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Zeitschriftenartikel (88)
1.
Zeitschriftenartikel
587 (7832), S. 157 - 161 (2020)
Atomic-resolution protein structure determination by cryo-EM. Nature 2.
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80 (1), S. 127 - 139.e6 (2020)
Structural insights into the roles of metazoan-specific splicing factors in the human step 1 spliceosome. Molecular Cell 3.
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583 (7815), S. 310 - 313 (2020)
Molecular architecture of the human 17S U2 snRNP. Nature 4.
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180 (6), S. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 5.
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11 (11), a032417 (2019)
Structural insights into nuclear pre-mRNA splicing in higher eukaryotes. Cold Spring Harbor Perspectives in Biology 6.
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116 (35), S. 17280 - 17289 (2019)
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proceedings of the National Academy of Sciences of the United States of America 7.
Zeitschriftenartikel
27 (7), S. 1124 - 1136 (2019)
Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 8.
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29 (2), S. 117 - 134 (2019)
Posing the APC/C E3 ubiquitin ligase to orchestrate cell division. Trends in Cell Biology 9.
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17 (7), S. 471 - 492 (2018)
Cryo-EM in drug discovery: Achievements, limitations and prospects. Nature Reviews Drug Discovery 10.
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172 (3), S. 454 - 464, e1-e5 (2018)
Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 11.
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170 (4), S. 701 - 713, e1 - e4 (2017)
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 12.
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8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications 13.
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372 (1716), 20160182 (2017)
Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 14.
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542 (7641), S. 318 - 323 (2017)
Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 15.
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540 (7631), S. 80 - 85 (2016)
The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 16.
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353 (6306), S. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 17.
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16 (12), S. 3103 - 3112 (2016)
The ribosome cooperates with the assembly chaperone pICln to initiate formation of snRNPs. Cell Reports 18.
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7, 12523 (2016)
Topology and structure of an engineered human cohesin complex bound to Pds5B. Nature Communications 19.
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63 (4), S. 593 - 607 (2016)
Cryo-EM of mitotic checkpoint complex-bound APC/C reveals reciprocal and conformational regulation of ubiquitin ligation. Molecular Cell 20.
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353 (6299), S. 594 - 598 (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science