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Zeitschriftenartikel (90)
41.
Zeitschriftenartikel
15 (12), S. 1555 - 1566 (2007)
Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes. Structure 42.
Zeitschriftenartikel
282 (30), S. 22112 - 22121 (2007)
Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation. Journal of Biological Chemistry 43.
Zeitschriftenartikel
50 (13), S. 3004 - 3014 (2007)
Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-Nucleosides. Journal of Medicinal Chemistry 44.
Zeitschriftenartikel
369 (1), S. 129 - 141 (2007)
Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. Journal of Molecular Biology 45.
Zeitschriftenartikel
367 (2), S. 488 - 500 (2007)
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1. Journal of Molecular Biology 46.
Zeitschriftenartikel
35, S. 186 - 192 (2007)
Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase. Nucleic Acids Research 47.
Zeitschriftenartikel
15 (5), S. 962 - 970 (2007)
Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Molecular Therapy 48.
Zeitschriftenartikel
364 (2), S. 136 - 151 (2006)
Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine. Journal of Molecular Biology 49.
Zeitschriftenartikel
45 (2), S. 452 - 461 (2006)
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: Illuminating the role of main-chain reorganization. Biochemistry 50.
Zeitschriftenartikel
86, S. 757 - 764 (2005)
Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition. Journal of General Virology 51.
Zeitschriftenartikel
279 (32), S. 33882 - 33889 (2004)
Substrate-induced conformational changes in human UMP/CMP kinase. Journal of Biological Chemistry 52.
Zeitschriftenartikel
4 (4), S. 351 - 359 (2004)
Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase. Mini-Reviews in Medicinal Chemistry 53.
Zeitschriftenartikel
279 (18), S. 18203 - 18209 (2004)
Tropomyosin exon 6b is troponin-specific and required for correct acto-myosin regulation. Journal of Biological Chemistry 54.
Zeitschriftenartikel
310 (4), S. 1104 - 1110 (2003)
Liposomes for microcompartmentation of enzymes and their influence on catalytic activity. Biochemical and Biophysical Research Communications 55.
Zeitschriftenartikel
11 (10), S. 1265 - 1277 (2003)
Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure 56.
Zeitschriftenartikel
10 (7), S. 513 - 519 (2003)
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nature Structural Biology 57.
Zeitschriftenartikel
42 (9), S. 2568 - 2577 (2003)
Structures of human thymidylate kinase in complex with prodrugs: Implications for the structure-based design of novel compounds. Biochemistry 58.
Zeitschriftenartikel
4 (2-3), S. 143 - 146 (2003)
Modulated nucleoside kinases as tools to improve the activation of therapeutic nucleoside analogues. ChemBioChem 59.
Zeitschriftenartikel
277 (43), S. 40832 - 40838 (2002)
Formation of complexes between Ca2+center dot calmodulin and the synapse-associated protein SAP97 requires the SH3 domain- guanylate kinase domain-connecting HOOK region. Journal of Biological Chemistry 60.
Zeitschriftenartikel
277 (33), S. 30236 - 30243 (2002)
Structural characterization of the closed conformation of mouse guanylate kinase. Journal of Biological Chemistry