Journal Article (363)

101.
Journal Article
Watson, E. R.; Grace, C. R. R.; Zhang, W.; Miller, D. J.; Davidson, I. F.; Prabu, J. R.; Yu, S.; Bolhuis, D. L.; Kulko, E. T.; Vollrath, R. et al.; Haselbach, D.; Stark, H.; Peters, J. M.; Brown, N. G.; Sidhu, S. S.; Schulman, B. A.: Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proceedings of the National Academy of Sciences of the United States of America 116 (35), pp. 17280 - 17289 (2019)
102.
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Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)
103.
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Bryen, S. J.; Joshi, H.; Evesson, F. J.; Girard, C.; Ghaoui, R.; Waddell, L. B.; Testa, A. C.; Cummings, B.; Arbuckle, S.; Graf, N. et al.; Webster, R.; MacArthur, D. G.; Laing, N. G.; MR, D.; Lührmann, R.; Cooper, S. T.: Pathogenic abnormal splicing due to intronic deletions that induce biophysical space constraint for spliceosome assembly. American Journal of Human Genetics 105 (3), pp. 573 - 587 (2019)
104.
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Kaltschnee, L.; Jagtap, A.; McCormick, J.; Wagner, S.; Bouchard, L. S.; Utz, M.; Griesinger, C.; Glöggler, S.: Hyperpolarization of amino acids in water utilizing parahydrogen on a rhodium nanocatalyst. Chemistry - A European Journal 25 (47), pp. 11031 - 11035 (2019)
105.
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Park, G. B.; Krüger, B. C.; Borodin, D.; Kitsopoulos, T.; Wodtke, A. M.: Fundamental mechanisms for molecular energy conversion and chemical reactions at surfaces. Reports on Progress in Physics 82 (9), 09640 (2019)
106.
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Alsina, K. M.; Hulsurkar, M.; Brandenburg, S.; Kownatzki-Danger, D.; Lenz, C.; Urlaub, H.; Abu-Taha, I.; Kamler, M.; Chiang, D. Y.; Lahiri, S. K. et al.; Reynolds, J. O.; Quick, A. P.; Scott, L.; Word, T. A.; Gelves, M. D.; Heck, A. J. R.; Li, N.; Dobrev, D.; Lehnart, S. E.; Wehrens, X. H. T.: Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 140 (8), pp. 681 - 693 (2019)
107.
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Mahamid, J.; Tegunov, D.; Maiser, A.; Arnold, J.; Leonhardt, H.; Plitzko, J. M.; Baumeister, W.: Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), pp. 16866 - 16871 (2019)
108.
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Mirdita, M.; Steinegger, M.; Söding, J.: MMseqs2 desktop and local web server app for fast, interactive sequence searches. Bioinformatics 35 (16), pp. 2856 - 2858 (2019)
109.
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Keiper, S. M.; Papasaikas, P.; Will, C. L.; Valcárcel, J.; Girard, C.; Lührmann, R.: Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns. Nature Communications 10 (1), 3639 (2019)
110.
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Gressel, S.; Schwalb, B.; Cramer, P.: The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1), 3603 (2019)
111.
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Modena, M. M.; Rühle, B.; Burg, T. P.; Wuttke, S.: Nanoparticle characterization: What to measure? Advanced Materials 31 (32), 1901556 (2019)
112.
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Diehn, M.; Munk, A.; Rudolf, D.: Maximum likelihood estimation in hidden Markov models with inhomogeneous noise. ESAIM: Probability and Statistics 23, pp. 492 - 523 (2019)
113.
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Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C.; Becker, S.; S: Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 5 (8), eaaw4988 (2019)
114.
Journal Article
Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Yu, L.; Roumeliotis, T. I.; Diebold, M.; Dybkov, O.; Sotriffer, C.; Urlaub, H.; Choudhary, J. S. et al.; Mansfeld, J.; Lorenz, S.: Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 27 (8), pp. 1195 - 1210 (2019)
115.
Journal Article
Khan, N.; Shah, P. P.; Ban, D.; Trigo-Mouriño, P.; Carneiro, M. G.; DeLeeuw, L.; Dean, W. L.; Trent, J. O.; Beverly, L. J.; Konrad, M. et al.; Lee, D.; Sabo, T. M.: Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer. The Journal of Biological Chemistry 294 (31), pp. 11920 - 11933 (2019)
116.
