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Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proceedings of the National Academy of Sciences of the United States of America 102.
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Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 103.
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Pathogenic abnormal splicing due to intronic deletions that induce biophysical space constraint for spliceosome assembly. American Journal of Human Genetics 104.
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25 (47), pp. 11031 - 11035 (2019)
Hyperpolarization of amino acids in water utilizing parahydrogen on a rhodium nanocatalyst. Chemistry - A European Journal 105.
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82 (9), 09640 (2019)
Fundamental mechanisms for molecular energy conversion and chemical reactions at surfaces. Reports on Progress in Physics 106.
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Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 107.
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116 (34), pp. 16866 - 16871 (2019)
Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 108.
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35 (16), pp. 2856 - 2858 (2019)
MMseqs2 desktop and local web server app for fast, interactive sequence searches. Bioinformatics 109.
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Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns. Nature Communications 110.
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The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 111.
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Nanoparticle characterization: What to measure? Advanced Materials 112.
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Maximum likelihood estimation in hidden Markov models with inhomogeneous noise. ESAIM: Probability and Statistics 113.
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Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 114.
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Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 115.
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Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer. The Journal of Biological Chemistry 116.
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132 (16), jcs232124 (2019)
Dissection of GTPase activating proteins reveals functional asymmetry in the COPI coat of budding yeast. Journal of Cell Science 117.
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11 (1), 67 (2019)
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research and Therapy 118.
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60 (8), pp. 1365 - 1378 (2019)
The α/β-hydrolase domain-containing 4 and 5 (ABHD4/5)-related phospholipase Pummelig controls energy storage in Drosophila. Journal of Lipid Research 119.
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362, pp. 61 - 68 (2019)
Quantum-state resolved lifetime of triplet (ã3A2) formaldehyde. Journal of Molecular Spectroscopy 120.
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97 (8), pp. 933 - 945 (2019)
FRET-based imaging of intracellular ATP in organotypic brain slices. Journal of Neuroscience Research 121.
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305, pp. 1 - 4 (2019)
Correcting for magnetic field drift in magic-angle spinning NMR datasets. Journal of Magnetic Resonance 122.
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28 (15), pp. 2514 - 2530 (2019)
The lysosomal disease caused by mutant VPS33A. Human Molecular Genetics 123.
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5 (7), eaaw6756 (2019)
The conduction pathway of potassium channels is water free under physiological conditions. Science Advances 124.
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A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science 125.
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27 (15), pp. 21956 - 21987 (2019)
Molecular contribution function in RESOLFT nanoscopy. Optics Express 126.
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NASC-seq monitors RNA synthesis in single cells. Nature Communications 127.
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SynGO: An evidence-based, expert-curated knowledge base for the synapse. Neuron 128.
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SynGO: An evidence-based, expert-curated knowledge base for the synapse. Neuron 129.
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Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau. Chemical Science 130.
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A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 131.
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Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. eLife 132.
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39 (28), pp. 5606 - 5626 (2019)
Myelinating glia-specific deletion of Fbxo7 in mice triggers axonal degeneration in the central nervous system together with peripheral neuropathy. The Journal of Neuroscience 133.
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294, pp. 10663 - 10673 (2019)
Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 134.
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Optimal transport: Fast probabilistic approximation with exact solvers. The Journal of Machine Learning Research 135.
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Pou4f1 defines a subgroup of type I spiral ganglion neurons and is necessary for normal inner hair cell presynaptic Ca2+ signaling. The Journal of Neuroscience 136.
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Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 137.
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28, pp. 65 - 77 (2019)
Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 138.
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Lysine/RNA-interactions drive and regulate biomolecular condensation. Nature Communications 139.
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Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. The FASEB Journal 140.
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73 (6-7), pp. 281 - 291 (2019)
Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations. Journal of Biomolecular NMR 141.
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85 (4), e00493-19 (2019)
Direct cell mass measurements expand the role of small microorganisms in nature. Methods 142.
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Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 143.
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144, pp. 151 - 165 (2019)
X-ray diffraction imaging of cardiac cells and tissue. Progress in Biophysics and Molecular Biology 144.
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94 (1), pp. 25 - 38 (2019)
Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity. HLA: Immune Response Genetics 145.
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The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 146.
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450, pp. 173 - 178 (2019)
External RBS/PIXE analysis for evaluating quantum dots internalization into HeLa cells. Nuclear Instruments and Methods in Physics Research B 147.
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Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold. Nature Methods 148.
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Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica 149.
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Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 150.
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Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions