Henning Urlaub
Research Group Leader, Professor at the University of Göttingen
Phone:+49 551 201-1060Fax:+49 551 201-1197

Henning Urlaub

Bioanalytical Mass Spectrometry

The group works on the analysis of proteins, protein complexes, nucleic acids and ribonucleoprotein (RNP) complexes, using electrospray ionisation (ESI) and matrix-assisted laser desorption/ionisation (MALDI) mass spectrometry.

Our central research topics are in the development of methods for the efficient and sensitive analysis of protein content (proteomics), the detection of (post-translational) modifications and the mass-spectrometric quantification of protein components.

A major area of our activity – in collaboration with the Department of Cellular Biochemistry – is the identification of protein-RNA contact sites in native protein-RNA complexes following cross-linking. A further central area is the mass-spectrometric analysis of integral membrane proteins, in collaboration with the Department of Neurobiology. We also collaborate intensively with the Institute of Molecular and Cellular Immunology at the UMG of the Georg-August-University Göttingen in the quantitative mass spectrometrical analyses of B-cell and other cell signalling processes. The core facility Mass Spectrometry is part of the Bioanalytical Mass Spectrometry Group.

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