Journal Article
Arakel, E. C.; Huranova, M.; Estrada, A. F.; Rau, E. M.; Spang, A.; Schwappach, B.: Dissection of GTPase activating proteins reveals functional asymmetry in the COPI coat of budding yeast. Journal of Cell Science 132 (16), jcs232124 (2019)
117.
Journal Article
Brendel, M.; Deussing, M.; Blume, T.; Kaiser, L.; Probst, F.; Overhoff, F.; Peters, F.; von Ungern-Sternberg, B.; Ryazanov, S.; Leonov, A. et al.; Griesinger, C.; Zwergal, A.; Levin, J.; Bartenstein, P.; Yakushev, I.; Cumming, P.; Boening, G.; Ziegler, S.; Herms, J.; Giese, A.; Rominger, A.: Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research and Therapy 11 (1), 67 (2019)
118.
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Hehlert, P.; Hofferek, V.; Heier, C.; Eichmann, T. O.; Riedel, D.; Rosenberg, J.; Takacs, A.; Nagy, H. M.; Oberer, M.; Zimmermann, R. et al.; Kühnlein, R. P.: The α/β-hydrolase domain-containing 4 and 5 (ABHD4/5)-related phospholipase Pummelig controls energy storage in Drosophila. Journal of Lipid Research 60 (8), pp. 1365 - 1378 (2019)
119.
Journal Article
Krüger, B. C.; Schäfer, T.; Wodtke, A. M.; Park, G. B.: Quantum-state resolved lifetime of triplet (ã3A2) formaldehyde. Journal of Molecular Spectroscopy 362, pp. 61 - 68 (2019)
120.
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Lerchundi, R.; Kafitz, K. W.; Winkler, U.; Färfers, M.; Hirrlinger, J.; Rose, C. R.: FRET-based imaging of intracellular ATP in organotypic brain slices. Journal of Neuroscience Research 97 (8), pp. 933 - 945 (2019)
121.
Journal Article
Najbauer, E.; Andreas, L. B.: Correcting for magnetic field drift in magic-angle spinning NMR datasets. Journal of Magnetic Resonance 305, pp. 1 - 4 (2019)
122.
Journal Article
Pavlova, E. V.; Shatunov, A.; Wartosch, L.; Moskvina, A. I.; Nikolaeva, L. E.; Bright, N. A.; Tylee, K. L.; Church, H. J.; Ballabio, A.; Luzio, J. P. et al.; Cox, T. M.: The lysosomal disease caused by mutant VPS33A. Human Molecular Genetics 28 (15), pp. 2514 - 2530 (2019)
123.
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Öster, C.; Hendriks, K.; Kopec, W.; Chevelkov, V.; Shi, C.; Michl, D.; Lange, S.; Sun, H.; de Groot, B. L.; Lange, A.: The conduction pathway of potassium channels is water free under physiological conditions. Science Advances 5 (7), eaaw6756 (2019)
124.
Journal Article
So, C.; Seres, K. B.; Steyer, A. M.; Mönnich, E.; Clift, D.; Pejkovska, A.; Möbius, W.; Schuh, M.: A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science 364 (6447), eaat9557 (2019)
125.
Journal Article
Frahm, L.; Keller, J.; Alt, P.; Schnorrenberg, S.; Ruiz, M. D.; Aspelmeier, T.; Munk, A.; Jakobs, S.; Hell, S. W.: Molecular contribution function in RESOLFT nanoscopy. Optics Express 27 (15), pp. 21956 - 21987 (2019)
126.
Journal Article
Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1), 3138 (2019)
127.
Journal Article
Koopmans, F.; van Nierop, P.; Andres-Alonso, M.; Byrnes, A.; Cijsouw, T.; Coba, M. P.; Cornelisse, L. N.; Farrell, R. J.; Goldschmidt, H. L.; Howrigan, D. P. et al.; Hussain, N. K.; Imig, C.; de Jong, A. P.H.; Jung, H.; Kohansalnodehi, M.; Kramarz, B.; Lipstein, N.; Lovering, R. C.; MacGillavry, H.; Mariano, V.; Mi, H.; Ninov, M.; Osumi-Sutherland, D.; Pielot, R.; Smalla, K.-H.; Tang, H.; Tashman, K.; Toonen, R. F.G.; Verpelli, C.; Reig-Viader, R.; Watanabe, K.; van Weering, J.; Achsel, T.; Ashrafi, G.; Asi, N.; Brown, T. C.; Camilli, P. D.; Feuermann, M.; Foulger, R. E.; Gaudet, P.; Joglekar, A.; Kanellopoulos, A.; Malenka, R.; Nicoll, R. A.; Pulido, C.; de Juan-Sanz, J.; Sheng, M.; Südhof, T. C.; Tilgner, H. U.; Bagni, C.; Bayés, À.; Biederer, T.; Brose, N.; Chua, J. J. E.; Dieterich, D. C.; Gundelfinger, E. D.; Hoogenraad, C.; Huganir, R. L.; Jahn, R.; Kaeser, P. S.; Kim, E.; Kreutz, M. R.; McPherson, P. S.; Neale, B. M.; O’Connor, V.; Posthuma, D.; Ryan, T. A.; Sala, C.; Feng, G.; Hyman, S. E.; Thomas, P. D.; Smit, A. B.; Verhage, M.: SynGO: An evidence-based, expert-curated knowledge base for the synapse. Neuron 103, 10.1016/j.neuron.2019.05.002 (2019)
128.
