Max Planck Institute for Biophysical Chemistry

Emerging Topics in Biomolecular Magnetic Resonance

Emerging Topics in Biomolecular Magnetic Resonance

Presenting frontier research in magnetic resonance in biological systems

Organized by

Loren Andreas, Stefan Glöggler, Christian Griesinger, Mei Hong, Óscar Millet, Arthur G. Palmer, Markus Zweckstetter

Weekly on Thursday

7 a.m. PST (San Francisco) / 10 a.m. EST (New York) / 4 p.m. CST (Berlin) / 7.30 p.m IST (India) / 10 p.m. CST (Peking)

Register here for the Online Seminar

Online Seminar

Thursday, 29^th of July 2021

Investigating a-Synuclein amyloid seeding processes by NMR

Jean Baum (Rutgers University)

Higher fields and faster spinning: new opportunities for protein NMR

Beat Meier (ETH Zürich)

Thursday, 22^nd of July 2021

NMR studies of the HIV-1 RNA Packaging Signal

Michael F. Summers (University of Maryland)

The amyloid structure of RIPK3 (receptor interacting protein kinase 3) of mouse and human in cell necroptosis

Jun-Xia Lu (ShanghaiTech University)

Thursday, 15^th of July 2021

Solution NMR of phase separated disordered proteins associated with cancer and neurodegeneration

Nicolas Fawzi (Brown University)

Drugs in Cells

Lyndon Emsely (École Polytechnique Fédérale de Lausanne)

Thursday, 1^st of July 2021

Hyperpolarized water with dissolution-DNP and UV radicals

Jan Henrik Ardenkjær-Larsen (Technical University of Denmark)

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De novo structure determination of organic compounds from multi-alignment datasets: chances and challenges

Christina Thiele (Technical University of Darmstadt)

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Thursday, 10^th of June 2021

Peptide-mediated lipid organization, structure, and dynamics in pulmonary surfactant

Joanna Long (University of Florida/Florida State University)

Quantitative Protein Order/Disorder Assessment Using NMR Chemical Shifts

Frans Mulder (Aarhus University)

Thursday, 3^rd of June 2021

19F NMR Inspired Studies of GPCR Activation and the Connection to Pharmacology - A Non-Wikipedia Perspective

Scott Prosser (University of Toronto)

NMR spectroscopy applied to drug discovery and in metabolism characterization

Óscar Millet (CIC bioGUNE)

Thursday, 27^th of May 2021

Characterization of Biotherapeutics by Chemometric Analysis of NMR Spectra

Frank Delaglio (NIST & University of Maryland)

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NMR detection of light-dependent processes in membrane

Clemens Glaubitz (Goethe-Universitat Frankfurt am Main)

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Thursday, 20^th of May 2021

Comparative assessment of protein higher order structure in biopharmaceutical development using NMR and chemometric analysis

Hai-Young Kim (Pfizer, Inc.)

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Detection of a bound water molecule proton in a membrane protein pore

Loren Andreas (Max Planck Institute for Biophysical Chemistry)

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Thursday, 13^th of May 2021

Capturing the high-resolution structure of a low-populated aromatic ring flipping intermediate

Malene Ringkjøbing Jensen (Institut de Biologie Structurale, Grenoble)

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Protein folding and misfolding at the membrane surface

Alfonso De Simone (University of Naples Federico II)

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Thursday, 6^th of May 2021

An insight into stem cell metabolism with NMR metabolomics

Ana Gil (University of Aveiro)

The RNA binding, droplet formation and disease mechanism of FUS as probed by NMR

Frédéric Allain (ETH Zürich) more

Thursday, 29th of April 2021

The outer membrane insertase BAM as an antibiotic target

Sebastian Hiller (University of Basel)

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Relaxation dispersion under fast magic-angel spinning

Petra Rovó (Ludwig Maximilians University Munich) more

Thursday, 22^nd of April 2021

Investigation of the lipidated C-terminus of RalA: mutually exclusive binding to membranes and calmodulin

Helen Mott (University of Cambridge)

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SHACA, novel universal rotation pulses, and orientational constraints: tools and concepts for bio-NMR

