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Research News and Awards

Press Releases

Teaser 1519030170

Sir Bernard Katz Award for Manfred Lindau

February 19, 2018
Manfred Lindau, research group leader at the MPI for Biophysical Chemistry, received this year's Sir Bernard Katz Award of the American Biophysical Society for his outstanding contributions in the field of signal transduction in neurons. The award ceremony took place on February 17, 2018, in San Francisco, USA. (in German) [more]
Teaser 1516965735

Optical measurement of the synaptic nanoworld

January 26, 2018
Scientists from Göttingen with participation of the MPI for Biophysical Chemistry develop high-resolution measurements of the calcium concentration and decipher the number and function of calcium channels at the synapse. (in German) [more]
Teaser 1516710564

Switching on genes for energy production

January 23, 2018
A research team at the MPI for Biophysical Chemistry together with colleagues at Rowan University (USA) has structurally visualized how the accessory factors of the mitochondrial RNA polymerase enable mitochondrial transcription during initiation and elongation. Together with functional data, the structures resulted in a movie of transcription in human mitochondria and demonstrate how this process differs from transcription in the cell nucleus. [more]
Teaser 1513784708

Fewer laboratory animals thanks to secondary nanobodies

December 20, 2017
Antibodies are indispensable in biological research and medical diagnostics. However, their production is time-consuming, expensive, and requires the use of many animals. Scientists at the MPI for Biophysical Chemistry in Göttingen, Germany, have now developed so-called secondary nanobodies that can replace the most-used antibodies and may drastically reduce the number of animals in antibody production. [more]
Teaser 1513674065

Experimental drug interferes with different mechanisms associated to Alzheimer’s disease

December 19, 2017
The chemical compound anle138b eases cognitive deficits and normalizes gene expression in a mouse model of Alzheimer’s disease and it seems to close harmful openings in the membrane of nerve cells as an international team of researchers including researchers of the MPI for Biophysical Chemistry found out. The scientists suggest that anle138b should be validated in clinical trials for its potential to treat Alzheimer’s and further neurodegenerative diseases. [more]
Teaser 1513168951

MINFLUX is listed as one of the Top Ten Breakthroughs of 2017 by Physics World

December 13, 2017
MINFLUX nanoscopy by Stefan Hell is in the Physics World Top Ten Breakthroughs of 2017. The super-resolution microscope reaches nanometer-scale resolution in living cells for the first time and has a very high temporal resolution. [more]
Teaser 1511959546

ERC Consolidator Grant for Thomas Burg

November 29, 2017
The Göttingen scientist Thomas Burg was awarded a Consolidator Grant of the European Research Council. His work will be funded with 2 million Euros over the next five years. Together with his research group at the MPI for Biophysical Chemistry, Burg wants to establish a method which allows the combination of live-cell with cryo microscopy with a very high temporal resolution. This progress shall help to better understand dynamic cellular processes and, thus, provide new insights for cancer research, pharmacology, and neurosciences. (in German) [more]
Teaser 1510851754

To trim away a protein

November 16, 2017
To remove a protein from a cell, researchers can currently typically use two methods: genome editing by CRISPR/Cas, and RNA interference. They act on the level of DNA or RNA, respectively. However, their influence on protein amounts is indirect and takes time. German and UK scientists now present a new method, Trim-Away, which makes it possible to directly and quickly deplete a protein from any cell type. As Trim-Away can distinguish between different variants of a protein, it also opens up new venues for the therapy of diseases. [more]
Teaser 1510067734

New protein analysis technique based on work by Holger Stark and Ashwin Chari licensed

November 07, 2017
ProteoPlex has exclusively licensed a technology of the MPI for Biophysical Chemistry in Göttingen and has launched the MacroDSF, an instrument aimed at helping research institutions, pharmaceutical companies, and contract research organizations solve problems in structural biology. [more]
Teaser 1509697238

How the gene copying machine starts

November 03, 2017
As a molecular "copying machine" the RNA Polymerase II is responsible for the first step on the way from a gene to a protein: It makes a duplicate of the genetic instructions. This copying process is termed transcription. Scientists at the MPI for Biophysical Chemistry now succeeded in determining the three-dimensional structure of the polymerase together with all other factors important for the start of transcription - the so-called pre-initiation complex - in atomic detail, a milestone in transcriptional research. (in German) [more]
Teaser 1509547049

Kim Nasmyth invited for
Karl Friedrich Bonhoeffer Award Lecture

November 01, 2017
With the award lecture, the MPI for Biophysical Chemistry honors the British geneticist Kim Nasmyth, Whitley professor at the University of Oxford, for his groundbreaking research on the regulation of cell division. The talk takes place on November 8, 2017, at 2 pm in the Manfred Eigen Hall and will be held in English. Everyone interested is cordially invited. (in German) [more]
Teaser 1509090043

Vlad Pena elected as EMBO Young Investigator

October 27, 2017
Vlad Pena at the MPI for Biophysical Chemistry is one of 28 scientists from eleven different countries being appointed EMBO Young Investigator by the European Molecular Biology Organization (EMBO) this year. During their three-year tenure, EMBO Young Investigators receive a range of benefits, including an award of 15,000 euros and possible additional funds to support the establishment of their first independent laboratories. (in German) [more]
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