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Koopmans, F.; van Nierop, P.; Andres-Alonso, M.; Byrnes, A.; Cijsouw, T.; Coba, M. P.; Cornelisse, L. N.; Farrell, R. J.; Goldschmidt, H. L.; Howrigan, D. P. et al.; Hussain, N. K.; Imig, C.; de Jong, A. P. H.; Jung, H.; Kohansalnodehi, M.; Kramarz, B.; Lipstein, N.; Lovering, R. C.; MacGillavry, H.; Mariano, V.; Mi, H.; Ninov, M.; Osumi-Sutherland, D.; Pielot, R.; Smalla, K. H.; Tang, H.; Tashman, K.; Toonen, R. F. G.; Verpelli, C.; Reig-Viader, R.; Watanabe, K.; van Weering, J.; Achsel, T.; Ashrafi, G.; Asi, N.; Brown, T. C.; De Camilli, P.; Feuermann, M.; Foulger, R. E.; Gaudet, P.; Joglekar, A.; Kanellopoulos, A.; Malenka, R.; Nicoll, R. A.; Pulido, C.; de Juan-Sanz, J.; Sheng, M.; Südhof, T. C.; Tilgner, H. U.; Bagni, C.; Bayés, A.; Biederer, T.; Brose, N.; Chua, J. J. E.; Dieterich, D. C.; Gundelfinger, E. D.; Hoogenraad, C.; Huganir, R. L.; Jahn, R.; Kaeser, P. S.; Kim, E.; Kreutz, M. R.; McPherson, P. S.; Neale, B. M.; O’Connor, V.; Posthuma, D.; Ryan, T. A.; Sala, C.; Feng, G.; Hyman, S. E.; Thomas, P. D.; Smit, A. B.; Verhage, M.: SynGO: An evidence-based, expert-curated knowledge base for the synapse. Neuron 103 (2), pp. 217 - 234 (2019)
129.
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Ambadipudi, S.; Reddy,, J. G.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau. Chemical Science 10 (26), pp. 6503 - 6507 (2019)
130.
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Callegari, S.; Müller, T.; Schulz, C.; Lenz, C.; Jans, D. C.; Wissel, M.; Opazo, F.; Rizzoli, S. O.; Jakobs, S.; Urlaub, H. et al.; Rehling, P.; Deckers, M.: A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 431 (15), pp. 2835 - 2851 (2019)
131.
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Petkau, N.; Budak, H.; Zhou, X.; Oster, H.; Eichele, G.: Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. eLife 8, e43235 (2019)
132.
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Joseph, S.; Vingill, S.; Jahn, O.; Fledrich, R.; Werner, H. B.; Katona, I.; Möbius, W.; Mitkovski, M.; Huang, Y.; Weis, J. et al.; Sereda, M. W.; Schulz, J. B.; Nave, K.-A.; Stegmüller, J.: Myelinating glia-specific deletion of Fbxo7 in mice triggers axonal degeneration in the central nervous system together with peripheral neuropathy. The Journal of Neuroscience 39 (28), pp. 5606 - 5626 (2019)
133.
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Chen, Y.; Cramer, P.: Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, pp. 10663 - 10673 (2019)
134.
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Sommerfeld, M.; Schrieber, J.; Zemel, Y.; Munk, A.: Optimal transport: Fast probabilistic approximation with exact solvers. The Journal of Machine Learning Research 20, (in press) (2019)
135.
