Suchergebnisse

Zeitschriftenartikel (5)

  1. 1.
    Zeitschriftenartikel
    Igaev, M.; Kutzner, C.; Bock, L. V.; Vaiana, A. C.; Grubmüller, H.: Automated cryo-EM structure refinement using correlation-driven molecular dynamics. eLife 8 (2019)
  2. 2.
    Zeitschriftenartikel
    Huter, P.; Arenz, S.; Bock, L. V.; Graf, M.; Frister, J. O.; Heuer, A.; Peil, L.; Starosta, A. L.; Wohlgemuth, I.; Peske, F. et al.; Nováček, J.; Berninghausen, O.; Grubmüller, H.; Tenson, T.; Beckmann, R.; Rodnina, M. V.; Vaiana, A. C.; Wilson, D. N.: Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 68 (3), S. 515 - 527 (2017)
  3. 3.
    Zeitschriftenartikel
    Arenz, S.; Bock, L. V.; Graf, M.; Innis, C. A.; Beckmann, R.; Grubmüller, H.; Wilson, D. N.; Vaiana, A. C.: A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. Nature Communications 7 (2016)
  4. 4.
    Zeitschriftenartikel
    Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation. Nucleic Acids Research 43 (14), S. 6747 - 6760 (2015)
  5. 5.
    Zeitschriftenartikel
    Bock, L. V.; Blau, C.; Schröder, G. F.; Davydov, I. I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), S. 1390 - 1396 (2013)

Konferenzbeitrag (18)

  1. 6.
    Konferenzbeitrag
    Bock, L. V.; Kolar, M. H.; Vaiana, A. C.; Russek, A.; von Ardenne, B.; Grubmüller, H.: Molecular basis for the extra-mitochondrial roles of cytochrome c in cell Life and death. Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, 20. Juli 2019 - 24. Juli 2019. European Biophysics Journal 48 (Suppl 1), S. S52 - S52 (2019)
  2. 7.
    Konferenzbeitrag
    Igaev, M.; Kutzner, C.; Bock, L. V.; Vaiana, A. C.; Grubmüller, H.: Automated cryo-EM structure refinement using correlation -driven molecular dynamics. Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, 20. Juli 2019 - 24. Juli 2019. European Biophysics Journal 48 (Suppl 1), S. S126 - S126 (2019)
  3. 8.
    Konferenzbeitrag
    Vaiana, A. C.; Igaev, M.; Kutzner, C.; Grubmüller, H.: Fully automated correlation-based refinement of atomic models into high resolution cryo-EM density maps. 62nd Annual Meeting of the Biophysical-Society, San Francisco, CA, 17. Februar 2018 - 21. Februar 2018. Biophysical Journal 114 (3), S. 161a - 161a (2018)
  4. 9.
    Konferenzbeitrag
    Bock, L. V.; Kolar, M. H.; Vaiana, A. C.; Grubmüller, H.: Towards a mechanistic understanding of ribosomal function. 19th IUPAB Congress / 11th EBSA Congress, Edinburgh, Scotland, 16. Juli 2017 - 20. Juli 2017. European Biophysics Journal 46 (Suppl_1), S. S43 - S43 (2017)
  5. 10.
    Konferenzbeitrag
    Bock, L. V.; Huter, P. P. H.; Arenz, S.; Graf, M.; Grubmüller, H.; Wilson, D.; Vaiana, A. C.: Mechanisms of sequence dependent translational stalling. 61st Annual Meeting of the Biophysical-Society, New Orleans, LA, 11. Februar 2017 - 15. Februar 2017. Biophysical Journal 112 (Suppl 1), S. 30a - 30a (2017)
  6. 11.
    Konferenzbeitrag
    Bock, L. V.; Arenz, S.; Wilson, D. N.; Grubmüller, H.; Vaiana, A. C.: ErmBL translation on the ribosome in the presence of erythromycin is stalled by inhibition of peptide bond formation. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27. Februar 2016 - 02. März 2016. Biophysical Journal 110 (Suppl 1), S. 234A - 234A (2016)
  7. 12.
    Konferenzbeitrag
    Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Low energy barriers and a dynamic contact network between ribosomal subunits enable Rapid tRNA translocation. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27. Februar 2016 - 02. März 2016. Biophysical Journal 110 (Suppl 1), S. 3A - 3A (2016)
  8. 13.
    Konferenzbeitrag
    Blau, C.; Bock, L.; Kutzner, C.; Vaiana, A.; Grubmüller, H.: Bayesian cryo-EM refinement. 59th Annual Meeting of the Biophysical-Society, Baltimore/MD, 07. Februar 2015 - 11. Februar 2015. Biohysical Journal 108 (Suppl. 1), S. 470a - 470a (2015)
  9. 14.
    Konferenzbeitrag
    Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Balanced interactions between ribosomal subunits allow rapid large-scale rotation. Biophysical Journal 108 (Suppl. 1), S. 26A - 26A (2015)
  10. 15.
    Konferenzbeitrag
    Vaiana, A. C.; Kutzner, C.; Bock, L. V.; Blau, C.; Grubmüller, H.: Structural determinants of hybrid state intermediates of the bacterial ribosome. 59th Annual Meeting of the Biophysical-Society, Baltimore, 07. Februar 2015 - 11. Februar 2015. Biophysical Journal 108 (Supplement 1), S. 318a - 318a (2015)
  11. 16.
    Konferenzbeitrag
    Blau, C.; Bock, L. V.; Schröder, G. F.; Davydov, I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Ribosomal kinetics and concerted motions from nanoseconds to seconds. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15. Februar 2014 - 19. Februar 2014. Biophysical Journal 106 (2, Suppl. 1), S. 250a (2014)
  12. 17.
    Konferenzbeitrag
    Bock, L. V.; Blau, C.; Vaiana, A. C.; Grubmüller, H.: Concerted interactions between ribosomal subunits allow for large-scale rotations. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15. Februar 2014 - 19. Februar 2014. Biophysical Journal 106 (Supplement 1), S. 491a - 491a (2014)
  13. 18.
    Konferenzbeitrag
    Bock, L. V.; Blau, C.; Schröder, G. F.; Davydov, I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Rapid and stable transfer RNA translocation through the ribosome ensured by specific contact mechanisms. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15. Februar 2014 - 19. Februar 2014. Biophysical Journal 106 (Supplement 1), S. 493a - 493a (2014)
  14. 19.
    Konferenzbeitrag
    Vaiana, A. C.; Kutzner, C.; Bock, L. V.; Blau, C.; Grubmüller, H.: Refining crystal structures against Cryo-EM data using molecular dynamics simulations to obtain a complete atomistic pathway of transfer RNA translocation. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15. Februar 2014 - 19. Februar 2014. Biophysical Journal 106 (Supplement 1), S. 240a - 240a (2014)
  15. 20.
    Konferenzbeitrag
    Blau, C.; Bock, L. V.; Schröder, G.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Rate estimates from sampling sparse transitions: TRNA motion limits transitions between ribosomal translocation intermediates. 57th Annual Meeting of the Biophysical-Society, Philadelphia/PA, 02. Februar 2013 - 06. Februar 2013. Biophysical Journal 104 (Supplement 1), S. 663A - 663A (2013)
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