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Journal Article (179)

  1. Journal Article
    Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: The 3-D arrangement for RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, pp. 539 - 542 (2001)
  2. Journal Article
    Urlaub, H.; Raker, V. A.; Kostka, S.; Luehrmann, R.: Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. EMBO Journal 20, pp. 187 - 196 (2001)
  3. Journal Article
    Vidovic, I.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Ficner, R.: Crystal structure of the spliceosomal 15.5 kD protein bound to a U4 snRNA fragment. Molecular Cell 6, pp. 1331 - 1342 (2001)
  4. Journal Article
    Will, C. L.; Luehrmann, R.: Spliceosomal U snRNP biogenesis, structure and function. Current Opinion in Cell Biology 13, pp. 290 - 301 (2001)
  5. Journal Article
    Will, C. L.; Luehrmann, R.: RNP remodeling with DExH/D Boxes. Science 291, pp. 1916 - 1917 (2001)
  6. Journal Article
    Will, C. L.; Schneider, C.; MacMilan, A. M.; Neubauer, G.; Wilm, M.; Luehrmann, R.; Query, C. C.: A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. EMBO Journal 20, pp. 4536 - 4546 (2001)
  7. Journal Article
    Brahms, H.; Raymackers, J.; Union, A.; de Keyser, F.; Meheus, L.; Luehrmann, R.: The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D 1 and D 3 contain symmetrical dimethylarginines which form a major B-cell epitope for anti-Sm autoantibodies. Journal of Biological Chemistry 275, pp. 17122 - 17129 (2000)
  8. Journal Article
    Makarov, E. M.; Makarova, O.; Achsel, T.; Luehrmann, R.: The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. Journal of Molecular Biology 298, pp. 567 - 575 (2000)
  9. Journal Article
    Reidt, U.; Reuter, K.; Achsel, T.; Ingelfinger, D.; Luehrmann, R.; Ficner, R.: Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin. Journal of Biological Chemistry 275, pp. 7439 - 7442 (2000)
  10. Journal Article
    Achsel, T.; Brahms, H.; Kastner, B.; Bachi, A.; Wilm, M.; Luehrmann, R.: A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO Journal 18, pp. 5789 - 5802 (1999)
  11. Journal Article
    Buehler, D.; Raker, V. A.; Luehrmann, R.; Fischer, U.: Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. Human Molecular Genetics 8, pp. 2351 - 2357 (1999)
  12. Journal Article
    Hartmuth, K.; Raker, V. A.; Huber, J.; Branlant, C.; Luehrmann, R.: An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles. Journal of Molecular Biology 285, pp. 133 - 147 (1999)
  13. Journal Article
    Kambach, C.; Walke, S.; Young, R.; Avis, J. M.; Fortelle, E. D. l.; Raker, V. A.; Luehrmann, R.; Li, J.; Nagai, K.: Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96, pp. 375 - 387 (1999)
  14. Journal Article
    Nottrott, S.; Hartmuth, K.; Fabrizio, P.; Urlaub, H.; Vidovic, I.; Ficner, R.; Luehrmann, R.: Functional interaction of a novel 15.5kD [U4/U6.U5]tri-snRNP protein with the 5′-stem-loop of U4 snRNA. EMBO Journal 18, pp. 6119 - 6133 (1999)
  15. Journal Article
    Paraskeva, E.; Izaurralde, E.; Bischoff, F. R.; Huber, J.; Kutay, U.; Hartmann, E.; Lührmann, R.; Görlich, D.: CRM1-mediated recycling of snurportin 1 to the cytoplasm. Journal of Cell Biology 145 (2), pp. 255 - 264 (1999)
  16. Journal Article
    Raker, V. A.; Hartmuth, K.; Kastner, B.; Luehrmann, R.: Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner. Molecular and Cellular Biology 19, pp. 6554 - 6565 (1999)
  17. Journal Article
    Reuter, K.; Nottrott, S.; Fabrizio, P.; Luehrmann, R.; Ficner, R.: Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15kD protein. Journal of Molecular Biology 294, pp. 515 - 525 (1999)
  18. Journal Article
    Segault, V.; Will, C. L.; Polycarpou-Schwarz, M.; Mattaj, I. W.; Branlant, C.; Luehrmann, R.: Conserved loop I of U5 snRNA is dispensible for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts. Molecular and Cellular Biology 19, pp. 2782 - 2790 (1999)
  19. Journal Article
    Will, C. L.; Schneider, C.; Reed, R.; Luehrmann, R.: Identification of both shared and distinct proteins in the major and minor spliceosomes. Science 284, pp. 2003 - 2005 (1999)

Book (4)

  1. Book
    Valcarcel, J.; Beggs, J.; Krainer, A.; Lührmann, R. (Eds.): The spliceosome and the regulation of alternative splicing. Cold Spring Harbor Lab. Pr., Cold Spring Harbor, N.Y. (accepted)
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