Department of Molecular Biology Seminar Series: Epigenetic Regulation of Tumor Cell Plasticity and Therapeutic Responsiveness

Department of Molecular Biology Seminar Series

  • Date: Apr 26, 2018
  • Time: 13:00 - 14:00
  • Speaker: Steven Johnsen
  • University Medical Center Göttingen
  • Location: Max-Planck-Institut für biophysikalische Chemie (MPIBPC)
  • Room: Tower IV, Seminar Room, 2nd Floor
  • Host: Prof. Dr. Patrick Cramer
  • Contact: office.cramer@mpibpc.mpg.de
Department of Molecular Biology Seminar Series: Epigenetic Regulation of Tumor Cell Plasticity and Therapeutic Responsiveness
Tumor cells utilize a very diverse array of mechanisms to proliferate uncontrolled, evade therapy and metastasize. Irrespective of the underlying cause of a tumor, essentially all tumor-specific changes ultimately converge in the altered expression of genes in the cell. The goal of our work is to understand the epigenetic and transcriptional regulatory processes by which tumor-specific changes in gene activity lead to tumorigenesis and tumor progression. More importantly, we aim to utilize this information to identify better and more efficient therapies for various gastrointestinal tumors.
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