Suchergebnisse

Maurer, A.; Leonov, A.; Ryazanov, S.; Herfert, K.; Kuebler, L.; Buss, S.; Schmidt, F.; Weckbecker, D.; Linder, R.; Bender, D. et al.; Giese, A.; Pichler, B. J.; Griesinger, C.: ¹¹ C radiolabeling of anle253b: A putative PET tracer for Parkinson's disease that binds to α-synuclein fibrils in vitro and crosses the blood-brain barrier. ChemMedChem 15 (5), S. 411 - 415 (2020)

Mamone, S.; Rezaei-Ghaleh, N.; Opazo, F.; Griesinger, C.; Glöggler, S.: Singlet-filtered NMR spectroscopy. Science Advances 6 (8), eaaz1955 (2020)

Wong, L. E.; Bhatt, A.; Erdmann, P. S.; Hou, Z.; Maier, J.; Pirkuliyeva, S.; Engelke, M.; Becker, S.; Plitzko, J.; Wienands, J. et al.; Griesinger, C.: Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness. Nature Communications 11, 848 (2020)

Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F.; Leonov, A.; Ryazanov, S.; Griesinger, C.; Giese, A. et al.; Cauchi, R. J.; Vassallo, N.: Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin. Biochimica et Biophysica Acta. Biomembranes 1862 (2), 183064 (2020)

Smith, C. A.; Mazur, A.; Rout, A. K.; Becker, S.; Lee, D.; de Groot, B. L.; Griesinger, C.: Enhancing NMR derived ensembles with kinetics on multiple timescales. Journal of Biomolecular NMR 74, S. 27 - 43 (2020)

Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Nicolai, J.; Praest, P.; Giese, A.; Winter, R.; Khemtemourian, L.; Griesinger, C.; Killian, J. A.: The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers. Scientific Reports 9 (1), 19023 (2019)

González, N.; Gentile, I.; Garro, H. A.; Delgado-Ocaña, S.; Ramunno, C. F.; Buratti, F. A.; Griesinger, C.; Fernandez, C. O.: Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: A structural and cell-based study. Journal of Biological Inorganic Chemistry 24 (8), S. 1269 - 1278 (2019)

de Melo Sousa, C. M.; Giordani, R. B.; de Almeida, W. A. M.; Griesinger, C.; Gil, R. R.; Navarro‐Vázquez, A.; Hallwass, F.: Effect of the solvent on the conformation of monocrotaline as determined by isotropic and anisotropic NMR parameters. Magnetic Resonance in Chemistry, (in press) (2019)

Wegrzynowicz, M.; Bar-On, D.; Calo’, L.; Anichtchik, O.; Iovino, M.; Xia, J.; Ryazanov, S.; Leonov, A.; Giese, A.; Dalley, J. W. et al.; Griesinger, C.; Ashery, U.; Spillantini, M. G.: Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica 138 (4), S. 575 - 595 (2019)

Rezaei-Ghaleh, N.; Munari, F.; Becker, S.; Assfalg, M.; Griesinger, C.: A facile oxygen-17 NMR method to determine effective viscosity in dilute, molecularly crowded and confined aqueous media. Chemical Communications 55 (82), S. 12404 - 12407 (2019)

Kaltschnee, L.; Jagtap, A.; McCormick, J.; Wagner, S.; Bouchard, L. S.; Utz, M.; Griesinger, C.; Glöggler, S.: Hyperpolarization of amino acids in water utilizing parahydrogen on a rhodium nanocatalyst. Chemistry - A European Journal 25 (47), S. 11031 - 11035 (2019)

Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C.; Becker, S.; S: Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 5 (8), eaaw4988 (2019)

Brendel, M.; Deussing, M.; Blume, T.; Kaiser, L.; Probst, F.; Overhoff, F.; Peters, F.; von Ungern-Sternberg, B.; Ryazanov, S.; Leonov, A. et al.; Griesinger, C.; Zwergal, A.; Levin, J.; Bartenstein, P.; Yakushev, I.; Cumming, P.; Boening, G.; Ziegler, S.; Herms, J.; Giese, A.; Rominger, A.: Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research and Therapy 11 (1), 67 (2019)

Bartels, M.; Weckbecker, D.; Kuhn, P. H.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Lichtenthaler, S. F.; Bötzel, K.; Giese, A.: Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. Scientific Reports 9, 9100 (2019)

Heras‐Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy. Movement Disorders 34 (2), S. 255 - 263 (2019)

van Maldegem, L. M.; Sansjofre, P.; Weijers, J. W. H.; Wolkenstein, K.; Strother, P. K.; Wörmer, L.; Hefter, J.; Nettersheim, B. J.; Hoshino, Y.; Schouten, S. et al.; Damsté, J. S. S.; Nath, N.; Griesinger, C.; Kuznetsov, N. B.; Elie, M.; Elvert, M.; Tegelaar, E.; Gleixner, G.; Hallmann, C.: Bisnorgammacerane traces predatory pressure and the persistent rise of algal ecosystems after Snowball Earth. Nature Communications 10 (1), 476 (2019)

Ghio, S.; Camilleri, A.; Caruana, M.; Ruf, V. C.; Schmidt, F.; Leonov, A.; Ryazanov, S.; Griesinger, C.; Cauchi, R. J.; Kamp, F. et al.; Giese, A.; Vassallo, N.: Cardiolipin promotes pore-forming activity of alpha-synuclein oligomers in mitochondrial membranes. ACS Chemical Neuroscience 10 (8), S. 3815 - 3829 (2019)

Liu, Y.; Navarro-Vázquez, A.; Gil, R. R.; Griesinger, C.; Martin, G. E.; Williamson, R. T.: Application of anisotropic NMR parameters to the confirmation of molecular structure. Nature Protocols 14 (1), S. 217 - 247 (2019)

Wolkenstein, K.; Fuentes-Monteverde, J. C.; Nath, N.; Oji, T.; Griesinger, C.: Hypalocrinins, taurine-conjugated anthraquinone and biaryl pigments from the deep sea crinoid Hypalocrinus naresianus. Journal of Natural Products 82 (1), S. 163 - 167 (2019)

Gentile, I.; Garro, H. A.; Delgado Ocaña, S.; Gonzalez, N.; Strohäker, T.; Schibich, D.; Quintanar, L.; Sambrotta, L.; Zweckstetter, M.; Griesinger, C. et al.; Menacho Márqueza, M.; Fernandez, C. O.: Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: Binding ligands, affinity and structural features. Metallomics 10 (10), S. 1383 - 1389 (2018)