps and antibiotic inhibition. Biophysical Journal 118 (1), S. 151 - 161 (2020)

Peng, B. Z.; Bock, L. V.; Belardinelli, R.; Peske, F.; Grubmüller, H.; Rodnina, M. V.: Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 5 (12), eaax8030 (2019)

Bock, L. V.; Caliskan, N.; Korniy, N.; Peske, F.; Rodnina, M. V.; Grubmüller, H.: Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10, 4598 (2019)

Igaev, M.; Kutzner, C.; Bock, L. V.; Vaiana, A. C.; Grubmüller, H.: Automated cryo-EM structure refinement using correlation-driven molecular dynamics. eLife 8, e43542 (2019)

Bock, L. V.; Kolar, M. H.; Grubmüller, H.: Molecular simulations of the ribosome and associated translation factors. Current Opinion in Structural Biology 49, S. 27 - 35 (2018)

Bock, L. V.; Kolář, M. H.; Grubmüller, H.: Molecular simulations of the ribosome and associated translation factors. arXiv, arXiv:1711.06067 (2017)

Huter, P.; Arenz, S.; Bock, L. V.; Graf, M.; Frister, J. O.; Heuer, A.; Peil, L.; Starosta, A. L.; Wohlgemuth, I.; Peske, F. et al.; Nováček, J.; Berninghausen, O.; Grubmüller, H.; Tenson, T.; Beckmann, R.; Rodnina, M. V.; Vaiana, A. C.; Wilson, D. N.: Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 68 (3), S. 515 - 527 (2017)

Arenz, S.; Bock, L. V.; Graf, M.; Innis, C. A.; Beckmann, R.; Grubmüller, H.; Vaiana, A. C.; Wilson, D. N.: A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. Nature Communications 7, 12026 (2016)

Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation. Nucleic Acids Research 43 (14), S. 6747 - 6760 (2015)

Fischer, N.; Neumann, P.; Konevega, A. L.; Bock, L. V.; Ficner, R.; Rodnina, M. V.; Stark, H.: Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 520 (7548), S. 567 - 570 (2015)

Bock, L. V.; Blau, C.; Schröder, G. F.; Davydov, I. I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), S. 1390 - 1396 (2013)

Bock, L. V.; Kolar, M. H.; Vaiana, A. C.; Russek, A.; von Ardenne, B.; Grubmüller, H.: Molecular basis for the extra-mitochondrial roles of cytochrome c in cell Life and death. Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, 20. Juli 2019 - 24. Juli 2019. European Biophysics Journal 48 (Suppl 1), S. S52 - S52 (2019)

Igaev, M.; Kutzner, C.; Bock, L. V.; Vaiana, A. C.; Grubmüller, H.: Automated cryo-EM structure refinement using correlation -driven molecular dynamics. Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, 20. Juli 2019 - 24. Juli 2019. European Biophysics Journal 48 (Suppl 1), S. S126 - S126 (2019)

Bock, L. V.; Caliskan, N.; Korniy, N.; Peske, F.; Rodnina, M. V.; Grubmüller, H.: Thermodynamic control of ribosomal frameshifting. 63rd Annual Meeting of the Biophysical-Society, Baltimore, MD, 02. März 2019 - 06. März 2019. Biophysical Journal 116 (Suppl_1), S. 361A - 361A (2019)

Bock, L. V.; Grubmüller, H.: Effects of cryo-EM freezing on the structural ensemble. 62nd Annual Meeting of the Biophysical Society, San Francisco, CA, 17. Februar 2018 - 21. Februar 2018. Biophysical Journal 114 (3, Suppl. 1), S. 160a - 160a (2018)

Bock, L. V.; Kolar, M. H.; Vaiana, A. C.; Grubmüller, H.: Towards a mechanistic understanding of ribosomal function. 19th IUPAB Congress / 11th EBSA Congress, Edinburgh, Scotland, 16. Juli 2017 - 20. Juli 2017. European Biophysics Journal 46 (Suppl_1), S. S43 - S43 (2017)

Bock, L. V.; Fischer, N.; Stark, H.; Grubmüller, H.: Dynamics and energetics of elongation factor SelB in the ternary complex and the ribosome. 61st Annual Meeting of the Biophysical-Society, New Orleans, LA, 11. Februar 2017 - 15. Februar 2017. Biophysical Journal 112 (Suppl 1), 3 Aufl., S. 49a - 49a (2017)

Bock, L. V.; Huter, P. P. H.; Arenz, S.; Graf, M.; Grubmüller, H.; Wilson, D.; Vaiana, A. C.: Mechanisms of sequence dependent translational stalling. 61st Annual Meeting of the Biophysical-Society, New Orleans, LA, 11. Februar 2017 - 15. Februar 2017. Biophysical Journal 112 (Suppl 1), 3 Aufl., S. 30a - 30a (2017)

Bock, L. V.; Arenz, S.; Wilson, D. N.; Grubmüller, H.; Vaiana, A. C.: ErmBL translation on the ribosome in the presence of erythromycin is stalled by inhibition of peptide bond formation. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27. Februar 2016 - 02. März 2016. Biophysical Journal 110 (Suppl 1), 3 Aufl., S. 234A - 234A (2016)

Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Low energy barriers and a dynamic contact network between ribosomal subunits enable Rapid tRNA translocation. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27. Februar 2016 - 02. März 2016. Biophysical Journal 110 (Suppl 1), 3 Aufl., S. 3A - 3A (2016)