Burkhard Luy (Karlsruhe Institute of Technology)

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Thursday, 15^th of April 2021

Probing submillisecond, pre-nucleation oligomerization of huntingtin exon-1 by NMR

Marius Clore (NIDDK, NIH)

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Structural dynamics of membrane proteins by NMR with fast MAS

Guido Pintacuda (Université de Lyon)

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Thursday, 8^th of April 2021

In-cell EPR: latest developments for membrane proteins

Enrica Bordignon (Ruhr University Bochum)

Filling the Knowledge Gap of the HIV-1 Spike Structure and Implication to Vaccine Development

James Chou (Harvard Medical School)

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Thursday, 1^st of April 2021

Helix-helix interactions of receptor tyrosine kinases

Anne Ulrich (Karlsruhe Institute of Technology)

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Fast assignment of protein hotspots with Focused Spectroscopy (FOSY)

Vladislav Orekhov (University of Gothenburg)

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Thursday, 25^th of March 2021

In-cell NMR: a powerful approach for drug and fragment screening

Lucia Banci (CERM/University of Florence)

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Interactions between small molecules and Aβ amyloid fibrils probed by MAS solid-state NMR

Bernd Reif (Technical University Munich)

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Thursday, 18^th of March 2021

Paramagnetic probes for NMR and EPR: Lock up the metals!

Marcellus Ubbink (Universiteit Leiden)

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Integrated Structural Biology of HIV-1 Assemblies

Tatyana Polenova (University of Delaware)

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Thursday, 11^th of March 2021

Copper Ions and Protein Aggregation: From Amyloids in Diabetes to Non-Amyloids in Cataracts Disease

Liliana Quintanar (Cinvestav, Mexico)

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Methyl resonance assignments, from methyl NOEs: Fact or Fiction?

Nikolaos Sgourakis (University of Pennsylvania)

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Thursday, 4^th of March 2021

Disordered complexes involving highly charged proteins

Birthe Kragelund (University of Copenhagen)

New Insights in COVID-19 from NMR Metabolomics

Ulrich Günther (University of Lübeck)

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Thursday, 25^th of February 2021

Putting annoying chemical exchanges to good use in the solution-state NMR of sugars, proteins and nucleic acids

Lucio Frydman (Weizmann Institute)

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Measuring the accuracy of NMR protein structures

Mike Williamson (University of Sheffield)

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Thursday, 18^th of February 2021

On automated structure and multi-state structure determination by NMR

Roland Riek (ETH Zürich)

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SSNMR-detected mobility in substrate-mediated protein activation

Patrick van der Wel (University of Groningen)

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Thursday, 11^th of February 2021

The conformational landscape of protein kinases in physiology and disease

Babis Kalodimos (St. Jude Children’s Research Hospital)

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Additive fabrication methods for reproducible, open-source NMR instrumentation

Rachel Martin (University of California, Irvine)

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Thursday, 4^th of February 2021

Understanding the molecular interactions underlying liquid-liquid phase separation of low-complexity domains

Tanja Mittag (St. Jude Children’s Research Hospital)

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Atomic structures and functional dynamics of rhomboid proteases, non-selective cation channels, and bacteriophage tail tubes

Adam Lange (Humboldt-University Berlin)

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Thursday, 28^th of January 2021

Molecular insights to calcified deposit formation from NMR

Francesca Marassi (Sanford Burnham Prebys)

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Breaking down the mechanism of a proton-coupled transporter

Katherine Henzler-Wildman (UW-Madison/NMRFAM)

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Thursday, 21^th of January 2021

Membrane Interactions of 40-Residue Beta-Amyloid Peptides

Wei Qiang (Binghamton University)

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¹H-detected solid-state NMR as an access to µs timescale conformational dynamics in large enzymes

Rasmus Linser (Technical University Dortmund)

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Thursday, 14^th of January 2021

Transient structure in IDPs from 3D NUS NMR of chemical denaturation

Ad Bax (NIDDK/NIH)

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Time Travel to the Past and Future – Evolution of energy landscapes for enzymes catalysis

Dorothee Kern (Brandeis University)

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