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Zeitschriftenartikel (10)
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1.ZeitschriftenartikelPrp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 69 (6), S. 979 - 992 (2018)
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2.ZeitschriftenartikelThe large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development 29 (24), S. 2576 - 2587 (2015)
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3.ZeitschriftenartikelA composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife 4 (2015)
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4.ZeitschriftenartikelThe G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development 29 (1), S. 94 - 107 (2015)
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5.ZeitschriftenartikelNovel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology 11 (4), S. 298 - 312 (2014)
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6.ZeitschriftenartikelInhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science 341 (6141), S. 80 - 84 (2013)
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7.ZeitschriftenartikelStructural basis for dual roles of Aar2p in U5 snRNP assembly. Genes and Development 27 (5), S. 525 - 540 (2013)
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8.ZeitschriftenartikelThe Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes and Development 26 (23), S. 2422 - 2434 (2012)
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9.ZeitschriftenartikelStructural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proceedings of the National Academy of Sciences of the United States of America 109 (43), S. 17418 - 17423 (2012)
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10.ZeitschriftenartikelCommon design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Molecular Cell 35 (4), S. 454 - 466 (2009)
Konferenzbeitrag (2)
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11.KonferenzbeitragThe ciliopathy protein SANS (Usher syndrome 1G) regulates pre-mRNA splicing by facilitating the maturation of the spliceosomal tri-snRNP complex. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, Canada, 28. April 2019 - 02. Mai 2019. Investigative Ophthalmology and Visual Science 60 (9), (2019)
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12.KonferenzbeitragHuman iPSC-derived RPE and retinal organoids reveal impaired alternative splicing of genes involved in pre-mRNA splicing in PRPF31 autosomal dominant retinitis pigmentosa. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honululu, Haiti, 29. April 2018 - 03. Mai 2018. Investigative Ophthalmology and Visual Science 59 (9), (2018)
Hochschulschrift - Doktorarbeit (1)
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13.Hochschulschrift - DoktorarbeitMechanism of regulation of spliceosome activation by Brr2 and Prp8 and links to retinal disease. Dissertation, VI, 57 S., Georg-August-Universität, Göttingen (2013)