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Journal Article (22)

  1. 1.
    Journal Article
    Gentile, I.; Garro, H. A.; Delgado Ocaña, S.; Gonzalez, N.; Strohäker, T.; Schibich, D.; Quintanar, L.; Sambrotta, L.; Zweckstetter, M.; Griesinger, C. et al.; Menacho Márqueza, M.; Fernandez, C. O.: Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: Binding ligands, affinity and structural features. Metallomics 10 (10), pp. 1383 - 1389 (2018)
  2. 2.
    Journal Article
    Valiente-Gabioud, A. A.; Riedel, D.; Outeiro, T. F.; Menacho-Márquez, M. A.; Griesinger, C.; Fernandez, C. O.: Binding modes of phthalocyanines to amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 114 (5), pp. 1036 - 1045 (2018)
  3. 3.
    Journal Article
    Fonseca-Ornelas, L.; Schmidt, C. D.; Camacho-Zarco, A. R.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Small molecule-induced soluble oligomers of α-synuclein with helical structure. Chemistry. A European Journal 23 (53), pp. 13010 - 13014 (2017)
  4. 4.
    Journal Article
    Valiente-Gabioud, A. A.; Torres-Monserrat, V.; Molina-Rubino, L.; Binolfi, A.; Griesinger, C.; Fernandez, C. O.: Structural basis behind the interaction of Zn2+ with the protein α-synuclein and the Aβ peptide: A comparative analysis. Journal of Inorganic Biochemistry 117, pp. 334 - 341 (2012)
  5. 5.
    Journal Article
    Binolfi, A.; Quintanar, L.; Bertoncini, C. W.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of copper coordination to alpha-synuclein: relevance to Parkinson's disease. Coordination Chemistry Reviews 256 (19-20), pp. 2188 - 2201 (2012)
  6. 6.
    Journal Article
    Binolfi, A.; Fernandez, C. O.; Sica, M. P.; Delfino, J. M.; Santos, J.: Recognition between a short unstructured peptide and a partially folded fragment leads to the thioredoxin fold sharing native-like dynamics. Proteins: Structure, Function, and Bioinformatics 80 (5), pp. 1448 - 1464 (2012)
  7. 7.
    Journal Article
    Orcellet, M. L.; Fernandez, C. O.: Structures behind the amyloid aggregation of alpha-synuclein: an NMR based approach. Current Protein & Peptide Science 12 (3), pp. 188 - 205 (2011)
  8. 8.
    Journal Article
    Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), pp. 10668 - 10679 (2010)
  9. 9.
    Journal Article
    Paleologou, K. E.; Oueslati, A.; Shakked, G.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fernandez, C. O.; Schmid, A.; Chegini, F.; Gai, W. P. et al.; Chiappe, D.; Moniatte, M.; Schneider, B. L.; Aebischer, P.; Eliezer, D.; Zweckstetter, M.; Masliah, E.; Lashuel, H. A.: Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), pp. 3184 - 3198 (2010)
  10. 10.
    Journal Article
    Lamberto, G. R.; Binolfi, A.; Orcelett, M. L.; Bertoncini, C. O.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), pp. 21057 - 21062 (2009)
  11. 11.
    Journal Article
    Kim, H. Y.; Cho, M. K.; Kumar, A.; Maier, E.; Siebenhaar, C.; Becker, S.; Fernandez, C. O.; Lashuel, H. A.; Benz, R.; Lange, A. et al.; Zweckstetter, M.: Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), pp. 17482 - 17489 (2009)
  12. 12.
    Journal Article
    Cho, M. K.; Nodet, G.; Kim, H. K.; Jensen, M. R.; Bernado, P.; Fernandez, C. O.; Becker, S.; Blackledge, M.; Zweckstetter, M.: Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), pp. 1840 - 1846 (2009)
  13. 13.
    Journal Article
    Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), pp. 11801 - 11812 (2008)
  14. 14.
    Journal Article
    Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), pp. 5046 - 5048 (2008)
  15. 15.
    Journal Article
    Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, pp. 16895 - 16905 (2008)
  16. 16.
    Journal Article
    Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), pp. 3032 - 3033 (2007)
  17. 17.
    Journal Article
    Kim, H. Y.; Heise, H.; Fernandez, C. O.; Baldus, M.; Zweckstetter, M.: Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein. ChemBioChem 8 (14), pp. 1671 - 1674 (2007)
  18. 18.
    Journal Article
    Binolfi, A.; Rasia, R. M.; Bertoncini, C. W.; Ceolin, M.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement. Journal of the American Chemical Society 128 (30), pp. 9893 - 9901 (2006)
  19. 19.
    Journal Article
    Skora, L.; Cho, M. K.; Kim, H. Y.; Becker, S.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Charge-induced molecular alignment of intrinsically disordered proteins. Angewandte Chemie-International Edition 45 (42), pp. 7012 - 7015 (2006)
  20. 20.
    Journal Article
    Bertoncini, C. W.; Fernandez, C. O.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. Journal of Biological Chemistry 280, pp. 30649 - 30652 (2005)
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