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Sherrill, H. E.; Jean, P.; Driver, E. C.; Sanders, T. R.; Fitzgerald, T. S.; Moser, T.; Kelley, M. W.: Pou4f1 defines a subgroup of type I spiral ganglion neurons and is necessary for normal inner hair cell presynaptic Ca2+ signaling. The Journal of Neuroscience 39 (27), pp. 5284 - 5298 (2019)
136.
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Prajapati, S.; Haselbach, D.; Wittig, S.; Patel, M. S.; Chari, A.; Schmidt, C.; Stark, H.; Tittmann, K.: Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 27 (7), pp. 1124 - 1136 (2019)
137.
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Szegö, É. M.; Dominguez-Meijide, A.; Gerhardt, E.; König, A.; Koss, D. J.; Li, W.; Pinho, R.; Fahlbusch, C.; Johnson, M.; Santos, P. et al.; Villar-Piqué, A.; Thom, T.; Rizzoli, S.; Schmitz, M.; Li, J.; Zerr, I.; Attems, J.; Jahn, O.; Outeiro, T. F.: Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 28, pp. 65 - 77 (2019)
138.
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Ukmar-Godec, T.; Hutten, S.; Grieshop, M. P.; Rezaei-Ghaleh, N.; Cima-Omori, M. O.; Biernat, J.; Mandelkow, E.; Söding, J.; Dormann, D.; Zweckstetter, M.: Lysine/RNA-interactions drive and regulate biomolecular condensation. Nature Communications 10 (1), 2909 (2019)
139.
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Garcia-Agudo, L. F.; Janova, H.; Sendler, L. E.; Arinrad, S.; Steixner, A. A.; Hassouna, I.; Balmuth, E.; Ronnenberg, A.; Schopf, N.; van der Flier, F. J. et al.; Begemann, M.; Martens, H.; Weber, M. S.; Boretius, S.; Nave, K.-A.; Ehrenreich, H.: Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. The FASEB Journal 33 (7), pp. 8634 - 8647 (2019)
140.
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Hwang, S.; Öster, C.; Chevelkov, V.; Giller, K.; Lange, S.; Becker, S.; Lange, A.: Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations. Journal of Biomolecular NMR 73 (6-7), pp. 281 - 291 (2019)
141.
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Khachikyan, A.; Milucka, J.; Littmann, S.; Ahmerkamp, S.; Meador, T.; Könneke, M.; Burg, T.; Kuypers, M. M. M.: Direct cell mass measurements expand the role of small microorganisms in nature. Methods 85 (4), e00493-19 (2019)
142.
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Korniy, N.; Samatova, E. N.; Anokhina, M. M.; Peske, F.; Rodnina, M. V.: Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), pp. 1468 - 1482 (2019)
143.
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Nicolas, J.-D.; Bernhardt, M.; Schlick, S. F.; Tiburcy, M.; Zimmermann, W.-H.; Khan, A.; Markus, A.; Alves, F.; Toischer, K.; Salditt, T.: X-ray diffraction imaging of cardiac cells and tissue. Progress in Biophysics and Molecular Biology 144, pp. 151 - 165 (2019)
144.
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Pump, W. C.; Schulz, R.; Huyton, T.; Kunze-Schumacher, H.; Martens, J.; Ho, G. G. T.; Blasczyk, R.; Bade-Doeding, C.: Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity. HLA: Immune Response Genetics 94 (1), pp. 25 - 38 (2019)
145.
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Ranjan, N.; Leidel, S. A.: The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 593 (13), pp. 1483 - 1493 (2019)
146.
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Saito, M.; Koike, S.; Holm, K.; Bregolin, F. L.; Hofsäss, H.: External RBS/PIXE analysis for evaluating quantum dots internalization into HeLa cells. Nuclear Instruments and Methods in Physics Research B 450, pp. 173 - 178 (2019)
147.
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Steinegger, M.; Mirdita, M.; Söding, J.: Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold. Nature Methods 16, pp. 603 - 606 (2019)
148.
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Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A.; Spieth, L.; Düking, T.; Schneider, L. V.; Schlaphoff, L.; Dreha-Kulaczewski, S.; Bley, A.; Burfeind, D. et al.; Kusch, K.; Mitkovski, M.; Ruhwedel, T.; Guder, P.; Röhse, H.; Denecke, J.; Gärtner, J.; Möbius, W.; Nave, K.-A.; Saher, G.: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica 138, pp. 147 - 161 (2019)
149.
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Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)
150.
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Rossetti, G.; Kless, A.; Lai, L.; Outeiro, T. F.; Carloni, P.: Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions 47, pp. 909 - 918 (2019)
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